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2002, 1, Cellular and molecular mechanisms of toxin action, ISBN 6610102252, Volume 4, 288
Bacteria and plants produce powerful toxins that can cause a variety of diseases, some of which are lethal for many animal species. The mechanisms of action... 
Immunotoxins | Antitoxins | Toxins | Chimeric Proteins | Therapeutic use | pharmacology | Toxicology | Pharmacology | Cell Biology | Toxins-Therapeutic use
eBook
Drugs, ISSN 0012-6667, 11/2015, Volume 75, Issue 17, pp. 1993 - 2016
Through years of evolutionary selection pressures, organisms have developed potent toxins that coincidentally have marked antineoplastic activity. These... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | IMMUNOTOXIN RFB4(DSFV)-PE38 BL22 | PEGYLATED LIPOSOMAL DOXORUBICIN | EPOTHILONE-B ANALOG | DRUG-RESISTANT PHENOTYPE | GEMTUZUMAB OZOGAMICIN | PHASE-I TRIAL | METASTATIC BREAST-CANCER | ERIBULIN MESYLATE E7389 | PHARMACOLOGY & PHARMACY | TOXICOLOGY | ANTI-MESOTHELIN IMMUNOTOXIN | CHRONIC MYELOID-LEUKEMIA | Dioxoles - therapeutic use | Diphtheria Toxin - pharmacology | Recombinant Fusion Proteins - pharmacology | Furans - pharmacology | Humans | Recombinant Fusion Proteins - therapeutic use | Interleukin-2 - therapeutic use | Epothilones - pharmacology | Drug Discovery - methods | Antineoplastic Agents - therapeutic use | Biological Products - pharmacology | Epothilones - therapeutic use | Harringtonines - therapeutic use | Furans - therapeutic use | TOR Serine-Threonine Kinases - antagonists & inhibitors | Diphtheria Toxin - therapeutic use | Immunoconjugates - pharmacology | Cytochalasins - pharmacology | Dioxoles - pharmacology | Immunoconjugates - therapeutic use | Antineoplastic Agents - pharmacology | Ketones - therapeutic use | Cytochalasins - therapeutic use | Biological Products - therapeutic use | Ketones - pharmacology | Tetrahydroisoquinolines - pharmacology | Tetrahydroisoquinolines - therapeutic use | Withanolides - pharmacology | Harringtonines - pharmacology | Interleukin-2 - pharmacology | Withanolides - therapeutic use | Antimitotic agents | Care and treatment | Chemotherapy | Usage | Clinical trials | Dosage and administration | Diagnosis | Antineoplastic agents | Cancer | Index Medicus | Review
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2011, Volume 17, Issue 20, pp. 6389 - 6397
Journal Article
Immunological Reviews, ISSN 0105-2896, 03/2016, Volume 270, Issue 1, pp. 152 - 164
Summary Recombinant immunotoxins (RITs) are chimeric proteins designed to treat cancer. They are made up of an Fv or Fab that targets an antigen on a cancer... 
neutralizing antibodies | mesothelioma | immunotherapy | anti‐drug antibodies | mesothelin | Mesothelin | Mesothelioma | Anti-drug antibodies | Neutralizing antibodies | Immunotherapy | anti-drug antibodies | ADVANCED SOLID TUMORS | IMMUNOLOGY | EXOTOXIN-A MUTANTS | SURFACE-EXPOSED RESIDUES | B-CELL | PHASE-I TRIAL | REDUCED IMMUNOGENICITY | SITE-SPECIFIC MANNER | T-CELL EPITOPE | PSEUDOMONAS EXOTOXIN | HEMATOLOGIC MALIGNANCIES | Epitope Mapping | Sequence Deletion | Virulence Factors - genetics | Humans | Immunosuppressive Agents - therapeutic use | Immunotoxins - adverse effects | Epitopes, B-Lymphocyte - immunology | Virulence Factors - immunology | Recombinant Fusion Proteins | Antibodies, Neutralizing - immunology | Neoplasms - therapy | Immunotoxins - administration & dosage | Immunoglobulin Fragments - therapeutic use | Bacterial Toxins - genetics | Immunotoxins - chemistry | Epitopes, T-Lymphocyte - immunology | Drug Therapy, Combination | Immunosuppressive Agents - administration & dosage | ADP Ribose Transferases - chemistry | ADP Ribose Transferases - immunology | Drug Administration Routes | Immunotoxins - immunology | Antibodies, Monoclonal, Humanized - therapeutic use | Exotoxins - chemistry | Polyethylene Glycols | Bacterial Toxins - immunology | Exotoxins - immunology | Clinical Trials as Topic | Virulence Factors - chemistry | Bacterial Toxins - chemistry | ADP Ribose Transferases - genetics | Immunotoxins - genetics | Animals | Genetic Engineering | Immunoglobulin Fragments - immunology | Immunotoxins - therapeutic use | Neoplasms - immunology | Exotoxins - genetics | Antibody Formation | Antigens - immunology | Mice | Antibodies, Monoclonal, Humanized - immunology | Biological products | Antibody-toxin conjugates | Health aspects | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 05/2014, Volume 123, Issue 20, pp. 3128 - 3138
Journal Article
2005, ISBN 1588291995, xi, 311
Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin... 
Immunotoxins | pathology | Neurons | methods | Neurobiology | Drug targeting | metabolism | Antibodies, Monoclonal | Antibody-toxin conjugates | Therapeutic use | Neurotoxic agents | Cholinergic Fibers | Clinical & internal medicine | Medicine & Public Health | Neurosurgery
Book