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Blood, ISSN 0006-4971, 03/2006, Volume 107, Issue 6, pp. 2409 - 2414
Interleukin-2 (IL-2) is historically known as a T-cell growth factor. Accumulating evidence from knockout mice suggests that IL-2 is crucial for the... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 09/2010, Volume 116, Issue 10, pp. 1726 - 1733
Natural killer (NK) cells are innate effector lymphocytes that control the growth of major histocompatibility complex class I negative tumors. We show here... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 113, Issue 17, pp. 4008 - 4010
Considerable functional heterogeneity within human natural killer (NK) cells has been revealed through the characterization of distinct NK-cell subsets.... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 09/2011, Volume 118, Issue 10, pp. 2752 - 2762
Type 17 programmed CD161 hi CD8α + T cells contribute to mucosal immunity to bacteria and yeast. In early life, microbial colonization induces proliferation of... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 01/2007, Volume 109, Issue 2, pp. 653 - 660
Dendritic cells (DCs) play a key role in immune homeostasis and maintenance of self-tolerance. Tolerogenic DCs can be established by an encounter with... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 114, Issue 3, pp. 564 - 571
The Tec kinase Itk is critical for the development of αβ T cells as well as differentiation of CD4 + T cells into Th2 cells. Itk null mice have defects in the... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 12/2009, Volume 114, Issue 25, pp. 5182 - 5190
Killer immunoglobulin-like receptors (KIRs) play an essential role in the regulation of natural killer cell functions. KIR genes are highly polymorphic in... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 11/2017, Volume 130, Issue 21, pp. 2307 - 2316
Leniolisib, a novel, potent, selective oral PI3Kδ inhibitor was tested in patients with gain-of-function pathogenic variants in PIK3CD. Treatment was well... 
100 | Immunobiology and Immunotherapy
Journal Article
Blood, ISSN 0006-4971, 02/2011, Volume 117, Issue 7, pp. 2189 - 2199
HIV infection can result in depletion of total CD4 + T cells and naive CD8 + T cells, and in the generation of dysfunctional effector CD8 + T cells. In this... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 04/2013, Volume 121, Issue 14, pp. 2669 - 2677
Mutations in GATA2 are a cause of human NK cell deficiency. GATA2 is required for human NK cell maturation, specifically maintenance of the CD56 bright subset.... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 113, Issue 25, pp. 6361 - 6371
Homeostatic mechanism by which peripheral T-cell subsets are maintained in vivo remains largely unknown. Using a T-cell proliferation model under lymphopenic... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 04/2008, Volume 111, Issue 8, pp. 4273 - 4282
E3 ubiquitin ligases determine which intracellular proteins are targets of the ubiquitin conjugation pathway and thus play a key role in determining the... 
Immunobiology
Journal Article
2007, ISBN 0123737079, x, 295 p., [6] p. of plates
Book
04/2017, ISBN 9780128124079
eBook
Blood, ISSN 0006-4971, 02/2006, Volume 107, Issue 3, pp. 1063 - 1069
Bullous pemphigoid (BP) is an autoimmune disease associated with autoantibodies directed against the hemidesmosomal antigens anti-BP230 and anti-B180. Neonatal... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 04/2010, Volume 115, Issue 14, pp. 2818 - 2826
We analyzed the involvement of Wiskott-Aldrich syndrome protein (WASp), a critical regulator of actin cytoskeleton remodeling, in the control of natural killer... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 06/2007, Volume 109, Issue 12, pp. 5301 - 5307
Resistance to transforming growth factor (TGF)–β1–mediated growth suppression in tumor cells is often associated with the functional loss of TGF-β receptors.... 
Immunobiology
Journal Article
Blood, ISSN 0006-4971, 09/2014, Volume 124, Issue 12, pp. 1894 - 1904
IRF8 K108E mutation causes dendritic cell depletion, defective antigen presentation, and anergic T cells. IRF8 K108E mutant protein is functionally null and... 
100 | Immunobiology
Journal Article
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