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1. Full Text Antioxidants for male subfertility
by Showell, Marian G and Showell, Marian G and Mackenzie-Proctor, Rebecca and Mackenzie-Proctor, Rebecca and Brown, Julie and Brown, Julie and Yazdani, Anusch and Yazdani, Anusch and Stankiewicz, Marcin T and Stankiewicz, Marcin T and Hart, Roger J and Hart, Roger J
The Cochrane database of systematic reviews, ISSN 1469-493X, 2014, Volume 12, Issue 12, p. CD007411
Background Between 30% to 80% of male subfertility cases are considered to be due to the damaging effects of oxidative stress on sperm and 1 man in 20 will be... 
Sperm Count | Oxidative Stress [drug effects] | L-ACETYL-CARNITINE | BLIND RANDOMIZED-TRIAL | Humans | Spermatozoa [drug effects] | Male | CHROMATIN-STRUCTURE ASSAY | SEMEN PARAMETERS | Antioxidants [therapeutic use] | MEDICINE, GENERAL & INTERNAL | DNA Fragmentation | Abortion, Spontaneous [epidemiology] | Female | Pregnancy Rate | OXIDATIVE STRESS | Live Birth | SEMINAL PLASMA | ZINC-SULFATE | SPERM DNA FRAGMENTATION | Randomized Controlled Trials as Topic | Sperm Motility [drug effects] | Pregnancy | IDIOPATHIC MALE-INFERTILITY | DNA Damage | Infertility, Male [drug therapy; etiology] | COMBINED L-CARNITINE | Infertility, Male - drug therapy | Infertility, Male - etiology | Spermatozoa - drug effects | Sperm Motility - drug effects | Abortion, Spontaneous - epidemiology | Antioxidants - therapeutic use | Oxidative Stress - drug effects
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2. Full Text The role of sperm oxidative stress in male infertility and the significance of oral antioxidant therapy
by Gharagozloo, Parviz and Aitken, R. John
Human Reproduction, ISSN 0268-1161, 7/2011, Volume 26, Issue 7, pp. 1628 - 1640
Oxidative stress in the male germ line is thought to affect male fertility and impact upon normal embryonic development. Accordingly, fertility specialists are... 
human spermatozoa | antioxidant therapy | oxidative stress | reactive oxygen species | L-ACETYL-CARNITINE | BLIND RANDOMIZED-TRIAL | SEMINAL PLASMA | CHROMATIN-STRUCTURE ASSAY | OBSTETRICS & GYNECOLOGY | REPRODUCTIVE BIOLOGY | DNA INTEGRITY TESTS | HUMAN-SPERMATOZOA | HYDROGEN-PEROXIDE | IN-VITRO FERTILIZATION | PLACEBO-CONTROLLED TRIAL | COMBINED L-CARNITINE | Infertility, Male - drug therapy | Oxidative Stress | Administration, Oral | Humans | Male | Clinical Trials as Topic | Embryonic Development | Spermatozoa - metabolism | Pregnancy | Sperm Motility - drug effects | Antioxidants - therapeutic use | DNA Fragmentation | Antioxidants - administration & dosage | Female | Infertility, Male - metabolism | Pregnancy Outcome
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3. Full Text Antioxidants for male subfertility
by Smits, Roos M and Mackenzie-Proctor, Rebecca and Yazdani, Anusch and Stankiewicz, Marcin T and Jordan, Vanessa and Showell, Marian G
Cochrane Database of Systematic Reviews, ISSN 1469-493X, 03/2019, Volume 2019, Issue 3, p. CD007411
Background The inability to have children affects 10% to 15% of couples worldwide. A male factor is estimated to account for up to half of the infertility... 
Sperm Count | Oxidative Stress [drug effects] | L-ACETYL-CARNITINE | Humans | Spermatozoa [drug effects] | Male | CHROMATIN-STRUCTURE ASSAY | SEMINAL OXIDATIVE STRESS | Antioxidants [therapeutic use] | CONTROLLED CLINICAL-TRIAL | MEDICINE, GENERAL & INTERNAL | DNA Fragmentation | Abortion, Spontaneous [epidemiology] | Female | Pregnancy Rate | Infertility, Male [drug therapy etiology] | DEOXYRIBONUCLEIC-ACID DAMAGE | Live Birth | RANDOMIZED DOUBLE-BLIND | SPERM DNA FRAGMENTATION | Randomized Controlled Trials as Topic | Sperm Motility [drug effects] | Pregnancy | IDIOPATHIC MALE-INFERTILITY | POLYUNSATURATED FATTY-ACIDS | DNA Damage | COMBINED L-CARNITINE | Infertility, Male - drug therapy | Infertility, Male - etiology | Spermatozoa - drug effects | Sperm Motility - drug effects | Abortion, Spontaneous - epidemiology | Antioxidants - therapeutic use | Live Birth - epidemiology | Oxidative Stress - drug effects | Gastrointestinal Diseases - chemically induced
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4. Full Text Antioxidants for male subfertility
by Showell, Marian G and Brown, Julie and Yazdani, Anusch and Stankiewicz, Marcin T and Hart, Roger J
Cochrane database of systematic reviews (Online), ISSN 1469-493X, 2011, Volume 1, Issue 1, p. CD007411
Background Between 30% to 80% of male subfertility cases are considered to be due to the damaging effects of oxidative stress on sperm. Oral supplementation... 
MALE-INFERTILITY | MEDICINE, GENERAL & INTERNAL | L-ACETYL-CARNITINE | OXIDATIVE STRESS | VITAMIN-E | BLIND RANDOMIZED-TRIAL | ZINC-SULFATE | CHROMATIN-STRUCTURE ASSAY | SPERM DNA FRAGMENTATION | FOLIC-ACID | COMBINED L-CARNITINE | Infertility, Male - drug therapy | Sperm Count | Humans | Live Birth | Infertility, Male - etiology | Male | Spermatozoa - drug effects | Pregnancy | Sperm Motility - drug effects | Antioxidants - therapeutic use | Female | DNA Damage | Oxidative Stress - drug effects | Pregnancy Rate
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5. Full Text Empirical Drug Therapy for Idiopathic Male Infertility: What is the New Evidence?
by Garg, Harshit and Kumar, Rajeev
Urology, ISSN 0090-4295, 2015, Volume 86, Issue 6, pp. 1065 - 1075
Idiopathic male infertility is empirically managed using a number of drugs. We reviewed 64 articles published in the last 10 years on such drug therapy. There... 
Urology | SUPPLEMENTATION | L-CARNITINE | OXIDATIVE STRESS | IN-VITRO | NITRIC-OXIDE SYNTHASE | SEMINAL PLASMA | MEN | DOUBLE-BLIND | UROLOGY & NEPHROLOGY | ALPHA-TOCOPHEROL | SEMEN PARAMETERS | Infertility, Male - drug therapy | Glutathione - therapeutic use | Humans | Live Birth | Ubiquinone - analogs & derivatives | Male | Gonadotropins - therapeutic use | Pregnancy | Antioxidants - therapeutic use | Estrogen Receptor Modulators - therapeutic use | Carotenoids - therapeutic use | Carnitine - therapeutic use | Vitamin E - therapeutic use | Ubiquinone - therapeutic use | Female | Arginine - therapeutic use | Aromatase Inhibitors - therapeutic use | Pregnancy Rate | Drugs | Antioxidants | Drug therapy | Infertility, Male | Analysis
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6. Full Text Drug Therapy for Idiopathic Male Infertility: Rationale Versus Evidence
by Kumar, Rajeev and Gautam, Gagan and Gupta, Narmada P
The Journal of Urology, ISSN 0022-5347, 2006, Volume 176, Issue 4, pp. 1307 - 1312
About half of all infertile men who seek treatment have no specific cause that can be determined for the seminal abnormality. These men are often subject to a... 
drug therapy | testis | oligospermia | infertility | antioxidants | male | VITAMIN-E | OXIDATIVE STRESS | HUMAN SEMINAL FLUID | CLOMIPHENE CITRATE | PULSATILE LUTEINIZING-HORMONE | SEMEN QUALITY | INTRACYTOPLASMIC SPERM INJECTION | GLUTATHIONE THERAPY | DOUBLE-BLIND TRIAL | UROLOGY & NEPHROLOGY | FOLLICLE-STIMULATING-HORMONE | Infertility, Male - drug therapy | Antioxidants - therapeutic use | Vitamin B Complex - therapeutic use | Humans | Carnitine - therapeutic use | Hormones - therapeutic use | Male | Treatment Outcome | Antioxidants | Coenzymes | Follicle-stimulating hormone | Infertility | Luteinizing hormone | Glycoproteins | Hormones | Drug therapy
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7. Full Text Gonadotrophins for idiopathic male factor subfertility
by Attia, Abdelhamid M and Attia, Abdelhamid M and Abou-Setta, Ahmed M and Abou-Setta, Ahmed M and Al-Inany, Hesham G and Al-Inany, Hesham G
The Cochrane database of systematic reviews, ISSN 1469-493X, 2013, Volume 8, Issue 8, p. CD005071
Background Male factors leading to subfertility account for at least half of all cases of subfertility worldwide. Although some causes of male subfertility are... 
Follicle Stimulating Hormone [therapeutic use] | Oligospermia [drug therapy] | Humans | VACCINE | Male | Randomized Controlled Trials as Topic | ASSISTED REPRODUCTION | MEDICINE, GENERAL & INTERNAL | MALE-FACTOR INFERTILITY | THERAPY | DOUBLE-BLIND | Gonadotropins [therapeutic use] | FOLLICLE-STIMULATING-HORMONE | IN-VITRO FERTILIZATION | Infertility, Male [drug therapy] | Infertility, Male - drug therapy | Pregnancy | Follicle Stimulating Hormone - therapeutic use | Female | Birth Rate | Oligospermia - drug therapy | Gonadotropins - therapeutic use | Pregnancy Rate
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8. Full Text Empirical Medical Therapy for Idiopathic Male Infertility: A Survey of the American Urological Association
by Ko, Edmund Y and Siddiqi, Kashif and Brannigan, Robert E and Sabanegh, Edmund S
Journal of Urology, The, ISSN 0022-5347, 2012, Volume 187, Issue 3, pp. 973 - 978
Purpose We determined empirical medical therapy practice patterns for idiopathic infertility. Materials and Methods We performed a survey of 7,745 practicing... 
Urology | physician's practice patterns | testis | oligospermia | infertility | male | health care surveys | CONTROLLED-TRIAL | PLACEBO | EFFICACY | CLOMIPHENE CITRATE | MEN | infertility, male | UROLOGY & NEPHROLOGY | CROSSOVER | AZOOSPERMIA | Infertility, Male - drug therapy | Practice Patterns, Physicians' - statistics & numerical data | Urology - education | United States | Humans | Statistics, Nonparametric | Urology - methods | Male | Surveys and Questionnaires | Patient Selection | Surveys | Medical personnel | Training | Medical colleges | Follicle-stimulating hormone | Continuing medical education | Care and treatment | Medical societies | Infertility | Luteinizing hormone | Glycoproteins
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9. Full Text Insulin rescues impaired spermatogenesis via the hypothalamic-pituitary- gonadal axis in Akita diabetic mice and restores male fertility
by Schoeller, Erica L and Albanna, Gabriella and Frolova, Antonina I and Moley, Kelle H
Diabetes, ISSN 0012-1797, 07/2012, Volume 61, Issue 7, pp. 1869 - 1878
The mechanism responsible for poor reproductive outcomes in type 1 diabetic males is not well understood. In light of new evidence that the Sertoli cells of... 
Hypoglycemic Agents - therapeutic use | Infertility, Male - drug therapy | Hypothalamo-Hypophyseal System - drug effects | Spermatogenesis - drug effects | Luteinizing Hormone - blood | Male | Fertility Agents, Male - therapeutic use | Insulin - biosynthesis | Testis - drug effects | Organ Size - drug effects | Animals | Testis - pathology | Follicle Stimulating Hormone - blood | Testis - anatomy & histology | Mice | Testosterone - blood | Insulin - therapeutic use | Physiological aspects | Research | Spermatogenesis | Insulin | Analysis | Complications
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