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Science, ISSN 0036-8075, 09/2016, Volume 353, Issue 6307, pp. 1553 - 1556
Journal Article
American journal of physiology. Gastrointestinal and liver physiology, ISSN 0193-1857, 11/2014, Volume 307, Issue 10, pp. G979 - G991
Enteroendocrine cells secrete over a dozen different hormones responsible for coordinating digestion, absorption, metabolism, and gut motility. Loss of... 
Islet1 | incretins | enteroendocrine | glucose regulation | PHYSIOLOGY | ENDOCRINE CELL-DEVELOPMENT | GASTROINTESTINAL-TRACT | FATE SPECIFICATION | ENTEROINSULAR AXIS | CONGENITAL MALABSORPTIVE DIARRHEA | CHROMOGRANIN-A | INCRETIN HORMONES | HOMEOBOX GENE ISL-1 | GLUCAGON-LIKE PEPTIDE-1 | RECEPTOR KNOCKOUT MICE | GASTROENTEROLOGY & HEPATOLOGY | Dietary Fats - metabolism | Intestinal Mucosa - metabolism | Gastric Inhibitory Polypeptide - metabolism | Age Factors | Intestine, Small - pathology | Transcription Factors - deficiency | Male | Malabsorption Syndromes - metabolism | Intestinal Absorption | Cholecystokinin - metabolism | LIM-Homeodomain Proteins - deficiency | Glucose Metabolism Disorders - metabolism | Female | Chromogranin A - metabolism | Enteroendocrine Cells - metabolism | Weight Gain | Microfilament Proteins - genetics | Somatostatin - metabolism | Animals, Newborn | Enteroendocrine Cells - pathology | Glucose Tolerance Test | Glucagon-Like Peptide 1 - metabolism | Mice, Inbred C57BL | Genotype | Biomarkers - blood | Transcription Factors - genetics | Gastrins - metabolism | Malabsorption Syndromes - genetics | Mice, Knockout | Ghrelin - metabolism | LIM-Homeodomain Proteins - genetics | Phenotype | Animals | Diarrhea - genetics | Glucose Metabolism Disorders - genetics | Serotonin - metabolism | Glucose Metabolism Disorders - blood | Diarrhea - metabolism | Intestine, Small - metabolism | Blood Glucose - metabolism | Integrases - genetics | Intestinal Mucosa - pathology | Glucose metabolism | Pancreatic beta cells | Cell research | Gene mutations | Homeostasis | Genetic research | Genetic aspects | Research | Health aspects | Hormones and Signaling
Journal Article
Diabetes, ISSN 0012-1797, 03/2018, Volume 67, Issue 3, pp. 385 - 399
The glucagon-like peptide 1 (GLP-1) receptor (GLP-1R) is a key target for type 2 diabetes (T2D) treatment. Because endocytic trafficking of agonist-bound... 
CLATHRIN-MEDIATED ENDOCYTOSIS | RETROMER | TRANSPORT | GLUCAGON-LIKE PEPTIDE-1 | GLUCOSE | MEMBRANE | INSULIN-SECRETION | ENDOCRINOLOGY & METABOLISM | PROTEIN-COUPLED RECEPTORS | EXPRESSION | BINDING | Sorting Nexins - genetics | Humans | Lysosomes - enzymology | Exenatide | Recombinant Fusion Proteins - metabolism | DNA-Binding Proteins - metabolism | Glucagon-Like Peptide-1 Receptor - genetics | Glucagon-Like Peptide-1 Receptor - metabolism | Insulin-Secreting Cells - metabolism | Lysosomes - metabolism | RNA Interference | Incretins - pharmacology | Sorting Nexins - metabolism | Cyclic AMP - metabolism | Insulin Secretion | Lysosomes - drug effects | Cell Line | Microscopy, Electron, Transmission | Second Messenger Systems - drug effects | DNA-Binding Proteins - antagonists & inhibitors | Tissue Culture Techniques | Endocytosis - drug effects | Recombinant Fusion Proteins - chemistry | DNA-Binding Proteins - genetics | Peptides - pharmacology | Lysosomes - ultrastructure | Insulin-Secreting Cells - ultrastructure | Insulin - metabolism | Animals | Insulin-Secreting Cells - drug effects | Calcium Signaling - drug effects | Mice | Sorting Nexins - antagonists & inhibitors | Venoms - pharmacology | Glucagon-Like Peptide-1 Receptor - agonists | Type 2 diabetes | Usage | Care and treatment | B cells | Research | Glucagon
Journal Article
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2010, Volume 54, Issue 6, pp. 1214 - 1223
Background & Aims Glucagon-like peptide-1 (GLP-1), a gut-derived peptide degraded by dipeptidyl peptidase-4 (DPP4), stimulates insulin secretion in response to... 
Gastroenterology and Hepatology | Incretins | Inflammatory cytokines | Liver | AMPK | Dipeptidylpetidase 4 | Lipogenesis | Glucagon-like peptide 1 | Gluconeogenesis | RAT-LIVER | METFORMIN | CELLS | HEPATOCYTES | INDUCED INSULIN-RESISTANCE | TISSUE GROWTH-FACTOR | GLUCOSE-METABOLISM | STEATOSIS | MICE | GASTROENTEROLOGY & HEPATOLOGY | AMP-Activated Protein Kinases - metabolism | Dipeptidyl Peptidase 4 - metabolism | Fatty Liver - pathology | Rats, Inbred F344 | Male | DNA Primers - genetics | Hepatocytes - metabolism | RNA, Messenger - metabolism | AMP-Activated Protein Kinases - deficiency | Liver - drug effects | Base Sequence | Lipids - blood | Inflammation Mediators - metabolism | Cyclic AMP - metabolism | Lipogenesis - physiology | Hepatocytes - drug effects | Fatty Liver - metabolism | Cytokines - metabolism | Glucagon-Like Peptide 1 - metabolism | Rats, Transgenic | Liver - metabolism | RNA, Messenger - genetics | Cells, Cultured | Glucagon-Like Peptide 1 - pharmacology | Rats | Dipeptidyl Peptidase 4 - genetics | Enzyme Activation - drug effects | Animals | Dipeptidyl Peptidase 4 - deficiency | Lipogenesis - drug effects | Metabolic Networks and Pathways - drug effects | AMP-Activated Protein Kinases - genetics | Fatty Liver - etiology | Phosphatases | Glucagon | Triglycerides | Glucose | Transforming growth factors | Fatty acids | Dextrose | Carnitine | Glucose metabolism | Angiotensin | Physiological aspects | Protein kinases | Protein binding
Journal Article
Journal Article
Journal Article
Diabetologia, ISSN 0012-186X, 2015, Volume 58, Issue 11, pp. 2637 - 2646
Journal Article
Journal Article
European Journal of Cell Biology, ISSN 0171-9335, 05/2017, Volume 96, Issue 3, pp. 240 - 253
The incretin hormones glucagon-like peptide (GLP)-1 and glucose-dependent insulinotropic polypeptide (GIP) are primarily known for their metabolic function in... 
Incretins | Alzheimer’s disease | Cell death | Microglia degeneration | Parkinson’s disease | Apoptosis |