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1. Full Text Structure-Based Discovery of the Novel Antiviral Properties of Naproxen against the Nucleoprotein of Influenza A Virus
by Nathalie Lejal and Bogdan Tarus and Edwige Bouguyon and Sylvie Chenavas and Nicolas Bertho and Bernard Delmas and Rob W. H. Ruigrok and Carmelo Di Primo and Anny Slama-Schwok
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 05/2013, Volume 57, Issue 5, pp. 2231 - 2242
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Biological and medical sciences | Medical sciences | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Nucleoproteins - chemistry | Influenza A Virus, H3N2 Subtype - drug effects | Influenza A Virus, H3N2 Subtype - metabolism | Naproxen - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Viral Proteins - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | RNA, Viral - antagonists & inhibitors | Antiviral Agents - chemistry | Madin Darby Canine Kidney Cells | RNA, Viral - metabolism | Binding Sites | Influenza A Virus, H1N1 Subtype - metabolism | Orthomyxoviridae Infections - drug therapy | Antiviral Agents - pharmacology | Viral Proteins - chemistry | Viral Proteins - antagonists & inhibitors | Drug Repositioning | Influenza A Virus, H1N1 Subtype - drug effects | Drug Discovery | Molecular Dynamics Simulation | Nucleoproteins - antagonists & inhibitors | Naproxen - chemistry | Point Mutation | Animals | Influenza A Virus, H3N2 Subtype - chemistry | RNA, Viral - chemistry | Nucleoproteins - metabolism | Dogs | Protein Binding | Influenza A Virus, H1N1 Subtype - chemistry | Mice | Molecular Docking Simulation | Orthomyxoviridae Infections - virology | Index Medicus | Anti-Inflammatory Agents, Non-Steroidal | Influenza A Virus, H3N2 Subtype | Nucleoproteins | Biochemistry, Molecular Biology | Viral Proteins | Antiviral Agents | Life Sciences | Naproxen | RNA, Viral | Influenza A Virus, H1N1 Subtype | Biomolecules | Orthomyxoviridae Infections
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2. Full Text Distinct Effects of T-705 (Favipiravir) and ribavirin on influenza virus replication and Viral RNA Synthesis
by Vanderlinden, Evelien and Vrancken, Bram and Houdt, Jeroen Van and Rajwanshi, Vivek K and Gillemot, Sarah and Andrei, Graciela and Lemey, Philippe and Naesens, Lieve
Antimicrobial agents and chemotherapy, ISSN 0066-4804, 11/2016, Volume 60, Issue 11, pp. 6679 - 6691
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | DNA-Directed RNA Polymerases - antagonists & inhibitors | Influenza A Virus, H3N2 Subtype - drug effects | Humans | Influenza A Virus, H3N2 Subtype - metabolism | Reassortant Viruses - genetics | Reassortant Viruses - drug effects | Structure-Activity Relationship | Influenza A Virus, H3N2 Subtype - genetics | IMP Dehydrogenase - genetics | Influenza A Virus, H1N1 Subtype - growth & development | Viral Proteins - metabolism | Influenza A Virus, H3N2 Subtype - growth & development | RNA, Viral - antagonists & inhibitors | Antiviral Agents - chemistry | Madin Darby Canine Kidney Cells | Influenza A Virus, H1N1 Subtype - genetics | Influenza A Virus, H1N1 Subtype - metabolism | Amides - pharmacology | A549 Cells | Virus Replication - drug effects | Antiviral Agents - pharmacology | Reassortant Viruses - metabolism | RNA, Viral - biosynthesis | Viral Proteins - genetics | Viral Proteins - antagonists & inhibitors | DNA-Directed RNA Polymerases - genetics | Ribavirin - chemistry | Influenza A Virus, H1N1 Subtype - drug effects | Chick Embryo | Reassortant Viruses - growth & development | IMP Dehydrogenase - metabolism | Pyrazines - chemistry | Animals | Mutation - drug effects | Sequence Analysis, RNA | IMP Dehydrogenase - antagonists & inhibitors | Gene Expression Regulation, Viral | Dogs | Amides - chemistry | DNA-Directed RNA Polymerases - metabolism | Pyrazines - pharmacology | Ribavirin - pharmacology | Index Medicus
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3. Full Text NS1 protein mutation I64T affects interferon responses and virulence of circulating H3N2 human influenza A viruses
by DeDiego, Marta L and Nogales, Aitor and Lambert-Emo, Kris and Martinez-Sobrido, Luis and Topham, David J
Journal of virology, ISSN 0022-538X, 2016, Volume 90, Issue 21, pp. 9693 - 9711
Life Sciences & Biomedicine | Science & Technology | Virology | Virulence - drug effects | Influenza A Virus, H3N2 Subtype - drug effects | Humans | Immunity, Innate - genetics | Cercopithecus aethiops | Influenza A Virus, H3N2 Subtype - genetics | Leukocytes, Mononuclear - virology | HEK293 Cells | Immune Evasion - genetics | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Vero Cells | A549 Cells | Cell Line | Antiviral Agents - pharmacology | Interferons - pharmacology | Influenza A Virus, H3N2 Subtype - pathogenicity | Viral Nonstructural Proteins - genetics | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza A Virus, H1N1 Subtype - drug effects | Mutation - genetics | Animals | Immune Evasion - drug effects | RNA, Double-Stranded - genetics | Cell Line, Tumor | Cleavage And Polyadenylation Specificity Factor - genetics | Index Medicus
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4. Full Text Surveillance of Resistance to Adamantanes among Influenza A(H3N2) and A(H1N1) Viruses Isolated Worldwide
by Varough M. Deyde and Xiyan Xu and Rick A. Bright and Michael Shaw and Catherine B. Smith and Ye Zhang and Yuelong Shu and Larisa V. Gubareva and Nancy J. Cox and Alexander I. Klimov
The Journal of infectious diseases, ISSN 0022-1899, 7/2007, Volume 196, Issue 2, pp. 249 - 257
Influenza A virus | Antivirals | Phylogenetics | Viruses | Amino acids | Orthomyxoviridae | Evolution | Infections | Preventive medicine | Drug resistance | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Antiviral agents | Biological and medical sciences | Medical sciences | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Antiviral Agents - pharmacology | Global Health | Influenza A Virus, H3N2 Subtype - drug effects | Humans | Drug Resistance, Viral | Influenza A Virus, H3N2 Subtype - genetics | Phylogeny | Influenza A Virus, H1N1 Subtype - drug effects | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Microbial Sensitivity Tests | Amantadine - pharmacology | Influenza A Virus, H1N1 Subtype - genetics | Sentinel Surveillance | Rimantadine - pharmacology | Influenza viruses | Prevention | Amantadine | Analysis | Influenza | Patient outcomes | Development and progression | Research | Index Medicus | Abridged Index Medicus
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5. Full Text Impact of the Baloxavir-Resistant Polymerase Acid I38T Substitution on the Fitness of Contemporary Influenza A(H1N1)pdm09 and A(H3N2) Strains
by Checkmahomed, Liva and M’hamdi, Zeineb and Carbonneau, Julie and Venable, Marie-Christine and Baz, Mariana and Abed, Yacine and Boivin, Guy
The Journal of infectious diseases, ISSN 0022-1899, 01/2020, Volume 221, Issue 1, pp. 63 - 70
Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Thiepins - therapeutic use | Triazines - therapeutic use | Thiepins - pharmacology | Influenza A Virus, H3N2 Subtype - genetics | Viral Proteins - metabolism | Lung - virology | Madin Darby Canine Kidney Cells | Inhibitory Concentration 50 | Female | Influenza A Virus, H1N1 Subtype - genetics | Orthomyxoviridae Infections - drug therapy | Oxazines - pharmacology | Pyridines - therapeutic use | Virus Replication - drug effects | Antiviral Agents - pharmacology | Triazines - pharmacology | Influenza A Virus, H3N2 Subtype - enzymology | RNA-Dependent RNA Polymerase - genetics | Antiviral Agents - therapeutic use | Influenza A Virus, H3N2 Subtype - pathogenicity | Mice, Inbred C57BL | Pyridones | RNA-Dependent RNA Polymerase - metabolism | Viral Proteins - genetics | Influenza A Virus, H1N1 Subtype - pathogenicity | Morpholines | Drug Resistance, Viral - genetics | Phenotype | Animals | Influenza A Virus, H1N1 Subtype - enzymology | Oxazines - therapeutic use | Dogs | Dibenzothiepins | Mice | Pyridines - pharmacology | Mutation | Viral Load - drug effects | Orthomyxoviridae Infections - virology | Amino Acid Substitution | Polymerase chain reaction | Oseltamivir | Cell culture | Influenza | Virulence | Viruses | Influenza A | Experiments | Fitness | Mutants | Index Medicus | Abridged Index Medicus | influenza | Major and Brief Reports | A(H3N2) | I38T | A(H1N1)pdm09 | baloxavir | resistance
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6. Full Text Neuraminidase Inhibitor Resistance after Oseltamivir Treatment of Acute Influenza A and B in Children
by Iain Stephenson and Jane Democratis and Angie Lackenby and Teresa McNally and James Smith and Manish Pareek and Joanna Ellis and Alison Bermingham and Karl Nicholson and Maria Zambon
Clinical infectious diseases, ISSN 1058-4838, 2/2009, Volume 48, Issue 4, pp. 389 - 396
Cercopithecine herpesvirus 1 | Influenza A virus | Reverse transcriptase polymerase chain reaction | Articles and Commentaries | Antivirals | Viruses | Orthomyxoviridae | Children | Drug resistance | Inhibitory concentration 50 | H3N2 subtype influenza A virus | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Influenza A Virus, H3N2 Subtype - drug effects | Oseltamivir - therapeutic use | Humans | Influenza A virus - genetics | Drug Resistance, Viral | Child, Preschool | Neuraminidase - genetics | Infant | Male | Influenza A Virus, H3N2 Subtype - genetics | Viral Load | Microbial Sensitivity Tests | Influenza B virus - genetics | Influenza A Virus, H1N1 Subtype - isolation & purification | Influenza A Virus, H3N2 Subtype - isolation & purification | Female | Influenza, Human - virology | Influenza B virus - drug effects | Influenza, Human - drug therapy | Child | Influenza A Virus, H1N1 Subtype - genetics | Antiviral Agents - therapeutic use | Influenza B virus - isolation & purification | Viral Proteins - genetics | Influenza A virus - isolation & purification | Influenza A Virus, H1N1 Subtype - drug effects | Sequence Analysis, DNA | Influenza A virus - drug effects | Influenza | Patient outcomes | Reports | Drug therapy | Diseases | Virology | Children & youth | Index Medicus
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7. Full Text Human miR-3145 inhibits influenza A viruses replication by targeting and silencing viral PB1 gene
by Khongnomnan, Kritsada and Makkoch, Jarika and Poomipak, Witthaya and Poovorawan, Yong and Payungporn, Sunchai
Experimental biology and medicine (Maywood, N.J.), ISSN 1535-3702, 12/2015, Volume 240, Issue 12, pp. 1630 - 1639
viral replication | inhibition | miRNA | miR-3145 | silencing | influenza A virus | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Virus Replication - drug effects | Antiviral Agents - pharmacology | Gene Silencing - drug effects | Influenza A Virus, H3N2 Subtype - drug effects | Influenza A Virus, H5N1 Subtype - physiology | Virus Replication - genetics | Influenza A Virus, H1N1 Subtype - physiology | Influenzavirus A - physiology | Viral Proteins - genetics | Viral Proteins - antagonists & inhibitors | Influenza A Virus, H5N1 Subtype - drug effects | Influenza A Virus, H5N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - genetics | Influenza A Virus, H1N1 Subtype - drug effects | MicroRNAs - pharmacology | Influenzavirus A - drug effects | Genes, Viral - drug effects | Influenza A Virus, H3N2 Subtype - physiology | Influenza A Virus, H1N1 Subtype - genetics | Real-Time Polymerase Chain Reaction | Influenzavirus A - genetics | Index Medicus | Original Research
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8. Full Text New Small Molecule Entry Inhibitors Targeting Hemagglutinin-Mediated Influenza A Virus Fusion
by Arnab Basu and Aleksandar Antanasijevic and Minxiu Wang and Bing Li and Debra M. Mills and Jessica A. Ames and Peter J. Nash and John D. Williams and Norton P. Peet and Donald T. Moir and Mark N. Prichard and Kathy A. Keith and Dale L. Barnard and Michael Caffrey and Lijun Rong and Terry L. Bowlin
Journal of Virology, ISSN 0022-538X, 02/2014, Volume 88, Issue 3, pp. 1447 - 1460
Life Sciences & Biomedicine | Science & Technology | Virology | Small Molecule Libraries - pharmacology | Influenza A Virus, H3N2 Subtype - drug effects | Influenza A Virus, H5N1 Subtype - physiology | Humans | Influenza A virus - genetics | Influenza A Virus, H1N1 Subtype - physiology | Influenza A Virus, H5N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - genetics | Virus Internalization - drug effects | Antiviral Agents - chemistry | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Cell Line | Influenza A virus - physiology | Antiviral Agents - pharmacology | Hemagglutinins, Viral - metabolism | Hemagglutinins, Viral - genetics | Influenza A Virus, H5N1 Subtype - drug effects | Poultry Diseases - virology | Influenza A Virus, H1N1 Subtype - drug effects | Small Molecule Libraries - chemistry | Animals | Chickens | Influenza in Birds - virology | Influenza A Virus, H3N2 Subtype - physiology | Influenza A virus - drug effects | Index Medicus | Vaccines and Antiviral Agents
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9. Full Text Antiviral activity of chlorogenic acid against influenza A (H1N1/H3N2) virus and its inhibition of neuraminidase
by DIng, Yue and Cao, Zeyu and Cao, Liang and DIng, Gang and Wang, Zhenzhong and Xiao, Wei
Scientific reports, ISSN 2045-2322, 04/2017, Volume 7, Issue 1, pp. 45723 - 45723
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Lung - pathology | Influenza A Virus, H3N2 Subtype - drug effects | Humans | Influenza A Virus, H1N1 Subtype - drug effects | Antiviral Agents - administration & dosage | Lung - virology | Animals | Lung - drug effects | Dogs | Madin Darby Canine Kidney Cells | Female | Neuraminidase - antagonists & inhibitors | Mice, Inbred BALB C | Chlorogenic Acid - administration & dosage | Influenza, Human - prevention & control | Oseltamivir | Animal models | Intravenous administration | Influenza | Exo-a-sialidase | Antiviral activity | NP protein | Respiratory tract diseases | Chlorogenic acid | Immunofluorescence | Parainfluenza | Hepatitis B | Index Medicus
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10. Full Text Surveillance for Neuraminidase Inhibitor Resistance among Human Influenza A and B Viruses Circulating Worldwide from 2004 to 2008
by Tiffany G. Sheu and Varough M. Deyde and Margaret Okomo-Adhiambo and Rebecca J. Garten and Xiyan Xu and Rick A. Bright and Eboneé N. Butler and Teresa R. Wallis and Alexander I. Klimov and Larisa V. Gubareva
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 09/2008, Volume 52, Issue 9, pp. 3284 - 3292
Pharmacology & Pharmacy |