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Reproductive Sciences, ISSN 1933-7191, 2019, p. 193371911983378
Journal Article
Analytical Biochemistry, ISSN 0003-2697, 09/2018, Volume 556, pp. 85 - 90
Journal Article
Molecular Medicine Reports, ISSN 1791-2997, 04/2018, Volume 17, Issue 4, pp. 4867 - 4873
Indoleamine 2, 3-dioxygenase (IDO) catalyzes the initial and rate-limiting step in the degradation pathway of the essential amino acid tryptophan and is... 
Indoleamine 2 | Kynurenine | Tryptophan | Immune regulation | 3-dioxygenase | Regulatory T cell | MEDICINE, RESEARCH & EXPERIMENTAL | ALLOGRAFT-REJECTION | DENDRITIC CELLS | TOLERANCE | kynurenine | regulatory T cell | 2,3-DIOXYGENASE EXPRESSION | CANCER | immune regulation | TRYPTOPHAN CATABOLISM | indoleamine 2 | ONCOLOGY | IDO | INFECTION | MICE | tryptophan | T-CELLS
Journal Article
Science Translational Medicine, ISSN 1946-6234, 05/2010, Volume 2, Issue 32, pp. 32ra36 - ra36
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 126, Issue 4, pp. 754 - 762.e1
Journal Article
International Journal of Medical Sciences, ISSN 1449-1907, 09/2017, Volume 14, Issue 12, pp. 1181 - 1188
Upregulation of connexin 43 (Cx43) showed potential in enhancing immune surveillance that was suppressed in the tumor microenvironment. The expression of... 
Indoleamine 2 | 3-dioxygenase 1 | Salmonella | Connexin 43 | Resveratrol | CHEMOSENSITIVITY | DENDRITIC CELLS | TUMOR | CANCER | indoleamine 2 | MEDICINE, GENERAL & INTERNAL | MELANOMA | connexin 43 | ATTENUATED SALMONELLA | resveratrol | UP-REGULATION | 2,3-DIOXYGENASE | T-CELLS
Journal Article
Journal of Drug Targeting, ISSN 1061-186X, 08/2019, Volume 27, Issue 7, pp. 724 - 731
Immune escape plays an important hallmark of cancer. The tryptophan-catabolizing enzyme indoleamine 2, 3-dioxygenase 1 (IDO1) is involved in the immune escape... 
indoleamine 2 | kynurenine pathway | inhibitor screening methods | IDO1 inhibitor | fluorescence detection | Immune escape | 3-dioxygenase
Journal Article
by Yang, D and Li, TQ and Li, YL and Zhang, SN and Li, WR and Liang, H and Xing, ZK and Du, LS and He, JC and Kuang, CX and Yang, Q
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, ISSN 1756-9966, 02/2019, Volume 38, Issue 1, pp. 1 - 15
Journal Article
Current Cancer Drug Targets, ISSN 1568-0096, 11/2016, Volume 16, Issue 9, pp. 755 - 764
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2015, Volume 10, Issue 2, pp. e0118562 - e0118562
Dendritic cells (DC) interact with naive T cells to regulate the delicate balance between immunity and tolerance required to maintain immunological... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | IN-VITRO | NOD MICE | INHIBITION | ARYL-HYDROCARBON RECEPTOR | NONOBESE DIABETIC MICE | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | 2,3-DIOXYGENASE | TRYPTOPHAN CATABOLISM | Indoleamine-Pyrrole 2,3,-Dioxygenase - biosynthesis | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Signal Transduction | Monocytes - cytology | Vaccines, Subunit - genetics | Dendritic Cells - immunology | Humans | Monocytes - metabolism | NF-kappa B - metabolism | Proinsulin - genetics | Proteome | Gene Expression Profiling | Vaccines, Subunit - immunology | Cholera Toxin - genetics | Proteomics | Cholera Toxin - immunology | Cell Differentiation | Dendritic Cells - cytology | Dendritic Cells - metabolism | Cluster Analysis | Proinsulin - immunology | Autoimmunity | Enzymes | Dendritic cells | Type 1 diabetes | Vaccination | Physiological aspects | Tryptophan | Protein biosynthesis | Cholera | Vaccines | Cholera toxin | T cells | Disease | Mucosa | Bar codes | Hydrocarbons | Biochemistry | Immunity | Proteins | Hyperglycemia | Inhibition | Fusion protein | Public health | Cholera toxin B subunit | NF-κB protein | Dioxygenase | Antigens | Cytokines | Toxin b | Insulin | Immunological tolerance | Immunosuppression | Protein synthesis | Water-borne diseases | Homeostasis | Lymphocytes T | Diabetes mellitus (insulin dependent) | Infections | Biosynthesis | Kinases | Inoculation | Immunology | Lymphocytes | Pancreas | Immune system | Degradation products | Maturation | Therapeutic applications | Diabetes mellitus | Inflammation | Pharmacology | Medicine | Monocytes | Diabetes | Autoimmune diseases | Dendritic structure | Health disparities | Index Medicus
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2019, Volume 179, pp. 38 - 55
Indoleamine 2, 3-dioxygenase 1 (IDO1) plays a key role in tryptophan catabolism which is an important mechanism in immune tolerance. The small molecule... 
Indoleamine 2,3-dioxygenase | Oxadiazole | Life span | PD-1 | Immunotherapy | CHEMISTRY, MEDICINAL | STAGE-III | POTENT INHIBITORS | CANCER | DISCOVERY | CHALLENGES | IMIDAZOLEISOINDOLE DERIVATIVES | PEMBROLIZUMAB | 2,3-DIOXYGENASE | CELL | Viral antibodies | Amines | Analysis | Tryptophan | Antibodies | Chemical properties
Journal Article