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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2008, Volume 105, Issue 44, pp. 17073 - 17078
Topical application of phorbol myristate acetate (PMA) elicits intense local inflammation that facilitates outgrowth of premalignant lesions in skin after... 
T lymphocytes | Dendritic cells | Noise reduction | Papilloma | Cultured cells | Inflammation | Mice | Lesions | Tumors | Cancer | Tryptophan | TPA | T cells | Carcinogenesis | TOLERANCE | MULTIDISCIPLINARY SCIENCES | LIGATION | CANCER | TRYPTOPHAN CATABOLISM | PLASMACYTOID DENDRITIC CELLS | dendritic cells | carcinogenesis | IDO | REGULATORY T-CELLS | RESISTANCE | 2,3-DIOXYGENASE | EXPRESSION | tryptophan | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Lymph Nodes - pathology | Tetradecanoylphorbol Acetate - pharmacology | Dendritic Cells - immunology | Lymph Nodes - enzymology | Signal Transduction - immunology | Dermatitis, Contact - immunology | T-Lymphocytes - metabolism | Immune Tolerance - immunology | Models, Animal | Papilloma - pathology | Dermatitis, Contact - enzymology | Skin Neoplasms - pathology | Dermatitis, Contact - pathology | Skin Neoplasms - immunology | Mice, Inbred C57BL | Lymph Nodes - immunology | Disease Progression | Animals | Dendritic Cells - enzymology | Papilloma - immunology | T-Lymphocytes - immunology | Dendritic Cells - cytology | Oxidases | Complications and side effects | Amines | Research | Health aspects | Proteins | Signal transduction | Lymphatic system | Rodents | Gene expression | Cells | Index Medicus | Biological Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 2, pp. e14698 - e14698
The kynurenine pathway (KP) of tryptophan metabolism is linked to antimicrobial activity and modulation of immune responses but its role in stem cell biology... 
L-TRYPTOPHAN TRANSPORT | IMMUNE-RESPONSE | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | 2,3-DIOXYGENASE ACTIVITY | DENDRITIC CELLS | MULTIPLE-SCLEROSIS | MULTIDISCIPLINARY SCIENCES | CD4(+) T-CELLS | CEREBROSPINAL-FLUID | NEURAL PRECURSOR CELLS | MARROW STROMAL CELLS | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Mesenchymal Stromal Cells - enzymology | Gene Expression Regulation, Enzymologic - drug effects | Humans | Male | Interferon-beta - physiology | RNA - genetics | Cell Differentiation - genetics | Adult | Kynurenine - metabolism | Mesenchymal Stromal Cells - physiology | RNA - metabolism | Mesenchymal Stromal Cells - drug effects | Mice, Inbred C57BL | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Enzyme Activation - drug effects | Metabolic Networks and Pathways - genetics | Animals | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Mice | Metabolic Networks and Pathways - drug effects | Interferon-gamma - pharmacology | Cell proliferation | Multiple sclerosis | Senescence | Antimicrobial activity | Transcription | Mesenchyme | Stem cell transplantation | Infections | Activation | Neurogenesis | Biomedical materials | Cell growth | Allografts | Metabolites | Modulation | Bone marrow | Biocompatibility | Physiology | Dioxygenase | Medical research | Enzymes | Immune response | Hematology | Tryptophan | Cell division | Metabolism | Brain research | Hospitals | γ-Interferon | Stem cells | Neural stem cells | Interferon | Differentiation | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, pp. e66546 - e66546
Influenza infection stimulates protective host immune responses but paradoxically enhances lung indoleamine 2,3 dioxygenase (IDO) activity, an enzyme that... 
PLASMACYTOID DENDRITIC CELLS | TRYPTOPHAN | KYNURENINE | IDO | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | SUPPRESSION | SELECTION | 2,3-DIOXYGENASE | EXPRESSION | T-CELLS | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | T-Lymphocyte Subsets - immunology | Mediastinum | Interferons - immunology | Orthomyxoviridae Infections - enzymology | Enzyme Activation - immunology | Lung - enzymology | Orthomyxoviridae Infections - genetics | CD4-Positive T-Lymphocytes - immunology | Lymph Nodes - enzymology | Th17 Cells - metabolism | CD8-Positive T-Lymphocytes - metabolism | Influenza A virus - immunology | CD4-Positive T-Lymphocytes - virology | Disease Models, Animal | Signal Transduction | Lymph Nodes - immunology | Mice, Knockout | Animals | T-Lymphocyte Subsets - metabolism | Interferons - metabolism | Th17 Cells - immunology | Immunologic Memory | Mice | CD8-Positive T-Lymphocytes - immunology | Lung - immunology | Orthomyxoviridae Infections - immunology | Enzymes | T cells | Health aspects | Immunotherapy | Influenza | Veterinary colleges | Animal models | CD8 antigen | Lung | Immune clearance | Effector cells | Viruses | Lymphocytes T | Infections | Veterinary medicine | Recovery | Lymph nodes | Streptococcus infections | T-cell receptor | Immunology | Lymphocytes | Rodents | Animal tissues | Bone marrow | Foxp3 protein | Drug dosages | Dioxygenase | Immunological memory | Memory cells | Immune response | Cloning | Inflammation | Pharmacology | Ablation | Morbidity | Hemopoiesis | CD4 antigen | Drainage | Signaling | Infectious diseases | Lungs | γ-Interferon | Interferon | Regulation | Viral infections | Cancer | Index Medicus
Journal Article
Science, ISSN 0036-8075, 2014, Volume 343, Issue 6175, pp. 1118 - 1118
Journal Article
Immunity, ISSN 1074-7613, 08/2013, Volume 39, Issue 2, pp. 372 - 385
Endogenous tryptophan (Trp) metabolites have an important role in mammalian gut immune homeostasis, yet the potential contribution of Trp metabolites from... 
INTESTINAL INFLAMMATION | LACTOBACILLUS-PLANTARUM | CANDIDA-ALBICANS | GASTROINTESTINAL-TRACT | GUT | REGULATORY T-CELLS | MICE | COLONIZATION | JOHNSONII STRAIN NCC533 | INNATE LYMPHOID-CELLS | IMMUNOLOGY | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Lactobacillus reuteri - metabolism | Receptors, Aryl Hydrocarbon - deficiency | Toll-Like Receptor 2 - genetics | Tryptophan - chemistry | Indoleamine-Pyrrole 2,3,-Dioxygenase - deficiency | Lactobacillus reuteri - immunology | Tryptophan - metabolism | Interleukins - metabolism | Gastrointestinal Tract - immunology | Toll-Like Receptor 2 - deficiency | Indoles - metabolism | Receptors, Aryl Hydrocarbon - metabolism | Female | Candidiasis - immunology | Basic Helix-Loop-Helix Transcription Factors - deficiency | Basic Helix-Loop-Helix Transcription Factors - genetics | Mice, Inbred C57BL | Myeloid Differentiation Factor 88 - genetics | Receptors, Aryl Hydrocarbon - genetics | Gastrointestinal Tract - microbiology | Interleukin-17 - genetics | Interleukin-17 - deficiency | Candida albicans - immunology | Mice, SCID | Gastrointestinal Tract - metabolism | Mice, Inbred C3H | Mice, Knockout | Probiotics | Animals | Myeloid Differentiation Factor 88 - deficiency | Energy Metabolism | Lactobacillus reuteri - growth & development | Mice | Mice, Inbred BALB C | Metagenome | Tryptophan | Metabolites | Interleukins | Aldehydes | Medical research | Stomach | Colleges & universities | Homeostasis | Ligands | Software | Infections | Metabolism | Experiments | Index Medicus
Journal Article
International Journal of Cancer, ISSN 0020-7136, 01/2012, Volume 130, Issue 1, pp. 96 - 104
Journal Article
Journal of Neuroinflammation, ISSN 1742-2094, 08/2010, Volume 7, Issue 1, pp. 43 - 43
Journal Article
Journal Article