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Cancer Cell, ISSN 1535-6108, 05/2017, Volume 31, Issue 5, pp. 711 - 723.e4
Effector T cells have the capability of recognizing and killing cancer cells. However, whether tumors can become immune resistant through exclusion of effector... 
T cell-inflamed tumor microenvironment | non-T cell-inflamed tumor microenvironment | immunotherapy resistance | immune escape | adoptive T cell transfer | METASTATIC MELANOMA | RESPONSES | IMMUNITY | MECHANISM | ONCOLOGY | CANCER REGRESSION | REJECTION | ANTIGENS | MICE | BLOCKADE | EXPRESSION | CELL BIOLOGY | Chemotaxis, Leukocyte | Tumor Escape | Basic-Leucine Zipper Transcription Factors - metabolism | Cell Proliferation | Dendritic Cells - immunology | Tumor Microenvironment | T-Lymphocytes - transplantation | Antigens, CD - metabolism | Repressor Proteins - deficiency | T-Lymphocytes - metabolism | Time Factors | Basic-Leucine Zipper Transcription Factors - deficiency | CD8-Positive T-Lymphocytes - metabolism | Dendritic Cells - metabolism | Repressor Proteins - metabolism | Melanoma - metabolism | Skin Neoplasms - pathology | Immunotherapy, Adoptive - methods | Signal Transduction | Skin Neoplasms - immunology | Skin Neoplasms - therapy | Repressor Proteins - genetics | Genotype | Integrin alpha Chains - metabolism | Basic-Leucine Zipper Transcription Factors - genetics | Melanoma - pathology | Tumor Burden | beta Catenin - metabolism | Mice, Knockout | Skin Neoplasms - metabolism | Phenotype | Animals | Melanoma - immunology | Chemokine CXCL9 - metabolism | Cell Line, Tumor | Immunologic Memory | T-Lymphocytes - immunology | CD8-Positive T-Lymphocytes - immunology | Melanoma - therapy | Chemokine CXCL10 - metabolism | Dendritic cells | T cells | Cancer | Immunotherapy | Adoptive T cell transfer
Journal Article
Annual Review of Immunology, ISSN 0732-0582, 2009, Volume 27, Issue 1, pp. 485 - 517
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 7, pp. 708 - 717
Journal Article
Annual Review of Immunology, ISSN 0732-0582, 2009, Volume 27, Issue 1, pp. 669 - 692
Journal Article
Cancer Cell, ISSN 1535-6108, 06/2012, Volume 21, Issue 6, pp. 822 - 835
Cancer-associated inflammation is thought to be a barrier to immune surveillance, particularly in pancreatic ductal adenocarcinoma (PDA). Gr-1 CD11b cells are... 
OVEREXPRESSION | MICROENVIRONMENT | ONCOLOGY | DUCTAL ADENOCARCINOMA | INTERLEUKIN-1-BETA | MICE | SUPPRESSOR-CELLS | INDUCTION | DIFFERENTIATION | MAMMARY CARCINOMAS | MOUSE MODELS | CELL BIOLOGY | Immunohistochemistry | Adenocarcinoma - pathology | CD8-Positive T-Lymphocytes - pathology | Pancreatic Neoplasms - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Humans | Carcinoma, Pancreatic Ductal - metabolism | Inflammation - metabolism | Adenocarcinoma - metabolism | RNA Interference | T-Lymphocytes - metabolism | Myeloid Cells - immunology | CD8-Positive T-Lymphocytes - metabolism | T-Lymphocytes - pathology | Carcinoma, Pancreatic Ductal - immunology | CD11b Antigen - immunology | Adenocarcinoma - immunology | Pancreatic Neoplasms - pathology | Receptors, Chemokine - metabolism | Mice, Transgenic | Inflammation - immunology | Receptors, Chemokine - immunology | Carcinoma, Pancreatic Ductal - pathology | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Tumor Microenvironment - immunology | Models, Immunological | Animals | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Pancreatic Neoplasms - immunology | Cell Line, Tumor | Myeloid Cells - metabolism | T-Lymphocytes - immunology | Mice | CD11b Antigen - metabolism | Myeloid Cells - pathology | CD8-Positive T-Lymphocytes - immunology | Medical colleges | Analysis | Pancreatic cancer | Oncology, Experimental | Genetically modified organisms | Inflammation | Macrophage colony stimulating factor | Research | T cells | Tumors | Cancer | granulocyte-macrophage colony stimulating factor | myeloid cells | T lymphocyte | carcinoma | pancreas
Journal Article
Annual Review of Immunology, ISSN 0732-0582, 4/2012, Volume 30, Issue 1, pp. 531 - 564
The immune system has evolved to mount an effective defense against pathogens and to minimize deleterious immune-mediated inflammation caused by commensal... 
immune homeostasis | autoimmunity | Foxp3 | tolerance | Autoimmunity | Tolerance | Immune homeostasis | TGF-BETA | INFECTIOUS TRANSPLANTATION TOLERANCE | TRANS-RETINOIC ACID | IMMUNOLOGY | CUTTING EDGE | THYMIC EPITHELIAL-CELLS | TRANSCRIPTION FACTOR FOXP3 | SPONTANEOUS AUTOIMMUNE ENCEPHALOMYELITIS | IMMUNOLOGICAL SELF-TOLERANCE | NF-KAPPA-B | BETA-MEDIATED INDUCTION | T-Lymphocytes, Regulatory - metabolism | Cytokines - metabolism | Receptors, Antigen, T-Cell - metabolism | Signal Transduction | Humans | Gene Expression Regulation | Homeostasis - immunology | Immune Tolerance | MicroRNAs - metabolism | Forkhead Transcription Factors - genetics | MicroRNAs - immunology | T-Lymphocytes, Regulatory - immunology | Animals | Forkhead Transcription Factors - metabolism | T-Lymphocytes, Regulatory - cytology | Protein Binding | Receptors, Antigen, T-Cell - immunology | Thymus Gland - immunology | Transcription, Genetic | Cell Differentiation | Enzyme Activation | Proto-Oncogene Proteins c-akt - metabolism | Thymus Gland - metabolism | Cytokines - immunology | Physiological aspects | Microorganisms | Inflammation | Immune response | Research | Health aspects | Pathogens | Transcription factors | Commensals | Immunoregulation | Hypersensitivity | Chronic infection | Autoantigens | Cell lineage | Lymphocytes T | Inflammatory diseases | Molecular modelling | Reviews | Foxp3 protein | Differentiation | Cancer | Immune system
Journal Article