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Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 596 - 605
T follicular helper (Tfh) cells provide help to B cells and are crucial for establishment of germinal center (GC) reactions, including production of... 
CXC CHEMOKINE RECEPTOR-5 | DENDRITIC CELLS | BCL6 | ANTIBODY-PRODUCTION | IN-VIVO DEPLETION | IMMUNE-RESPONSES | DYNAMICS | GENERATION | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | Ovalbumin - immunology | Germinal Center - immunology | Humans | CD40 Ligand - immunology | CD3 Complex - genetics | CD40 Antigens - metabolism | CD40 Ligand - metabolism | Flow Cytometry | Inducible T-Cell Co-Stimulator Ligand - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Antibodies - immunology | B-Lymphocytes - metabolism | Inducible T-Cell Co-Stimulator Protein - immunology | Inducible T-Cell Co-Stimulator Ligand - immunology | Receptors, CXCR5 - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | Receptors, CXCR5 - genetics | Immunization - methods | Mice, Inbred C57BL | Immunophenotyping | Mice, Transgenic | Protein Binding - immunology | CD3 Complex - metabolism | Receptors, CXCR5 - immunology | Mice, Knockout | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Ovalbumin - administration & dosage | CD3 Complex - immunology | Cell Line, Tumor | Lymphocyte Count | Antigens - immunology | Luminescent Proteins - genetics | Mice | Inducible T-Cell Co-Stimulator Protein - metabolism | CD40 Antigens - immunology | Luminescent Proteins - metabolism | Antigen-antibody reactions | Antigens | Genetic aspects | Genotype & phenotype | Rodents | Software | Experiments | Chemokines | Immune system
Journal Article
Blood, ISSN 0006-4971, 06/2014, Volume 123, Issue 25, pp. 3988 - 3998
Chronic graft-versus-host disease (cGVHD) is a leading cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Having shown... 
CRITERIA | CORD BLOOD TRANSPLANTATION | CHRONIC GVHD | CLINICAL-TRIALS | DIFFERENTIATION | ANTIBODY-RESPONSES | ICOS | HEMATOLOGY | VERSUS-HOST-DISEASE | IL-21 | CONSENSUS DEVELOPMENT PROJECT | Germinal Center - immunology | Receptors, Interleukin-21 - genetics | Germinal Center - drug effects | Graft vs Host Disease - metabolism | Bronchiolitis Obliterans - metabolism | Graft vs Host Disease - immunology | CD40 Ligand - immunology | Interleukins - metabolism | CD4-Positive T-Lymphocytes - immunology | T-Lymphocytes, Helper-Inducer - drug effects | Graft vs Host Disease - genetics | Interleukins - genetics | Bronchiolitis Obliterans - genetics | CD40 Antigens - metabolism | CD40 Ligand - metabolism | Flow Cytometry | Inducible T-Cell Co-Stimulator Ligand - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Interleukins - immunology | Inducible T-Cell Co-Stimulator Protein - genetics | Antibodies, Monoclonal - immunology | B-Lymphocytes - metabolism | Inducible T-Cell Co-Stimulator Protein - immunology | Antigens, CD20 - immunology | Inducible T-Cell Co-Stimulator Ligand - immunology | Receptors, CXCR5 - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | Receptors, CXCR5 - genetics | Receptors, Interleukin-21 - immunology | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Bronchiolitis Obliterans - immunology | Receptors, Interleukin-21 - metabolism | Antigens, CD20 - metabolism | Receptors, CXCR5 - immunology | Syndrome | Mice, Knockout | B-Lymphocytes - drug effects | Microscopy, Confocal | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Mice | Inducible T-Cell Co-Stimulator Protein - metabolism | Chronic Disease | CD40 Antigens - immunology | Transplantation
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2015, Volume 212, Issue 2, pp. 217 - 233
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2011, Volume 129, Issue 1, pp. 207 - 215.e5
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 10/2017, Volume 199, Issue 7, pp. 2305 - 2315
The proper regulation of ICOS and ICOS ligand (ICOSL) has been shown to be essential for maintaining proper immune homeostasis. Loss of either protein results... 
CONSTITUTIVE EXPRESSION | METALLOPROTEASE 10 | DISINTEGRIN | INDUCIBLE COSTIMULATOR | RECEPTOR | ADAM10 | ALPHA | DIFFERENTIATION | INDUCTION | IMMUNOLOGY | CLEAVAGE | Amyloid Precursor Protein Secretases - genetics | ADAM10 Protein - deficiency | ADAM10 Protein - genetics | Humans | ADAM10 Protein - metabolism | Encephalomyelitis, Autoimmune, Experimental - immunology | Homeostasis | Th1 Cells - immunology | T-Lymphocytes, Regulatory - immunology | Membrane Proteins - deficiency | Inducible T-Cell Co-Stimulator Ligand - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Membrane Proteins - metabolism | Disease Models, Animal | Inducible T-Cell Co-Stimulator Ligand - immunology | Membrane Proteins - genetics | Gene Expression Regulation | Amyloid Precursor Protein Secretases - metabolism | Animals | B-Lymphocytes - immunology | Inducible T-Cell Co-Stimulator Ligand - genetics | Amyloid Precursor Protein Secretases - deficiency | Th17 Cells - immunology | Mice | Pyroglyphidae - immunology | Shedding | Regulations | Immune response | Encephalomyelitis | Helper cells | House dust | Lymphocytes T | Immunity | Cell surface | Experimental allergic encephalomyelitis | Lymphocytes B | Lymphocytes | Internalization | Rodents | ICOS protein | Cell lines | Ligands | Immunity (humoral) | Aberration | Autoimmune diseases
Journal Article
Allergy, ISSN 0105-4538, 08/2017, Volume 72, Issue 8, pp. 1148 - 1155
Group 2 innate lymphoid cells (ILC2s) are a recently identified group of cells with the potent capability to produce Th2‐type cytokines such as interleukin... 
asthma | innate lymphoid cells | regulatory aspects | ICOS | Treg | FOXP3 EXPRESSION | ACTIVATION | TGF-BETA | LEUKOTRIENES | INDUCTION | IMMUNOLOGY | ALLERGY | IMMUNE-RESPONSES | INFLAMMATION | ASSOCIATION | IFN-ALPHA | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | Asthma - metabolism | Cytokines - metabolism | Cell Separation | Immunomodulation | Humans | Translational Medical Research | Respiratory Hypersensitivity - metabolism | Immunophenotyping | Th2 Cells - immunology | Immunity, Innate | Respiratory Hypersensitivity - immunology | Th2 Cells - metabolism | T-Lymphocytes, Regulatory - immunology | Animals | Inducible T-Cell Co-Stimulator Ligand - metabolism | T-Lymphocyte Subsets - metabolism | Asthma - immunology | Inflammation Mediators - metabolism | Biomarkers | Protein Binding | Inducible T-Cell Co-Stimulator Protein - metabolism | Disease Models, Animal | Interleukins | Analysis | Development and progression | B cells | T cells | Transforming growth factors | Asthma | Animal models | Lymphoid cells | Cytokines | Immunoregulation | Secretion | Interleukin | Medical services | Activation | Allergic diseases | Lymphocytes T | Inflammation | Interleukin 13 | T cell receptors | Eosinophilia | Respiratory tract | Cell activation | Interleukin 5 | Lymphocytes B | Lungs | Lymphocytes | ICOS protein | Interleukin 10 | Inhibition
Journal Article