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British Journal of Pharmacology, ISSN 0007-1188, 2015, Volume 172, Issue 1, pp. 24 - 37
Background and Purpose N-docosahexaenoylethanolamine (DHEA) is the ethanolamine conjugate of the long-chain polyunsaturated n-3 fatty acid docosahexaenoic... 
PLASMA | CONCISE GUIDE | NITRIC-OXIDE SYNTHASE | INFLAMMATION | OXYGENATION | ANANDAMIDE | PHARMACOLOGY & PHARMACY | FATTY-ACIDS | FISH-OIL | KAPPA-B | ETHANOLAMIDE | Endocannabinoids - metabolism | Bornanes - pharmacology | Male | NF-kappa B - metabolism | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | PPAR gamma - metabolism | Piperidines - pharmacology | Thiazolidinediones - pharmacology | Pyrazoles - pharmacology | Cell Line | Indenes - pharmacology | Cyclooxygenase 2 Inhibitors - pharmacology | Dehydroepiandrosterone - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Toll-Like Receptor 3 - metabolism | Toll-Like Receptor 4 - metabolism | Arachidonic Acids - pharmacology | Mice, Knockout | Dinoprostone - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Macrophages - metabolism | Animals | PPAR gamma - antagonists & inhibitors | Interferon-beta - metabolism | Anilides - pharmacology | Cyclooxygenase 2 - metabolism | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Mice | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Nitric Oxide - metabolism | Myeloid Differentiation Factor 88 - metabolism | Androgens | Dehydroepiandrosterone | DNA microarrays | Anti-inflammatory drugs | RNA | Ethanolamines | Macrophages | Gene expression | Fatty acids | Medical research | Rodents | Research Papers | arrive guidelines | pharmacology | fatty-acids | cannabinoid receptor | prostaglandin e-2 | nitric-oxide synthase | anandamide | fish-oil | concise guide | kappa-b
Journal Article
Life Sciences, ISSN 0024-3205, 02/2014, Volume 97, Issue 1, pp. 55 - 63
Journal Article
Nature, ISSN 0028-0836, 03/2010, Volume 464, Issue 7287, pp. 431 - 435
Activating mutations in KRAS and BRAF are found in more than 30% of all human tumours and 40% of melanoma, respectively, thus targeting this pathway could have... 
SELECTIVE INHIBITOR | POTENT | EFFICACY | MECHANISM | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | KINASE | C-RAF | B-RAF | MUTATIONS | PROTEINS | Neoplasms - metabolism | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Diphenylamine - pharmacology | raf Kinases - antagonists & inhibitors | Humans | Protein Multimerization | ras Proteins - metabolism | Protein Transport - drug effects | Extracellular Signal-Regulated MAP Kinases - metabolism | raf Kinases - metabolism | Diphenylamine - analogs & derivatives | Mitogen-Activated Protein Kinase Kinases - metabolism | Adenosine Triphosphate - metabolism | Indoles - pharmacology | Benzamides - pharmacology | Cell Membrane - metabolism | raf Kinases - genetics | Cell Membrane - drug effects | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins B-raf - chemistry | Pyrazoles - pharmacology | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Cell Line | Indenes - pharmacology | raf Kinases - chemistry | Proto-Oncogene Proteins c-raf - genetics | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Neoplasms - enzymology | Proto-Oncogene Proteins - genetics | Enzyme Activation - drug effects | Sulfonamides - pharmacology | Proto-Oncogene Proteins c-raf - metabolism | Neoplasms - drug therapy | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | MAP Kinase Signaling System - drug effects | Protein Kinase Inhibitors - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Proto-Oncogene Proteins c-raf - deficiency | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Neoplasms - pathology | Ras genes | Growth | Physiological aspects | Cellular signal transduction | Genetic aspects | Research | Mitogen-activated protein kinases | Competition | Clinical trials | Enzymes | Kinases | Proteins | Cellular | Inhibitors | Pathways | Tumours | Signalling | Dimerization
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 12/2016, Volume 24, Issue 23, pp. 6119 - 6130
Journal Article
Life Sciences, ISSN 0024-3205, 2005, Volume 76, Issue 13, pp. 1439 - 1453
Journal Article
The Plant Cell, ISSN 1040-4651, 10/2014, Volume 26, Issue 10, pp. 3964 - 3983
Jasmonic acid and its derivatives Gasmonates [JAs]) play central roles in floral development and maturation. The binding of jasmonoyl-l-isoleucine (JA-IIe) to... 
Transcriptional regulatory elements | RESEARCH ARTICLES | Flowering | Nectaries | Gene expression regulation | Biosynthesis | Plants | Flowers | Corolla | Genotypes | Plant cells | BHLH TRANSCRIPTION FACTOR | ARABIDOPSIS-THALIANA | DEFENSE RESPONSES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALLENE OXIDE CYCLASE | POLLINATOR ATTRACTION | ACID BIOSYNTHESIS | PLANT SCIENCES | CELL BIOLOGY | FLOWER DEVELOPMENT | CHALCONE SYNTHASE | GENE-EXPRESSION | PLANT-METABOLISM | Oligonucleotide Array Sequence Analysis | Flowers - metabolism | Methyltransferases - metabolism | Indenes - metabolism | Methyltransferases - genetics | Gene Expression Profiling | Amino Acids - pharmacology | Arabidopsis Proteins - metabolism | Amino Acids - metabolism | Isoleucine - pharmacology | RNA Interference | Plant Nectar - metabolism | Plants, Genetically Modified | Abscisic Acid - metabolism | Plant Proteins - metabolism | Manduca - physiology | Indenes - pharmacology | Acetone - analogs & derivatives | Arabidopsis Proteins - genetics | Tobacco - metabolism | Acetates - metabolism | Tobacco - drug effects | Esterases - metabolism | Acetone - metabolism | Cyclopentanes - pharmacology | Esterases - genetics | Reverse Transcriptase Polymerase Chain Reaction | Isoleucine - metabolism | Pollination | Abscisic Acid - pharmacology | Oxylipins - metabolism | Plant Proteins - genetics | Gene Expression Regulation, Plant - drug effects | Animals | Metabolic Networks and Pathways | Isoleucine - analogs & derivatives | Models, Biological | Tobacco - genetics | Oxylipins - pharmacology | Cyclopentanes - metabolism | Acetates - pharmacology | Flowers - drug effects | Plant Growth Regulators - metabolism | Flowers - genetics | Plant Growth Regulators - pharmacology | Physiological aspects | Amino acids | Genetic engineering | Instrument industry
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2016, Volume 24, Issue 22, pp. 5873 - 5883
A facile stereoselective synthesis of novel dispiro indeno pyrrolidine/pyrrolothiazole–thiochroman hybrids has been achieved by 1,3-dipolar cycloaddition of... 
1,3-Dipolar cycloaddition | M. tuberculosis H37Rv | AchE inhibition | Azomethine ylides | Dispiro heterocycles | CCRF-CEM | M. tuberculosis H | M. tuberculosis HRv | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXPEDIENT SYNTHESIS | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | POTENT INHIBITORS | HIGHLY FUNCTIONALIZED DISPIROPYRROLIDINES | PYRROLIDINE | HUMAN STEROID SULFATASE | REGIOSELECTIVE SYNTHESIS | 3-COMPONENT | DERIVATIVES | Stereoisomerism | Antineoplastic Agents - chemical synthesis | Humans | Cholinesterase Inhibitors - chemistry | Cholinesterase Inhibitors - chemical synthesis | Structure-Activity Relationship | Indenes - chemistry | Mycobacterium tuberculosis - drug effects | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Anti-Bacterial Agents - chemistry | Antineoplastic Agents - pharmacology | Molecular Structure | Chromones - pharmacology | Spiro Compounds - chemistry | Cell Survival - drug effects | Indenes - pharmacology | Models, Molecular | Antineoplastic Agents - chemistry | Pyrrolidines - chemistry | Anti-Bacterial Agents - chemical synthesis | Chromones - chemistry | Cholinesterase Inhibitors - pharmacology | Cell Line, Tumor | Thiazoles - chemistry | Anti-Bacterial Agents - pharmacology | Cell Proliferation - drug effects | Thiazoles - pharmacology | Acetylcholinesterase - metabolism | Spiro Compounds - pharmacology | Drug Screening Assays, Antitumor | Care and treatment | Analysis | Cancer
Journal Article
Experimental Neurology, ISSN 0014-4886, 11/2016, Volume 285, Issue Pt A, pp. 82 - 95
Journal Article