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1. Full Text Somatostatin receptor-based imaging and therapy of gastroenteropancreatic neuroendocrine tumors
by Kwekkeboom, Dik J and Kam, Boen L and van Essen, Martijn and Teunissen, Jaap J M and van Eijck, Casper H J and Valkema, Roelf and de Jong, Marion and de Herder, Wouter W and Krenning, Eric P
Endocrine-related cancer, ISSN 1351-0088, 3/2010, Volume 17, Issue 1, pp. R53 - R73
Review | Oncology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Humans | Digestive System Neoplasms - radiotherapy | Antineoplastic Agents - therapeutic use | Yttrium Radioisotopes - pharmacokinetics | Octreotide - pharmacokinetics | Digestive System Neoplasms - drug therapy | Gallium Radioisotopes - therapeutic use | Digestive System Neoplasms - diagnostic imaging | Neuroendocrine Tumors - diagnostic imaging | Receptors, Somatostatin - analysis | Organometallic Compounds - therapeutic use | Yttrium Radioisotopes - therapeutic use | Somatostatin - analogs & derivatives | Radiopharmaceuticals - pharmacokinetics | Octreotide - analogs & derivatives | Organometallic Compounds - pharmacokinetics | Treatment Outcome | Clinical Trials as Topic | Combined Modality Therapy | Indium Radioisotopes - pharmacokinetics | Positron-Emission Tomography - methods | Octreotide - therapeutic use | Somatostatin - pharmacokinetics | Peptides, Cyclic - pharmacokinetics | Neuroendocrine Tumors - radiotherapy | Animals | Organotechnetium Compounds - pharmacokinetics | Positron-Emission Tomography - standards | Receptors, Somatostatin - drug effects | Gallium Radioisotopes - pharmacokinetics | Neuroendocrine Tumors - drug therapy | Peptides, Cyclic - therapeutic use | Quality of Life | Indium Radioisotopes - therapeutic use | Somatostatin - therapeutic use | Radiopharmaceuticals - therapeutic use | Index Medicus
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2. Full Text Evaluation of a 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-conjugated bombesin-based radioantagonist for the labeling with single-photon emission computed tomography, positron emission tomography, and therapeutic radionuclides
by Mansi, Rosalba and Wang, Xuejuan and Forrer, Flavio and Kneifel, Stefan and Tamma, Maria-Luisa and Waser, Beatrice and Cescato, Renzo and Reubi, Jean Claude and Maecke, Helmut R
Clinical cancer research, ISSN 1078-0432, 08/2009, Volume 15, Issue 16, pp. 5240 - 5249
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Neoplasms - metabolism | Receptors, Bombesin - agonists | Radioisotopes - pharmacokinetics | Tomography, Emission-Computed, Single-Photon - methods | Receptors, G-Protein-Coupled - metabolism | Humans | Transplantation, Heterologous | Receptors, G-Protein-Coupled - agonists | Gallium Radioisotopes - therapeutic use | Heterocyclic Compounds, 1-Ring - chemistry | Female | Bombesin - chemistry | Oligopeptides - chemistry | Radioisotopes - therapeutic use | Oligopeptides - pharmacokinetics | Cells, Cultured | Indium Radioisotopes - chemistry | Gallium Radioisotopes - chemistry | Indium Radioisotopes - pharmacokinetics | Positron-Emission Tomography - methods | Neoplasms - diagnostic imaging | Receptors, Bombesin - antagonists & inhibitors | Receptors, Bombesin - metabolism | Animals | Mice, Nude | Models, Biological | Receptors, G-Protein-Coupled - antagonists & inhibitors | Gallium Radioisotopes - pharmacokinetics | Indium Radioisotopes - therapeutic use | Mice | Drug Delivery Systems - methods | Radioisotopes - chemistry | Index Medicus
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3. Full Text Effects of anti-VEGF on pharmacokinetics, biodistribution, and tumor penetration of trastuzumab in a preclinical breast cancer model
by Pastuskovas, Cinthia V and Mundo, Eduardo E and Williams, Simon P and Nayak, Tapan K and Ho, Jason and Ulufatu, Sheila and Clark, Suzanna and Ross, Sarajane and Cheng, Eric and Parsons-Reponte, Kathryn and Cain, Gary and Van Hoy, Marjie and Majidy, Nicholas and Bheddah, Sheila and Chuh, Josefa Dela Cruz and Kozak, Katherine R and Lewin-Koh, Nicholas and Nauka, Peter and Bumbaca, Daniela and Sliwkowski, Mark and Tibbitts, Jay and Theil, Frank-Peter and Fielder, Paul J and Khawli, Leslie A and Boswell, C. Andrew
Molecular cancer therapeutics, ISSN 1535-7163, 03/2012, Volume 11, Issue 3, pp. 752 - 762
Life Sciences & Biomedicine | Oncology | Science & Technology | Immunohistochemistry | Humans | Receptor, ErbB-2 - metabolism | Antibody Affinity - immunology | Tomography, X-Ray Computed | Positron-Emission Tomography | Vascular Endothelial Growth Factor A - metabolism | Breast Neoplasms - metabolism | Dose-Response Relationship, Drug | Tissue Distribution | Multimodal Imaging | Antibody Specificity - immunology | Antibodies, Monoclonal, Humanized - pharmacokinetics | Female | Receptor, ErbB-2 - immunology | Antibodies, Monoclonal - immunology | Antibodies, Monoclonal - pharmacology | Indium Radioisotopes - chemistry | Vascular Endothelial Growth Factor A - immunology | Indium Radioisotopes - pharmacokinetics | Iodine Radioisotopes - pharmacokinetics | Breast Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - pathology | Mice, Nude | Cell Line, Tumor | Iodine Radioisotopes - chemistry | Mice | Trastuzumab | Antibodies, Monoclonal, Humanized - chemistry | Index Medicus
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4. Full Text Radiometal-labeled anti-VCAM-1 nanobodies as molecular tracers for atherosclerosis – impact of radiochemistry on pharmacokinetics
by Bala, Gezim and Crauwels, Maxine and Blykers, Anneleen and Remory, Isabel and Marschall, Andrea L.J and Dübel, Stefan and Dumas, Laurent and Broisat, Alexis and Martin, Charlotte and Ballet, Steven and Cosyns, Bernard and Caveliers, Vicky and Devoogdt, Nick and Xavier, Catarina and Hernot, Sophie
Biological chemistry, ISSN 1431-6730, 02/2019, Volume 400, Issue 3, pp. 323 - 332
VCAM-1 knock-down mice | mass effect | single-domain antibody fragment | specific activity | molecular imaging | vulnerable plaque | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Vascular Cell Adhesion Molecule-1 - immunology | Single-Domain Antibodies - metabolism | Mice, Inbred C57BL | Molecular Imaging | Mice, Knockout | Single-Domain Antibodies - immunology | Animals | Atherosclerosis - diagnostic imaging | Single-Domain Antibodies - chemistry | Gallium Radioisotopes | Isotope Labeling | Mice | Indium Radioisotopes | Phenotypes | Vascular cell adhesion molecule 1 | Radiolabelling | Organs | Radioisotopes | Pharmacology | Intrabodies | Mimicry | Proteins | Apolipoprotein E | Arteriosclerosis | Atherosclerosis | Radiochemistry | Chelation | In vivo methods and tests | Lesions | Pharmacokinetics | Tracers | Index Medicus
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5. Full Text Pharmacokinetics and Biodistribution of 111In- and 177Lu-Labeled J591 Antibody Specific for Prostate-Specific Membrane Antigen: Prediction of 90Y-J591 Radiation Dosimetry Based on 111In or 177Lu?
by Vallabhajosula, Shankar and Kuji, Ichei and Hamacher, Klaus A and Konishi, Shota and Kostakoglu, Lale and Kothari, Paresh A and Milowski, Mathew I and Nanus, David M and Bander, Neil H and Goldsmith, Stanley J
The Journal of nuclear medicine (1978), ISSN 0161-5505, 04/2005, Volume 46, Issue 4, pp. 634 - 641
Lu-labeled J591 monoclonal antibody | Y dosimetry | Antiprostate-specific membrane antigen antibody | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - radiotherapy | Radioisotopes - pharmacokinetics | Humans | Middle Aged | Half-Life | Antibodies, Monoclonal - therapeutic use | Male | Metabolic Clearance Rate | Yttrium Radioisotopes - pharmacokinetics | Tissue Distribution | Aged, 80 and over | Lutetium - therapeutic use | Radiometry - methods | Yttrium Radioisotopes - therapeutic use | Lutetium - pharmacokinetics | Radiotherapy Dosage | Radioisotopes - therapeutic use | Radiopharmaceuticals - pharmacokinetics | Antibodies, Monoclonal - pharmacokinetics | Body Burden | Indium Radioisotopes - pharmacokinetics | Organ Specificity | Indium Radioisotopes - therapeutic use | Aged | Prostate-Specific Antigen - immunology | Relative Biological Effectiveness | Radiopharmaceuticals - therapeutic use | Index Medicus
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6. Full Text Synthesis, biodistribution and excretion of radiolabeled poly(2-alkyl-2-oxazoline)s
by Gaertner, Florian C and Luxenhofer, Robert and Blechert, Birgit and Jordan, Rainer and Essler, Markus
Journal of controlled release, ISSN 0168-3659, 2007, Volume 119, Issue 3, pp. 291 - 300
DOTA | Biocompatibility | Poly(2-oxazoline) | Biodistribution | 111In | Pharmacology & Pharmacy | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Pharmaceutical technology. Pharmaceutical industry | Biological and medical sciences | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Chitin - pharmacokinetics | Biological Availability | Metabolic Clearance Rate | Antineoplastic Agents - administration & dosage | Polyamines | Drug Carriers - chemistry | Oxazoles - chemistry | Tissue Distribution | Chitin - analogs & derivatives | Heterocyclic Compounds, 1-Ring - chemistry | Female | Chitin - chemical synthesis | Radiopharmaceuticals - chemistry | Radiopharmaceuticals - pharmacokinetics | Polymers - chemical synthesis | Indium Radioisotopes - chemistry | Oxazoles - pharmacokinetics | Solubility | Chitin - chemistry | Drug Carriers - chemical synthesis | Indium Radioisotopes - pharmacokinetics | Mice, Inbred Strains | Oxazoles - chemical synthesis | Animals | Polymers - pharmacokinetics | Indium Radioisotopes - therapeutic use | Polymers - chemistry | Drug Carriers - pharmacokinetics | Mice | Radiopharmaceuticals - therapeutic use | Index Medicus
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7. Full Text Tumor Targeting with Antibody-Functionalized, Radiolabeled Carbon Nanotubes
by McDevitt, Michael R and Chattopadhyay, Debjit and Kappel, Barry J and Jaggi, Jaspreet Singh and Schiffman, Scott R and Antczak, Christophe and Njardarson, Jon T and Brentjens, Renier and Scheinberg, David A
The Journal of nuclear medicine (1978), ISSN 0161-5505, 07/2007, Volume 48, Issue 7, pp. 1180 - 1189
DOTA | Rituximab | Single-walled carbon nanotubes | Nanotechnology | Nanoconstructs | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Neoplasm Transplantation | Humans | Transplantation, Heterologous | Heterocyclic Compounds, 1-Ring - chemistry | Female | Antibodies, Monoclonal - chemistry | Antibodies, Neoplasm - immunology | Lymphoma, B-Cell - metabolism | Antibodies, Monoclonal, Murine-Derived | Radiopharmaceuticals - chemistry | Radiopharmaceuticals - pharmacokinetics | Chelating Agents - chemistry | Indium Radioisotopes - chemistry | Solubility | Antibodies, Monoclonal - pharmacokinetics | Indium Radioisotopes - pharmacokinetics | Mice, SCID | Radiopharmaceuticals - administration & dosage | Animals | Nanotubes, Carbon | Antibodies, Monoclonal - administration & dosage | Indium Radioisotopes - administration & dosage | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Infrared radiation | Cells | Nanotubes | Cancer | Index Medicus
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8. Full Text Dual SPECT imaging of 111 In and 67 Ga to simultaneously determine in vivo the pharmacokinetics of different radiopharmaceuticals: A quantitative tool in pre-clinical research
by Esquinas, Pedro L and Rodríguez-Rodríguez, Cristina and Esposito, Tullio V. F and Harboe, Jeppe and Bergamo, Marta and Celler, Anna and Saatchi, Katayoun and Sossi, Vesna and Häfeli, Urs O
Physics in medicine & biology, ISSN 0031-9155, 12/2018, Volume 63, Issue 23, p. 235029
Ga-67 | dual-isotope imaging | In-111 | In vivo preclinical studies | Multi-pinhole SPECT | Tomography, Emission-Computed, Single-Photon - methods | Animals | Radiopharmaceuticals - pharmacokinetics | Humans | Gallium Radioisotopes - pharmacokinetics | Image Processing, Computer-Assisted - methods | Indium Radioisotopes - pharmacokinetics | Phantoms, Imaging
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9. Full Text Quantitative cumulative biodistribution of antibodies in mice
: Effect of modulating binding affinity to the neonatal Fc receptor
by Yip, Victor and Palma, Enzo and Tesar, Devin B and Mundo, Eduardo E and Bumbaca, Daniela and Torres, Elizabeth K and Reyes, Noe A and Shen, Ben Q and Fielder, Paul J and Prabhu, Saileta and Khawli, Leslie A and Boswell, C Andrew
mAbs, ISSN 1942-0862, 05/2014, Volume 6, Issue 3, pp. 689 - 696
FcRn | pharmacokinetics | indium | biodistribution | metabolism | radiolabeled | Indium | Metabolism | Pharmacokinetics | Biodistribution | Radiolabeled | Animals, Newborn | Cricetinae | Cricetulus | Humans | Receptors, Fc - metabolism | Indium Radioisotopes - pharmacokinetics | Iodine Radioisotopes - pharmacokinetics | Immunoglobulin G - administration & dosage | Antibodies, Monoclonal, Humanized - genetics | Genetic Variation | Tissue Distribution | Iodine Radioisotopes - administration & dosage | Animals | Antibodies, Monoclonal, Humanized - administration & dosage | Immunoglobulin G - genetics | Antibodies, Monoclonal, Humanized - pharmacokinetics | Indium Radioisotopes - administration & dosage | Proteolysis | Female | Receptors, Fc - genetics | Mice | CHO Cells | Immunoglobulin G - metabolism | Index Medicus | Report
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10. Full Text Comprehensive evaluation of a somatostatin-based radiolabelled antagonist for diagnostic imaging and radionuclide therapy
by Wang, Xuejuan and Fani, Melpomeni and Schulz, Stefan and Rivier, Jean and Reubi, Jean Claude and Maecke, Helmut R
European journal of nuclear medicine and molecular imaging, ISSN 1619-7070, 12/2012, Volume 39, Issue 12, pp. 1876 - 1885
Medicine & Public Health | Orthopedics | Imaging | Oncology | Radionuclide therapy | Nuclear Medicine | Somatostatin | Antagonist | Imaging / Radiology | Cardiology | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Neoplasm Transplantation | Humans | Octreotide - pharmacokinetics | Tissue Distribution | Radiopharmaceuticals - metabolism | HEK293 Cells | Organometallic Compounds - therapeutic use | Female | Neoplasms - radiotherapy | Receptors, Somatostatin - antagonists & inhibitors | Receptors, Somatostatin - metabolism | Indium Radioisotopes - metabolism | Lutetium - therapeutic use | Lutetium - pharmacokinetics | Radiopharmaceuticals - pharmacokinetics | Organometallic Compounds - pharmacokinetics | Indium Radioisotopes - pharmacokinetics | Neoplasms - diagnostic imaging | Octreotide - therapeutic use | Octreotide - metabolism | Animals | Organometallic Compounds - metabolism | Mice, Nude | Radionuclide Imaging | Indium Radioisotopes - therapeutic use | Mice | Radiopharmaceuticals - therapeutic use | Lutetium - metabolism | Nuclear medicine | Pharmacology | Medical imaging | Radiation therapy | Peptides | Cancer | Index Medicus | Cell culture | Animal models | Sucrose | Radioisotopes | Data processing | imaging | Kidney | Lysine | Xenografts | Pharmacokinetics | Somatostatin receptors | Tumors
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11. Full Text EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer
by Song, Lei and Falzone, Nadia and Vallis, Katherine A
International journal of radiation biology, ISSN 0955-3002, 11/2016, Volume 92, Issue 11, pp. 716 - 723
EGF | targeted radiotherapy | Auger electron emitters | Gold nanoparticles | Indium-111 | Index Medicus | Space life sciences | s
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12. Full Text Preclinical animal research on therapy dosimetry with dual isotopes
by Konijnenberg, Mark and Jong, Marion
European journal of nuclear medicine and molecular imaging, ISSN 1619-7070, 05/2011, Volume 38, Issue SUPPL. 1, pp. 19 - 27
Radionuclide therapy | Dose-effect models | Radiation dosimetry | Medicine & Public Health | Orthopedics | Oncology | Nuclear Medicine | Imaging / Radiology | Cardiology | Dose–effect models | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Lutetium - pharmacokinetics | Radiotherapy Dosage | Drug Evaluation, Preclinical - methods | Radioisotopes - pharmacokinetics | Radioisotopes - therapeutic use | Rats | Yttrium Radioisotopes - pharmacokinetics | Indium Radioisotopes - pharmacokinetics | Radiation Dosage | Lutetium - administration & dosage | Yttrium Radioisotopes - administration & dosage | Animals | Indium Radioisotopes - administration & dosage | Radioisotopes - administration & dosage | Indium Radioisotopes - therapeutic use | Neoplasms - radiotherapy | Lutetium - therapeutic use | Radiometry - methods | Dose-Response Relationship, Radiation | Yttrium Radioisotopes - therapeutic use | Radiopharmaceuticals - therapeutic use | Peptides | Radiation | Tumors | Nuclear medicine | Radiation therapy | Laboratory animals | Isotopes | Index Medicus | Review
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13. Full Text Radiolabeled Monoclonal Antibodies Specific to the Extracellular Domain of Prostate-Specific Membrane Antigen: Preclinical Studies in Nude Mice Bearing LNCaP Human Prostate Tumor
by Smith-Jones, Peter M and Vallabhajosula, Shankar and Navarro, Vincent and Bastidas, Diego and Goldsmith, Stanley J and Bander, Neil H
The Journal of nuclear medicine (1978), ISSN 0161-5505, 04/2003, Volume 44, Issue 4, pp. 610 - 617
Monoclonal antibody | In-DOTA-huJ591 | I- huJ591 | Prostate-specific membrane antigen | Tumor localization | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Biological and medical sciences | Medical sciences | Neoplasm Transplantation | Prostatic Neoplasms - metabolism | Injections, Intravenous | Humans | Male | Metabolic Clearance Rate | Reference Values | Antibodies, Monoclonal - blood | Tissue Distribution | Iodine Radioisotopes - blood | Sensitivity and Specificity | Prostatic Neoplasms - diagnostic imaging | Tumor Cells, Cultured | Reproducibility of Results | Radiopharmaceuticals - pharmacokinetics | Antibodies, Monoclonal - pharmacokinetics | Indium Radioisotopes - pharmacokinetics | Iodine Radioisotopes - pharmacokinetics | Organ Specificity | Radiopharmaceuticals - blood | Radiography | Radiopharmaceuticals - administration & dosage | Iodine Radioisotopes - administration & dosage | Isotope Labeling - methods | Animals | Antibodies, Monoclonal - administration & dosage | Indium Radioisotopes - administration & dosage | Indium Radioisotopes - blood | Mice, Nude | Carboxypeptidases - metabolism | Antigens, Surface | Mice | Mice, Inbred BALB C | Glutamate Carboxypeptidase II | Index Medicus
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