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Gastroenterology, ISSN 0016-5085, 2011, Volume 140, Issue 1, pp. 221 - 230.e3
Background & Aims Anti–tumor necrosis factor (TNF)α antibodies are effective in treating patients with Crohn's disease whereas soluble TNFα receptors have not... 
Gastroenterology and Hepatology | Autoimmunity | IBD | Inflammatory Response | Type 2 Macrophage | MONOCLONAL-ANTIBODY | POLYMORPHISM | ACTIVE CROHNS-DISEASE | INFLAMMATORY-BOWEL-DISEASE | ACCENT-I | DOUBLE-BLIND | PLACEBO-CONTROLLED TRIAL | TNF-ALPHA | INFLIXIMAB | GASTROENTEROLOGY & HEPATOLOGY | T-LYMPHOCYTES | Cell Proliferation | Certolizumab Pegol | Humans | Lectins, C-Type - immunology | Anti-Inflammatory Agents - immunology | Caspase 3 - immunology | Antibodies, Monoclonal, Humanized | Lymphocyte Activation - immunology | Immunoglobulin Fc Fragments - immunology | Etanercept | Infliximab | Immunoglobulin G - immunology | T-Lymphocytes - drug effects | Leukocytes, Mononuclear - immunology | Tumor Necrosis Factor-alpha - immunology | Immunoglobulin G - pharmacology | Immunosuppressive Agents - pharmacology | Antibodies, Monoclonal - immunology | Macrophages - immunology | Cytokines - immunology | Polyethylene Glycols - pharmacology | Leukocytes, Mononuclear - drug effects | Anti-Inflammatory Agents - pharmacology | Cells, Cultured | Cytokines - secretion | Crohn Disease - immunology | Receptors, Cell Surface - immunology | Immunoglobulin Fab Fragments - pharmacology | Mannose-Binding Lectins - immunology | Receptors, Fc - immunology | Immunosuppressive Agents - immunology | Lymphocyte Activation - drug effects | Caspase 3 - analysis | T-Lymphocytes - immunology | Immunoglobulin Fab Fragments - immunology | Adalimumab | Receptors, Tumor Necrosis Factor - immunology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Apoptosis
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 12/2013, Volume 72, Issue 12, pp. 1947 - 1955
Background Immunogenicity of aTNFs is one of the mechanisms behind treatment failure. Objective To assess the effect of anti-drug antibodies (ADA) on drug... 
ALPHA MONOCLONAL-ANTIBODY | CONCOMITANT METHOTREXATE | CROHNS-DISEASE | Anti-TNF | ANKYLOSING-SPONDYLITIS | RHEUMATOLOGY | ANTITUMOR NECROSIS FACTOR | RHEUMATOID-ARTHRITIS PATIENTS | Autoimmune Diseases | ADALIMUMAB ANTIBODIES | EPISODIC TREATMENT | Methotrexate | LONG-TERM TREATMENT | CLINICAL-RESPONSE | Inflammatory Bowel Diseases - drug therapy | Methotrexate - pharmacology | Evidence-Based Medicine - methods | Antibodies, Monoclonal, Humanized - therapeutic use | Humans | Inflammatory Bowel Diseases - immunology | Antirheumatic Agents - immunology | Autoimmune Diseases - immunology | Anti-Inflammatory Agents, Non-Steroidal - immunology | Antibodies, Monoclonal - therapeutic use | Infliximab | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Antibody Formation - drug effects | Arthritis - drug therapy | Arthritis - immunology | Adalimumab | Antibodies, Monoclonal, Humanized - immunology | Immunosuppressive Agents - pharmacology | Antibodies, Monoclonal - immunology | Autoimmune Diseases - drug therapy | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Antirheumatic Agents - therapeutic use | Immunogenetics | Usage | Biological products | Tumor necrosis factor inhibitors | Influence | Research | Health aspects | Meta-analysis | Immunoglobulins | Clinical trials | Patients | Crohns disease | Studies | Inflammatory bowel disease | Immunotherapy | Measurement techniques | Tumor necrosis factor-TNF | Clinical medicine | Drug dosages
Journal Article
Nature Reviews Immunology, ISSN 1474-1733, 10/2011, Volume 11, Issue 10, pp. 702 - 711
Emerging evidence indicates that angiogenesis and immunosuppression frequently occur simultaneously in response to diverse stimuli. Here, we describe a... 
MYELOID SUPPRESSOR-CELLS | DENDRITIC CELLS | NK CELLS | INDOLEAMINE 2,3-DIOXYGENASE | REGULATORY T-CELLS | GENE-EXPRESSION | TUMOR ANGIOGENESIS | IMMUNOLOGY | MESENCHYMAL STEM-CELLS | OVARIAN-CARCINOMA | ENDOTHELIAL GROWTH-FACTOR | Myeloid Cells - cytology | Neoplasms - metabolism | T-Lymphocyte Subsets - immunology | Cell Communication - immunology | T-Lymphocyte Subsets - cytology | Humans | Neoplasm Proteins - immunology | Neoplasm Proteins - metabolism | Neovascularization, Pathologic - pathology | Intercellular Signaling Peptides and Proteins - metabolism | Neoplasm Proteins - secretion | Myeloid Cells - immunology | Immunosuppressive Agents - metabolism | Neovascularization, Pathologic - immunology | Cytokines - immunology | Cytokines - metabolism | Stromal Cells - metabolism | Homeostasis - immunology | Immune Tolerance | Stromal Cells - immunology | Tumor Microenvironment - immunology | Immunosuppression | Animals | Immunosuppressive Agents - immunology | Neoplasms - immunology | T-Lymphocyte Subsets - metabolism | Myeloid Cells - metabolism | Mice | Neovascularization, Pathologic - metabolism | Neoplasms - pathology | Intercellular Signaling Peptides and Proteins - immunology | Stromal Cells - cytology | Care and treatment | Immunotherapy | Physiological aspects | Research | Health aspects | Cancer | Endothelium | Angiogenesis | Reproduction | Inflammation | Injuries | Tumors
Journal Article
Blood, ISSN 0006-4971, 05/2014, Volume 123, Issue 19, pp. 3016 - 3026
Journal Article
Journal Article