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The Journal of Immunology, ISSN 0022-1767, 11/2003, Volume 171, Issue 10, pp. 5215 - 5224
By substituting the H chain C region of IgM with that of IgG, IgA, or IgE, class switching enables Abs to acquire new effector functions that are crucial for... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | NECROSIS-FACTOR FAMILY | IN-VIVO | ACTIVATES TRANSCRIPTION | HUMAN B-CELLS | CD40 LIGAND | LYMPHOCYTE STIMULATOR | GERMINAL-CENTERS | IMMUNOLOGY | NF-KAPPA-B | EPSTEIN-BARR-VIRUS | T-Lymphocyte Subsets - immunology | Immunoglobulin Heavy Chains - biosynthesis | Viral Matrix Proteins - genetics | Herpesvirus 4, Human - genetics | Immunoglobulin alpha-Chains - genetics | Humans | Tumor Necrosis Factor-alpha - genetics | Molecular Sequence Data | Immunoglobulin alpha-Chains - biosynthesis | Tumor Necrosis Factor Ligand Superfamily Member 13 | Neuropeptides - physiology | Viral Matrix Proteins - physiology | Cytidine Deaminase - biosynthesis | Membrane Proteins - physiology | Recombination, Genetic | Base Sequence | Neuropeptides - biosynthesis | B-Lymphocyte Subsets - immunology | Immunoglobulin epsilon-Chains - biosynthesis | Adjuvants, Immunologic - physiology | Gene Expression Regulation - immunology | Lymphocyte Activation | Membrane Proteins - genetics | Cells, Cultured | Herpesvirus 4, Human - immunology | Up-Regulation - genetics | Adjuvants, Immunologic - biosynthesis | B-Lymphocyte Subsets - enzymology | Immunoglobulin epsilon-Chains - genetics | Nuclear Proteins | Immunoglobulin mu-Chains - genetics | Membrane Proteins - biosynthesis | B-Cell Activating Factor | B-Lymphocyte Subsets - metabolism | Up-Regulation - immunology | Immunoglobulin mu-Chains - biosynthesis | NF-kappa B - physiology | Tumor Necrosis Factor-alpha - physiology | HL-60 Cells | Transcription, Genetic - immunology | Promoter Regions, Genetic - immunology | Immunoglobulin Class Switching - genetics | Tumor Necrosis Factor-alpha - biosynthesis | Immunoglobulin Heavy Chains - genetics | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 10/2003, Volume 171, Issue 7, pp. 3816 - 3822
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2002, Volume 168, Issue 10, pp. 5014 - 5023
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 08/2005, Volume 202, Issue 4, pp. 505 - 516
Differentiation of B cells into plasma cells requires X-box binding protein-1 (XBP-1). In the absence of XBP-1, B cells develop normally, but very little... 
ENDOPLASMIC-RETICULUM MEMBRANE | MEDICINE, RESEARCH & EXPERIMENTAL | COMPLEX | UNFOLDED PROTEIN RESPONSE | MESSENGER-RNA | PROTEASOMAL DEGRADATION | ANTIBODY SECRETION | TRANSCRIPTION FACTOR XBP-1 | CYTOSOL | DIFFERENTIATION | IMMUNOLOGY | ANTIGEN RECEPTOR | Glycoproteins - metabolism | Protein Biosynthesis - immunology | Endoplasmic Reticulum - metabolism | Receptors, Antigen, T-Cell, alpha-beta - immunology | X-Box Binding Protein 1 | DNA-Binding Proteins - metabolism | Histocompatibility Antigens Class I - metabolism | Protein Transport - immunology | RNA, Messenger - biosynthesis | Plasma Cells - metabolism | Immunoglobulin Light Chains - immunology | Cell Line | CpG Islands - immunology | DNA-Binding Proteins - immunology | Immunoglobulin mu-Chains - immunology | Gene Expression Regulation - immunology | Histocompatibility Antigens Class I - immunology | Nuclear Proteins - metabolism | Nuclear Proteins - immunology | Regulatory Factor X Transcription Factors | Mice, Knockout | Gene Expression Regulation - drug effects | Immunoglobulin Light Chains - biosynthesis | Cell Differentiation - immunology | Immunoglobulin mu-Chains - genetics | Glycoproteins - immunology | Animals | Cell Differentiation - drug effects | Endoplasmic Reticulum - immunology | Immunoglobulin mu-Chains - biosynthesis | Lipopolysaccharides - pharmacology | Protein Biosynthesis - drug effects | Mice | Transcription Factors | Plasma Cells - immunology | Index Medicus
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 03/2009, Volume 182, Issue 6, pp. 3583 - 3596
Journal Article
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 10/2003, Volume 171, Issue 7, pp. 3343 - 3347
Journal Article
Nature Genetics, ISSN 1061-4036, 05/1994, Volume 7, Issue 1, pp. 13 - 21
Journal Article
The Journal of Immunology, ISSN 0022-1767, 07/2000, Volume 165, Issue 2, pp. 786 - 794
CD153 (CD30 ligand) is a member of the TNF ligand/cytokine family expressed on the surface of human B cells, Upon exposure to IL-4, a critical Ig class... 
HUMAN TONSIL | DENDRITIC CELLS | OX40 LIGAND | CD40 LIGAND | RECEPTOR | GERMINAL-CENTERS | SOMATIC MUTATION | FAMILY PROTEINS | IMMUNOLOGY | NF-KAPPA-B | VARIANT CD30 | Immunoglobulin alpha-Chains - genetics | Membrane Glycoproteins - metabolism | Humans | Membrane Glycoproteins - biosynthesis | Repressor Proteins | Immunoglobulin alpha-Chains - biosynthesis | Transcriptional Activation - immunology | Cytokines - physiology | Palatine Tonsil - immunology | CD28 Antigens - metabolism | Palatine Tonsil - cytology | Membrane Glycoproteins - physiology | Membrane Glycoproteins - antagonists & inhibitors | Immunoglobulin G - biosynthesis | Receptors, Antigen, T-Cell - immunology | Immunoglobulin epsilon-Chains - biosynthesis | Binding, Competitive - immunology | Interleukin-4 - physiology | Immunoglobulin Constant Regions - biosynthesis | Ki-1 Antigen - biosynthesis | Interleukin-4 - antagonists & inhibitors | Receptors, Antigen, T-Cell - metabolism | CD30 Ligand | Immunoglobulin epsilon-Chains - genetics | Ki-1 Antigen - metabolism | Protein Binding - immunology | Cell Differentiation - immunology | Immunoglobulin mu-Chains - genetics | PAX5 Transcription Factor | B-Lymphocyte Subsets - metabolism | Immunoglobulin gamma-Chains - biosynthesis | Up-Regulation - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 7 - metabolism | Ligands | CD40 Antigens - immunology | Positive Regulatory Domain I-Binding Factor 1 | T-Lymphocyte Subsets - immunology | Immunoglobulin gamma-Chains - genetics | Germinal Center - immunology | Immunoglobulin Class Switching - immunology | Receptors, OX40 | TNF Receptor-Associated Factor 2 | DNA-Binding Proteins - metabolism | CD40 Antigens - metabolism | Immunoglobulin Constant Regions - genetics | Palatine Tonsil - metabolism | B-Lymphocyte Subsets - immunology | Membrane Glycoproteins - immunology | Germinal Center - cytology | Recombination, Genetic - immunology | Receptors, Tumor Necrosis Factor - metabolism | Tumor Necrosis Factor Receptor Superfamily, Member 7 - immunology | Cell Line | Cells, Cultured | Immunophenotyping | Nuclear Proteins - metabolism | CD28 Antigens - immunology | Transcription Factors - genetics | Transcription Factors - metabolism | Germinal Center - metabolism | Proteins - metabolism | T-Lymphocyte Subsets - metabolism | Immunoglobulin D - biosynthesis | Immunoglobulin mu-Chains - biosynthesis | Immune Tolerance - genetics | Transcription, Genetic - immunology | CD40 Ligand | Promoter Regions, Genetic - immunology | Receptors, Tumor Necrosis Factor - immunology | Immunoglobulin M - biosynthesis | Plasma Cells - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article