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Chemical Research in Toxicology, ISSN 0893-228X, 09/2008, Volume 21, Issue 9, pp. 1814 - 1822
In vitro covalent binding assessments of drugs have been useful in providing retrospective insights into the association between drug metabolism and a... 
ACYL GLUCURONIDES | CHEMISTRY, MEDICINAL | PROTEIN | RAT | REACTIVE METABOLITES | TIENILIC ACID | HEPATIC-NECROSIS | BIOACTIVATION | IDENTIFICATION | CHEMISTRY, MULTIDISCIPLINARY | MASS-SPECTROMETRY | TOXICOLOGY | HUMAN URINE | Buspirone - chemistry | Raloxifene Hydrochloride - pharmacology | Thiazoles - metabolism | Acetaminophen - metabolism | Humans | Microsomes, Liver - metabolism | Indomethacin - metabolism | Simvastatin - pharmacology | Diclofenac - chemistry | Thiazines - metabolism | Propranolol - pharmacology | Toxicity Tests - methods | Binding Sites | Simvastatin - metabolism | Microsomes, Liver - chemistry | Indomethacin - pharmacology | Paroxetine - metabolism | Raloxifene Hydrochloride - metabolism | Triazoles - metabolism | Ticrynafen - metabolism | Paroxetine - pharmacology | Diclofenac - metabolism | Paroxetine - chemistry | Diphenhydramine - pharmacology | Diclofenac - pharmacology | Triazoles - chemistry | Buspirone - metabolism | Ticrynafen - pharmacology | Structure-Activity Relationship | Buspirone - pharmacology | Hepatocytes - metabolism | Dose-Response Relationship, Drug | Carbamazepine - chemistry | Diphenhydramine - metabolism | Acetaminophen - pharmacology | Microsomes, Liver - drug effects | Propranolol - metabolism | Carbamazepine - metabolism | Thiazines - pharmacology | Molecular Structure | Drug Evaluation, Preclinical | Hepatocytes - drug effects | Carbamazepine - pharmacology | Simvastatin - chemistry | Acetaminophen - chemistry | Ticrynafen - chemistry | Propranolol - chemistry | Diphenhydramine - chemistry | Thiazines - chemistry | Triazoles - pharmacology | Indomethacin - chemistry | Thiazoles - chemistry | Thiazoles - pharmacology | Raloxifene Hydrochloride - chemistry | Index Medicus
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 01/2012, Volume 80, Issue 1, pp. 46 - 53
A new delivery system based on drug cyclodextrin (Cd) complexation and loading into nanostructured lipid carriers (NLC) has been developed to improve... 
Nanostructured lipid carriers (NLC) | Polymeric cyclodextrins | Hydrogel | Topical formulation | Ketoprofen | VIVO | NLC | NANOPARTICLES SLN | TRANSDERMAL DELIVERY | COMPLEXES | INDOMETHACIN | SOLID-STATE | IN-VITRO | BETA-CYCLODEXTRIN | PHARMACOLOGY & PHARMACY | NAPROXEN | Polymers - administration & dosage | Chemistry, Pharmaceutical - methods | Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry | Drug Carriers - administration & dosage | Delayed-Action Preparations - chemistry | Drug Carriers - chemistry | Delayed-Action Preparations - administration & dosage | Ketoprofen - chemistry | Lipids - chemistry | Hydrogel, Polyethylene Glycol Dimethacrylate - administration & dosage | Cyclodextrins - chemistry | Epichlorohydrin - administration & dosage | Polysaccharides, Bacterial - chemistry | Polysaccharides, Bacterial - administration & dosage | Freeze Drying - methods | Drug Stability | Solubility | Ketoprofen - administration & dosage | Lipids - administration & dosage | Permeability | Particle Size | Epichlorohydrin - chemistry | beta-Cyclodextrins - administration & dosage | beta-Cyclodextrins - chemistry | Nanostructures - administration & dosage | Cyclodextrins - administration & dosage | Nanostructures - chemistry | Polymers - chemistry | Administration, Topical | Cyclodextrins | Dextrins | Transdermal medication | Index Medicus
Journal Article
Journal Article
Environmental Science and Pollution Research, ISSN 0944-1344, 5/2010, Volume 17, Issue 4, pp. 898 - 907
The occurrence and fate of pharmaceuticals in the aquatic environment is recognized as one of the emerging issues in environmental chemistry and as a matter of... 
Environment, general | Cross-flow ultrafiltration | Aquatic colloids | Environment | Liquid chromatography-tandem mass spectrometry | Waste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution | Industrial Pollution Prevention | Atmospheric Protection/Air Quality Control/Air Pollution | Effluent | Pharmaceuticals | ENDOCRINE-DISRUPTING CHEMICALS | RIVER WATER | WASTE-WATER TREATMENT | PERSONAL CARE PRODUCTS | SEWAGE-TREATMENT PLANTS | TANDEM MASS-SPECTROMETRY | ENVIRONMENTAL SCIENCES | ACTIVATED-SLUDGE TREATMENT | REMOVAL | SOLID-PHASE EXTRACTION | Colloids - chemistry | Fresh Water - chemistry | Propranolol - analysis | Diclofenac - chemistry | Sulfamethoxazole - analysis | Carbamazepine - chemistry | Tamoxifen - chemistry | Thioridazine - chemistry | Indomethacin - analysis | Phenethylamines - analysis | Sewage - chemistry | Carbamazepine - analysis | Phenethylamines - chemistry | Water Pollutants, Chemical - chemistry | Propranolol - chemistry | Environmental Restoration and Remediation - methods | Water Pollutants, Chemical - analysis | Meclofenamic Acid - chemistry | Tamoxifen - analysis | Sulfamethoxazole - chemistry | Meclofenamic Acid - analysis | Diclofenac - analysis | Pharmaceutical Preparations - chemistry | Indomethacin - chemistry | Thioridazine - analysis | Pharmaceutical Preparations - analysis | Propranolol hydrochloride | Sewage | Purification | Analysis | Green technology | Water, Underground | Air pollution | Tamoxifen | Mass spectrometry | Sediments (Geology) | Carbamazepine | Water pollution | Bioavailability | Risk assessment | Water quality | Index Medicus
Journal Article
Analytical Chemistry, ISSN 0003-2700, 03/2005, Volume 77, Issue 5, pp. 1345 - 1353
High-throughput screening of combinatorial libraries has evolved from studying large diverse libraries to analyzing small, structurally similar, focused... 
EXCLUSION CHROMATOGRAPHY | CHEMISTRY, ANALYTICAL | ULTRAFILTRATION-MASS-SPECTROMETRY | AFFINITY CAPILLARY-ELECTROPHORESIS | LIGANDS | COMBINATORIAL LIBRARIES | GEL-FILTRATION | SMALL-MOLECULE LIBRARIES | BETA-LACTAM ANTIBIOTICS | PLASMA-PROTEIN BINDING | PULSED ULTRAFILTRATION | beta-Lactams - metabolism | Quinidine - chemistry | Chromatography, Gel - methods | Humans | Warfarin - metabolism | Tryptophan - chemistry | Warfarin - chemistry | Sarcosine - metabolism | Acecainide - analysis | Imipramine - chemistry | Indomethacin - metabolism | Tryptophan - metabolism | Dansyl Compounds - analysis | Dansyl Compounds - chemistry | beta-Lactams - analysis | Sarcosine - analogs & derivatives | Dansyl Compounds - metabolism | Serum Albumin - chemistry | Tandem Mass Spectrometry - methods | Indomethacin - analysis | Quinidine - metabolism | Reproducibility of Results | Sarcosine - analysis | Imipramine - analysis | Serum Albumin - analysis | beta-Lactams - chemistry | Pharmaceutical Preparations - metabolism | Acecainide - chemistry | Combinatorial Chemistry Techniques | Warfarin - analysis | Imipramine - metabolism | Acecainide - metabolism | Pharmaceutical Preparations - chemistry | Sarcosine - chemistry | Indomethacin - chemistry | Protein Binding | Quinidine - analysis | Chromatography, Liquid - methods | Pharmaceutical Preparations - analysis | Serum Albumin - metabolism | Tryptophan - analysis | Liquid chromatography | Chemistry, Analytic | Research | Mass spectrometry | Studies | Solutions | Medical screening | Analysis | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 09/2013, Volume 170, Issue 2, pp. 268 - 278
Journal Article