UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.
Search Articles
1.
Full Text
Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes
Nature neuroscience, ISSN 1097-6256, 2019, Volume 22, Issue 7, pp. 1099 - 1109
d_article_not_yet_freely_accessible | Neuroscience(all) | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Lewy Bodies - ultrastructure | Lewy Bodies - chemistry | Parkinson Disease - pathology | Substantia Nigra - chemistry | Hippocampus - chemistry | Humans | Lewy Body Disease - pathology | Mesencephalon - chemistry | Alzheimer Disease - pathology | Intracellular Membranes - ultrastructure | Whole Exome Sequencing | Lewy Body Disease - metabolism | Microscopy, Confocal | Organelles - ultrastructure | alpha-Synuclein - analysis | Microscopy, Electron - methods | Substantia Nigra - ultrastructure | Alzheimer Disease - metabolism | Membrane Lipids - analysis | Hippocampus - ultrastructure | Parkinson Disease - metabolism | Imaging, Three-Dimensional | Microscopy, Fluorescence | Mesencephalon - ultrastructure | Causes of | Physiological aspects | Brain | Development and progression | Parkinson's disease | Neuroimaging | Raman spectra | Membranes | Fourier transforms | Pathogenesis | Parkinsons disease | Lipids | Inclusions | Synuclein | Coherent scattering | Proteins | Lipid membranes | Filaments | Etiology | Autopsy | Infrared imaging | Age | Image resolution | Medical imaging | Neurodegenerative diseases | Electron microscopy | Organelles | Lewy bodies | Neurological diseases | Pathology | Axons | Stimulated emission | Depletion | Microscopy | Index Medicus
Journal Article
Acta neuropathologica, ISSN 0001-6322, 2015, Volume 129, Issue 5, pp. 611 - 624
Autoimmunity | Pathology | Neurosciences | Medicine & Public Health | Amyloid deposits | Pathogenesis | Inclusion body myositis | Immune responses | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Muscles - immunology | Plaque, Amyloid - pathology | Humans | Middle Aged | Myositis, Inclusion Body - immunology | HLA Antigens - immunology | Inflammation - immunology | Muscles - pathology | Aging - pathology | Leukocytes - immunology | Myositis, Inclusion Body - pathology | Aged | Chemokines - immunology | Cytokines - immunology | Proteolysis | Myositis | Immunosuppressive agents | Index Medicus | Life Sciences | Immunology | Review
Journal Article
Acta neuropathologica, ISSN 0001-6322, 12/2011, Volume 122, Issue 6, pp. 691 - 702
C9 orf 72 | TDP43 | Pathology | Neurosciences | MND/ALS | Medicine & Public Health | FTLD | p62 | C9orf72 | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Frontotemporal Lobar Degeneration - pathology | Neurons - pathology | Pyramidal Cells - metabolism | DNA Repeat Expansion - genetics | Sequestosome-1 Protein | Humans | Middle Aged | Male | Case-Control Studies | DNA-Binding Proteins - metabolism | Aged, 80 and over | Adult | Female | C9orf72 Protein | Neurons - metabolism | Inclusion Bodies - metabolism | Purkinje Cells - metabolism | Amyotrophic Lateral Sclerosis - genetics | Cerebellum - metabolism | Hippocampus - pathology | DNA-Binding Proteins - genetics | Mutation - genetics | Cerebellum - pathology | Intranuclear Inclusion Bodies - pathology | DNA - genetics | Proteins - genetics | Hippocampus - metabolism | Amyotrophic Lateral Sclerosis - pathology | Adaptor Proteins, Signal Transducing - genetics | Inclusion Bodies - pathology | Pyramidal Cells - pathology | Aged | Frontotemporal Lobar Degeneration - genetics | Adaptor Proteins, Signal Transducing - metabolism | Purkinje Cells - pathology | Intranuclear Inclusion Bodies - metabolism | Ubiquitin | Brain | School facilities | Neurons | Amyotrophic lateral sclerosis | Universities and colleges | Education parks | Protein binding | Index Medicus | Cerebellum | Spinal cord | Motor neuron disease | Polymerase chain reaction | Neurodegeneration | Primers | Purkinje cells | Pyramidal cells | Inclusion bodies | Mutation | Hippocampus
Journal Article
4.
Full Text
Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies
Nature (London), ISSN 0028-0836, 05/2018, Volume 557, Issue 7706, pp. 558 - 563
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neurons - pathology | Oligodendroglia - metabolism | alpha-Synuclein - classification | Humans | Cytoplasm - metabolism | Male | Cytoplasm - pathology | Female | Neurons - metabolism | Lewy Bodies - metabolism | Lewy Bodies - pathology | Oligodendroglia - chemistry | Cytoplasm - chemistry | Lewy Bodies - chemistry | Neurons - chemistry | Mice, Inbred C57BL | Lewy Body Disease - pathology | Organ Specificity | Protein Folding | alpha-Synuclein - chemistry | Lewy Body Disease - metabolism | Oligodendroglia - pathology | Animals | Mice | alpha-Synuclein - metabolism | Parkinson's disease | Seeds | Neurodegenerative diseases | Neurons | Lewy body disease | Synuclein | Seeding | Lewy bodies | Atrophy | Pathology | Axons | Hypotheses | Neurodegeneration | Inclusion bodies | Oligodendrocytes | Dementia disorders | Intracellular | Alzheimers disease | Alzheimer's disease | Movement disorders | Dementia | Index Medicus
Journal Article
Acta neuropathologica, ISSN 0001-6322, 11/2009, Volume 118, Issue 5, pp. 617 - 627
Dendritic mRNA | Pick's disease | TDP-43 | FTD | FTLD | Frontotemporal lobar degeneration | Frontotemporal dementia | Pathology | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Inclusion Bodies - pathology | Frontotemporal Lobar Degeneration - pathology | RNA-Binding Protein FUS - metabolism | Frontotemporal Lobar Degeneration - metabolism | Inclusion Bodies - metabolism | Humans | Index Medicus
Journal Article
Brain (London, England : 1878), ISSN 0006-8950, 08/2015, Volume 138, Issue 8, pp. 2293 - 2309
Lewy body-like | inclusion bodies | multiple system atrophy | alpha-synuclein | neuropathology | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurons - pathology | Multiple System Atrophy - pathology | Humans | Middle Aged | Lewy Body Disease - pathology | Male | Lewy Body Disease - metabolism | Multiple System Atrophy - metabolism | Aged, 80 and over | Brain - pathology | Inclusion Bodies - pathology | Female | Neuroglia - metabolism | Aged | Neurons - metabolism | Inclusion Bodies - metabolism | alpha-Synuclein - metabolism | Index Medicus | Abridged Index Medicus | Original | 1060
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 04/2013, Volume 78, Issue 1, pp. 57 - 64
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | RNA, Small Interfering - genetics | Humans | Middle Aged | Male | Frontotemporal Dementia - metabolism | Neurons - ultrastructure | Muscular Dystrophies, Limb-Girdle - genetics | Adenosine Triphosphate - metabolism | Membrane Potential, Mitochondrial - genetics | Muscular Dystrophies, Limb-Girdle - pathology | NAD - metabolism | Fibroblasts - metabolism | Animals, Newborn | Frontotemporal Dementia - genetics | Magnesium - metabolism | Mitochondria - pathology | Fibroblasts - pathology | Mutation - genetics | Myositis, Inclusion Body - genetics | Osteitis Deformans - pathology | Muscular Dystrophies, Limb-Girdle - metabolism | Analysis of Variance | Luminescent Proteins - genetics | Adenosine Triphosphatases - genetics | Mice | Lipid Peroxidation - genetics | RNA, Small Interfering - metabolism | Valosin Containing Protein | Osteitis Deformans - metabolism | Family Health | Cerebral Cortex - cytology | Case-Control Studies | Osteitis Deformans - genetics | Transfection | Mitochondria - genetics | Cell Cycle Proteins - genetics | Myositis, Inclusion Body - pathology | Adult | Female | Neuroblastoma - pathology | Frontotemporal Dementia - pathology | Adenosine Triphosphatases - deficiency | Mice, Inbred C57BL | Cells, Cultured | Cell Cycle Proteins - deficiency | Mitochondria - metabolism | Animals | Oxygen Consumption - genetics | Myositis, Inclusion Body - metabolism | Aged | Nervous system diseases | Genes | Amyotrophic lateral sclerosis | Genetic aspects | Adenosine triphosphatase | Dementia | Proteins | Medical research | Phosphorylation | Biomedical research | Disease | Rodents | Respiration | Experiments | Patients | Index Medicus | Report
Journal Article
Cold Spring Harbor perspectives in medicine, ISSN 2157-1422, 2012, Volume 2, Issue 8, pp. a009258 - a009258
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Diagnosis, Differential | Parkinson Disease - pathology | Head Injuries, Closed - pathology | Supranuclear Palsy, Progressive - pathology | Multiple System Atrophy - pathology | Neuroglia - pathology | Humans | Nerve Degeneration - pathology | Parkinsonian Disorders - pathology | Brain - pathology | Inclusion Bodies - pathology | TDP-43 Proteinopathies - pathology | Lewy Bodies - pathology | Index Medicus | 071 | s
Journal Article