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Immunological Reviews, ISSN 0105-2896, 03/2016, Volume 270, Issue 1, pp. 152 - 164
Summary Recombinant immunotoxins (RITs) are chimeric proteins designed to treat cancer. They are made up of an Fv or Fab that targets an antigen on a cancer... 
neutralizing antibodies | mesothelioma | immunotherapy | anti‐drug antibodies | mesothelin | Mesothelin | Mesothelioma | Anti-drug antibodies | Neutralizing antibodies | Immunotherapy | anti-drug antibodies | ADVANCED SOLID TUMORS | IMMUNOLOGY | EXOTOXIN-A MUTANTS | SURFACE-EXPOSED RESIDUES | B-CELL | PHASE-I TRIAL | REDUCED IMMUNOGENICITY | SITE-SPECIFIC MANNER | T-CELL EPITOPE | PSEUDOMONAS EXOTOXIN | HEMATOLOGIC MALIGNANCIES | Epitope Mapping | Sequence Deletion | Virulence Factors - genetics | Humans | Immunosuppressive Agents - therapeutic use | Immunotoxins - adverse effects | Epitopes, B-Lymphocyte - immunology | Virulence Factors - immunology | Recombinant Fusion Proteins | Antibodies, Neutralizing - immunology | Neoplasms - therapy | Immunotoxins - administration & dosage | Immunoglobulin Fragments - therapeutic use | Bacterial Toxins - genetics | Immunotoxins - chemistry | Epitopes, T-Lymphocyte - immunology | Drug Therapy, Combination | Immunosuppressive Agents - administration & dosage | ADP Ribose Transferases - chemistry | ADP Ribose Transferases - immunology | Drug Administration Routes | Immunotoxins - immunology | Antibodies, Monoclonal, Humanized - therapeutic use | Exotoxins - chemistry | Polyethylene Glycols | Bacterial Toxins - immunology | Exotoxins - immunology | Clinical Trials as Topic | Virulence Factors - chemistry | Bacterial Toxins - chemistry | ADP Ribose Transferases - genetics | Immunotoxins - genetics | Animals | Genetic Engineering | Immunoglobulin Fragments - immunology | Immunotoxins - therapeutic use | Neoplasms - immunology | Exotoxins - genetics | Antibody Formation | Antigens - immunology | Mice | Antibodies, Monoclonal, Humanized - immunology | Biological products | Antibody-toxin conjugates | Health aspects | Index Medicus
Journal Article
The FEBS Journal, ISSN 1742-464X, 12/2011, Volume 278, Issue 23, pp. 4683 - 4700
Journal Article
1994, 2nd ed., Target organ toxicology series, ISBN 0781702194, xxi, 761
Book
Immunopharmacology and immunotoxicology, ISSN 0892-3973, 1987
Journal
International Journal of Cancer, ISSN 0020-7136, 09/2014, Volume 135, Issue 6, pp. 1497 - 1508
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2012, Volume 109, Issue 29, pp. 11782 - 11787
Journal Article
2001, Methods in molecular biology, ISBN 0896037754, Volume 166, xi, 302
More potent and selective for killing cancer cells than chemotherapy, immunotoxins constitute a new class of human therapeutics that have widespread... 
Immunotoxins | Antibody-toxin conjugates | immunology | therapeutic use | Antibody-drug conjugates | Immunology | Biomedicine
Book