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The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 12/2010, Volume 335, Issue 3, pp. 533 - 545
Journal Article
Free radical biology & medicine, ISSN 0891-5849, 12/2016, Volume 101, pp. 413 - 423
Leucine Rich Repeat Containing 8A (LRRC8A) is a required component of volume-regulated anion channels (VRACs). In vascular smooth muscle cells, tumor necrosis... 
c-Jun N-terminal kinase | Superoxide | Tumor necrosis factor-α | NADPH oxidase 1 | Leucine Rich Repeat Containing 8 | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | RNA, Small Interfering - genetics | Humans | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Receptors, Tumor Necrosis Factor, Type I - metabolism | Protein Subunits - metabolism | HEK293 Cells | Superoxides - metabolism | Vascular Cell Adhesion Molecule-1 - genetics | Membrane Proteins - metabolism | JNK Mitogen-Activated Protein Kinases - genetics | Phosphorylation - drug effects | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Protein Subunits - genetics | Cell Line | Superoxide Dismutase - pharmacology | Signal Transduction | Membrane Proteins - genetics | Endocytosis - drug effects | Gene Expression Regulation | NADPH Oxidase 1 - genetics | Cyclopentanes - pharmacology | Receptors, Tumor Necrosis Factor, Type I - genetics | Tumor Necrosis Factor-alpha - pharmacology | Membrane Proteins - antagonists & inhibitors | NF-kappa B - genetics | NADPH Oxidase 1 - metabolism | Vascular Cell Adhesion Molecule-1 - metabolism | Indans - pharmacology | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 11/2015, Volume 10, Issue 11, pp. e0141708 - e0141708
Inhibition of β-amyloid (Aβ) aggregation in the cerebral cortex of the brain is a promising therapeutic and defensive strategy in identification of disease... 
Plant Extracts - chemistry | Humans | Cholinesterase Inhibitors - chemistry | Chromatography, High Pressure Liquid | Spectroscopy, Fourier Transform Infrared | Tandem Mass Spectrometry | Plant Extracts - metabolism | Butyrylcholinesterase - chemistry | Cholinesterase Inhibitors - metabolism | Butyrylcholinesterase - metabolism | Amyloid beta-Peptides - metabolism | Acetone - chemistry | Indans - chemistry | Peptide Fragments - metabolism | Piperidines - chemistry | Protein Structure, Secondary | Piperidines - metabolism | Indans - metabolism | Alzheimer Disease - drug therapy | Acetylcholinesterase - chemistry | Microscopy, Confocal | Peptide Fragments - chemistry | Seaweed - metabolism | Protein Binding | Amyloid beta-Peptides - chemistry | Seaweed - chemistry | Acetylcholinesterase - metabolism | Amyloidogenesis | Brain | Oxidative stress | Biotechnology | Neurosciences | Fourier transforms | Cerebral cortex | Peptides | Laboratories | Neuropathology | Cognitive ability | Fluorescence | Confocal microscopy | Life assessment | Spectroscopic analysis | Agglomeration | Infrared analysis | Seaweeds | Molecular weight | Proteins | Oligomers | Metabolites | Bioactive compounds | Donepezil | Biocompatibility | Inhibition | Alzheimer's disease | Algae | Fibrils | Disaggregation | Biological activity | Cholinesterase | Chromatography | Neurological diseases | Studies | Pathology | Brain research | Microscopy | Natural products | β-Amyloid | Drug discovery | Alzheimers disease | Column chromatography | Binding sites | Scanning microscopy | Acetone | Index Medicus
Journal Article
Psychopharmacology, ISSN 0033-3158, 1/2015, Volume 232, Issue 1, pp. 305 - 314
The novel opioid receptor antagonist, GSK1421498, has been shown to attenuate reward-driven compulsive behaviours, such as stimulant drug seeking or binge... 
μ-Opioid receptor | GSK1521498 | Neurosciences | Biomedicine | Pharmacology/Toxicology | Psychiatry | Inverse agonism | Pharmacology & Pharmacy | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Naltrexone - analogs & derivatives | Naltrexone - therapeutic use | Cricetulus | Humans | Analgesics, Opioid - pharmacology | Male | Indans - therapeutic use | Compulsive Behavior - metabolism | Naltrexone - pharmacology | Narcotic Antagonists - metabolism | Compulsive Behavior - drug therapy | HEK293 Cells | CHO Cells | Naltrexone - metabolism | Triazoles - therapeutic use | Cricetinae | Naloxone - metabolism | Morphine - pharmacology | Receptors, Opioid, mu - metabolism | Indans - metabolism | Morphine - metabolism | Analgesics, Opioid - therapeutic use | Naloxone - therapeutic use | Treatment Outcome | Receptors, Opioid, mu - antagonists & inhibitors | Triazoles - pharmacology | Triazoles - metabolism | Guanosine 5'-O-(3-Thiotriphosphate) - metabolism | Animals | Narcotic Antagonists - therapeutic use | Naloxone - pharmacology | Narcotic Antagonists - pharmacology | Ligands | Mice | Analgesics, Opioid - metabolism | Reward | Morphine - therapeutic use | Indans - pharmacology | Protein Binding - physiology | Care and treatment | Compulsive eating | Morphine | Dosage and administration | Pharmacology | Research | Diagnosis | Narcotics | Antagonist drugs | Psychopharmacology | Index Medicus | Original Investigation
Journal Article
Stem cells (Dayton, Ohio), ISSN 1066-5099, 03/2012, Volume 30, Issue 3, pp. 548 - 560
Defining the signaling mechanisms that regulate the fate of adult stem cells is an essential step toward their use in regenerative medicine. Platelet‐derived... 
Marrow stromal stem cells | Adult stem cells | Multipotential differentiation | Mesenchymal stem cells | Cell & Tissue Engineering | Life Sciences & Biomedicine | Hematology | Oncology | Biotechnology & Applied Microbiology | Science & Technology | Cell Biology | Gene Expression - drug effects | Cell Nucleus Size - drug effects | Homeodomain Proteins - metabolism | Humans | Male | Janus Kinases - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Quinolines - pharmacology | Gene Knockdown Techniques | Octamer Transcription Factor-3 - genetics | Young Adult | Receptor, Epidermal Growth Factor - metabolism | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | RNA Interference | Receptor, Platelet-Derived Growth Factor alpha - antagonists & inhibitors | Adult | Female | MAP Kinase Kinase Kinases - antagonists & inhibitors | Mesenchymal Stromal Cells - physiology | STAT3 Transcription Factor - metabolism | Pyrazoles - pharmacology | Receptor, Platelet-Derived Growth Factor beta - metabolism | Mesenchymal Stromal Cells - drug effects | Proto-Oncogene Proteins c-abl - genetics | Nanog Homeobox Protein | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Signal Transduction | Cells, Cultured | MAP Kinase Kinase Kinases - metabolism | Actomyosin - metabolism | Homeodomain Proteins - genetics | Cell Shape - drug effects | Janus Kinases - antagonists & inhibitors | Cell Differentiation - drug effects | Receptor, Platelet-Derived Growth Factor alpha - genetics | Octamer Transcription Factor-3 - metabolism | Proto-Oncogene Proteins c-abl - metabolism | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | Cell Nucleus - drug effects | Indans - pharmacology | Proteins | Medical research | Rodents | Stem cells | Index Medicus | Tissue-Specific Stem Cells | Original Research
Journal Article
Journal of medicinal chemistry, ISSN 0022-2623, 11/2013, Volume 56, Issue 22, pp. 9089 - 9099
Journal Article
BMC plant biology, ISSN 1471-2229, 2012, Volume 12, Issue 1, pp. 128 - 128
Background: Jasmonic acid (JA) is a well-characterized signaling molecule in plant defense responses. However, its relationships with other signal molecules in... 
Medicinal herb | Endophytic fungi | Atractylodes lancea | Volatile oil | Jasmonic acid | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Masoprocol - pharmacology | Oils, Volatile - analysis | Salicylic Acid - metabolism | Antioxidants - metabolism | Oxylipins - antagonists & inhibitors | Plant Diseases - microbiology | Nitric Oxide - analysis | Atractylodes - drug effects | Time Factors | Fungi - physiology | Endophytes | Free Radical Scavengers - analysis | Oils, Volatile - metabolism | Salicylic Acid - analysis | Atractylodes - physiology | Free Radical Scavengers - metabolism | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | Cyclopentanes - antagonists & inhibitors | Cyclopentanes - pharmacology | Oils, Volatile - isolation & purification | Onium Compounds - pharmacology | Atractylodes - chemistry | Hydrogen Peroxide - metabolism | Catalase - metabolism | Triazoles - pharmacology | Oxylipins - metabolism | Organophosphonates - pharmacology | Signal Transduction - drug effects | Hydrogen Peroxide - analysis | Oxylipins - pharmacology | Benzoates - pharmacology | Cyclopentanes - metabolism | Signal Transduction - physiology | Salicylic Acid - antagonists & inhibitors | Nitric Oxide - metabolism | Plants, Medicinal | Indans - pharmacology | Medicinal plants | Defense industry | Metabolites | Nitric oxide | Medicine, Botanic | Ibuprofen | Medicine, Herbal | Cellular signal transduction | Petroleum industry | Atractylodes | Jasmonates | Fungi | Studies | Hydrogen peroxide | Acids | Petroleum production | Life sciences | Biosynthesis | Index Medicus
Journal Article
Journal Article
Respiratory research, ISSN 1465-9921, 03/2012, Volume 13, Issue 1, pp. 28 - 28
Background: Small airway narrowing is an important pathology which impacts lung function in chronic obstructive pulmonary disease (COPD). The accumulation of... 
PDE4 | Fibrosis | Indacaterol | Lung fibroblasts | Beta-2 agonist | Roflumilast | Anti-inflammatory | Life Sciences & Biomedicine | Respiratory System | Science & Technology | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Humans | Actins - metabolism | Quinolones - pharmacology | Lung - cytology | Adrenergic beta-2 Receptor Agonists - pharmacology | Inflammation - metabolism | Benzamides - pharmacology | Chemokine CCL5 - metabolism | Lung - metabolism | Pulmonary Fibrosis - metabolism | Transforming Growth Factor beta1 - pharmacology | Cyclopropanes - pharmacology | Fibroblasts - metabolism | Endothelin-1 - metabolism | Cells, Cultured | Phosphodiesterase 4 Inhibitors - pharmacology | Fibronectins - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Aminopyridines - pharmacology | Fibroblasts - drug effects | Lung - drug effects | Pulmonary Fibrosis - prevention & control | Fibroblasts - cytology | Inflammation - prevention & control | Chemokine CXCL10 - metabolism | Connective Tissue Growth Factor - metabolism | Indans - pharmacology | Adrenergic beta agonists | Physiological aspects | Fibroblasts | Research | Fibronectins | Lung diseases, Obstructive | Endothelin | Cytokines | RNA | Inflammation | Transforming growth factors | Muscle proteins | Homeopathy | Materia medica and therapeutics | Therapeutics | Protein kinases | Protein binding | Cell culture | Airway management | Lungs | Ligands | Smooth muscle | Kinases | Binding sites | Manuscripts | Chemokines | Index Medicus
Journal Article
Journal Article