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Journal Article
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 04/2013, Volume 92, Issue 4, pp. 530 - 546
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2013, Volume 110, Issue 16, pp. 6470 - 6475
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 23, pp. 9566 - 9571
Compaction and looping of the ∼2.5-Mb Igh locus during V(D)J rearrangement is essential to allow all V H genes to be brought in proximity with D H -J H... 
Immunoglobulins | Chromatin | B lymphocytes | Genes | Cell lines | Stem cells | Retroviridae | Genetic loci | Cells | Binding sites | ChIP-seq | Insulator | Boundary element | Lymphocytes | V(D)J recombination | lymphocytes | boundary element | CHROMATIN | MULTIDISCIPLINARY SCIENCES | HEAVY-CHAIN GENE | CONFORMATION | REARRANGEMENTS | IMMUNOGLOBULIN LOCI | ORGANIZATION | ELEMENTS | LYMPHOCYTE DEVELOPMENT | SWITCH | insulator | Precursor Cells, B-Lymphoid - metabolism | Phosphoproteins - metabolism | DNA, Antisense - genetics | Chromatin Immunoprecipitation | RNA Interference | Cell Cycle Proteins - genetics | Transcription, Genetic | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Cell Line | Chromosomal Proteins, Non-Histone - metabolism | Mice, Inbred C57BL | Cell Cycle Proteins - metabolism | Cells, Cultured | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Binding Sites - genetics | Phosphoproteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Chromosomal Proteins, Non-Histone - genetics | Mice, Knockout | Animals | CCCTC-Binding Factor | Immunoglobulin Heavy Chains - metabolism | Protein Binding | Enhancer Elements, Genetic - genetics | Mice | Immunoglobulin Heavy Chains - genetics | RNA, Antisense - genetics | Proteins | Signal transduction | Genomics | Viruses | Chromosomes | Index Medicus | Enhancers | cohesin | Transcription | Heavy chains | Antibodies | Antisense | genomics | Regulatory sequences | Compaction | Rosette | Conformation | Biological Sciences
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2016, Volume 17, Issue 3, pp. 331 - 343
The transcription factor Blimp-1 is necessary for the generation of plasma cells. Here we studied its functions in plasmablast differentiation by identifying... 
RNA-POLYMERASE-II | MATURE B | GERMINAL CENTER B | LYMPHOPOIESIS | MESSENGER-RNA | REPRESSION | ER STRESS | GENE-EXPRESSION | IMMUNOLOGY | ELONGATION-FACTOR | T-CELLS | Humans | Cell Movement - genetics | Cell Migration Assays, Leukocyte | Cell Movement - immunology | Cell Differentiation - genetics | Flow Cytometry | Immunoglobulin kappa-Chains - immunology | Chromatin Immunoprecipitation | Mass Spectrometry | HEK293 Cells | Plasma Cells - metabolism | Electrophoretic Mobility Shift Assay | Transcription Factors - immunology | Immunoglobulin Heavy Chains - immunology | B-Lymphocytes - metabolism | Cell Adhesion - genetics | Enzyme-Linked Immunosorbent Assay | Gene Expression Regulation | Interferon Regulatory Factors - genetics | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Sequence Analysis, DNA | Cell Adhesion - immunology | Cell Differentiation - immunology | Immunoglobulin kappa-Chains - genetics | Interferon Regulatory Factors - immunology | Animals | B-Lymphocytes - immunology | Sequence Analysis, RNA | High-Throughput Nucleotide Sequencing | Mice | Immunoglobulin Heavy Chains - genetics | Plasma Cells - immunology | Positive Regulatory Domain I-Binding Factor 1 | Transcription factors | Plasma cells | Genetic research | Genetic aspects | Genetic transcription | Research | Cell differentiation | Health aspects | Index Medicus
Journal Article
PLoS pathogens, ISSN 1553-7366, 2013, Volume 9, Issue 5, pp. e1003342 - e1003342
New broad and potent neutralizing HIV-1 antibodies have recently been described that are largely dependent on the gp120 N332 glycan for Env recognition.... 
SYSTEM | COMPLEX | POTENT NEUTRALIZATION | PROTEIN | SOLUBLE CD4 | ENVELOPE GLYCOPROTEIN | ELECTRON-MICROSCOPY | MICROBIOLOGY | CONFORMATIONAL EPITOPE | VIROLOGY | IMMUNODEFICIENCY-VIRUS TYPE-1 | INFLUENZA-A VIRUSES | PARASITOLOGY | HIV Envelope Protein gp120 - genetics | Humans | Immunoglobulin Heavy Chains - chemistry | Crystallography, X-Ray | Epitopes - immunology | HIV Envelope Protein gp120 - immunology | Allosteric Regulation - immunology | Antibodies, Neutralizing - immunology | HEK293 Cells | Protein Structure, Quaternary | HIV Envelope Protein gp120 - chemistry | Glycoproteins - chemistry | Immunoglobulin Heavy Chains - immunology | CD4 Antigens - genetics | Glycoproteins - genetics | CD4 Antigens - immunology | Allosteric Regulation - genetics | Antibodies, Neutralizing - genetics | Epitopes - genetics | HIV-1 - genetics | Glycoproteins - immunology | HIV-1 - immunology | CD4 Antigens - chemistry | Antibodies, Neutralizing - chemistry | Antibodies, Viral - chemistry | Antibodies, Viral - immunology | Epitopes - chemistry | Binding Sites, Antibody | Antibodies, Viral - genetics | Immunoglobulin Heavy Chains - genetics | Immune response | HIV antibodies | Analysis | Crystals | Research | Structure | Identification and classification | Index Medicus | Competition | Medical research | Acquired immune deficiency syndrome | HIV | AIDS | Human immunodeficiency virus | Binding sites
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 7, pp. 755 - 765
Acute systemic lupus erythematosus (SLE) courses with surges of antibody-secreting cells (ASCs) whose origin, diversity and contribution to serum... 
RESPONSES | ACTIVATION | MEMORY B-CELLS | AFFINITY MATURATION | AUTOIMMUNITY | PERIPHERAL-BLOOD | GERMINAL CENTER | IMMUNOLOGY | MONOCLONAL-ANTIBODIES | SLE | ANTIGEN | Autoantibodies - metabolism | Cell Proliferation | Immunoglobulin G - blood | Humans | Immunoglobulin Variable Region - metabolism | Lupus Erythematosus, Systemic - metabolism | Molecular Sequence Data | Immunoglobulin Variable Region - immunology | Tandem Mass Spectrometry | Antibody Diversity - genetics | Flow Cytometry | Antibody Diversity - immunology | Immunoglobulin G - immunology | Single-Cell Analysis - methods | Base Sequence | Proteome - immunology | Clone Cells - immunology | Lupus Erythematosus, Systemic - immunology | Proteomics - methods | Immunoglobulin Heavy Chains - immunology | B-Lymphocytes - metabolism | Amino Acid Sequence | Antibody-Producing Cells - metabolism | Acute Disease | Proteome - analysis | Clone Cells - metabolism | Sequence Homology, Amino Acid | Autoantibodies - immunology | Antibody-Producing Cells - immunology | B-Lymphocytes - immunology | Immunoglobulin G - genetics | Influenza Vaccines - immunology | Lupus Erythematosus, Systemic - genetics | Immunoglobulin Heavy Chains - metabolism | Immunoglobulin Variable Region - genetics | Autoantibodies - genetics | Tetanus Toxoid - immunology | Immunoglobulin Heavy Chains - genetics | Systemic lupus erythematosus | Immune response | Autoantibodies | Development and progression | Genetic aspects | Nucleotide sequencing | Identification and classification | Methods | DNA sequencing | Index Medicus
Journal Article