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1. Full Text Recombinant influenza virus with a pandemic H2N2 polymerase complex has a higher adaptive potential than one with seasonal H2N2 polymerase complex
by Chin, Alex W. H and Yen, Hui Ling and Krauss, Scott and Webby, Richard J and Poon, Leo L. M
Journal of general virology, ISSN 0022-1317, 03/2016, Volume 97, Issue 3, pp. 611 - 619
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Virology | United States - epidemiology | Influenza A Virus, H2N2 Subtype - enzymology | Influenza A Virus, H3N2 Subtype - enzymology | Pandemics | RNA Replicase - genetics | Reassortant Viruses - enzymology | Humans | RNA Replicase - metabolism | Reassortant Viruses - genetics | Viral Proteins - genetics | Influenza, Human - epidemiology | Influenza A Virus, H3N2 Subtype - genetics | Viral Proteins - metabolism | Animals | Recombination, Genetic | Influenza A Virus, H2N2 Subtype - genetics | Influenza, Human - virology | Mutation | Seasons | Index Medicus | Standard
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2. Full Text The PB2 Subunit of the Influenza Virus RNA Polymerase Affects Virulence by Interacting with the Mitochondrial Antiviral Signaling Protein and Inhibiting Expression of Beta Interferon
by Katy M. Graef and Frank T. Vreede and Yuk-Fai Lau and Amber W. McCall and Simon M. Carr and Kanta Subbarao and Ervin Fodor
Journal of Virology, ISSN 0022-538X, 09/2010, Volume 84, Issue 17, pp. 8433 - 8445
Life Sciences & Biomedicine | Science & Technology | Virology | Influenza A Virus, H5N1 Subtype - enzymology | Influenza A Virus, H2N2 Subtype - enzymology | Humans | Influenza A virus - genetics | RNA Replicase - metabolism | Virulence | Molecular Sequence Data | Influenza A Virus, H5N1 Subtype - genetics | Viral Proteins - metabolism | Influenza A virus - pathogenicity | Interferon-beta - genetics | Female | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Amino Acid Sequence | Influenza, Human - metabolism | RNA Replicase - genetics | Viral Proteins - chemistry | Down-Regulation | Mice, Inbred C57BL | Viral Proteins - genetics | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza A Virus, H2N2 Subtype - pathogenicity | Influenza A virus - enzymology | Host-Pathogen Interactions | Sequence Alignment | Animals | Interferon-beta - metabolism | Influenza A Virus, H1N1 Subtype - enzymology | RNA Replicase - chemistry | Influenza, Human - genetics | Adaptor Proteins, Signal Transducing - genetics | Influenza A Virus, H2N2 Subtype - genetics | Protein Binding | Influenza A Virus, H5N1 Subtype - pathogenicity | Mice | Adaptor Proteins, Signal Transducing - metabolism | Index Medicus | Cellular Response to Infection
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3. Full Text A 27-Amino-Acid Deletion in the Neuraminidase Stalk Supports Replication of an Avian H2N2 Influenza A Virus in the Respiratory Tract of Chickens
by Erin M. Sorrell and Haichen Song and Lindomar Pena and Daniel R. Perez
Journal of Virology, ISSN 0022-538X, 11/2010, Volume 84, Issue 22, pp. 11831 - 11840
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | Cell Line | Sequence Deletion | Coturnix | Influenza A Virus, H2N2 Subtype - enzymology | Molecular Sequence Data | Neuraminidase - genetics | Neuraminidase - metabolism | Viral Proteins - genetics | Poultry Diseases - virology | Quail | Viral Proteins - metabolism | Respiratory System - virology | Animals | Virus Replication | Chickens | Influenza A Virus, H2N2 Subtype - genetics | Influenza in Birds - virology | Influenza A Virus, H2N2 Subtype - physiology | Index Medicus | Pathogenesis and Immunity
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4. Full Text Deletions in the Neuraminidase Stalk Region of H2N2 and H9N2 Avian Influenza Virus Subtypes Do Not Affect Postinfluenza Secondary Bacterial Pneumonia
by Ashok K. Chockalingam and Danielle Hickman and Lindomar Pena and Jianqiang Ye and Andrea Ferrero and Jose R. Echenique and Hongjun Chen and Troy Sutton and Daniel R. Perez
Journal of Virology, ISSN 0022-538X, 04/2012, Volume 86, Issue 7, pp. 3564 - 3573
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | Lung - microbiology | Influenza A Virus, H2N2 Subtype - enzymology | Humans | Influenza A Virus, H2N2 Subtype - chemistry | Neuraminidase - genetics | Influenza, Human - complications | Viral Proteins - metabolism | Influenza A Virus, H9N2 Subtype - chemistry | Lung - virology | Gene Deletion | Neuraminidase - chemistry | Female | Influenza, Human - virology | Influenza A Virus, H9N2 Subtype - enzymology | Streptococcus pneumoniae - physiology | Cell Line | Pneumonia, Bacterial - microbiology | Influenza A Virus, H9N2 Subtype - genetics | Viral Proteins - chemistry | Pneumonia, Bacterial - complications | Neuraminidase - metabolism | Viral Proteins - genetics | Coinfection - virology | Amino Acid Motifs | Bacterial Adhesion | Coinfection - microbiology | Animals | Chickens | Influenza A Virus, H2N2 Subtype - genetics | Influenza in Birds - virology | Mice | Mice, Inbred BALB C | Index Medicus | Pathogenesis and Immunity
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5. Full Text Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding
by Wu, Yan and Qin, Guangrong and Gao, Feng and Liu, Yue and Vavricka, Christopher J and Qi, Jianxun and Jiang, Hualiang and Yu, Kunqian and Gao, George F
Scientific reports, ISSN 2045-2322, 2013, Volume 3, Issue 1, pp. 1551 - 1551
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Oseltamivir - analogs & derivatives | Amino Acid Sequence | Influenza A Virus, H2N2 Subtype - enzymology | Influenza A Virus, H3N2 Subtype - enzymology | Protein Conformation - drug effects | Neuraminidase - genetics | Molecular Dynamics Simulation | Influenza A Virus, H1N1 Subtype - enzymology | Computer Simulation | Drug Design | Neuraminidase - chemistry | Neuraminidase - antagonists & inhibitors | Oseltamivir - pharmacology | Oseltamivir | Pandemics | Enzymatic activity | Influenza | Exo-a-sialidase | Influenza A | Drug development | Index Medicus
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6. Full Text The role of RNA folding free energy in the evolution of the polymerase genes of the influenza A virus
by Brower-Sinning, Rachel and Carter, Donald M and Crevar, Corey J and Ghedin, Elodie and Ross, Ted M and Benos, Panayiotis V
Genome Biology, ISSN 1474-7596, 02/2009, Volume 10, Issue 2, pp. R18 - R18
Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Influenza A Virus, H3N2 Subtype | Temperature | RNA Replicase - genetics | Humans | Influenza A virus - genetics | Influenza A Virus, H2N2 Subtype | Viral Proteins - genetics | Birds | Influenza A Virus, H5N1 Subtype | Influenza A virus - enzymology | RNA Stability | RNA, Viral - physiology | Thermodynamics | Animals | RNA, Viral - chemistry | Virus Replication | Influenza A Virus, H1N1 Subtype | Nucleic Acid Conformation | Evolution, Molecular | Index Medicus | Research
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7. Full Text Mutation-Induced Loop Opening and Energetics for Binding of Tamiflu to Influenza N8 Neuraminidase
by Kar, Parimal and Knecht, Volker
The journal of physical chemistry. B, ISSN 1520-6106, 05/2012, Volume 116, Issue 21, pp. 6137 - 6149
Physical Sciences | Chemistry | Chemistry, Physical | Science & Technology | Influenza A Virus, H5N1 Subtype - enzymology | Catalytic Domain | Influenza A Virus, H2N2 Subtype - enzymology | Enzyme Stability | Neuraminidase - genetics | Neuraminidase - metabolism | Antiviral Agents - metabolism | Influenza A virus - enzymology | Molecular Dynamics Simulation | Oseltamivir - metabolism | Thermodynamics | Influenza A Virus, H1N1 Subtype - enzymology | Neuraminidase - chemistry | Water - chemistry | Protein Binding | Mutation | Oseltamivir phosphate | Usage | Helix-loop-helix motif | Poisson ratio | Microbial mutation | Enzyme binding | Research | Structure | Index Medicus | Drugs | Mutations | Computer simulation | Mathematical analysis | Influenza | Binding energy | Affinity | Free energy
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8. Full Text Location on the evolutionary trees of the non-structural protein (NS) and neuraminidase (NA) genes of late human influenza A (H2N2) viruses: parental viruses of the NS and NA genes of Hong Kong influenza A (H3N2) viruses
by Nakao, Haruhisa and Nakajima, Katsuhisa and Nakajima, Setsuko
Journal of general virology, ISSN 0022-1317, 08/1993, Volume 74, Issue 8, pp. 1667 - 1672
Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Microbiology | Epidemiology | Virology | Biological Evolution | Influenza A Virus, H3N2 Subtype | Hong Kong | Base Sequence | Humans | Influenza A virus - genetics | Influenza A Virus, H2N2 Subtype | Molecular Sequence Data | Neuraminidase - genetics | Viral Nonstructural Proteins - genetics | Influenza A virus - enzymology | Index Medicus
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9. Full Text Nucleotide sequences of the neuraminidase genes of influenza A/Leningrad/134/57 (H2N2) virus and two of its live, attenuated, cold- adapted variants
by Klimov, A.I and Klimov, Alexander I and Romanova, J.R and Romanova, Julia R and Egorov, A.Y and Egorov, Andrei Y and Lukashok, Irina V and Lukashok, I.V and Kiseleva, I.V and Kiseleva, Irina V and Alexandrova, Galina I and Alexandrova, G.I and Cox, N.J and Cox, Nancy J
Virus genes, ISSN 0920-8569, 02/1995, Volume 10, Issue 1, pp. 95 - 98
nucleotide sequence | PCR restriction analysis | NA gene | influenza A virus | Genetic Variation | Amino Acid Sequence | Base Sequence | Humans | Influenza A virus - genetics | Influenza A Virus, H2N2 Subtype | Molecular Sequence Data | Neuraminidase - genetics | Reassortant Viruses - genetics | Influenza A virus - enzymology | DNA, Viral | Influenza | Analysis | Biological products | Index Medicus
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10. Full Text Crystallization and peptide maps of neuraminidase “heads” from H2N2 and H3N2 influenza virus strains
by Laver, W.G
Virology (New York, N.Y.), ISSN 0042-6822, 1978, Volume 86, Issue 1, pp. 78 - 87
Influenza A Virus, H3N2 Subtype | Species Specificity | Neuraminidase - analysis | Neuraminidase - isolation & purification | Recombination, Genetic | Crystallization | Influenza A Virus, H2N2 Subtype | Influenza A virus - enzymology | Peptides - analysis | Viral Proteins - analysis | Index Medicus
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11. The structure of oligosaccharide fragments of glycoproteins from influenza virus A/Krasnodar/101/59/(H2N2)--heavy and light chains of hemagglutinin and neuraminidase
by Arbatskiĭ, N P and Zheltova, A O and Iurtov, D V and Derevitskaia, V A and Kochetkov, N K
Bioorganicheskaia khimiia, ISSN 0132-3423, 12/1989, Volume 15, Issue 12, p. 1641
Neuraminidase - analysis | Oligosaccharides - analysis | Amino Acids - analysis | Influenza A Virus, H2N2 Subtype | Influenza A virus - immunology | Chromatography, High Pressure Liquid | Glycoproteins - analysis | Influenza A virus - enzymology | Influenza A virus - analysis | Hemagglutinins, Viral - analysis
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12. Full Text A topographic map of the enzyme active center and antigenic sites on the neuraminidase of influenza virus A/Tokyo/3/67 (H2N2)
by Jackson, David C and Webster, R.G
Virology (New York, N.Y.), ISSN 0042-6822, 1982, Volume 123, Issue 1, pp. 69 - 77
Influenza A Virus, H2N2 Subtype | Neuraminidase - antagonists & inhibitors | Protein Conformation | Antibodies, Monoclonal | Epitopes | Influenza A virus - enzymology | Binding Sites | Hemagglutinins, Viral - immunology | Neuraminidase - immunology | Index Medicus
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13. Full Text Neuraminidase gene from the early Asian strain of human influenza virus, A/RI/5-/57 (H2N2)
by Elleman, T C and Azad, A A and Ward, C W
Nucleic acids research, ISSN 0305-1048, 11/1982, Volume 10, Issue 21, pp. 7005 - 7015
Amino Acid Sequence | DNA Restriction Enzymes | Base Sequence | Influenza A virus - genetics | Cloning, Molecular | Genes, Viral | Influenza A Virus, H2N2 Subtype | Neuraminidase - genetics | Influenza A virus - enzymology | Index Medicus
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14. Mutations in the genes coding for hemagglutinin and neuraminidase in cold-adapted variants of the influenza virus A/Leningrad/134/57 (H2N2)
by Medvedeva, T E and Kudriavtseva, V K and Zhikhareva, I V and Romashkina, V V and Aleksandrova, G I and Klimov, A I
Voprosy virusologiĭ, ISSN 0507-4088, 03/1991, Volume 36, Issue 2, p. 96
Cold Temperature | Hemagglutinins, Viral - genetics | Influenza A virus - genetics | Influenza A Virus, H2N2 Subtype | Neuraminidase - genetics | Influenza A virus - enzymology | Mutation - genetics | Chick Embryo | Animals | Influenza Vaccines - genetics | Virus Replication | Adaptation, Physiological - genetics | Genes, Viral - genetics | Mice, Inbred CBA | Recombination, Genetic - genetics | Genetic Code - genetics | Influenza A virus - immunology | Genetic Variation - genetics | Mice | Vaccines, Attenuated - genetics
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15. Full Text Influenza A Virus Interaction with Murine Lymphocytes: I. The Influence of Influenza Virus A/Japan 305 (H2N2) on the Pattern of Migration of Recirculating Lymphocytes
by Woodruff, Judith J and Woodruff, Jack F
The Journal of immunology (1950), ISSN 0022-1767, 09/1976, Volume 117, Issue 3, pp. 852 - 858
Temperature | Lung - cytology | Rats, Inbred Strains | Orthomyxoviridae - immunology | Influenza A virus - radiation effects | Lymphocytes - immunology | Ultraviolet Rays | Time Factors | Surface Properties | alpha-Fetoproteins - pharmacology | Influenza A virus - immunology | Influenza A Virus, H2N2 Subtype | Neuraminidase - metabolism | Rats | Spleen - cytology | Influenza A virus - enzymology | Lymph Nodes - cytology | Cell Movement - drug effects | Animals | B-Lymphocytes - immunology | Virus Replication | Radiation Effects | T-Lymphocytes - immunology | Liver - cytology | Receptors, Drug
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16. Full Text The PB2 subunit of the influenza A virus RNA polymerase is imported into the mitochondrial matrix
by Long, Joshua C.D and Fodor, Ervin
Journal of virology, ISSN 0022-538X, 2016, Volume 90, Issue 19, pp. 8729 - 8738
Life Sciences & Biomedicine | Science & Technology | Virology | Viral Proteins - genetics | Microscopy, Electron | Protein Sorting Signals | Mice, Knockout | Protein Transport | Animals | Influenza A Virus, H1N1 Subtype - enzymology | Adaptor Proteins, Signal Transducing - deficiency | Fibroblasts | Mice | Adaptor Proteins, Signal Transducing - metabolism | Mitochondria - chemistry | Viral Proteins - analysis | Index Medicus
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17. Full Text Influenza A Virus Interaction with Murine Lymphocytes: II. Changes in Lymphocyte Surface Properties Induced by Influenza Virus A/Japan 305 (H2N2)
by Woodruff, Judith J and Woodruff, Jack F
The Journal of immunology (1950), ISSN 0022-1767, 09/1976, Volume 117, Issue 3, pp. 859 - 864
Temperature | Influenza A Virus, H2N2 Subtype | Sialic Acids - metabolism | Neuraminidase - metabolism | Rats | Influenza A virus - enzymology | Rats, Inbred Strains | Cell Adhesion | Blood | Orthomyxoviridae - immunology | Immunoglobulins - metabolism | Animals | Lymphocytes - immunology | Isoelectric Point | Surface Properties | Female | Influenza A virus - immunology |