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1. Full Text Oseltamivir-resistant influenza virus A (H1N1), Europe, 2007-08 season
by Meijer, A and Lackenby, A and Hungnes, O and Lina, B and Werf, S. van der and Schweiger, B and Opp, M and Paget, J and Kassteele, J. van de and Hay, A and Zambon, M and European Influenza Surveillance Scheme and on behalf of the European Influenza Surveillance Scheme
Emerging infectious diseases, ISSN 1080-6040, 2009, Volume 15, Issue 4, pp. 552 - 560
Antiviral Agents - pharmacology | Influenza A Virus, H1N1 Subtype - classification | Hemagglutinins, Viral - genetics | Humans | Enzyme Inhibitors - pharmacology | Europe - epidemiology | Neuraminidase - genetics | Influenza, Human - epidemiology | Communicable Diseases, Emerging - epidemiology | Phylogeny | Influenza A Virus, H1N1 Subtype - drug effects | Drug Resistance, Viral - genetics | Influenza A Virus, H1N1 Subtype - enzymology | Genes, Viral | Communicable Diseases, Emerging - drug therapy | Influenza, Human - virology | Neuraminidase - antagonists & inhibitors | Influenza, Human - drug therapy | Mutation | Seasons | Communicable Diseases, Emerging - virology | Influenza A Virus, H1N1 Subtype - genetics | Oseltamivir - pharmacology | Population Surveillance - methods | Influenza viruses | Causes of | Research | Health aspects | Influenza | Distribution | Index Medicus | Life Sciences | Biochemistry, Molecular Biology
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2. Full Text In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses
by Shinya, Kyoko and Suresh, M and Fujii, Ken and Mitamura, Keiko and Makino, Akiko and Imai, Hirotaka and Ozawa, Makoto and Kawaoka, Yoshihiro and Saito, Reiko and Sakoda, Yoshihiro and Murakami, Shin and Itoh, Yasushi and Sakai-Tagawa, Yuko and Yamazaki, Masahiko and Tamura, Daisuke and Muramoto, Yukiko and Okamatsu, Masatoshi and Nakamura, Morio and Kida, Hiroshi and Neumann, Gabriele and Noda, Takeshi and Ishigaki, Hirohito and Imai, Masaki and Ito, Mutsumi and Shult, Peter A and Furuta, Yousuke and Gern, James and Shimojima, Masayuki and Sakabe, Saori and Horimoto, Taisuke and Kakugawa, Satoshi and Takahashi, Kazuo and Hatta, Yasuko and Warshauer, David and Li, Chengjun and Watanabe, Tokiko and Takahashi, Kei and Suzuki, Hiroshi and Ogasawara, Kazumasa and Sugaya, Norio and Watanabe, Shinji and Goto, Hideo and Brockman-Schneider, Rebecca and Yamada, Shinya and Hatta, Masato and Kiso, Maki and Mitamura, Hiroshi and Iwatsuki-Horimoto, Kiyoko and Nakano, Kunio and Takano, Ryo and Nakayama, Misako and Yamashita, Makoto
Nature (London), ISSN 0028-0836, 08/2009, Volume 460, Issue 7258, pp. 1021 - 1025
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains | Antiviral agents | Microbiology | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Virology | Antibiotics. Antiinfectious agents. Antiparasitic agents | Macaca fascicularis - immunology | Swine Diseases - virology | Humans | Influenza A Virus, H1N1 Subtype - physiology | Male | Neutralization Tests | Ferrets - virology | Swine, Miniature - virology | Lung - virology | Primate Diseases - pathology | Female | Cell Line | Antiviral Agents - pharmacology | Lung - pathology | Swine Diseases - pathology | Influenza A Virus, H1N1 Subtype - pathogenicity | HN Protein - metabolism | Influenza A Virus, H1N1 Subtype - drug effects | Primate Diseases - virology | Animals | Orthomyxoviridae Infections - transmission | Virus Replication | Influenza A Virus, H1N1 Subtype - enzymology | Dogs | Antibodies, Viral - immunology | Mice | Mice, Inbred BALB C | Orthomyxoviridae Infections - virology | Swine - virology | Lung - immunology | Macaca fascicularis - virology | Orthomyxoviridae Infections - immunology | Influenza viruses | Genetic aspects | Properties | Swine influenza | Scanning electron microscopy | Cytokines | Swine flu | Influenza | Viruses | Avian flu | Index Medicus
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3. Full Text Cross-reactive neuraminidase-inhibiting antibodies elicited by immunization with recombinant neuraminidase proteins of H5N1 and pandemic H1N1 influenza A viruses
by Liu, Wen-Chun and Lin, Chia-Ying and Tsou, Yung-Ta and Jan, Jia-Tsrong and Wu, Suh-Chin
Journal of virology, ISSN 0022-538X, 2015, Volume 89, Issue 14, pp. 7224 - 7234
Life Sciences & Biomedicine | Science & Technology | Virology | Influenza A Virus, H1N1 Subtype - immunology | Influenza A Virus, H5N1 Subtype - enzymology | Orthomyxoviridae Infections - prevention & control | Influenza Vaccines - administration & dosage | Influenza A Virus, H5N1 Subtype - genetics | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Vaccines, Synthetic - immunology | Antibodies, Viral - blood | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Influenza A Virus, H7N9 Subtype - immunology | Spodoptera | Sf9 Cells | Baculoviridae | Female | Influenza A Virus, H1N1 Subtype - genetics | Disease Models, Animal | Vaccines, Synthetic - genetics | Recombinant Proteins - genetics | Influenza A Virus, H3N2 Subtype - immunology | Cross Reactions | Animals | Influenza Vaccines - immunology | Influenza Vaccines - genetics | Recombinant Proteins - immunology | Influenza A Virus, H1N1 Subtype - enzymology | Influenza A Virus, H5N1 Subtype - immunology | Mice, Inbred BALB C | Vaccines, Synthetic - administration & dosage | Genetic Vectors | Orthomyxoviridae Infections - virology | Index Medicus
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4. Full Text The PB2 Subunit of the Influenza Virus RNA Polymerase Affects Virulence by Interacting with the Mitochondrial Antiviral Signaling Protein and Inhibiting Expression of Beta Interferon
by Katy M. Graef and Frank T. Vreede and Yuk-Fai Lau and Amber W. McCall and Simon M. Carr and Kanta Subbarao and Ervin Fodor
Journal of Virology, ISSN 0022-538X, 09/2010, Volume 84, Issue 17, pp. 8433 - 8445
Life Sciences & Biomedicine | Science & Technology | Virology | Influenza A Virus, H5N1 Subtype - enzymology | Influenza A Virus, H2N2 Subtype - enzymology | Humans | Influenza A virus - genetics | RNA Replicase - metabolism | Virulence | Molecular Sequence Data | Influenza A Virus, H5N1 Subtype - genetics | Viral Proteins - metabolism | Influenza A virus - pathogenicity | Interferon-beta - genetics | Female | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Amino Acid Sequence | Influenza, Human - metabolism | RNA Replicase - genetics | Viral Proteins - chemistry | Down-Regulation | Mice, Inbred C57BL | Viral Proteins - genetics | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza A Virus, H2N2 Subtype - pathogenicity | Influenza A virus - enzymology | Host-Pathogen Interactions | Sequence Alignment | Animals | Interferon-beta - metabolism | Influenza A Virus, H1N1 Subtype - enzymology | RNA Replicase - chemistry | Influenza, Human - genetics | Adaptor Proteins, Signal Transducing - genetics | Influenza A Virus, H2N2 Subtype - genetics | Protein Binding | Influenza A Virus, H5N1 Subtype - pathogenicity | Mice | Adaptor Proteins, Signal Transducing - metabolism | Index Medicus | Cellular Response to Infection
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5. Full Text Oseltamivir-resistant influenza A(H1N1) pdm09 viruses, United States, 2013–14
by Okomo-Adhiambo, Margaret and Fry, Alicia M and Su, Su and Nguyen, Ha T and Elal, Anwar Abd and Negron, Elizabeth and Hand, Julie and Garten, Rebecca J and Barnes, John and Xiyan, Xu and Villanueva, Julie M and Gubareva, Larisa V and 2013-14 US Influenza Antiviral and 2013–14 US Influenza Antiviral Working Group
Emerging infectious diseases, ISSN 1080-6040, 2015, Volume 21, Issue 1, pp. 136 - 141
Infectious Diseases | Immunology | Life Sciences & Biomedicine | Science & Technology | United States - epidemiology | Antiviral Agents - pharmacology | Prevalence | Humans | Middle Aged | Drug Resistance, Viral | Neuraminidase - genetics | Viral Proteins - genetics | Influenza, Human - epidemiology | Male | Phylogeny | Influenza A Virus, H1N1 Subtype - drug effects | Young Adult | Influenza A Virus, H1N1 Subtype - enzymology | Adolescent | Adult | Female | Influenza, Human - virology | Influenza, Human - drug therapy | Influenza A Virus, H1N1 Subtype - genetics | Oseltamivir - pharmacology | Avian influenza | Oseltamivir phosphate | United States | Patient outcomes | Medical care | Forecasts and trends | Drug therapy | Index Medicus | influenza | influenza A(H1N1)pdm09 viruses | viruses | neuraminidase inhibition | Dispatch | pyrosequencing | resistance | Oseltamivir-Resistant Influenza A(H1N1)pdm09 Viruses, United States, 2013–14 | H275Y mutation | neuraminidase | influenza virus | zanamivir | oseltamivir
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6. Full Text Impact of the Baloxavir-Resistant Polymerase Acid I38T Substitution on the Fitness of Contemporary Influenza A(H1N1)pdm09 and A(H3N2) Strains
by Checkmahomed, Liva and M’hamdi, Zeineb and Carbonneau, Julie and Venable, Marie-Christine and Baz, Mariana and Abed, Yacine and Boivin, Guy
The Journal of infectious diseases, ISSN 0022-1899, 01/2020, Volume 221, Issue 1, pp. 63 - 70
Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Thiepins - therapeutic use | Triazines - therapeutic use | Thiepins - pharmacology | Influenza A Virus, H3N2 Subtype - genetics | Viral Proteins - metabolism | Lung - virology | Madin Darby Canine Kidney Cells | Inhibitory Concentration 50 | Female | Influenza A Virus, H1N1 Subtype - genetics | Orthomyxoviridae Infections - drug therapy | Oxazines - pharmacology | Pyridines - therapeutic use | Virus Replication - drug effects | Antiviral Agents - pharmacology | Triazines - pharmacology | Influenza A Virus, H3N2 Subtype - enzymology | RNA-Dependent RNA Polymerase - genetics | Antiviral Agents - therapeutic use | Influenza A Virus, H3N2 Subtype - pathogenicity | Mice, Inbred C57BL | Pyridones | RNA-Dependent RNA Polymerase - metabolism | Viral Proteins - genetics | Influenza A Virus, H1N1 Subtype - pathogenicity | Morpholines | Drug Resistance, Viral - genetics | Phenotype | Animals | Influenza A Virus, H1N1 Subtype - enzymology | Oxazines - therapeutic use | Dogs | Dibenzothiepins | Mice | Pyridines - pharmacology | Mutation | Viral Load - drug effects | Orthomyxoviridae Infections - virology | Amino Acid Substitution | Polymerase chain reaction | Oseltamivir | Cell culture | Influenza | Virulence | Viruses | Influenza A | Experiments | Fitness | Mutants | Index Medicus | Abridged Index Medicus | influenza | Major and Brief Reports | A(H3N2) | I38T | A(H1N1)pdm09 | baloxavir | resistance
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7. Full Text Surveillance for Neuraminidase Inhibitor Resistance among Human Influenza A and B Viruses Circulating Worldwide from 2004 to 2008
by Tiffany G. Sheu and Varough M. Deyde and Margaret Okomo-Adhiambo and Rebecca J. Garten and Xiyan Xu and Rick A. Bright and Eboneé N. Butler and Teresa R. Wallis and Alexander I. Klimov and Larisa V. Gubareva
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 09/2008, Volume 52, Issue 9, pp. 3284 - 3292
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Viral diseases of the respiratory system and ent viral diseases | Infectious diseases | Pharmacology. Drug treatments | Viral diseases | Biological and medical sciences | Medical sciences | Human viral diseases | Antibiotics. Antiinfectious agents. Antiparasitic agents | Cell Line | Influenza B virus - enzymology | Antiviral Agents - pharmacology | Influenza A Virus, H3N2 Subtype - enzymology | Global Health | Influenza A Virus, H3N2 Subtype - drug effects | Antiviral Agents - therapeutic use | Oseltamivir - therapeutic use | Humans | Drug Resistance, Viral | Neuraminidase - genetics | Influenza, Human - epidemiology | Influenza A Virus, H3N2 Subtype - genetics | Influenza A Virus, H1N1 Subtype - drug effects | Influenza B virus - genetics | Animals | Influenza A Virus, H1N1 Subtype - enzymology | Influenza, Human - virology | Neuraminidase - antagonists & inhibitors | Influenza B virus - drug effects | Seasons | Influenza A Virus, H1N1 Subtype - genetics | Population Surveillance | Oseltamivir - pharmacology | Index Medicus | Antiviral Agents
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8. Full Text The PB1 segment of an influenza A virus H1N1 2009pdm isolate enhances the replication efficiency of specific influenza vaccine strains in cell culture and embryonated eggs
by Mostafa, Ahmed and Kanrai, Pumaree and Ziebuhr, John and Pleschka, Stephan
Journal of general virology, ISSN 0022-1317, 03/2016, Volume 97, Issue 3, pp. 620 - 631
Influenza A Virus, H1N1 Subtype - immunology | Influenza A Virus, H7N9 Subtype - physiology | Influenza Vaccines - administration & dosage | Influenza A Virus, H5N1 Subtype - physiology | Humans | Influenza A Virus, H1N1 Subtype - physiology | Influenza A Virus, H5N1 Subtype - genetics | Ovum - virology | Influenza A Virus, H3N2 Subtype - genetics | Viral Proteins - metabolism | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Influenza A Virus, H9N2 Subtype - genetics | Viral Proteins - genetics | Influenza, Human - epidemiology | Chick Embryo | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Animals | Influenza Vaccines - immunology | Influenza Vaccines - genetics | Virus Replication | Influenza A Virus, H1N1 Subtype - enzymology | Influenza A Virus, H3N2 Subtype - physiology | Influenza A Virus, H7N9 Subtype - genetics | Influenza, Human - prevention & control | Influenza A Virus, H9N2 Subtype - physiology | Index Medicus
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9. Full Text Functional Balance of the Hemagglutinin and Neuraminidase Activities Accompanies the Emergence of the 2009 H1N1 Influenza Pandemic
by Rui Xu and Xueyong Zhu and Ryan McBride and Corwin M. Nycholat and Wenli Yu and James C. Paulson and Ian A. Wilson
Journal of Virology, ISSN 0022-538X, 09/2012, Volume 86, Issue 17, pp. 9221 - 9232
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | Pandemics | Receptors, Virus - metabolism | Swine Diseases - virology | Humans | Neuraminidase - genetics | Viral Proteins - metabolism | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Swine | Neuraminidase - chemistry | Polysaccharides - chemistry | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Influenza A Virus, H1N1 Subtype - metabolism | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Influenza, Human - metabolism | Orthomyxoviridae Infections - metabolism | Orthomyxoviridae Infections - veterinary | Viral Proteins - chemistry | Swine Diseases - metabolism | Neuraminidase - metabolism | Viral Proteins - genetics | Influenza, Human - epidemiology | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Polysaccharides - metabolism | Animals | Receptors, Virus - chemistry | Influenza A Virus, H1N1 Subtype - enzymology | Protein Binding | Kinetics | Orthomyxoviridae Infections - virology | Index Medicus | Virus-Cell Interactions
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10. Full Text Antiviral activity of baicalin against influenza A (H1N1/H3N2) virus in cell culture and in mice and its inhibition of neuraminidase
by Ding, Yue and Dou, Jie and Teng, Zaijin and Yu, Jie and Wang, Tingting and Lu, Na and Wang, Hui and Zhou, Changlin
Archives of virology, ISSN 0304-8608, 12/2014, Volume 159, Issue 12, pp. 3269 - 3278
Medical Microbiology | Infectious Diseases | Biomedicine | Virology | Life Sciences & Biomedicine | Science & Technology | Influenza A Virus, H3N2 Subtype - drug effects | Influenza A Virus, H1N1 Subtype - physiology | Flavonoids - therapeutic use | Microbial Sensitivity Tests | Lung - virology | Madin Darby Canine Kidney Cells | Inhibitory Concentration 50 | Flavonoids - pharmacology | Cell Culture Techniques | Orthomyxoviridae Infections - drug therapy | Disease Models, Animal | Antiviral Agents - pharmacology | Lung - pathology | Influenza A Virus, H3N2 Subtype - enzymology | Antiviral Agents - therapeutic use | Enzyme Inhibitors - pharmacology | Treatment Outcome | Viral Proteins - antagonists & inhibitors | Influenza A Virus, H1N1 Subtype - drug effects | Enzyme Inhibitors - therapeutic use | Enzyme Inhibitors - isolation & purification | Virus Release - drug effects | Administration, Intravenous | Animals | Influenza A Virus, H1N1 Subtype - enzymology | Dogs | Survival Analysis | Neuraminidase - antagonists & inhibitors | Scutellaria - chemistry | Flavonoids - isolation & purification | Influenza A Virus, H3N2 Subtype - physiology | Mice | Antiviral Agents - isolation & purification | Antiviral agents | Dosage and administration | Health aspects | Analysis | Mortality | Influenza | Index Medicus
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11. Full Text Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants
by Martin, Stephen R and Gamblin, Steven J and Collins, Patrick J and Skehel, John J and Lin, Yi Pu and Hay, Alan J and Russell, Rupert J and Haire, Lesley F and Walker, Philip A and Liu, Junfeng
Nature (London), ISSN 0028-0836, 06/2008, Volume 453, Issue 7199, pp. 1258 - 1261
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antiviral agents | Biological and medical sciences | Medical sciences | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Influenza A Virus, H5N1 Subtype - enzymology | Humans | Molecular Conformation | Drug Resistance, Viral | Neuraminidase - genetics | Crystallography, X-Ray | Influenza A Virus, H5N1 Subtype - genetics | Oseltamivir - chemistry | Enzyme Inhibitors - chemistry | Neuraminidase - chemistry | Influenza, Human - virology | Binding Sites | Influenza A Virus, H1N1 Subtype - genetics | Oseltamivir - pharmacology | Enzyme Inhibitors - metabolism | Enzyme Inhibitors - pharmacology | Models, Molecular | Neuraminidase - metabolism | Zanamivir - pharmacology | Influenza A Virus, H5N1 Subtype - drug effects | Influenza A Virus, H1N1 Subtype - drug effects | Mutation - genetics | Oseltamivir - metabolism | Influenza A Virus, H1N1 Subtype - enzymology | Protein Binding | Neuraminidase - antagonists & inhibitors | Kinetics | Influenza viruses | Properties | Microbial mutation | Proteins | Enzymes | Hydrogen bonds | Amino acids | Mutation | Drug resistance | Avian flu | Crystal structure | Index Medicus
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