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1. Full Text Vaccinate for the next H2N2 pandemic now
by Ledgerwood, Julie E and Wei, Chih-Jen and Nabel, Gary J
Nature (London), ISSN 0028-0836, 03/2011, Volume 471, Issue 7337, pp. 157 - 158
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Influenza A Virus, H1N1 Subtype - immunology | Influenza Vaccines - administration & dosage | Vaccination - utilization | Humans | Pandemics - prevention & control | Birds - virology | Influenza, Human - epidemiology | Influenza A Virus, H2N2 Subtype - immunology | Influenza, Human - transmission | Pandemics - veterinary | Zoonoses - transmission | Zoonoses - virology | Animals | Influenza Vaccines - immunology | Zoonoses - epidemiology | Influenza, Human - virology | Child | Influenza, Human - prevention & control | Licenses | Medical research | Pandemics | Swine flu | Index Medicus
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2. Full Text Human Monoclonal Antibodies to Pandemic 1957 H2N2 and Pandemic 1968 H3N2 Influenza Viruses
by Jens C. Krause and Tshidi Tsibane and Terrence M. Tumpey and Chelsey J. Huffman and Randy Albrecht and David L. Blum and Irene Ramos and Ana Fernandez-Sesma and Kathryn M. Edwards and Adolfo García-Sastre and Christopher F. Basler and James E. Crowe Jr
Journal of Virology, ISSN 0022-538X, 06/2012, Volume 86, Issue 11, pp. 6334 - 6340
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies | Miscellaneous | Microbiology | Orthomyxoviridae Infections - prevention & control | Humans | Middle Aged | Molecular Sequence Data | Antibodies, Monoclonal - therapeutic use | Influenza A Virus, H2N2 Subtype - immunology | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Mutation, Missense | Influenza A Virus, H3N2 Subtype - growth & development | Influenza A Virus, H2N2 Subtype - growth & development | RNA, Viral - genetics | Adult | Female | Influenza, Human - virology | Antibodies, Monoclonal - immunology | Disease Models, Animal | Antibodies, Viral - therapeutic use | Antibodies, Monoclonal - isolation & purification | Influenza A Virus, H3N2 Subtype - immunology | Chick Embryo | Sequence Analysis, DNA | Antibodies, Viral - isolation & purification | Animals | Orthomyxoviridae Infections - mortality | Survival Analysis | Antibodies, Viral - immunology | Mice | Mice, Inbred BALB C | Influenza, Human - immunology | Index Medicus | Pathogenesis and Immunity
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3. Full Text An open‐label phase I trial of a live attenuated H2N2 influenza virus vaccine in healthy adults
by Talaat, Kawsar R and Karron, Ruth A and Liang, Philana H and McMahon, Bridget A and Luke, Catherine J and Thumar, Bhagvanji and Chen, Grace L and Min, Ji‐Young and Lamirande, Elaine W and Jin, Hong and Coelingh, Kathy L and Kemble, George W and Subbarao, Kanta
Influenza and other respiratory viruses, ISSN 1750-2640, 01/2013, Volume 7, Issue 1, pp. 66 - 73
influenza | live attenuated influenza vaccines | influenza vaccine | neuraminidase inhibition | human | H2N2 | Human | Live attenuated influenza vaccines | Neuraminidase inhibition | Influenza vaccine | Influenza | Infectious Diseases | Life Sciences & Biomedicine | Science & Technology | Virology | Influenza A Virus, H2N2 Subtype - isolation & purification | Influenza Vaccines - administration & dosage | Humans | Vaccination | Influenza Vaccines - adverse effects | Male | Treatment Outcome | Influenza A Virus, H2N2 Subtype - immunology | Virus Shedding | Antibodies, Viral - blood | Young Adult | Vaccines, Attenuated - immunology | Influenza Vaccines - immunology | Virus Replication | Vaccines, Attenuated - administration & dosage | Influenza A Virus, H2N2 Subtype - genetics | Adult | Female | Influenza, Human - virology | Influenza A Virus, H2N2 Subtype - physiology | Vaccines, Attenuated - adverse effects | Influenza, Human - prevention & control | Influenza, Human - immunology | Influenza vaccines | Influenza viruses | Immunoglobulin G | Clinical trials | Product development | Adults | Immunoglobulin A | Enzyme-linked immunosorbent assay | Public health | Headache | Cell culture | Epidemics | Pandemics | Laboratories | Genes | Antibodies | Viruses | Leukocytes (mononuclear) | Vaccines | Antibody response | Hepatitis | Pain | Infectivity | Peripheral blood mononuclear cells | Population | Attenuation | Safety | Evaluation | Hemagglutination | Immunogenicity | Swine flu | Replication | Index Medicus | Original
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4. Full Text The PB2 Subunit of the Influenza Virus RNA Polymerase Affects Virulence by Interacting with the Mitochondrial Antiviral Signaling Protein and Inhibiting Expression of Beta Interferon
by Katy M. Graef and Frank T. Vreede and Yuk-Fai Lau and Amber W. McCall and Simon M. Carr and Kanta Subbarao and Ervin Fodor
Journal of Virology, ISSN 0022-538X, 09/2010, Volume 84, Issue 17, pp. 8433 - 8445
Life Sciences & Biomedicine | Science & Technology | Virology | Influenza A Virus, H5N1 Subtype - enzymology | Influenza A Virus, H2N2 Subtype - enzymology | Humans | Influenza A virus - genetics | RNA Replicase - metabolism | Virulence | Molecular Sequence Data | Influenza A Virus, H5N1 Subtype - genetics | Viral Proteins - metabolism | Influenza A virus - pathogenicity | Interferon-beta - genetics | Female | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Amino Acid Sequence | Influenza, Human - metabolism | RNA Replicase - genetics | Viral Proteins - chemistry | Down-Regulation | Mice, Inbred C57BL | Viral Proteins - genetics | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza A Virus, H2N2 Subtype - pathogenicity | Influenza A virus - enzymology | Host-Pathogen Interactions | Sequence Alignment | Animals | Interferon-beta - metabolism | Influenza A Virus, H1N1 Subtype - enzymology | RNA Replicase - chemistry | Influenza, Human - genetics | Adaptor Proteins, Signal Transducing - genetics | Influenza A Virus, H2N2 Subtype - genetics | Protein Binding | Influenza A Virus, H5N1 Subtype - pathogenicity | Mice | Adaptor Proteins, Signal Transducing - metabolism | Index Medicus | Cellular Response to Infection
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5. Full Text Monoclonal antibody against N2 neuraminidase of cold adapted A/Leningrad/134/17/57 (H2N2) enables efficient generation of live attenuated influenza vaccines
by Shcherbik, Svetlana and Carney, Paul and Pearce, Nicholas and Stevens, James and Dugan, Vivien G and Wentworth, David E and Bousse, Tatiana
Virology (New York, N.Y.), ISSN 0042-6822, 09/2018, Volume 522, pp. 65 - 72
Live vaccine | Classical reassortment | Monoclonal antibody | Influenza | Neuraminidase | Life Sciences & Biomedicine | Science & Technology | Virology | Influenza A Virus, H2N2 Subtype - isolation & purification | Cell Line | Cold Temperature | Vaccines, Attenuated - isolation & purification | Humans | Viral Proteins - immunology | Technology, Pharmaceutical - methods | Influenza A Virus, H2N2 Subtype - immunology | Antibodies, Monoclonal - isolation & purification | Reassortant Viruses - isolation & purification | Antibodies, Viral - isolation & purification | Influenza Vaccines - isolation & purification | Neuraminidase - immunology | Reassortant Viruses - growth & development | Reassortant Viruses - immunology | Vaccines, Attenuated - immunology | Animals | Influenza A Virus, H2N2 Subtype - growth & development | Influenza Vaccines - immunology | Antibodies, Viral - immunology | Antibodies, Monoclonal - immunology | Virus Cultivation - methods | Prevention | Influenza viruses | Influenza vaccines | Lectins | Monoclonal antibodies | Index Medicus
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6. Full Text Genetic bases of the temperature-sensitive phenotype of a master donor virus used in live attenuated influenza vaccines: A/Leningrad/134/17/57 (H2N2)
by Isakova-Sivak, Irina and Chen, Li-Mei and Matsuoka, Yumiko and Voeten, J. Theo M and Kiseleva, Irina and Heldens, Jacco G.M and den Bosch, Han van and Klimov, Alexander and Rudenko, Larisa and Cox, Nancy J and Donis, Ruben O
Virology (New York, N.Y.), ISSN 0042-6822, 2011, Volume 412, Issue 2, pp. 297 - 305
Infectious Disease | Live attenuated influenza vaccine | Influenza A virus | cold-adapted virus, viral polymerase | Temperature-sensitive mutant | Life Sciences & Biomedicine | Science & Technology | Virology | Temperature | RNA Replicase - genetics | Humans | RNA Replicase - metabolism | Viral Plaque Assay | Viral Proteins - genetics | Genotype | Mutation, Missense | Viral Proteins - metabolism | Russia | Phenotype | Influenza A Virus, H2N2 Subtype - growth & development | Influenza Vaccines - genetics | Plasmids | Influenza A Virus, H2N2 Subtype - genetics | Genetic Vectors | Vaccines, Attenuated - genetics | Influenza vaccines | Genetic research | Lectins | Genetic aspects | Influenza | Index Medicus
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7. Full Text Inhibitory effect and possible mechanism of action of patchouli alcohol against influenza a (H2N2) virus
by Wu, Huaxing and Li, Beili and Wang, Xue and Jin, Mingyuan and Wang, Guonian
Molecules (Basel, Switzerland), ISSN 1420-3049, 08/2011, Volume 16, Issue 8, pp. 6489 - 6501
Docking | Mice | MTT | Influenza virus | Patchouli alcohol | Neuraminidase | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Influenza A Virus, H2N2 Subtype - drug effects | Sesquiterpenes - therapeutic use | Thermodynamics | Influenza A Virus, H2N2 Subtype - growth & development | Neuraminidase - chemistry | Inhibitory Concentration 50 | Protein Interaction Domains and Motifs | Binding Sites | Orthomyxoviridae Infections - drug therapy | Oseltamivir - pharmacology | Cell Line | Cell Survival - drug effects | Virus Replication - drug effects | Antiviral Agents - pharmacology | Protein Structure, Secondary | Administration, Oral | Antiviral Agents - therapeutic use | Orthomyxoviridae Infections - pathology | Neuraminidase - metabolism | Survival Rate | Mice, Inbred Strains | Molecular Dynamics Simulation | Animals | Orthomyxoviridae Infections - mortality | Dogs | Protein Binding | Neuraminidase - antagonists & inhibitors | Sesquiterpenes - pharmacology | Orthomyxoviridae Infections - virology | Index Medicus | influenza virus | docking | patchouli alcohol | mice | neuraminidase
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8. Full Text Replication of live attenuated cold-adapted H2N2 influenza virus vaccine candidates in non human primates
by Broadbent, Andrew J and Santos, Celia P and Paskel, Myeisha and Matsuoka, Yumiko and Lu, Janine and Chen, Zhongying and Jin, Hong and Subbarao, Kanta
Vaccine, ISSN 0264-410X, 2014, Volume 33, Issue 1, pp. 193 - 200
Allergy and Immunology | LAIV | Vaccine | Influenza | Non-human primate | Monkey | H2N2 | Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Mutant Proteins - genetics | Adaptation, Biological | Cercopithecus aethiops | Macaca fascicularis | Male | Macaca mulatta | Viral Load | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Animals | Virus Replication | Influenza A Virus, H2N2 Subtype - genetics | Female | Influenza Vaccines | Influenza A Virus, H2N2 Subtype - physiology | Influenza viruses | Influenza vaccines | Primates | Proteins | Candidates | Pandemics | Swine flu | Genes | Bird migration | Clinical trials | Viruses | Genetics | Vaccines | Eggs | Index Medicus | influenza | vaccine | non-human primate | monkey
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9. Full Text Deletions in the Neuraminidase Stalk Region of H2N2 and H9N2 Avian Influenza Virus Subtypes Do Not Affect Postinfluenza Secondary Bacterial Pneumonia
by Ashok K. Chockalingam and Danielle Hickman and Lindomar Pena and Jianqiang Ye and Andrea Ferrero and Jose R. Echenique and Hongjun Chen and Troy Sutton and Daniel R. Perez
Journal of Virology, ISSN 0022-538X, 04/2012, Volume 86, Issue 7, pp. 3564 - 3573
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | Lung - microbiology | Influenza A Virus, H2N2 Subtype - enzymology | Humans | Influenza A Virus, H2N2 Subtype - chemistry | Neuraminidase - genetics | Influenza, Human - complications | Viral Proteins - metabolism | Influenza A Virus, H9N2 Subtype - chemistry | Lung - virology | Gene Deletion | Neuraminidase - chemistry | Female | Influenza, Human - virology | Influenza A Virus, H9N2 Subtype - enzymology | Streptococcus pneumoniae - physiology | Cell Line | Pneumonia, Bacterial - microbiology | Influenza A Virus, H9N2 Subtype - genetics | Viral Proteins - chemistry | Pneumonia, Bacterial - complications | Neuraminidase - metabolism | Viral Proteins - genetics | Coinfection - virology | Amino Acid Motifs | Bacterial Adhesion | Coinfection - microbiology | Animals | Chickens | Influenza A Virus, H2N2 Subtype - genetics | Influenza in Birds - virology | Mice | Mice, Inbred BALB C | Index Medicus | Pathogenesis and Immunity
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10. Full Text Safety, immunogencity, and efficacy of a cold-adapted A/Ann Arbor/6/60 (H2N2) vaccine in mice and ferrets
by Chen, Grace L and Lamirande, Elaine W and Jin, Hong and Kemble, George and Subbarao, Kanta
Virology (New York, N.Y.), ISSN 0042-6822, 2010, Volume 398, Issue 1, pp. 109 - 114
Infectious Disease | Live attenuated influenza vaccines | A/Ann Arbor/6/60 (H2N2) | Life Sciences & Biomedicine | Science & Technology | Virology | Adaptation, Physiological | Orthomyxoviridae Infections - prevention & control | Cold Temperature | Influenza Vaccines - adverse effects | Male | Influenza A Virus, H2N2 Subtype - immunology | Ferrets | Lung - virology | Animals | Influenza Vaccines - immunology | Virus Replication | Influenza A Virus, H2N2 Subtype - genetics | Vaccines, Attenuated | Female | Mice | Mice, Inbred BALB C | Mutation | Orthomyxoviridae Infections - virology | Index Medicus | ANIMALS | ANTIBODIES | INFECTIOUS DISEASES | PARASITES | RODENTS | SAFETY | INFLUENZA | AGGLUTININS | 60 APPLIED LIFE SCIENCES | MICROORGANISMS | INHIBITION | DISEASES | ATTENUATION | VERTEBRATES | HEMAGGLUTININS | MICE | VIRAL DISEASES | VIRUSES | VACCINES | MAMMALS | A | Ann Arbor | 6 | 60 (H2N2)
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