Advanced drug delivery reviews, ISSN 0169-409X, 5/2017, Volume 114, pp. 3 - 18
Biomaterials employed to raise therapeutic immune responses have become a complex and active field. Historically, vaccines have been developed primarily to...
Autoimmunity | Inflammation | Vaccine | Wound Healing | Immunoengineering
Autoimmunity | Inflammation | Vaccine | Wound Healing | Immunoengineering
Journal Article
Biomaterials, ISSN 0142-9612, 2/2016, Volume 80, pp. 11 - 19
Biomaterial scaffolds are central to many regenerative strategies as they create a space for infiltration of host tissue and provide a platform to deliver...
immunomodulation | transplant | immunoengineering | scaffold | leukocyte
immunomodulation | transplant | immunoengineering | scaffold | leukocyte
Journal Article
ACS Nano, ISSN 1936-0851, 08/2017, Volume 11, Issue 8, pp. 7747 - 7757
Encapsulation of human embryonic stem-cell-differentiated beta cell clusters (hES-βC) holds great promise for cell replacement therapy for the treatment of...
nanotechnology | immunoengineering | diabetes | cell therapy | cell encapsulation device | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | immunoengineering diabetes | CHEMISTRY, MULTIDISCIPLINARY | REVERSAL | ISLET TRANSPLANTATION | IN-VITRO | INSULIN-PRODUCING CELLS | GENERATION | DIFFERENTIATION | OUTCOMES | PANCREATIC PROGENITORS | Stem Cell Transplantation | Cell- and Tissue-Based Therapy - methods | Animals | Nanotechnology - methods | Peritoneal Cavity | Nanostructures - chemistry | Polymers - chemistry | Mice | Cell Survival - physiology | Teratoma - metabolism | Index Medicus
nanotechnology | immunoengineering | diabetes | cell therapy | cell encapsulation device | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | immunoengineering diabetes | CHEMISTRY, MULTIDISCIPLINARY | REVERSAL | ISLET TRANSPLANTATION | IN-VITRO | INSULIN-PRODUCING CELLS | GENERATION | DIFFERENTIATION | OUTCOMES | PANCREATIC PROGENITORS | Stem Cell Transplantation | Cell- and Tissue-Based Therapy - methods | Animals | Nanotechnology - methods | Peritoneal Cavity | Nanostructures - chemistry | Polymers - chemistry | Mice | Cell Survival - physiology | Teratoma - metabolism | Index Medicus
Journal Article
Annual review of biomedical engineering, ISSN 1523-9829, 6/2019, Volume 21, Issue 1, pp. 267 - 297
In addition to their early-recognized functions in host defense and the clearance of apoptotic cell debris, macrophages play vital roles in tissue development,...
macrophage mechanics | immune cells | immunoengineering | resident macrophages | mechanotransduction | mechanotranscriptomics | Physiological aspects | Models | Macrophages | Phagocytosis | Plasticity
macrophage mechanics | immune cells | immunoengineering | resident macrophages | mechanotransduction | mechanotranscriptomics | Physiological aspects | Models | Macrophages | Phagocytosis | Plasticity
Journal Article
Biomaterials, ISSN 0142-9612, 10/2019, Volume 217, p. 119287
Nucleic acids have both extensive physiological function and structural potential, rendering them quintessential engineering biomaterials. As carriers of...
Nanoparticles | Immune activation | Liposomes | Hydrogels | Immunotherapy | Immunoengineering | OXIDIZED MITOCHONDRIAL-DNA | STING AGONISTS | NETTING NEUTROPHILS | MATERIALS SCIENCE, BIOMATERIALS | INFLAMMATORY RESPONSES | ENGINEERING, BIOMEDICAL | CPG MOTIFS | NEUTROPHIL EXTRACELLULAR TRAPS | IN-VITRO | INTERFERON-GAMMA | T-CELLS | INNATE IMMUNITY
Nanoparticles | Immune activation | Liposomes | Hydrogels | Immunotherapy | Immunoengineering | OXIDIZED MITOCHONDRIAL-DNA | STING AGONISTS | NETTING NEUTROPHILS | MATERIALS SCIENCE, BIOMATERIALS | INFLAMMATORY RESPONSES | ENGINEERING, BIOMEDICAL | CPG MOTIFS | NEUTROPHIL EXTRACELLULAR TRAPS | IN-VITRO | INTERFERON-GAMMA | T-CELLS | INNATE IMMUNITY
Journal Article
Annual Review of Biomedical Engineering, ISSN 1523-9829, 12/2015, Volume 17, Issue 1, pp. 317 - 349
Strategies to enhance, suppress, or qualitatively shape the immune response are of importance for diverse biomedical applications, such as the development of...
immunotherapy | immunoengineering | vaccination | Immunotherapy | Vaccination | Immunoengineering | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | DRUG-DELIVERY | ENGINEERING, BIOMEDICAL | CONTROLLED-RELEASE | SECONDARY LYMPHOID ORGANS | DENDRITIC CELL MATURATION | IN-VITRO | POLYMERIC NANOPARTICLES | ANTIGEN-PRESENTING CELL | REGULATORY T-CELLS | ADAPTIVE IMMUNE-RESPONSES | Immunization | Artificial Cells - immunology | Immunomodulation | Dendritic Cells - immunology | Humans | Immunologic Factors - administration & dosage | Antigen-Presenting Cells - immunology | Systems Biology | Proteins - immunology | Lymphoid Tissue - immunology | Biomedical Engineering | Nanoparticles | Animals | Biocompatible Materials | Nanotechnology | Tissue Engineering | Methods
immunotherapy | immunoengineering | vaccination | Immunotherapy | Vaccination | Immunoengineering | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | DRUG-DELIVERY | ENGINEERING, BIOMEDICAL | CONTROLLED-RELEASE | SECONDARY LYMPHOID ORGANS | DENDRITIC CELL MATURATION | IN-VITRO | POLYMERIC NANOPARTICLES | ANTIGEN-PRESENTING CELL | REGULATORY T-CELLS | ADAPTIVE IMMUNE-RESPONSES | Immunization | Artificial Cells - immunology | Immunomodulation | Dendritic Cells - immunology | Humans | Immunologic Factors - administration & dosage | Antigen-Presenting Cells - immunology | Systems Biology | Proteins - immunology | Lymphoid Tissue - immunology | Biomedical Engineering | Nanoparticles | Animals | Biocompatible Materials | Nanotechnology | Tissue Engineering | Methods
Journal Article
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ISSN 0892-6638, 04/2019, Volume 33, Issue 4, pp. 5089 - 5100
Recently, our group demonstrated that immobilized VEGF can capture flowing endothelial cells (ECs) from the blood in vitro and promote endothelialization and...
monocytes | endothelialization | immunoengineering | inflammation | SMALL-INTESTINAL SUBMUCOSA | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | TISSUE | HUMAN MONOCYTES | CELL BIOLOGY | ENDOTHELIAL PROGENITOR CELLS | SMALL-DIAMETER | IN-VIVO | BIOLOGY | ARTERIAL GRAFT | BLOOD-VESSELS | DIFFERENTIATION
monocytes | endothelialization | immunoengineering | inflammation | SMALL-INTESTINAL SUBMUCOSA | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | TISSUE | HUMAN MONOCYTES | CELL BIOLOGY | ENDOTHELIAL PROGENITOR CELLS | SMALL-DIAMETER | IN-VIVO | BIOLOGY | ARTERIAL GRAFT | BLOOD-VESSELS | DIFFERENTIATION
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 07/2019, Volume 116, Issue 30, pp. 14947 - 14954
Traumatic primary spinal cord injury (SCI) results in paralysis below the level of injury and is associated with infiltration of hematogenous innate immune...
spinal cord injury | INFLAMMATORY MONOCYTES | ACROLEIN | REGENERATION | MULTIDISCIPLINARY SCIENCES | nanomedicine | DELIVERY | RESPONSES | INHIBITION | MOTOR | nerve regeneration | REGULATORS | immunoengineering | AXONAL GROWTH | DEFICITS | Nanoparticles | Spinal cord injuries | Inflammation | Paralysis | Macrophages | Gene expression
spinal cord injury | INFLAMMATORY MONOCYTES | ACROLEIN | REGENERATION | MULTIDISCIPLINARY SCIENCES | nanomedicine | DELIVERY | RESPONSES | INHIBITION | MOTOR | nerve regeneration | REGULATORS | immunoengineering | AXONAL GROWTH | DEFICITS | Nanoparticles | Spinal cord injuries | Inflammation | Paralysis | Macrophages | Gene expression
Journal Article
Advanced Drug Delivery Reviews, ISSN 0169-409X, 05/2017, Volume 114, pp. 184 - 192
The compatibility of biomaterials is critical to their structural and biological function in medical applications. The immune system is the first responder to...
Wound repair | Wound healing | Regenerative medicine | Immunoengineering | Fibrosis | Adaptive immune response | T cells | Innate immune response | Interleukin expression | ECM | BREAST IMPLANTS | TISSUE | NEUTROPHILS | INNATE LYMPHOID-CELLS | INFLAMMATION | FOREIGN-BODY RESPONSE | IN-VIVO | REGULATORY T-CELLS | PHARMACOLOGY & PHARMACY | CYSTIC-FIBROSIS | MACROPHAGE POLARIZATION | Animals | Tissue Scaffolds - adverse effects | Foreign-Body Reaction - immunology | Humans | T-Lymphocytes - immunology | Immunity, Innate | Biocompatible Materials - adverse effects | Regenerative Medicine - methods | Macrophages - immunology | Regeneration - immunology | Biological products | Immune response | Macrophages | Medical colleges | Care and treatment | Engineering schools | Interleukins | Tissue engineering | Immunotherapy | Wounds and injuries
Wound repair | Wound healing | Regenerative medicine | Immunoengineering | Fibrosis | Adaptive immune response | T cells | Innate immune response | Interleukin expression | ECM | BREAST IMPLANTS | TISSUE | NEUTROPHILS | INNATE LYMPHOID-CELLS | INFLAMMATION | FOREIGN-BODY RESPONSE | IN-VIVO | REGULATORY T-CELLS | PHARMACOLOGY & PHARMACY | CYSTIC-FIBROSIS | MACROPHAGE POLARIZATION | Animals | Tissue Scaffolds - adverse effects | Foreign-Body Reaction - immunology | Humans | T-Lymphocytes - immunology | Immunity, Innate | Biocompatible Materials - adverse effects | Regenerative Medicine - methods | Macrophages - immunology | Regeneration - immunology | Biological products | Immune response | Macrophages | Medical colleges | Care and treatment | Engineering schools | Interleukins | Tissue engineering | Immunotherapy | Wounds and injuries
Journal Article