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1. Full Text NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis
by Hirota, Simon A and Ng, Jeffrey and Lueng, Alan and Khajah, Maitham and Parhar, Ken and Li, Yan and Lam, Victor and Potentier, Mireille S and Ng, Kelvin and Bawa, Misha and McCafferty, Donna‐Marie and Rioux, Kevin P and Ghosh, Subrata and Xavier, Ramnik J and Colgan, Sean P and Tschopp, Jurg and Muruve, Daniel and MacDonald, Justin A and Beck, Paul L
Inflammatory bowel diseases, ISSN 1078-0998, 06/2011, Volume 17, Issue 6, pp. 1359 - 1372
microbiota | NLRP3 | neutrophil | inflammasome | defensin | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Carrier Proteins - physiology | Interleukin-1beta - physiology | NLR Family, Pyrin Domain-Containing 3 Protein | Transforming Growth Factor beta - physiology | Interleukin-10 - physiology | Inflammasomes - physiology | Animals | Chemotaxis - physiology | Colitis - physiopathology | Thiophenes | Immunity, Innate - physiology | Homeostasis - physiology | Furans | Mice | Apoptosis - physiology | Intestines - physiology | Disease Models, Animal | Animal models | Inflammatory bowel diseases | Immune response | muramyl dipeptide | Homeostasis | Antimicrobial agents | Data processing | Crohn's disease | Leukocytes (neutrophilic) | Macrophages | Secretions | Chemotaxis | Interleukin 18 | Sodium | Intestine | Interleukin 10 | Dextran sulfate | Colitis | Intestinal microflora | Mutation | Growth factors | Apoptosis | Immune system | Index Medicus
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2. Full Text Differential requirement for caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing
by Broz, Petr and Von Moltke, Jakob and Jones, Jonathan W and Vance, Russell E and Monack, Denise M
Cell host & microbe, ISSN 1931-3128, 12/2010, Volume 8, Issue 6, pp. 471 - 483
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Pseudomonas aeruginosa - physiology | Cytokines - physiology | Cell Death | Caspase 1 - physiology | Cytoskeletal Proteins - physiology | Macrophages - microbiology | DNA-Binding Proteins | Protein Structure, Tertiary | Cell Line | Salmonella typhimurium - physiology | CARD Signaling Adaptor Proteins - physiology | Macrophages - pathology | Mice, Inbred C57BL | Nuclear Proteins - metabolism | Inflammasomes - physiology | Macrophages - metabolism | Animals | Bacterial Infections - pathology | Caspase 1 - genetics | Calcium-Binding Proteins - physiology | Francisella - physiology | Apoptosis Regulatory Proteins - physiology | Legionella pneumophila - physiology | Mice | Bacterial Infections - metabolism | Cysteine | Biochemistry | Interleukins | Macrophages | Cell death | Proteases | Index Medicus
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3. Full Text Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles
by Rothmeier, Andrea S and Marchese, Patrizia and Petrich, Brian G and Furlan-Freguia, Christian and Ginsberg, Mark H and Ruggeri, Zaverio M and Ruf, Wolfram
The Journal of clinical investigation, ISSN 0021-9738, 04/2015, Volume 125, Issue 4, pp. 1471 - 1484
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Macrophages - physiology | Thrombosis - physiopathology | Mice, Inbred C57BL | Immunity, Innate | Receptors, Purinergic P2X7 - physiology | Inflammasomes - physiology | Animals | Extracellular Fluid | Cell-Derived Microparticles - physiology | Signal Transduction - physiology | Membrane Microdomains - physiology | Mice | Thioredoxin-Disulfide Reductase - physiology | Thioredoxins - physiology | Caspase 1 - physiology | Pseudopodia - physiology | Adenosine Triphosphate - physiology | Actins - physiology | Inflammation - physiopathology | Development and progression | Cellular signal transduction | Genetic aspects | Health aspects | Thrombosis | Blood clot | Statistical analysis | Cytokines | Pathogenesis | Molecular weight | Proteins | Microscopy | Atherosclerosis | Ligands | Software | Life sciences | Scientific imaging | Labeling | Mass spectrometry | Index Medicus | Abridged Index Medicus
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4. Full Text Infections, atherosclerosis, and coronary heart disease
by Pothineni, Naga Venkata K and Subramany, Swathi and Kuriakose, Kevin and Shirazi, Lily F and Romeo, Francesco and Shah, Prediman K and Mehta, Jawahar L
European heart journal, ISSN 0195-668X, 2017, Volume 38, Issue 43, pp. 3195 - 3201
Infection | Atherosclerosis | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Atherosclerosis - drug therapy | Molecular Mimicry - physiology | Humans | Vaccination | Cell Proliferation - physiology | Anti-Infective Agents - therapeutic use | Coronary Disease - etiology | Leukocytes - physiology | Cell Movement - physiology | Cytokines - physiology | Disease Progression | Endothelium, Vascular - physiology | Plaque, Atherosclerotic - etiology | Rupture, Spontaneous - etiology | Atherosclerosis - etiology | Inflammasomes - physiology | Animals | Heat-Shock Proteins - physiology | Chronic Disease | Atherosclerosis - prevention & control | Infection - complications | Lipid Metabolism - physiology | Disease Models, Animal | Index Medicus
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5. Metabolic signals and innate immune activation in obesity and exercise
by Ringeis, Robert and Ringseis, Robert and Eder, Klaus and Eder, Klaus and Mooren, Frank C and Mooren, Frank C and Krüger, Karsten and Krüger, Karsten
Exercise immunology review, ISSN 1077-5552, 2015, Volume 21, pp. 58 - 68
adipose tissue | immune system | exercise | fatty acids | inflammation | obesity | Immunology | Sport Sciences | Life Sciences & Biomedicine | Science & Technology | Motor Activity - physiology | Diet - adverse effects | Obesity - immunology | Physical Exertion - physiology | Humans | Receptors, Pattern Recognition - physiology | I-kappa B Proteins - physiology | Sedentary Lifestyle | Adipose Tissue - immunology | Exercise Therapy | Adipose Tissue - metabolism | Inflammation - metabolism | Fatty Acids, Nonesterified - blood | Inflammation Mediators - physiology | Receptors, G-Protein-Coupled - physiology | Carrier Proteins - physiology | Macrophages - physiology | NF-KappaB Inhibitor alpha | Inflammation Mediators - blood | Inflammation - immunology | Fatty Acids, Nonesterified - toxicity | Unfolded Protein Response | Inflammation - etiology | Mice, Knockout | Obesity - metabolism | Inflammasomes - physiology | Animals | Obesity - epidemiology | NF-kappa B - physiology | Obesity - therapy | Signal Transduction - physiology | Exercise - physiology
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6. Full Text Inflammasomes: current understanding and open questions
by Bauernfeind, Franz and Bauernfeind, Franz and Ablasser, Andrea and Ablasser, Andrea and Bartok, Eva and Bartok, Eva and Kim, Sarah and Kim, Sarah and Schmid-Burgk, Jonathan and Schmid-Burgk, Jonathan and Cavlar, Taner and Cavlar, Taner and Hornung, Veit and Hornung, Veit
Cellular and molecular life sciences : CMLS, ISSN 1420-682X, 3/2011, Volume 68, Issue 5, pp. 765 - 783
Life Sciences | Biochemistry, general | AIM2 | Life Sciences, general | NLR | NLRP3 | IL-1β | Biomedicine general | Cell Biology | Caspase-1 | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Adaptor Proteins, Signal Transducing - chemistry | Calcium-Binding Proteins - chemistry | Carrier Proteins - physiology | Interleukin-1beta - physiology | CARD Signaling Adaptor Proteins - physiology | Signal Transduction | NLR Family, Pyrin Domain-Containing 3 Protein | Apoptosis Regulatory Proteins - chemistry | Humans | Caspase 1 - metabolism | Immunity, Innate | Nuclear Proteins - chemistry | Inflammasomes - physiology | Adaptor Proteins, Signal Transducing - physiology | Models, Immunological | Interleukin-1beta - metabolism | Calcium-Binding Proteins - physiology | CARD Signaling Adaptor Proteins - chemistry | Apoptosis Regulatory Proteins - physiology | Carrier Proteins - chemistry | Nuclear Proteins - physiology | DNA-Binding Proteins | Proteins | Signal transduction | Cellular biology | Rodents | Molecular biology | Gene expression | Immune system | Index Medicus
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7. Full Text XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation
by Yabal, Monica and Müller, Nicole and Adler, Heiko and Knies, Nathalie and Groß, Christina J and Damgaard, Rune Busk and Kanegane, Hirokazu and Ringelhan, Marc and Kaufmann, Thomas and Heikenwälder, Mathias and Strasser, Andreas and Groß, Olaf and Ruland, Jürgen and Peschel, Christian and Gyrd-Hansen, Mads and Jost, Philipp J
Cell reports (Cambridge), ISSN 2211-1247, 06/2014, Volume 7, Issue 6, pp. 1796 - 1808
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Tumor Necrosis Factor-alpha - metabolism | Inflammasomes - metabolism | Tumor Necrosis Factor-alpha - genetics | Dendritic Cells - physiology | Male | Interleukin-1beta - genetics | Inflammasomes - drug effects | Interleukin-1beta - metabolism | Dendritic Cells - drug effects | Female | Interleukin-1beta - physiology | Mice, Transgenic | Inflammasomes - genetics | Receptor-Interacting Protein Serine-Threonine Kinases - physiology | X-Linked Inhibitor of Apoptosis Protein - genetics | Inflammasomes - physiology | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Cell Death - physiology | Lipopolysaccharides - pharmacology | Tumor Necrosis Factor-alpha - physiology | X-Linked Inhibitor of Apoptosis Protein - metabolism | Dendritic Cells - cytology | Mice | Apoptosis - physiology | X-Linked Inhibitor of Apoptosis Protein - physiology | Index Medicus
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