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Gastroenterology, ISSN 0016-5085, 2011, Volume 141, Issue 2, pp. 621 - 632
Background & Aims Epithelial cells that cover the intestinal mucosal surface maintain immune homeostasis and tolerance in the gastrointestinal tract. However,... 
Gastroenterology and Hepatology | IgA | Inflammatory Bowel Disease | T Cell | Immune Response | CELLS | COMPLEX | ACTIVATION | POLYMERIC IMMUNOGLOBULIN RECEPTOR | INTESTINAL EPITHELIUM | TRANSPORT | INFLAMMATORY-BOWEL-DISEASE | ADAPTER | HOST-DEFENSE | INFECTION | GASTROENTEROLOGY & HEPATOLOGY | Tumor Necrosis Factor-alpha - metabolism | Intestinal Mucosa - metabolism | Adaptor Protein Complex mu Subunits - metabolism | Epithelial Cells - metabolism | Adaptor Protein Complex beta Subunits - deficiency | Humans | Cell Membrane Permeability | Crohn Disease - metabolism | Cell Membrane - physiology | Ribonucleases - metabolism | Adaptor Protein Complex 1 - metabolism | Th17 Cells - metabolism | Intestinal Mucosa - immunology | alpha-Defensins - metabolism | Adaptor Protein Complex beta Subunits - immunology | Cell Membrane - metabolism | beta-Defensins - metabolism | Colon | Receptors, Cytokine - metabolism | Colitis - immunology | Adaptor Protein Complex 1 - deficiency | Lipocalins - metabolism | Adaptor Protein Complex 1 - immunology | Immunoglobulin A - metabolism | Signal Transduction | Acute-Phase Proteins - metabolism | Down-Regulation | Oncogene Proteins - metabolism | Homeostasis - immunology | Epithelial Cells - pathology | S100 Proteins - metabolism | Muramidase - metabolism | Intestinal Mucosa - microbiology | Mice, Knockout | Interleukin-17 - metabolism | Adaptor Protein Complex beta Subunits - metabolism | Animals | Colitis - microbiology | Proteins - metabolism | Ribonuclease, Pancreatic - metabolism | Lipocalin-2 | Cathelicidins - metabolism | Epithelial Cells - immunology | Receptors, Cytokine - immunology | Mice | Intestinal Mucosa - pathology | Medical colleges | Fc receptors | Gastrointestinal diseases | Homeostasis | Biological response modifiers | Immunoglobulin A | T cells
Journal Article
European Journal of Immunology, ISSN 0014-2980, 01/2015, Volume 45, Issue 1, pp. 89 - 100
The vitamin A metabolite retinoic acid (RA) has been reported to suppress Th1 responses and enhance Th2 responses. Here, we investigated whether differences in... 
Vitamin A | IgA | Intestine | Retinaldehyde dehydrogenase | FoxP3 | BALB/c | C57BL/6 | DEXTRAN SULFATE SODIUM | GUT | SMALL-INTESTINE | INNATE LYMPHOID-CELLS | IMMUNOLOGY | EXPERIMENTAL COLITIS | IN-VIVO | REGULATORY T-CELLS | RETINOIC-ACID-RECEPTOR | CD103(+) DENDRITIC CELLS | EXPRESSION | Th1 Cells - pathology | Dextran Sulfate | T-Lymphocytes, Regulatory - metabolism | Species Specificity | Retinal Dehydrogenase - metabolism | Immunity, Mucosal | Immunoglobulin A - genetics | Colitis - pathology | Intestines - metabolism | Th2 Cells - immunology | Th1 Cells - immunology | Intestines - immunology | T-Lymphocytes, Regulatory - pathology | Isoenzymes - immunology | T-Lymphocytes, Regulatory - immunology | Vitamin A - administration & dosage | Vitamin A - metabolism | Th1 Cells - metabolism | Isoenzymes - metabolism | Colitis - chemically induced | Colitis - immunology | Immunoglobulin Class Switching | Retinal Dehydrogenase - immunology | Th2 Cells - pathology | Gene Expression | Immunoglobulin A - metabolism | Intestines - pathology | Signal Transduction | Isoenzymes - genetics | Mice, Inbred C57BL | Retinal Dehydrogenase - genetics | Th2 Cells - metabolism | Mucous Membrane - metabolism | Mucous Membrane - pathology | Animals | Mucous Membrane - immunology | Immunoglobulin A - immunology | Colitis - metabolism | Mice | Mice, Inbred BALB C | Dextran | Metabolites | Physiological aspects | B cells | Colitis | Immunoglobulin A | T cells | Tretinoin | Inflammatory bowel disease | Metabolism | Rodents
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 01/2015, Volume 26, Issue 1, pp. 91 - 98
We have previously shown that high-protein (HP) diet ingestion causes marked changes in the luminal environment of the colonic epithelium. This study aimed to... 
Mucus | Goblet cells | Basal gut inflammatory status | Intestine | High-protein diet | IMMUNE HOMEOSTASIS | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GUT | MICROBIOTA | NUTRITION & DIETETICS | EPITHELIAL-CELLS | METABOLISM | CONSEQUENCES | FERMENTATION | NITROGEN | THREONINE | Immunohistochemistry | Dietary Proteins - administration & dosage | Up-Regulation | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Rats, Wistar | Enterocytes - metabolism | Epithelial Cells - drug effects | Transforming Growth Factor beta1 - metabolism | Colon - drug effects | Immunoglobulin A - genetics | Ileum - metabolism | Fatty Acids, Volatile - genetics | Goblet Cells - drug effects | Male | Fatty Acids, Volatile - metabolism | Intestinal Mucosa - drug effects | Ileum - drug effects | Interleukin-10 - metabolism | Interleukin-6 - metabolism | Mucin-3 - genetics | Tight Junctions - metabolism | Immunoglobulin A - metabolism | Mucin-3 - metabolism | Interleukin-6 - genetics | Acetates - metabolism | Down-Regulation | CD4-Positive T-Lymphocytes - metabolism | Rats | Toll-Like Receptor 4 - genetics | Interleukin-13 - metabolism | Toll-Like Receptor 4 - metabolism | Colon - metabolism | Animals | Diet | Enterocytes - drug effects | Physiological aspects | Cytokines | Gene expression | Mucins | Life Sciences | Food and Nutrition
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, p. e27944
Inflammatory mediators in the tumour microenvironment promote tumour growth, vascular development and enable evasion of anti-tumour immune responses, by... 
MIGRATION | ACTIVATION | FUNCTIONAL MATURATION | ANGIOGENESIS | VEGF | MULTIDISCIPLINARY SCIENCES | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | CXC CHEMOKINES | G-CSF | T-CELLS | ENDOTHELIAL GROWTH-FACTOR | Antigens, CD - immunology | Immunoglobulins - immunology | Membrane Glycoproteins - metabolism | Chemokine CCL2 - immunology | Coculture Techniques | Dendritic Cells - immunology | Humans | Culture Media, Conditioned - pharmacology | Male | Vascular Endothelial Growth Factor A - metabolism | Chemokine CXCL5 - metabolism | Interferon-gamma - metabolism | Chemokine CXCL1 - pharmacology | Lipopolysaccharides - immunology | Antigens, CD - metabolism | Immunoglobulins - metabolism | Chemokine CXCL5 - pharmacology | Flow Cytometry | Female | Chemokine CCL2 - metabolism | Membrane Glycoproteins - immunology | B7-2 Antigen - immunology | Chemokine CXCL1 - metabolism | HLA-DR Antigens - metabolism | Vascular Endothelial Growth Factor A - pharmacology | Colorectal Neoplasms - metabolism | Dendritic Cells - metabolism | Tumor Microenvironment - drug effects | Enzyme-Linked Immunosorbent Assay | Intercellular Adhesion Molecule-1 - immunology | Tissue Culture Techniques | Cells, Cultured | Vascular Endothelial Growth Factor A - immunology | Tumor Microenvironment - immunology | B7-2 Antigen - metabolism | Cell Differentiation - immunology | Chemokine CXCL1 - immunology | Intercellular Adhesion Molecule-1 - metabolism | Colorectal Neoplasms - immunology | Chemokine CCL2 - pharmacology | Cell Differentiation - drug effects | Chemokine CXCL5 - immunology | Interferon-gamma - immunology | Lipopolysaccharides - pharmacology | Aged | HLA-DR Antigens - immunology | Colorectal Neoplasms - pathology | Culture Media, Conditioned - metabolism | Care and treatment | Dendritic cells | Vascular endothelial growth factor | Colorectal cancer | Tumors | CD86 antigen | Colorectal carcinoma | Biochemistry | Metastasis | Kinases | Lipopolysaccharides | Proteins | Angiogenesis | Signal transduction | Lymphocytes | Inhibition | Pretreatment | Conditioning | Antigens | Immune response | Cytokines | Maturation | Secretion | Neutrophils | Interleukin 12 | CD80 antigen | Inflammation | CD83 antigen | Interleukin 10 | Ligands | Histocompatibility antigen HLA | Prostate cancer | Chemokines | Monocyte chemoattractant protein 1 | Cancer | Apoptosis
Journal Article
Circulation Research, ISSN 0009-7330, 09/2014, Volume 115, Issue 8, pp. 738 - 750
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 07/2015, Volume 5, Issue 1, p. 11162
Journal Article
Journal of Medical Microbiology, ISSN 0022-2615, 12/2013, Volume 62, Issue 12, pp. 1815 - 1822
Journal Article
Clinical Immunology, ISSN 1521-6616, 2014, Volume 153, Issue 2, pp. 264 - 276
Abstract As vaccine-elicited antibodies have now been associated with HIV protective efficacy, a thorough understanding of mucosal and systemic B-cell... 
Allergy and Immunology | SIV/SHIV rhesus macaque model | Plasmablasts/plasma cells | Homing markers