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1. Full Text Induction of pluripotent stem cells transplantation therapy for ischemic stroke
by Jiang, Mei and Lv, Lei and Ji, Haifeng and Yang, Xuelian and Zhu, Wei and Cai, Liying and Gu, Xiaju and Chai, Changfeng and Huang, Shu and Sun, Jian and Dong, Qiang
Molecular and Cellular Biochemistry, ISSN 0300-8177, 8/2011, Volume 354, Issue 1, pp. 67 - 75
Stroke can cause permanent neurological damage, complications, and even death. However, there is no treatment exists to restore its lost function. Human... 
Life Sciences | Biochemistry, general | Transplantation therapy | Transcription factors | Induced pluripotent stem cells | Brain ischemia | Fibroblasts | Oncology | Medical Biochemistry | Cardiology | SURVIVAL | FUNCTIONAL RECOVERY | RATS | MODEL | NEUROLOGICAL DEFICITS | CELL BIOLOGY | LIVER | NEURONS | GENERATION | BRAIN | Coculture Techniques | Humans | Middle Aged | Alkaline Phosphatase - metabolism | Cerebral Cortex - pathology | Male | Transplantation, Heterologous | Recovery of Function | Antigens, Differentiation - metabolism | Female | Cell Differentiation | Induced Pluripotent Stem Cells - cytology | Stroke - therapy | Disease Models, Animal | Induced Pluripotent Stem Cells - metabolism | Recombinant Proteins - metabolism | Brain Ischemia - therapy | Induced Pluripotent Stem Cells - transplantation | Cells, Cultured | Rats | Recombinant Proteins - genetics | Transcription Factors - genetics | Rats, Sprague-Dawley | Gait Disorders, Neurologic - therapy | Transcription Factors - metabolism | Animals | Fibroblasts - cytology | Stem cell research | Brain | Ischemia | Stem cells | Transplantation | Embryonic stem cells | Health aspects | Neurology | Stroke | Transplants & implants | Animal models | sensorimotor system | Oct-4 protein | stem cell transplantation | Embryo cells | Recovery of function | Grafting | Ethics | Cerebral blood flow | Buffers | Inhibitory postsynaptic potentials | Index Medicus
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2. Full Text Immunogenicity of induced pluripotent stem cells
by Zhao, Tongbiao and Zhang, Zhen-Ning and Rong, Zhili and Xu, Yang
Nature, ISSN 0028-0836, 06/2011, Volume 474, Issue 7350, pp. 212 - 216
Induced pluripotent stem cells (iPSCs), reprogrammed from somatic cells with defined factors, hold great promise for regenerative medicine as the renewable... 
DEFINED FACTORS | INTEGRATION | MULTIDISCIPLINARY SCIENCES | GENERATION | HUMAN SOMATIC-CELLS | EXPRESSION | FIBROBLASTS | Induced Pluripotent Stem Cells - transplantation | Mice, Inbred C57BL | Cells, Cultured | Teratoma - immunology | Male | Up-Regulation - genetics | Transplantation, Homologous - immunology | Cellular Reprogramming - immunology | Animals | Up-Regulation - immunology | Plasmids - genetics | Teratoma - genetics | Transplantation, Isogeneic - immunology | Fibroblasts - cytology | Induced Pluripotent Stem Cells - immunology | Mice | Graft Rejection - immunology | Graft Rejection - genetics | Induced Pluripotent Stem Cells - cytology | Cellular Reprogramming - genetics | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Immunogenetics | Immune response | Regenerative medicine | Research | Embryonic stem cells | T cells | Properties | Health aspects | Proteins | Epigenetics | Cloning | Stem cells | Index Medicus
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3. Full Text Notch-1 mediated cardiac protection following embryonic and induced pluripotent stem cell transplantation in doxorubicin-induced heart failure
by Merino, Hilda and Singla, Dinender K
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, pp. e101024 - e101024
Doxorubicin (DOX), an effective chemotherapeutic drug used in the treatment of various cancers, is limited in its clinical applications due to cardiotoxicity.... 
INDUCED CARDIOTOXICITY | OXIDATIVE STRESS | MYOCARDIAL-INFARCTION | REGENERATION | MULTIDISCIPLINARY SCIENCES | INHIBIT APOPTOSIS | MECHANISMS | PROLIFERATION | INDUCED CARDIOMYOPATHY | MYOCYTE DIFFERENTIATION | CARDIOMYOCYTES | Antibiotics, Antineoplastic - pharmacology | Heart Failure - physiopathology | Antibiotics, Antineoplastic - adverse effects | Heart Failure - metabolism | Receptor, Notch1 - biosynthesis | Stem Cell Transplantation | Allografts | Animals | Embryonic Stem Cells - transplantation | Pluripotent Stem Cells - transplantation | Cell Line, Tumor | Mice | Doxorubicin - adverse effects | Doxorubicin - pharmacology | Heart Failure - chemically induced | Heart | Heart failure | Anthracyclines | Transplantation | Heart attack | Stem cells | Myocardial infarction | Cell culture | Oxidative stress | Media (culture) | Heart attacks | Transplants & implants | Cardiomyopathy | Leukemia | Stem cell transplantation | AKT protein | Heart function | Doxorubicin | Bone marrow | Heart diseases | Drug dosages | Echocardiography | Therapeutic applications | Heart transplantation | Coronary artery | Data processing | Gelatinase B | Ostomy | Coronary vessels | Fibrosis | Infarction | Notch protein | Ventricle | Pluripotency | PTEN protein | Apoptosis | Veins & arteries | Index Medicus
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4. Full Text Fate of induced pluripotent stem cells following transplantation to murine seminiferous tubules
by Durruthy, Jens Durruthy and Ramathal, Cyril and Sukhwani, Meena and Fang, Fang and Cui, Jun and Orwig, Kyle E and Reijo Pera, Renee A
Human Molecular Genetics, ISSN 0964-6906, 2014, Volume 23, Issue 12, pp. 3071 - 3084
Studies of human germ cell development are limited in large part by inaccessibility of germ cells during development. Moreover, although several studies have... 
DAZL | VASA | IN-VITRO | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | 5-HYDROXYMETHYLCYTOSINE | DIFFERENTIATION | FETAL | PRIMORDIAL GERM-CELLS | IPS CELLS | Cell Line | Epigenesis, Genetic | Humans | Induced Pluripotent Stem Cells - transplantation | Gene Expression Regulation | Male | Gene Expression Profiling | Cellular Reprogramming | Transplantation, Heterologous - methods | Animals | Mice, Nude | Seminiferous Tubules - metabolism | Spermatozoa - physiology | Cell Differentiation | Mice | Spermatozoa - cytology | Induced Pluripotent Stem Cells - metabolism | Index Medicus
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5. Full Text Derivation of novel human ground state naive pluripotent stem cells
by Gafni, Ohad and Weinberger, Leehee and Mansour, Abed Alfatah and Manor, Yair S and Chomsky, Elad and Ben-Yosef, Dalit and Kalma, Yael and Viukov, Sergey and Maza, Itay and Zviran, Asaf and Rais, Yoach and Shipony, Zohar and Mukamel, Zohar and Krupalnik, Vladislav and Zerbib, Mirie and Geula, Shay and Caspi, Inbal and Schneir, Dan and Shwartz, Tamar and Gilad, Shlomit and Amann-Zalcenstein, Daniela and Benjamin, Sima and Amit, Ido and Tanay, Amos and Massarwa, Rada and Novershtern, Noa and Hanna, Jacob H
Nature, ISSN 0028-0836, 2013, Volume 504, Issue 7479, pp. 282 - 286
Mouse embryonic stem (ES) cells are isolated from the inner cell mass of blastocysts, and can be preserved in vitro in a naive inner-cell-mass-like... 
INACTIVATION | BLASTOCYSTS | MULTIDISCIPLINARY SCIENCES | LINES | Chromatin - metabolism | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Epigenesis, Genetic | Humans | Male | Regenerative Medicine | Promoter Regions, Genetic - genetics | Cellular Reprogramming | DNA Methylation | Chimera - embryology | Female | Germ Layers - cytology | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - metabolism | Reproducibility of Results | Signal Transduction | Induced Pluripotent Stem Cells - transplantation | Blastocyst - cytology | Morula - cytology | Organogenesis | Animals | Embryo, Mammalian - embryology | Embryo, Mammalian - cytology | Mice | Histones - metabolism | X Chromosome Inactivation | Epigenetic inheritance | Stem cells | Blastocyst | Physiological aspects | Genetic aspects | Research | Genetic transcription | Molecular biology | Methylation | Cell culture | Cytokines | DNA methylation | Epigenetics | Kinases | Embryos | Index Medicus
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6. Full Text Induced Pluripotent Stem Cells: Past, Present, and Future
by Yamanaka, Shinya
Cell Stem Cell, ISSN 1934-5909, 06/2012, Volume 10, Issue 6, pp. 678 - 684
The development of iPSCs reflected the merging of three major scientific streams and has in turn led to additional new branches of investigation. However,... 
SOMATIC-CELLS | HUMAN ES | MOUSE | GENE-EXPRESSION | DIRECT CONVERSION | FAMILIAL ALZHEIMERS-DISEASE | HUMAN FIBROBLASTS | GENERATION | DIFFERENTIATION | IPS CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Cell Differentiation | Animals | Induced Pluripotent Stem Cells - physiology | Induced Pluripotent Stem Cells - cytology | Humans | Induced Pluripotent Stem Cells - transplantation | Index Medicus
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7. Full Text Treatment of a Mouse Model of Spinal Cord Injury by Transplantation of Human Induced Pluripotent Stem Cell‐Derived Long‐Term Self‐Renewing Neuroepithelial‐Like Stem Cells
by Fujimoto, Yusuke and Abematsu, Masahiko and Falk, Anna and Tsujimura, Keita and Sanosaka, Tsukasa and Juliandi, Berry and Semi, Katsunori and Namihira, Masakazu and Komiya, Setsuro and Smith, Austin and Nakashima, Kinichi
STEM CELLS, ISSN 1066-5099, 06/2012, Volume 30, Issue 6, pp. 1163 - 1173
Because of their ability to self‐renew, to differentiate into multiple lineages, and to migrate toward a damaged site, neural stem cells (NSCs), which can be... 
Neural stem cells | Transplantation | Spinal cord injury | Induced pluripotent stem cells | Regenerative medicine | FUNCTIONAL RECOVERY | ADULT RATS | REGENERATION | PROMOTE LOCOMOTOR RECOVERY | FIBROBLASTS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | NS CELLS | MICE | FETAL | DIFFERENTIATION | HEMATOLOGY | PRECURSOR CELLS | Immunohistochemistry | Humans | Induced Pluripotent Stem Cells - transplantation | Cells, Cultured | Spinal Cord Injuries - surgery | Mice, SCID | Spinal Cord Injuries - pathology | Stem Cell Transplantation - methods | Animals | Neural Stem Cells - transplantation | Female | Mice, Inbred NOD | Mice | Induced Pluripotent Stem Cells - cytology | Cell Differentiation - physiology | Neural Stem Cells - metabolism | Disease Models, Animal | Spinal cord injuries | Stem cells | Index Medicus
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8. Full Text Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice
by Lian, Qizhou and Zhang, Yuelin and Zhang, Jinqiu and Zhang, Hua Kun and Wu, Xingang and Zhang, Yang and Lam, Francis Fu-Yuen and Kang, Sarang and Xia, Jian Chuan and Lai, Wing-Hong and Au, Ka-Wing and Chow, Yen Yen and Siu, Chung-Wah and Lee, Chuen-Neng and Tse, Hung-Fat
Circulation, ISSN 0009-7322, 03/2010, Volume 121, Issue 9, pp. 1113 - 1123
Background-Aging and aging-related disorders impair the survival and differentiation potential of bone marrow mesenchymal stem cells (MSCs) and limit their... 
Peripheral vascular disease | Transplantation | Ischemia | Repair | Induced pluripotent stem cells | Mesenchymal stem cells | repair | CAPACITY | CARDIAC & CARDIOVASCULAR SYSTEMS | mesenchymal stem cells | transplantation | MONONUCLEAR-CELLS | induced pluripotent stem cells | DIFFERENTIATION | peripheral vascular disease | ischemia | Chondrocytes - cytology | Humans | Recombinant Fusion Proteins - physiology | Adipocytes - cytology | Transplantation, Heterologous | Recovery of Function | Intercellular Signaling Peptides and Proteins - physiology | Cell Differentiation | Myocytes, Smooth Muscle - cytology | Mesenchymal Stromal Cells - physiology | Cell Line | Clone Cells - transplantation | Pluripotent Stem Cells - cytology | Transduction, Genetic | Paracrine Communication | Osteocytes - cytology | Intercellular Signaling Peptides and Proteins - genetics | Mice, SCID | Genetic Vectors - genetics | Teratoma - pathology | Animals | Endothelial Cells - cytology | Hindlimb - blood supply | Pluripotent Stem Cells - transplantation | Ischemia - surgery | Fibroblasts - cytology | Mice | Care and treatment | Patient outcomes | Stem cells | Physiological aspects | Models | Bone marrow cells | Research | Index Medicus | Abridged Index Medicus
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9. Full Text Transplantation and tracking of human-induced pluripotent stem cells in a pig model of myocardial infarction: Assessment of cell survival, engraftment, and distribution by hybrid single photon emission computed tomography/computed tomography of sodium iodide symporter transgene expression
by Templin, Christian and Zweigerdt, Robert and Schwanke, Kristin and Olmer, Ruth and Ghadri, Jelena-Rima and Emmert, Maximilian Y and Müller, Ennio and Küest, Silke M and Cohrs, Susan and Schibli, Roger and Kronen, Peter and Hilbe, Monika and Reinisch, Andreas and Strunk, Dirk and Haverich, Axel and Hoerstrup, Simon and Lüscher, Thomas F and Kaufmann, Philipp A and Landmesser, Ulf and Martin, Ulrich
Circulation, ISSN 0009-7322, 07/2012, Volume 126, Issue 4, pp. 430 - 439
Background-Evaluation of novel cellular therapies in large-animal models and patients is currently hampered by the lack of imaging approaches that allow for... 
induced pluripotent stem cells | myocardial infarction in pig | sodium iodide symporter (NIS) | imaging | iPS cell | CARDIOMYOPLASTY | CARDIAC & CARDIOVASCULAR SYSTEMS | HIGHLY ENRICHED CARDIOMYOCYTES | SUSPENSION-CULTURE | RAT HEARTS | REPAIR | IN-VIVO | EXPANSION | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | GENERATION | THERAPIES | HEMATOLOGY | Humans | Tomography, X-Ray Computed | Positron-Emission Tomography | Feasibility Studies | Multimodal Imaging | Myocardial Infarction - therapy | Swine | Myocardial Infarction - pathology | Myocardium - metabolism | Cell Differentiation | Transgenes | Disease Models, Animal | Gene Expression | Cell Survival | Graft Survival | Myocardium - pathology | Treatment Outcome | Myocardial Infarction - metabolism | Symporters - metabolism | Heart - diagnostic imaging | Pluripotent Stem Cells - metabolism | Injections | Stem Cell Transplantation - methods | Animals | Pluripotent Stem Cells - transplantation | Symporters - genetics | In Vitro Techniques | Usage | Care and treatment | Analysis | Stem cells | Physiological aspects | SPECT imaging | Genetic aspects | Transplantation | Diagnosis | Gene expression | Health aspects | Heart attack | Index Medicus | Abridged Index Medicus
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10. Full Text Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
by Junying Yu and Kejin Hu and Kim Smuga-Otto and Shulan Tian and Ron Stewart and Igor I. Slukvin and James A. Thomson
Science, ISSN 0036-8075, 5/2009, Volume 324, Issue 5928, pp. 797 - 801
Reprogramming differentiated human cells to induced pluripotent stem (iPS) cells has applications in basic biology, drug development, and transplantation.... 
Genetic vectors | Somatic cells | Induced pluripotent stem cells | Cell lines | Stem cells | Fibroblasts | Reports | Foreskin | Transgenes | Embryonic stem cells | Liver cells | PLASMIDS | MULTIDISCIPLINARY SCIENCES | STABLE REPLICATION | GENERATION | INDUCTION | REPLICON | EPSTEIN-BARR-VIRUS | FIBROBLASTS | Embryonic Stem Cells - cytology | Pluripotent Stem Cells - cytology | Epstein-Barr Virus Nuclear Antigens - genetics | Humans | Gene Expression Profiling | Transcription Factors - genetics | Cellular Reprogramming | Pluripotent Stem Cells - metabolism | Transfection | Plasmids | Cell Shape | Pluripotent Stem Cells - transplantation | Cell Differentiation | Clone Cells | Genetic Vectors | Technology application | Genetic aspects | Transplantation | Pharmaceutical industry | Genetic engineering | Cellular biology | Genomics | Index Medicus
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