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Circulation Research, ISSN 0009-7330, 10/2012, Volume 111, Issue 9, pp. 1125 - 1136
Journal Article
Nature, ISSN 0028-0836, 02/2011, Volume 470, Issue 7332, pp. 105 - 110
Studies in embryonic development have guided successful efforts to direct the differentiation of human embryonic and induced pluripotent stem cells (PSCs) into... 
VIVO | NEUROGENIN-3 | MULTIDISCIPLINARY SCIENCES | BETA-CELLS | ENDODERM | DEFINED CONDITIONS | GENERATION | SPECIFICATION | FATE | EFFICIENT DIFFERENTIATION | ENDOCRINE-CELLS | Body Patterning - drug effects | Intestines - drug effects | Wnt Proteins - pharmacology | Embryonic Stem Cells - cytology | Humans | Endoderm - embryology | Intestines - embryology | Organogenesis - drug effects | Intestines - anatomy & histology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Time Factors | Endoderm - cytology | Fibroblast Growth Factor 4 - pharmacology | Cell Culture Techniques | Culture Media - chemistry | Induced Pluripotent Stem Cells - cytology | Basic Helix-Loop-Helix Transcription Factors - genetics | Induced Pluripotent Stem Cells - drug effects | Cells, Cultured | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Microvilli - drug effects | Activins - pharmacology | Embryonic Stem Cells - drug effects | Cell Differentiation - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Endoderm - drug effects | Culture Media - pharmacology | Morphogenesis - drug effects | Wnt3 Protein | Wnt3A Protein | Intestines - cytology | Physiological aspects | Intestines | Genetic aspects | Health aspects | Endoderm | Stem cells | Proteins | Studies | Index Medicus | posterior endoderm | intestine | FGF | transplantation | colon | drug transport | Wnt | progenitor cell
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 08/2015, Volume 17, Issue 8, pp. 994 - 1003
The use of human pluripotent stem cells for in vitro disease modelling and clinical applications requires protocols that convert these cells into relevant... 
DIRECTED DIFFERENTIATION | IN-VIVO | MOUSE | DEFINITIVE ENDODERM | GROWTH-FACTOR | HUMAN BLASTOCYSTS | STROMAL CELLS | WNT | CULTURE | LINES | CELL BIOLOGY | Coculture Techniques | Humans | Endothelial Cells - transplantation | Glycogen Synthase Kinase 3 beta | Cell Lineage - drug effects | Dose-Response Relationship, Drug | Human Umbilical Vein Endothelial Cells - physiology | Transfection | Time Factors | Gene Expression Regulation, Developmental | Transcription, Genetic | Myocytes, Smooth Muscle - drug effects | Proto-Oncogene Proteins c-sis - pharmacology | Myocytes, Smooth Muscle - transplantation | Vascular Endothelial Growth Factor A - pharmacology | Endothelial Cells - physiology | Muscle, Smooth, Vascular - physiology | Muscle, Smooth, Vascular - drug effects | Biomarkers - metabolism | Cell Line | Induced Pluripotent Stem Cells - enzymology | Induced Pluripotent Stem Cells - drug effects | Induced Pluripotent Stem Cells - physiology | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Myocytes, Smooth Muscle - enzymology | Induced Pluripotent Stem Cells - transplantation | Myocytes, Smooth Muscle - physiology | Gene Expression Profiling - methods | Muscle, Smooth, Vascular - transplantation | Glycogen Synthase Kinase 3 - metabolism | Mice, SCID | Muscle, Smooth, Vascular - cytology | Metabolomics - methods | Bone Morphogenetic Protein 4 - pharmacology | Phenotype | Animals | Wnt Signaling Pathway - drug effects | Cell Differentiation - drug effects | Mice, Inbred NOD | Protein Kinase Inhibitors - pharmacology | Endothelial Cells - enzymology | Muscle, Smooth, Vascular - enzymology | Neovascularization, Physiologic | Endothelial Cells - drug effects | Usage | Cell research | Growth | Stem cells | Muscle cells | Research | Cell differentiation | Endothelium | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 02/2009, Volume 104, Issue 4, pp. e30 - e41
Human induced pluripotent stem (iPS) cells hold great promise for cardiovascular research and therapeutic applications, but the ability of human iPS cells to... 
Action potential | Differentiation | Embryonic stem cells | Induced pluripotent stem cells | Cardiomyocyte | CARDIAC & CARDIOVASCULAR SYSTEMS | differentiation | embryonic stem cells | CARDIAC MYOCYTES | INDUCTION | action potential | LINES | OCT4 | cardiomyocyte | HUMAN FIBROBLASTS | PERIPHERAL VASCULAR DISEASE | induced pluripotent stem cells | GENERATION | HEMATOLOGY | DEVELOP | Embryonic Stem Cells - metabolism | RNA-Binding Proteins - genetics | Cell Proliferation | Homeodomain Proteins - metabolism | Humans | Myocardial Contraction - drug effects | SOXB1 Transcription Factors - metabolism | Action Potentials | Octamer Transcription Factor-3 - genetics | Cell Differentiation - genetics | SOXB1 Transcription Factors - genetics | Time Factors | Cell Line | Nanog Homeobox Protein | Transduction, Genetic | Sarcomeres - metabolism | Pluripotent Stem Cells - physiology | Gene Expression Regulation | Adrenergic beta-Agonists - pharmacology | Embryonic Stem Cells - physiology | Homeodomain Proteins - genetics | Pluripotent Stem Cells - metabolism | Phenotype | Myocytes, Cardiac - drug effects | Embryonic Stem Cells - drug effects | Myocytes, Cardiac - physiology | Isoproterenol - pharmacology | Octamer Transcription Factor-3 - metabolism | Pluripotent Stem Cells - drug effects | Myocytes, Cardiac - metabolism | RNA-Binding Proteins - metabolism | Index Medicus
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2014, Volume 72, pp. 296 - 304
Abstract Background Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) have great potential as a cell source for therapeutic... 
Cardiovascular | Cardiomyocyte maturation | Mitochondria | Tri-iodo-l-thyronine | Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) | Contractile force | CARDIAC & CARDIOVASCULAR SYSTEMS | FUNCTIONAL MATURATION | THYROID-HORMONE | SIZE | LINES | CELL BIOLOGY | PASSIVE STIFFNESS | CARDIAC-HYPERTROPHY | FETAL | DIFFERENTIATION | SECRETION | Tri-iodo-L-thyronine | UP-REGULATION | Calcium - metabolism | Humans | Culture Media, Conditioned - pharmacology | Lung - cytology | Oxidative Phosphorylation - drug effects | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Lung - metabolism | Induced Pluripotent Stem Cells - cytology | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Triiodothyronine - pharmacology | Gene Expression | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Induced Pluripotent Stem Cells - drug effects | Myocytes, Cardiac - cytology | Sarcomeres - drug effects | Sarcomeres - metabolism | Cells, Cultured | Mitochondria - metabolism | Mitochondria - drug effects | Animals | Myocytes, Cardiac - drug effects | Cell Differentiation - drug effects | Fibroblasts - drug effects | Lung - drug effects | Myocytes, Cardiac - metabolism | Fibroblasts - cytology | Mice | Cell Cycle - drug effects | Sarcoplasmic Reticulum Calcium-Transporting ATPases - genetics | Analysis | Stem cells | Heart cells | Index Medicus | Human induced pluripotent stem cells-derived cardiomyocytes (hiPSC-CMs)
Journal Article