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PLoS pathogens, ISSN 1553-7374, 08/2018, Volume 14, Issue 8, pp. e1007264 - e1007264
.... Surprisingly, using the infected cell protein 0 (ICP0)-deleted HSV1 (HSV1-dICP0), we found that asTORi markedly augment infection in cancer cells and a mouse mammary cancer xenograft... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Catalytic Domain - drug effects | Humans | Cercopithecus aethiops | Eukaryotic Initiation Factor-4E - metabolism | Phosphoproteins - metabolism | Herpes Simplex - genetics | TOR Serine-Threonine Kinases - antagonists & inhibitors | Neoplasms - complications | Neoplasms - virology | Neoplasms - genetics | HEK293 Cells | Immediate-Early Proteins - deficiency | Gene Expression Regulation, Neoplastic - drug effects | Organisms, Genetically Modified | Eukaryotic Initiation Factor-4E - genetics | Vero Cells | Cells, Cultured | Signal Transduction - genetics | Phosphoproteins - genetics | Herpesvirus 1, Human - drug effects | Animals | Immediate-Early Proteins - genetics | TOR Serine-Threonine Kinases - chemistry | Herpes Simplex - pathology | Adaptor Proteins, Signal Transducing - genetics | Ubiquitin-Protein Ligases - deficiency | Herpes Simplex - complications | Herpesvirus 1, Human - genetics | Mice | Protein Kinase Inhibitors - pharmacology | Adaptor Proteins, Signal Transducing - metabolism | Neoplasms - pathology | Ubiquitin-Protein Ligases - genetics | Physiological aspects | Genetic aspects | Research | Genetic regulation | Herpes simplex virus | Cancer cells | TOR protein | Transplants & implants | Funding | Xenotransplantation | Herpes simplex | Viruses | Genomes | mRNA | Infections | Biochemistry | Kinases | Proteins | Immunology | Repressors | Transformed cells | Immunotherapy | Xenografts | Oncolysis | Inhibition | Supervision | Medical research | Protein biosynthesis | Rapamycin | Pharmacology | Children & youth | Infectious diseases | Inhibitors | Protein synthesis | Herpes viruses | Replication | Initiation factor eIF-4E | Tumors | Cancer | Index Medicus | TOR Serine-Threonine Kinases/antagonists & inhibitiors | Herpes Simplex/genetics | Herpes Simplex/pathology | Neoplasms/pathology | Eukaryotic Initiation Factor-4E/genetics | Ubiquitin-Protein Ligases/deficiency | Immediate-Early Proteins/genetics | Neoplasms/genetics | Herpes Simplex/complications | Life Sciences | Eukaryotic Initiation Factor-4E/metabolism | Neoplasms/complications | Herpesvirus 1, Human/genetics | Catalytic Domain/drug effects | Signal Transduction/genetics | Adaptator Proteins, Signal Transducing/genetics | Gene Expression Regulation, Neoplastic/drug effects | Phosphoproteins/genetics | Adaptator Proteins, Signal Transducing/metabolism | Immediate-Early Proteins/deficiency | Phosphoproteins/metabolims | TOR Serine-Threonine Kinases/chemistry | Protein Kinase Inhibitors/pharmacology | Herpesvirus 1, Human/drug effects | Ubiquitin-Protein Ligases/genetics | Neoplasms/virology
Journal Article
PLoS pathogens, ISSN 1553-7374, 08/2013, Volume 9, Issue 8, pp. e1003506 - e1003506
The small ubiquitin-like modifier (SUMO) is a protein that regulates a wide variety of cellular processes by covalent attachment of SUMO moieties to a diverse array of target proteins... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Basic-Leucine Zipper Transcription Factors - metabolism | Ubiquitins - genetics | Humans | Viral Proteins - metabolism | Small Ubiquitin-Related Modifier Proteins - genetics | Immediate-Early Proteins - metabolism | Proteolysis | Tumor Suppressor Proteins - genetics | HEK293 Cells | Trans-Activators - genetics | Herpesviridae Infections - genetics | Nuclear Proteins - genetics | Ubiquitins - metabolism | Herpesvirus 8, Human - physiology | Repressor Proteins - metabolism | Herpesviridae Infections - enzymology | Protein Structure, Tertiary | Tumor Suppressor Proteins - metabolism | Small Ubiquitin-Related Modifier Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Repressor Proteins - genetics | Viral Proteins - genetics | Nuclear Proteins - metabolism | Basic-Leucine Zipper Transcription Factors - genetics | Transcription Factors - genetics | Amino Acid Motifs | Transcription Factors - metabolism | Immediate-Early Proteins - genetics | Trans-Activators - metabolism | Mutation | Ubiquitin-Protein Ligases - genetics | Virus Replication - physiology | Promyelocytic Leukemia Protein | Index Medicus | Proteins | Phosphorylation | Leukemia | Colleges & universities | Genetic engineering | Genomes | Gene expression | Kaposis sarcoma
Journal Article
PLoS pathogens, ISSN 1553-7374, 05/2012, Volume 8, Issue 5, pp. e1002680 - e1002680
Kaposi's sarcoma-associated herpesvirus (KSHV) is the cause of Kaposi's sarcoma and body cavity lymphomas. KSHV lytic infection produces PAN RNA, a highly... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Chromatin - metabolism | Sequence Deletion | Virus Activation - physiology | Humans | Transcriptional Activation | Histones - biosynthesis | Neoplasm Proteins - metabolism | Histone Demethylases - genetics | Viral Proteins - metabolism | DNA-Binding Proteins - metabolism | Immediate-Early Proteins - metabolism | RNA, Messenger - biosynthesis | RNA, Viral - genetics | Chromatin Immunoprecipitation | Herpesvirus 8, Human - metabolism | HEK293 Cells | Trans-Activators - genetics | Trans-Activators - biosynthesis | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Herpesvirus 8, Human - physiology | Cell Line | Promoter Regions, Genetic | Immediate-Early Proteins - biosynthesis | RNA, Messenger - genetics | Viral Proteins - genetics | Herpesvirus 8, Human - genetics | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Jumonji Domain-Containing Histone Demethylases - genetics | Histone Demethylases - metabolism | Immediate-Early Proteins - genetics | Virus Replication | Gene Expression Regulation, Viral | Trans-Activators - metabolism | Jumonji Domain-Containing Histone Demethylases - metabolism | Human herpesvirus 8 | Viral genetics | Physiological aspects | Genetic aspects | Research | Virulence (Microbiology) | Health aspects | Proteins | Cell culture | Cloning | Genetic engineering | Genomes | Lymphomas | Gene expression | Kaposis sarcoma | Index Medicus
Journal Article
Journal of virology, ISSN 0022-538X, 07/2006, Volume 80, Issue 16, pp. 7995 - 8005
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
Life Sciences & Biomedicine | Science & Technology | Virology | RNA, Small Interfering - genetics | Autoantigens - metabolism | Nuclear Proteins - analysis | Tumor Suppressor Proteins - antagonists & inhibitors | Antigens, Nuclear - metabolism | Humans | Neoplasm Proteins - physiology | Neoplasm Proteins - antagonists & inhibitors | Immediate-Early Proteins - metabolism | Tumor Suppressor Proteins - genetics | Ubiquitin-Protein Ligases - analysis | Antigens, Nuclear - analysis | Immediate-Early Proteins - analysis | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Fibroblasts - chemistry | Fibroblasts - metabolism | Autoantigens - analysis | Genome, Viral | Gene Expression | Transcription Factors - physiology | Herpesvirus 1, Human - metabolism | Ubiquitin-Protein Ligases - metabolism | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Adaptor Proteins, Signal Transducing - analysis | Tumor Suppressor Proteins - physiology | Immediate-Early Proteins - genetics | Gene Expression Regulation, Viral | Nuclear Proteins - antagonists & inhibitors | Herpesvirus 1, Human - genetics | Nuclear Proteins - physiology | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin-Protein Ligases - genetics | Promyelocytic Leukemia Protein | Index Medicus | Virus-Cell Interactions
Journal Article
Nature reviews. Molecular cell biology, ISSN 1471-0080, 02/2015, Volume 16, Issue 3, pp. 167 - 177
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 08/2007, Volume 317, Issue 5840, pp. 944 - 947
Journal Article