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Journal of Neuroscience, ISSN 0270-6474, 04/2009, Volume 29, Issue 13, pp. 4200 - 4209
Although the tryptophan-degrading enzyme, indoleamine 2,3-dioxygenase (IDO), is a pivotal mediator of inflammation-induced depression, its mechanism of... 
QUINOLINIC ACID | TRYPTOPHAN-METABOLISM | IFN-GAMMA | MEDICALLY ILL | IMMUNE ACTIVATION | CENTRAL-NERVOUS-SYSTEM | SICKNESS BEHAVIOR | PROINFLAMMATORY CYTOKINES | TNF-ALPHA | DIFFERENTIAL REGULATION | NEUROSCIENCES | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Tumor Necrosis Factor-alpha - metabolism | Immobility Response, Tonic - physiology | Motor Activity - physiology | Chromatography, High Pressure Liquid - methods | Dose-Response Relationship, Immunologic | Mycobacterium bovis - immunology | Depression - pathology | Neuroglia | Brain - enzymology | Motor Activity - drug effects | Male | Interferon-gamma - metabolism | RNA, Messenger - metabolism | Lung - enzymology | Receptors, Tumor Necrosis Factor - therapeutic use | Depression - etiology | Depression - drug therapy | Etanercept | Up-Regulation - physiology | Immobility Response, Tonic - drug effects | Swimming | Animals, Newborn | Cytokines - metabolism | Receptors, Interferon - deficiency | Mice, Inbred C57BL | Cells, Cultured | Depression - microbiology | Immunoglobulin G - therapeutic use | Hindlimb Suspension - methods | Mice, Inbred ICR | Mice, Knockout | Brain - drug effects | Drug Synergism | Up-Regulation - drug effects | Illness Behavior - drug effects | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Interferon-gamma - administration & dosage | Lung - drug effects | Serotonin - metabolism | Tumor Necrosis Factor-alpha - administration & dosage | Mice | Index Medicus
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 08/2013, Volume 38, Issue 9, pp. 1609 - 1616
We have previously demonstrated that lipopolysaccharide (LPS) induces depressive-like behavior by activating indoleamine 2,3 dioxygenase (IDO; O'Connor et al,... 
AMPA receptor | depression | lipopolysaccharide | NMDA receptor | inflammation | ketamine | BACILLUS-CALMETTE-GUERIN | PSYCHIATRY | MACROPHAGES | INDOLEAMINE 2,3-DIOXYGENASE | INDUCTION | NEUROSCIENCES | HIPPOCAMPUS | QUINOLINIC ACID | SICKNESS | IMMUNE ACTIVATION | PHARMACOLOGY & PHARMACY | BRAIN | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Body Weight - drug effects | Motor Activity - drug effects | Male | Ketamine - antagonists & inhibitors | Lipopolysaccharides - antagonists & inhibitors | Brain - metabolism | Quinoxalines - pharmacology | Depression - drug therapy | Drug Interactions | Liver - drug effects | Depression - chemically induced | Immobility Response, Tonic - drug effects | Antidepressive Agents - pharmacology | Brain-Derived Neurotrophic Factor - biosynthesis | Ketamine - therapeutic use | Cytokines - metabolism | Drug Administration Schedule | Food Preferences - drug effects | Liver - metabolism | Mice, Inbred C57BL | Excitatory Amino Acid Antagonists - pharmacology | Antidepressive Agents - therapeutic use | Brain - drug effects | Eating - drug effects | Animals | Signal Transduction - drug effects | Mice | Ketamine - pharmacology | Receptors, AMPA - antagonists & inhibitors | Index Medicus | Antidepressants | biological psychiatry | animal models | behavioral science | bipolar | unipolar | Original
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 10/2013, Volume 38, Issue 11, pp. 2268 - 2277
Journal Article
Hippocampus, ISSN 1050-9631, 09/2017, Volume 27, Issue 9, pp. 1016 - 1029
Post‐traumatic stress disorder (PTSD) is characterized by memory disturbances following trauma. Acute predator threat has emerged as an ethological model of... 
contextual conditioning | sex differences | CREB shut‐off | CREB shut-off | BRAIN-REGIONS | LONG-TERM STRESS | ADULT RATS | CELL-PROLIFERATION | HISTONE ACETYLATION | SYNAPTIC PLASTICITY | NEUROSCIENCES | PREFRONTAL CORTEX | FOX ODOR | ANIMAL-MODEL | DENTATE GYRUS | Phosphorylation - physiology | Immobility Response, Tonic - physiology | MAP Kinase Signaling System - physiology | Maze Learning - physiology | Rats, Wistar | Stress Disorders, Post-Traumatic - metabolism | Rats | Male | Thiazoles - administration & dosage | Maze Learning - drug effects | Odorants | Blood Glucose - drug effects | CREB-Binding Protein - metabolism | Hippocampus - metabolism | Stress Disorders, Post-Traumatic - chemically induced | Animals | MAP Kinase Signaling System - drug effects | Sex Factors | Fear - psychology | Female | Immobility Response, Tonic - drug effects | Corticosterone - blood | Cyclic AMP - metabolism | Disease Models, Animal | Brain | Cellular signal transduction | Adenylic acid | Blood sugar | Post-traumatic stress disorder | Protein binding | Adenosine | Phosphorylation | AMP | Corticosterone | Hyperactivity | Spatial discrimination | Extracellular signal-regulated kinase | Cyclic AMP response element-binding protein | Trauma | Proteins | Learning | Signal transduction | Trimethylthiazoline | Odors | Post traumatic stress disorder | Rodents | Long term memory | Physiology | Transduction | Tonic immobility | Odor | Hippocampus | Index Medicus
Journal Article
Journal Article
Psychopharmacology, ISSN 0033-3158, 12/2008, Volume 201, Issue 3, pp. 435 - 442
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2010, Volume 30, Issue 21, pp. 7152 - 7167
Histone methyltransferases specific for the histone H3-lysine 9 residue, including Setdb1 (Set domain, bifurcated 1)/Eset/Kmt1e are associated with repressive... 
MODEL-BASED ANALYSIS | CHROMATIN REGULATION | MEMORY FORMATION | DNA METHYLATION | DEACETYLASE INHIBITORS | METABOTROPIC GLUTAMATE RECEPTORS | NEUROSCIENCES | NEURONAL PLASTICITY | METHYL-D-ASPARTATE | NUCLEUS-ACCUMBENS | TRANSGENIC MICE | Chromatin - metabolism | Immobility Response, Tonic - physiology | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | Fear - drug effects | Green Fluorescent Proteins - genetics | Protein Methyltransferases - metabolism | Neurons - ultrastructure | Excitatory Amino Acid Agents - pharmacology | Exploratory Behavior - drug effects | Behavior, Animal - drug effects | Excitatory Postsynaptic Potentials - genetics | Animals, Newborn | Membrane Potentials - drug effects | Adaptation, Ocular - genetics | Maze Learning - physiology | Food Preferences - drug effects | Histone-Lysine N-Methyltransferase | Affect - physiology | Behavior, Animal - physiology | Mice, Transgenic | Avoidance Learning - physiology | Avoidance Learning - drug effects | Mice | Membrane Potentials - genetics | Electroshock - adverse effects | Age Factors | Food Preferences - physiology | Protein Methyltransferases - genetics | Adaptation, Ocular - drug effects | Motor Activity - drug effects | Fear - physiology | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Receptors, N-Methyl-D-Aspartate - genetics | Exploratory Behavior - physiology | Transfection - methods | Neurons - physiology | Chromatin Immunoprecipitation - methods | Immobility Response, Tonic - drug effects | Neurons - drug effects | Sucrose - administration & dosage | Affect - drug effects | Conditioning (Psychology) - drug effects | Conditioning (Psychology) - physiology | Gene Expression Regulation - genetics | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Cells, Cultured | Gene Expression Regulation - physiology | Hippocampus - cytology | Maze Learning - drug effects | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - genetics | Gene Expression Regulation - drug effects | Motor Activity - genetics | Animals | Sweetening Agents - administration & dosage | Index Medicus | N-methyl-D-aspartate | depression | histone modification | epigenetic | excitatory postsynaptic potential | desensitization
Journal Article