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NATURE, ISSN 0028-0836, 07/2011, Volume 475, Issue 7354, pp. 110 - U133
High-dose intravenous immunoglobulin is a widely used therapeutic preparation of highly purified immunoglobulin G (IgG) antibodies. It is administered at high... 
IMMUNITY IN-VIVO | ALLERGIC INFLAMMATION | RESPONSES | ANTIINFLAMMATORY ACTIVITY | DC-SIGN | DENDRITIC CELL | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | TYPE-2 IMMUNITY | AUTOIMMUNE-DISEASE | Cell Adhesion Molecules - genetics | Dendritic Cells - immunology | Humans | Lectins, C-Type - immunology | Th2 Cells - immunology | Cell Adhesion Molecules - immunology | Lectins, C-Type - genetics | Th2 Cells - drug effects | Interleukins - metabolism | Receptors, IgG - metabolism | Immunoglobulins, Intravenous - metabolism | Lectins, C-Type - metabolism | Immunoglobulin G - immunology | Inflammation - drug therapy | Interleukins - immunology | Basophils - immunology | Arthritis - immunology | Immunoglobulin G - pharmacology | Interleukins - pharmacology | Bone Marrow | Autoimmune Diseases - drug therapy | Macrophages - immunology | Basophils - drug effects | Arthritis - pathology | Interleukin-33 | Immunoglobulin G - chemistry | Interleukin-4 - metabolism | Autoimmune Diseases - immunology | Crystallization | Receptors, Cell Surface - metabolism | Inflammation - immunology | Macrophages - cytology | Receptors, IgG - immunology | Cell Adhesion Molecules - metabolism | Immunoglobulins, Intravenous - pharmacology | Receptors, Cell Surface - immunology | Interleukin-4 - immunology | Animals | Arthritis - drug therapy | Ligands | Dendritic Cells - cytology | Immunoglobulins, Intravenous - chemistry | Mice | Basophils - metabolism | Immunoglobulins, Intravenous - immunology | Immunoglobulin G - metabolism | Receptors, Cell Surface - genetics
Journal Article
Science, ISSN 0036-8075, 4/2008, Volume 320, Issue 5874, pp. 373 - 376
It is well established that high doses of monomeric immunoglobulin G (IgG) purified from pooled human plasma [intravenous immunoglobulin (IVIG)] confer... 
Fc receptors | Polysaccharides | Immunoglobulins | Antiinflammatories | Lectins | Antibodies | Cytotoxicity | Recapitulation theory | Idiopathic thrombocytopenic purpura | Reports | Post hoc | OLIGOSACCHARIDES | SPECIFICITY | PROTECTION | MULTIDISCIPLINARY SCIENCES | SIALYLATION | RECEPTOR | GLYCOSYLATION | IMMUNOGLOBULIN-G | AUTOIMMUNE-DISEASE | BINDING | SIALYLTRANSFERASE | Recombinant Proteins - therapeutic use | Arthritis, Experimental - drug therapy | Immunoglobulin Fc Fragments - metabolism | Humans | Receptors, Fc - metabolism | Immunoglobulins, Intravenous - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Immunoglobulin Fc Fragments - administration & dosage | Purpura, Thrombocytopenic, Idiopathic - drug therapy | Polysaccharides - chemistry | Immunoglobulin Fc Fragments - therapeutic use | Autoimmune Diseases - drug therapy | Immunoglobulin G - chemistry | Mice, Inbred C57BL | Immunoglobulin G - therapeutic use | Recombinant Proteins - chemistry | Immunoglobulin Fc Fragments - chemistry | Glycosylation | Immunoglobulin G - administration & dosage | N-Acetylneuraminic Acid - chemistry | Galactose - chemistry | Animals | Immunoglobulins, Intravenous - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Mice, Inbred NOD | Immunoglobulins, Intravenous - chemistry | Mice | Carbohydrate Conformation | Immunoglobulin G - metabolism | Influence | Anti-inflammatory drugs | Properties | Recombinant molecules | Immunoglobulin G | Biochemistry | Immunology | Drug therapy | Autoimmune diseases | Immune system
Journal Article
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 09/2014, Volume 426, Issue 18, pp. 3166 - 3179
Journal Article
Molecules, ISSN 1420-3049, 09/2018, Volume 23, Issue 9, p. 2389
A previous study showed that intravenous immunoglobulin (IVIG) could preserve higher levels of biologically active lactone moieties of topotecan,... 
Intravenous immunoglobulin (IVIG) | Drug delivery | Camptothecin analogues (CPTs) | Protein-drug interaction | 7-ethyl-camptothecin | intravenous immunoglobulin (IVIG) | protein-drug interaction | HUMAN SERUM-ALBUMIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | camptothecin analogues (CPTs) | TOPOISOMERASE-I | MONOCLONAL-ANTIBODY | drug delivery | INFRARED-SPECTROSCOPY | CHEMISTRY, MULTIDISCIPLINARY | CONFORMATIONAL-CHANGES | CAMPTOTHECIN | MULTIDRUG-RESISTANCE | BREAST-CANCER RESISTANCE | EXPRESSION | ABCG2 | Camptothecin - metabolism | Temperature | Camptothecin - chemistry | Humans | Immunoglobulin G - chemistry | Molecular Conformation | Models, Molecular | Spectrometry, Fluorescence | Spectroscopy, Fourier Transform Infrared | Immunoglobulins, Intravenous - pharmacokinetics | Immunoglobulins, Intravenous - metabolism | Thermodynamics | Hydrogen Bonding | Hydrophobic and Hydrophilic Interactions | Protein Binding | Immunoglobulins, Intravenous - chemistry | Kinetics | Camptothecin - analogs & derivatives | Hydrogen-Ion Concentration | Immunoglobulin G - metabolism | Drugs | Camptothecin | Intravenous administration | Chemical engineering | Immunoglobulin G | Fluorescence | Systematic review | Hydrophobicity | Cancer therapies | Hydrogen bonding | Proteins | Aqueous solutions | Protein transport | Bonding | Binding | Antigens | Immunoglobulins | Topotecan | Chromophores | Equilibrium | Biological activity | Irinotecan | Human performance | Supramolecular compounds | Transporter | Cancer | Tumors
Journal Article
Blood, ISSN 0006-4971, 09/2010, Volume 116, Issue 10, pp. 1698 - 1704
Among various mechanisms for interactions with B cells, intravenous immunoglobulin (IVIg) may operate through the insertion of its Fc part into the Fc-gamma... 
ACTIVATED PROTEIN-KINASE | PHOSPHORYLATION | PATHWAY | CELL ANTIGEN RECEPTOR | NEGATIVE REGULATION | TOLERANCE | IN-VIVO | GROWTH | PROLIFERATION | INTRAVENOUS IMMUNOGLOBULINS | HEMATOLOGY | Apoptosis - drug effects | Humans | Receptors, Antigen, B-Cell - metabolism | Dose-Response Relationship, Drug | Immunoglobulins, Intravenous - metabolism | Flow Cytometry | Sialic Acid Binding Ig-like Lectin 2 - metabolism | Time Factors | Child | B-Lymphocytes - metabolism | Cell Survival - drug effects | B-Lymphocytes - cytology | Immunologic Factors - chemistry | Cells, Cultured | Enzyme Activation - drug effects | Immunoglobulins, Intravenous - pharmacology | Blotting, Western | N-Acetylneuraminic Acid - chemistry | B-Lymphocytes - drug effects | Microscopy, Confocal | Mitogen-Activated Protein Kinase 3 - metabolism | Signal Transduction - drug effects | Cell Line, Tumor | Protein Binding | Immunoglobulins, Intravenous - chemistry | Cell Cycle - drug effects | Immunologic Factors - metabolism | Immunologic Factors - pharmacology | Mitogen-Activated Protein Kinase 1 - metabolism | Immunologic Factors | Receptors, Antigen, B-Cell | B-Lymphocytes | Life Sciences | Immunology | Sialic Acid Binding Ig-like Lectin 2 | Signal Transduction | Cell Survival | N-Acetylneuraminic Acid | Cell Cycle | Enzyme Activation | Mitogen-Activated Protein Kinase 1 | Immunoglobulins, Intravenous | Mitogen-Activated Protein Kinase 3 | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e81448
Objectives: Although intravenous immunoglobulin (IVIG) is highly effective in Kawasaki disease (KD), mechanisms are not understood and 10-20% of patients are... 
B-LYMPHOCYTES | ANTIINFLAMMATORY ACTIVITY | P1 PROMOTER | GENE | BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE | DC-SIGN | MULTIDISCIPLINARY SCIENCES | GAMMA-GLOBULIN | IGG-FC | GLYCOSYLATION CHANGES | CD22 | Galactose - metabolism | Oligonucleotide Array Sequence Analysis | Fucose - metabolism | Humans | Child, Preschool | Male | RNA, Messenger - metabolism | Case-Control Studies | Female | Cell Line | B-Lymphocytes - enzymology | Mucocutaneous Lymph Node Syndrome - drug therapy | Enzyme-Linked Immunosorbent Assay | RNA, Messenger - genetics | Sialyltransferases - genetics | Solubility | Treatment Outcome | Glycosylation | N-Acetylneuraminic Acid - metabolism | N-Acetylneuraminic Acid - chemistry | RNA, Messenger - blood | Immunoglobulins, Intravenous - therapeutic use | Sialyltransferases - blood | Immunoglobulins, Intravenous - chemistry | Mucocutaneous Lymph Node Syndrome - enzymology | Enzymes | Polysaccharides | Kawasaki disease | Analysis | Immunoglobulin G | Aneurysms | Inflammation | Health aspects | Organic acids | Pediatrics | Animal models | Intravenous administration | Transcription | Aneurysm | Cardiovascular disease | Genomes | Blood | Training | Pretreatment | Enzyme-linked immunosorbent assay | Carbohydrates | Immunoglobulins | Medical treatment | Coronary artery | N-glycans | Blood levels | Polymerase chain reaction | Medicine | Hypotheses | Hospitals | Acids | Lymphocytes B | Coronary vessels | Cell lines | Mucocutaneous lymph node syndrome
Journal Article