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BioImpacts, ISSN 2228-5660, 12/2018, Volume 8, Issue Suppl 1, pp. S1 - S129
Journal Article
Nature, ISSN 0028-0836, 02/2012, Volume 482, Issue 7384, pp. 216 - U107
Our understanding of Alzheimer's disease pathogenesis is currently limited by difficulties in obtaining live neurons from patients and the inability to model... 
AMYLOID BETA-PROTEIN | APP | MICROTUBULE-BINDING | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | DOWN-SYNDROME | MOUSE MODEL | TAU | DYSFUNCTION | FIBROBLASTS | SENILE PLAQUES | Neurons - pathology | Coculture Techniques | Humans | Middle Aged | Amyloid beta-Peptides - secretion | tau Proteins - metabolism | Male | Phosphoproteins - metabolism | Endosomes - metabolism | Synapsins - metabolism | Alzheimer Disease - pathology | Cellular Reprogramming | Protease Inhibitors - pharmacology | Amyloid beta-Protein Precursor - secretion | Proteolysis | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Aged, 80 and over | Female | Neurons - metabolism | Phosphorylation - drug effects | Neurons - drug effects | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Astrocytes - cytology | Biomarkers - metabolism | Induced Pluripotent Stem Cells - pathology | Peptide Fragments - metabolism | Cells, Cultured | Peptide Fragments - secretion | Glycogen Synthase Kinase 3 - metabolism | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Models, Biological | Alzheimer Disease - metabolism | Fibroblasts - cytology | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Enzyme Activation | Messenger RNA | Synthesis | Glycogen | Stem cells | Physiological aspects | Research | Alzheimer's disease | Proteins | Phosphorylation | Neurons | Efficiency | Genomes | Mutation | Alzheimers disease
Journal Article
Journal Article
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2014, Volume 72, pp. 296 - 304
Abstract Background Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) have great potential as a cell source for therapeutic... 
Cardiovascular | Cardiomyocyte maturation | Mitochondria | Tri-iodo-l-thyronine | Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) | Contractile force | CARDIAC & CARDIOVASCULAR SYSTEMS | FUNCTIONAL MATURATION | THYROID-HORMONE | SIZE | LINES | CELL BIOLOGY | PASSIVE STIFFNESS | CARDIAC-HYPERTROPHY | FETAL | DIFFERENTIATION | SECRETION | Tri-iodo-L-thyronine | UP-REGULATION | Calcium - metabolism | Humans | Culture Media, Conditioned - pharmacology | Lung - cytology | Oxidative Phosphorylation - drug effects | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Lung - metabolism | Induced Pluripotent Stem Cells - cytology | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Triiodothyronine - pharmacology | Gene Expression | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Induced Pluripotent Stem Cells - drug effects | Myocytes, Cardiac - cytology | Sarcomeres - drug effects | Sarcomeres - metabolism | Cells, Cultured | Mitochondria - metabolism | Mitochondria - drug effects | Animals | Myocytes, Cardiac - drug effects | Cell Differentiation - drug effects | Fibroblasts - drug effects | Lung - drug effects | Myocytes, Cardiac - metabolism | Fibroblasts - cytology | Mice | Cell Cycle - drug effects | Sarcoplasmic Reticulum Calcium-Transporting ATPases - genetics | Analysis | Stem cells | Heart cells | Index Medicus | Human induced pluripotent stem cells-derived cardiomyocytes (hiPSC-CMs)
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 30, pp. 13426 - 13431
Diabetes mellitus is characterized by either the inability to produce insulin (type 1 diabetes) or as insensitivity to insulin secreted by the body (type 2... 
Beta cells | Hyperglycemia | Diabetes complications | Somatic cells | Induced pluripotent stem cells | Transplantation | Type 2 diabetes mellitus | Insulin | Cellular differentiation | Type 1 diabetes mellitus | Diabetes | Somatic cell programming | Cellular therapy | Stem cells | stem cells | SOMATIC-CELLS | DEFINED FACTORS | ISLETS | MULTIDISCIPLINARY SCIENCES | INDUCTION | cellular therapy | TRANSPLANTATION | THERAPY | MOLECULAR PHYSIOLOGY | somatic cell programming | INSULIN-PRODUCING CELLS | GENERATION | DIFFERENTIATION | diabetes | Glycated Hemoglobin A - analysis | Insulin - analysis | Diabetes Mellitus, Type 1 - surgery | Humans | Hyperglycemia - complications | Green Fluorescent Proteins - genetics | Diabetes Mellitus, Type 1 - complications | Insulin-Secreting Cells - metabolism | Mice, Inbred DBA | Cell Differentiation | Insulin-Secreting Cells - cytology | Induced Pluripotent Stem Cells - cytology | Insulin Secretion | Diabetes Mellitus, Type 2 - complications | Diabetes Mellitus, Type 2 - surgery | Disease Models, Animal | Induced Pluripotent Stem Cells - metabolism | Green Fluorescent Proteins - metabolism | Hyperglycemia - prevention & control | Blood Glucose - analysis | Induced Pluripotent Stem Cells - transplantation | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Insulin - metabolism | Animals | Hyperglycemia - blood | Mice, Nude | Fluorescent Antibody Technique | Mice | Insulin-Secreting Cells - transplantation | Cell Transplantation - methods | Biological Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e52787
Murine and human iPSC-NS/PCs (induced pluripotent stem cell-derived neural stem/progenitor cells) promote functional recovery following transplantation into... 
FIBERS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | EXPRESSION PROFILE | GENE-EXPRESSION | FETAL-BRAIN | STEM/PROGENITOR CELLS | PLURIPOTENCY | GENERATION | GROWTH-FACTOR | TRANSPLANTATION | Humans | Induced Pluripotent Stem Cells - secretion | Motor Neurons - pathology | Recovery of Function | Spinal Cord Injuries - pathology | Microglia - physiology | Spinal Cord - pathology | Neural Stem Cells - transplantation | Female | Cell Differentiation | Calcitonin Gene-Related Peptide - metabolism | Spinal Cord Injuries - therapy | Hand Strength | Induced Pluripotent Stem Cells - physiology | Nerve Growth Factors - secretion | Callithrix | Cell Survival | Induced Pluripotent Stem Cells - transplantation | Cells, Cultured | Neural Stem Cells - physiology | Nerve Regeneration | Spinal Cord - blood supply | Demyelinating Diseases - prevention & control | Motor Neurons - metabolism | Locomotion | Animals | Neural Stem Cells - secretion | Cicatrix - pathology | Spinal Cord - physiopathology | Cell Transformation, Neoplastic - pathology | Neovascularization, Physiologic | Stem Cell Transplantation - adverse effects | Transplantation | Spinal cord injuries | RNA | Stem cells | Cell culture | Spinal cord | Recovery of function | Stem cell transplantation | Spinal cord injury | Bone surgery | Recovery | Proteins | Angiogenesis | Allografts | Demyelination | Rodents | Fibroblasts | Primates | Physiology | Injuries | Injury analysis | Cloning | Regrowth | Attorneys | Tumorigenicity | Neurotrophic factors | Gene expression | Polymerase chain reaction | Medicine | Orthopedics | Cells (biology) | Neural stem cells | Skin | Laboratory animals | Human behavior | Pluripotency
Journal Article
Circulation Research, ISSN 0009-7330, 07/2017, Volume 121, Issue 6, pp. E22 - E22
RATIONALE:Cardiac myocytes derived from pluripotent stem cells have demonstrated the potential to mitigate damage of the infarcted myocardium and improve left... 
MIGRATION | magnetic resonance imaging | CARDIAC & CARDIOVASCULAR SYSTEMS | pluripotent stem cells | myocardial infarction | HEART-FAILURE | INFARCTED MYOCARDIUM | FACTOR-I | CARDIOMYOCYTES | MODEL | manganese | G-CSF | RAT HEARTS | REPAIR | THERAPY | cell therapy | PERIPHERAL VASCULAR DISEASE | cytokines | HEMATOLOGY | Cell Line | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Cytokines - metabolism | Myocytes, Cardiac - cytology | Paracrine Communication | Humans | Induced Pluripotent Stem Cells - transplantation | Cells, Cultured | Myocardial Infarction - therapy | Myocytes, Cardiac - transplantation | Stem Cell Transplantation - methods | Animals | Embryonic Stem Cells - transplantation | Myocytes, Cardiac - metabolism | Mice | Induced Pluripotent Stem Cells - cytology | Cytokines - genetics | Induced Pluripotent Stem Cells - metabolism | Myocardial infarction | Cell therapy | Cytokines | Magnetic resonance imaging | Pluripotent stem cells | Manganese | Immunohistochemistry | Phenotypes | Bioluminescence | Nuclear magnetic resonance--NMR | Heart transplantation | Embryo cells | Coronary artery | Stem cell transplantation | Paracrine signalling | Cardiomyocytes | Myocytes | Secretions | Gene expression | Embryos | Allografts | Stem cells | Myocardium | Ventricle | Heart diseases | Pluripotency | Inhibitory postsynaptic potentials | magnetic resonance imaging (MRI) | Stem Cells | cell transplantation | Myocardial Biology | manganese-enhanced MRI (MEMRI)
Journal Article