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1. Full Text Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets
by Sander Herfst and Eefje J. A. Schrauwen and Martin Linster and Salin Chutinimitkul and Emmie de Wit and Vincent J. Munster and Erin M. Sorrell and Theo M. Bestebroer and David F. Burke and Derek J. Smith and Guus F. Rimmelzwaan and Albert D. M. E. Osterhaus and Ron A. M. Fouchier
Science (American Association for the Advancement of Science), ISSN 0036-8075, 6/2012, Volume 336, Issue 6088, pp. 1534 - 1541
Receptors | Inoculation | Experimental infection | Disease transmission | Pandemics | REPORTS | Viruses | Orthomyxoviridae | Ferrets | Genetic mutation | Amino acid substitution | particle size | Influenza virus A H5N1 | antiviral resistance | hemagglutination test | virus replication | virus transmission | site directed mutagenesis | virus particle | Influenza virus A | animal experiment | nose smear | review | animal tissue | virus isolation | DNA modification | nonhuman | sequence analysis | amino acid substitution | priority journal | ferret | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Immune Sera | Reassortant Viruses - pathogenicity | Influenza A Virus, H5N1 Subtype - physiology | Poultry | Receptors, Virus - metabolism | Air Microbiology | Humans | Virulence | Molecular Sequence Data | Influenza A Virus, H5N1 Subtype - genetics | Virus Shedding | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Respiratory System - virology | Female | Influenza, Human - virology | Oseltamivir - pharmacology | Disease Models, Animal | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Reverse Genetics | Antiviral Agents - pharmacology | Mutagenesis, Site-Directed | RNA Replicase - genetics | Viral Proteins - chemistry | Sialic Acids - metabolism | Viral Proteins - genetics | Influenza, Human - epidemiology | Containment of Biohazards | Influenza A Virus, H5N1 Subtype - drug effects | Influenza in Birds - epidemiology | Influenza, Human - transmission | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Animals | Orthomyxoviridae Infections - transmission | Virus Replication | RNA Replicase - chemistry | Influenza in Birds - virology | Influenza A Virus, H5N1 Subtype - pathogenicity | Mutation | Serial Passage | Orthomyxoviridae Infections - virology | Amino Acid Substitution | Avian influenza | Diseases and pests | Physiological aspects | Development and progression | Research | Animal diseases | Amino acids | Avian flu | Small mammals | Index Medicus | Polymerase | Human | Proteins | Influenza | Droplets | Genetic modification
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2. Full Text Avian flu Isolation of drug-resistant H5N1 virus
by Someya, Kazuhiko and Goto, Hideo and Pham, N. Dinh and Horimoto, Taisuke and Muramoto, Yukiko and Le, Q. Mai and Nguyen, Khan H. L and Kiso, Maki and Nguyen, T. Hien and Suzuki, Yasuo and Takada, Ayato and Ngyen, Ha H and Yamada, Shinya and Kawaoka, Yoshihiro and Sakai, Yuko T and Suzuki, Takashi
Nature, ISSN 0028-0836, 10/2005, Volume 437, Issue 7062, pp. 1108 - 1108
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Influenza A virus - genetics | Neuraminidase - genetics | Acetamides - pharmacology | Influenza A Virus, H5N1 Subtype | Sialic Acids | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Zanamivir | Acetamides - therapeutic use | DNA Mutational Analysis | Neuraminidase - chemistry | Polymerase Chain Reaction | Inhibitory Concentration 50 | Adult | Female | Influenza, Human - virology | Influenza, Human - drug therapy | Influenza A virus - growth & development | Neuraminidase - metabolism | Guanidines | Influenza A virus - isolation & purification | Influenza, Human - transmission | Ferrets | Mutation - genetics | Oseltamivir | Drug Resistance, Viral - genetics | Acetamides - supply & distribution | Adolescent | Neuraminidase - antagonists & inhibitors | Influenza A virus - drug effects | Influenza, Human - prevention & control | Acetamides - administration & dosage | Pyrans | Index Medicus
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3. Full Text Antiviral resistance among highly pathogenic influenza A (H5N1) viruses isolated worldwide in 2002–2012 shows need for continued monitoring
by Govorkova, Elena A and Baranovich, Tatiana and Seiler, Patrick and Armstrong, Jianling and Burnham, Andrew and Guan, Yi and Peiris, Malik and Webby, Richard J and Webster, Robert G
Antiviral research, ISSN 0166-3542, 05/2013, Volume 98, Issue 2, pp. 297 - 304
Resistance | Oseltamivir | Amantadine | H5N1 influenza virus | Neuraminidase inhibitors | Zanamivir | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Virology | Antiviral agents | Biological and medical sciences | Medical sciences | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Antiviral Agents - pharmacology | Humans | Drug Resistance, Viral | Viral Proteins - genetics | Birds | Influenza A Virus, H5N1 Subtype - classification | Influenza A Virus, H5N1 Subtype - drug effects | Influenza A Virus, H5N1 Subtype - genetics | Phylogeny | Influenza A Virus, H5N1 Subtype - isolation & purification | Animals | Influenza in Birds - virology | Influenza A Virus, H5N1 Subtype - pathogenicity | Influenza, Human - virology | Virus diseases | Avian influenza | Avian influenza viruses | Index Medicus | zanamivir | neuraminidase inhibitors | oseltamivir | resistance
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4. Full Text Evolution of H5N1 avian influenza viruses in Asia
by Aubin, Jean-Thierry and Azebi, Saliha and Balish, Amanda and Banks, Jill and Bhat, Niranjan and Bright, Rick A and Brown, Ian and Buchy, Philippe and Burguiere, Ana-Maria and Chen, Hua-Ian and Cheng, Peter and Cox, Nancy J and Crosier, Alice and Curns, Aaron and Cuvelier, Frédèrique and Deng, Guohua and Desheva, Julia and Desvaux, Stéphanie and Diep, Nguyen Hong and Donis, Ruben O and Douglas, Alan and Dowell, Scott F and Dung, Nguyen Tien and Edwards, Lindsay and Fukuda, Keiji and Garten, Rebecca and Govorkova, Elena and Gregory, Victoria and Hampson, Alan and Hanh, Nguyen Thi Hong and Harper, Scott and Hay, Alan and Hoffmann, Erich and Hulse, Diane and Imai, Masaki and Itamura, Shigeyuki and Jadhao, Samadhan and Jeannin, Patricia and Kang, Chun and Katz, Jackie and Kim, Jae-Hong and Klimov, Alexander and Kwon, Yong-Kuk and Lee, Chang-Won and Lien, Phuong Song and Li, Yanbing and Lim, Wilina and Lin, Yi Pu and Lindstom, Stephen and Loftin, LaMorris and Mabry, Jan and Mai, Le Quynh and Maines, Taronna and Manuguerra, Jean-Claude and Mase, Masaji and Matsuoka, Yumi and McCarron, Margaret and Medina, Marie-Jo and Nguyen, Doan and Ninomiya, Ai and Obuchi, Masatsugu and Odagiri, Takato and Peiris, Malik and Perdue, Michael L and Reynes, Jean-Marc and Robertson, James and Rousseaux, Claudine and Saito, Takehiko and Sangkitporn, Somchai and Shaw, Michael and Simmerman, James M and Slomka, M and Smith, Catherine and Sorn, San and Spackman, Erica and Stöhr, Klaus and Suarez, David L and Sung, Haan Woo and Swayne, David E and Tardy-Panit, Maryse and Tashiro, Masato and Thawatsupha, Pranee and Tumpey, Terrence and Uyeki, Timothy and Van Tu, Phan and Van Der Werf, Sylvie and Vong, Sirenda and Webby, Richard and Webster, Robert and Wood, John and Xu, Xiyan and Yi, Guan and Zhang, Wenging and World Hlth Org Global Influenza Pr and World Health Organization Global Influenza Program Surveillance Network and The World Health Organization Global Influenza Program Surveillance Network
Emerging infectious diseases, ISSN 1080-6040, 10/2005, Volume 11, Issue 10, pp. 1515 - 1521
Infectious Diseases | Immunology | Life Sciences & Biomedicine | Science & Technology | Antiviral Agents - therapeutic use | Poultry | Humans | Influenza, Human - epidemiology | Influenza A Virus, H5N1 Subtype - classification | Influenza A Virus, H5N1 Subtype - drug effects | Influenza A Virus, H5N1 Subtype - genetics | Influenza in Birds - epidemiology | Phylogeny | Poultry Diseases - virology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Genetic Variation | Asia - epidemiology | Phenotype | Animals | Chickens | Influenza in Birds - virology | Influenza, Human - virology | Neuraminidase - antagonists & inhibitors | Influenza Vaccines | Influenza, Human - drug therapy | Poultry Diseases - epidemiology | Evolution, Molecular | Avian influenza | Causes of | Health aspects | Index Medicus | Influenza in Birds | Influenza A Virus, H5N1 Subtype | Emerging diseases | Life Sciences | Animal biology | Antiviral Agents | Hemagglutinin Glycoproteins, Influenza Virus | Virology | Human health and pathology | Microbiology and Parasitology | Infectious diseases | Veterinary medicine and animal Health | Asia | Influenza, Human | Neuraminidase | Poultry Diseases | Adamantane | hemagglutinin | M2 protein | Avian | Research | NA protein | Influenza A Virus | Oseltamivir | molecular Evolution | virology | Influenza
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5. Full Text Determinants of Antiviral Effectiveness in Influenza Virus A Subtype H5N1
by Paul K. S. Chan and Nelson Lee and Mukhtiar Zaman and Wiku Adisasmito and Richard Coker and Wanna Hanshaoworakul and Viktor Gasimov and Ahmet Faik Oner and Nazim Dogan and Owen Tsang and Bounlay Phommasack and Sok Touch and Ebun Bamgboye and Anna Swenson and Stephen Toovey and Nancy A. Dreyer
The Journal of infectious diseases, ISSN 0022-1899, 11/2012, Volume 206, Issue 9, pp. 1359 - 1366
Respiratory insufficiency | Corticosteroids | Influenza A virus | Antivirals | Patient care | Viruses | Orthomyxoviridae | Infections | H5N1 subtype influenza A virus | Symptoms | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Infectious diseases | Medical sciences | Humans | Middle Aged | Child, Preschool | Respiratory Insufficiency - virology | Infant | Male | Influenza, Human - complications | Secondary Prevention | Young Adult | Influenza, Human - mortality | Adult | Female | Influenza, Human - virology | Influenza, Human - drug therapy | Child | Oseltamivir - pharmacology | Antiviral Agents - pharmacology | Respiratory Insufficiency - mortality | Treatment Outcome | Influenza A Virus, H5N1 Subtype - drug effects | Antiviral Agents - administration & dosage | Oseltamivir - administration & dosage | Adolescent | Survival Analysis | Aged | Oseltamivir phosphate | Usage | Prognosis | Research | Drug therapy | Influenza | Index Medicus | Abridged Index Medicus
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6. Full Text Cross protection by inactivated recombinant influenza viruses containing chimeric hemagglutinin conjugates with a conserved neuraminidase or M2 ectodomain epitope
by Kim, Ki-Hye and Jung, Yu-Jin and Lee, Youri and Park, Bo Ryoung and Oh, Judy and Lee, Yu-Na and Kim, Min-Chul and Jeeva, Subbiah and Kang, Sang-Moo
Virology (New York, N.Y.), ISSN 0042-6822, 11/2020, Volume 550, pp. 51 - 60
Heterosubtypic immunity | M2 extracellular domain epitope | Neuraminidase epitope | Cross protection | Recombinant chimeric influenza virus | Life Sciences & Biomedicine | Science & Technology | Virology | Influenza A Virus, H1N1 Subtype - immunology | Orthomyxoviridae Infections - prevention & control | Recombinant Fusion Proteins - immunology | Influenza Vaccines - administration & dosage | Viral Matrix Proteins - genetics | Influenza A Virus, H3N2 Subtype - drug effects | Humans | Vaccines, Inactivated | Cross Protection | Neuraminidase - genetics | Reassortant Viruses - genetics | Reassortant Viruses - drug effects | Influenza A Virus, H5N1 Subtype - genetics | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Influenza A Virus, H3N2 Subtype - genetics | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Influenza A Virus, H9N2 Subtype - immunology | Neuraminidase - immunology | Epitopes - immunology | Reassortant Viruses - immunology | Immunity, Cellular - drug effects | Vaccination - methods | Female | Influenza A Virus, H1N1 Subtype - genetics | Antibodies, Viral - biosynthesis | Influenza A Virus, H9N2 Subtype - genetics | Influenza A Virus, H9N2 Subtype - drug effects | Influenza A Virus, H5N1 Subtype - drug effects | Influenza A Virus, H1N1 Subtype - drug effects | Influenza A Virus, H3N2 Subtype - immunology | Animals | Influenza Vaccines - genetics | Influenza A Virus, H5N1 Subtype - immunology | Influenza Vaccines - biosynthesis | Immunity, Humoral - drug effects | Recombinant Fusion Proteins - genetics | Epitopes - chemistry | Mice | Mice, Inbred BALB C | Viral Matrix Proteins - immunology | Orthomyxoviridae Infections - virology | Orthomyxoviridae Infections - immunology | Index Medicus
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7. Full Text Study on the Antiviral Activities and Hemagglutinin-Based Molecular Mechanism of Novel Chlorogenin 3-O-beta-Chacotrioside Derivatives against H5N1 Subtype Viruses
by Shi, Wan-Zhen and Jiang, Ling-Zhi and Song, Gao-Peng and Wang, Sheng and Xiong, Ping and Ke, Chang-Wen
Viruses, ISSN 1999-4915, 03/2020, Volume 12, Issue 3, p. 304
Life Sciences & Biomedicine | Science & Technology | Virology | Cell Line | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Antiviral Agents - pharmacology | Cell Survival | Humans | Molecular Conformation | Models, Molecular | Neutralization Tests | Influenza A Virus, H5N1 Subtype - drug effects | Structure-Activity Relationship | Enzyme Activation - drug effects | Chick Embryo | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Virus Internalization | Dose-Response Relationship, Drug | Hemagglutination Inhibition Tests | Animals | Antiviral Agents - chemistry | Protein Binding | Molecular Structure | Influenza A Virus, H5N1 Subtype - metabolism | Binding Sites | Index Medicus | h5n1 subtype avian influenza virus | chlorogenin 3-o-β-chacotrioside derivatives | antiviral mechanism | hemagglutinin
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8. Full Text The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design
by Skehel, John J and Stevens, David J and Blackburn, G. Michael and Hay, Alan J and Gamblin, Steven J and Russell, Rupert J and Haire, Lesley F and Collins, Patrick J and Lin, Yi Pu
Nature, ISSN 0028-0836, 09/2006, Volume 443, Issue 7107, pp. 45 - 49
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains | Antiviral agents | Microbiology | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Virology | Antibiotics. Antiinfectious agents. Antiparasitic agents | Influenza A Virus, H5N1 Subtype - enzymology | Humans | Neuraminidase - genetics | Acetamides - pharmacology | Influenza A Virus, H5N1 Subtype - classification | Influenza A Virus, H5N1 Subtype - genetics | Antiviral Agents - metabolism | Antiviral Agents - chemistry | Drug Design | Neuraminidase - chemistry | Influenza in Birds - drug therapy | Binding Sites | Neuraminidase - classification | Antiviral Agents - pharmacology | Birds - virology | Models, Molecular | Influenza A Virus, H5N1 Subtype - drug effects | Mutation - genetics | Acetamides - metabolism | Oseltamivir | Drug Resistance, Viral - genetics | Animals | Influenza in Birds - virology | Neuraminidase - antagonists & inhibitors | Protein Conformation | Enzymes | Disease transmission | Pandemics | Inhibitor drugs | Avian flu | Crystal structure | Index Medicus
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9. Full Text Innate immune responses to influenza A H5N1: friend or foe?
by Peiris, Joseph Sriyal Malik and Cheung, Chung Yan and Leung, Connie Yin Hung and Nicholls, John Malcolm
Trends in immunology, ISSN 1471-4906, 2009, Volume 30, Issue 12, pp. 574 - 584
Allergy and Immunology | Life Sciences & Biomedicine | Immunology | Science & Technology | Influenza A Virus, H1N1 Subtype - immunology | Tumor Necrosis Factor-alpha - metabolism | Influenza, Human - pathology | Orthomyxoviridae Infections - physiopathology | Humans | Influenza A Virus, H3N2 Subtype - pathogenicity | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza, Human - epidemiology | Immunity, Innate | Influenza A Virus, H3N2 Subtype - immunology | Respiratory Distress Syndrome, Adult - immunology | Animals | Influenza A Virus, H5N1 Subtype - immunology | Interferons - metabolism | Influenza A Virus, H5N1 Subtype - pathogenicity | Mice | Influenza, Human - physiopathology | Orthomyxoviridae Infections - immunology | Influenza, Human - immunology | Avian influenza | Influenza viruses | Immune response | Health aspects | Analysis | Infections | Pandemics | Mutation | Respiratory distress syndrome | Genes | Index Medicus | Influenza A Virus, H3N2 Subtype | Respiratory Distress Syndrome, Adult | Interferons | Influenza A Virus, H5N1 Subtype | Tumor Necrosis Factor-alpha | Virology | Life Sciences | Microbiology and Parasitology | Influenza, Human | Influenza A Virus, H1N1 Subtype | Orthomyxoviridae Infections | influenza | cytokine | H5N1 | macrophage | pandemic | innate immune response
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