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Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 7, pp. 755 - 765
Acute systemic lupus erythematosus (SLE) courses with surges of antibody-secreting cells (ASCs) whose origin, diversity and contribution to serum... 
RESPONSES | ACTIVATION | MEMORY B-CELLS | AFFINITY MATURATION | AUTOIMMUNITY | PERIPHERAL-BLOOD | GERMINAL CENTER | IMMUNOLOGY | MONOCLONAL-ANTIBODIES | SLE | ANTIGEN | Autoantibodies - metabolism | Cell Proliferation | Immunoglobulin G - blood | Humans | Immunoglobulin Variable Region - metabolism | Lupus Erythematosus, Systemic - metabolism | Molecular Sequence Data | Immunoglobulin Variable Region - immunology | Tandem Mass Spectrometry | Antibody Diversity - genetics | Flow Cytometry | Antibody Diversity - immunology | Immunoglobulin G - immunology | Single-Cell Analysis - methods | Base Sequence | Proteome - immunology | Clone Cells - immunology | Lupus Erythematosus, Systemic - immunology | Proteomics - methods | Immunoglobulin Heavy Chains - immunology | B-Lymphocytes - metabolism | Amino Acid Sequence | Antibody-Producing Cells - metabolism | Acute Disease | Proteome - analysis | Clone Cells - metabolism | Sequence Homology, Amino Acid | Autoantibodies - immunology | Antibody-Producing Cells - immunology | B-Lymphocytes - immunology | Immunoglobulin G - genetics | Influenza Vaccines - immunology | Lupus Erythematosus, Systemic - genetics | Immunoglobulin Heavy Chains - metabolism | Immunoglobulin Variable Region - genetics | Autoantibodies - genetics | Tetanus Toxoid - immunology | Immunoglobulin Heavy Chains - genetics | Systemic lupus erythematosus | Immune response | Autoantibodies | Development and progression | Genetic aspects | Nucleotide sequencing | Identification and classification | Methods | DNA sequencing
Journal Article
Science, ISSN 0036-8075, 12/2011, Volume 334, Issue 6060, pp. 1289 - 1293
Antibodies against the CD4 binding site (CD4bs) on the HIV-1 spike protein gp120 can show exceptional potency and breadth. We determined structures of... 
T lymphocytes | Hydrogen bonds | REPORTS | Antibodies | Atoms | Viruses | Grants | Inhibitory concentration 50 | Geometric lines | Superposition principle | Binding sites | INDIVIDUALS | NEUTRALIZING ANTIBODIES | PROTECTION | MULTIDISCIPLINARY SCIENCES | VACCINE | IMMUNODEFICIENCY-VIRUS TYPE-1 | RECEPTOR | BROAD | GP120 | MONOCLONAL-ANTIBODIES | BINDING | Humans | Antibodies, Neutralizing - metabolism | Immunoglobulin Heavy Chains - chemistry | Molecular Sequence Data | Crystallography, X-Ray | HIV Envelope Protein gp120 - metabolism | HIV Envelope Protein gp120 - immunology | Antibodies, Neutralizing - immunology | Molecular Mimicry | HIV Antibodies - immunology | Immunoglobulin Fab Fragments - metabolism | Protein Engineering | Mutant Proteins - immunology | HIV Envelope Protein gp120 - chemistry | Binding Sites | Immunoglobulin Heavy Chains - immunology | HIV Antibodies - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Antibody Affinity | Mutant Proteins - metabolism | HIV Antibodies - chemistry | HIV-1 - immunology | CD4 Antigens - chemistry | Antibodies, Neutralizing - chemistry | Immunoglobulin Fab Fragments - chemistry | Mutant Proteins - chemistry | AIDS Vaccines | Hydrophobic and Hydrophilic Interactions | Immunoglobulin Heavy Chains - metabolism | Protein Conformation | Immunoglobulin Fab Fragments - immunology | Complementarity Determining Regions | CD4 Antigens - metabolism | Research | HIV antibodies | CD4 lymphocytes | Protein binding | Amino acids | Immunoglobulins | Vaccines | Human immunodeficiency virus--HIV | Crystal structure
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 10/2012, Volume 209, Issue 11, pp. 2079 - 2097
One component of memory in the antibody system is long-lived memory B cells selected for the expression of somatically mutated, high-affinity antibodies in the... 
B-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | CLONAL SELECTION | GERMINAL-CENTER FORMATION | MURINE MEMORY | AFFINITY MATURATION | LIVED PLASMA-CELLS | PRIMARY IMMUNIZATION | GENE-EXPRESSION | IMMUNOLOGY | T-CELLS | PRIMARY IMMUNE-RESPONSE | Antibodies - metabolism | Oligonucleotide Array Sequence Analysis | Germinal Center - immunology | Immunoglobulin Variable Region - metabolism | Molecular Sequence Data | Male | Gene Expression Profiling | Immunoglobulin Variable Region - immunology | DNA-Binding Proteins - metabolism | Signal Transduction - immunology | Flow Cytometry | Immunoglobulin G - immunology | Antibodies - immunology | Female | Germ Cells - metabolism | Immunoglobulin Heavy Chains - immunology | B-Lymphocytes - metabolism | Immunologic Memory - immunology | DNA-Binding Proteins - immunology | Mice, Inbred C57BL | Mice, Transgenic | Signal Transduction - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Sequence Analysis, DNA | Mice, Knockout | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Immunoglobulin G - genetics | Immunoglobulin Heavy Chains - metabolism | Antibodies - genetics | Immunoglobulin Variable Region - genetics | Mice | Mice, Inbred BALB C | Germ Cells - immunology | Immunoglobulin Heavy Chains - genetics | Immunoglobulin G - metabolism | Proto-Oncogene Proteins c-bcl-6
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2005, Volume 353, Issue 17, pp. 1793 - 1801
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 23, pp. 9566 - 9571
Journal Article