Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2611) 2611
Publication (439) 439
Newsletter (88) 88
Book Chapter (52) 52
Book Review (14) 14
Book / eBook (9) 9
Conference Proceeding (8) 8
Newspaper Article (6) 6
Reference (2) 2
Magazine Article (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (1370) 1370
humans (1306) 1306
index medicus (1099) 1099
influenza a virus - enzymology (872) 872
influenza (777) 777
virology (685) 685
viruses (565) 565
neuraminidase - antagonists & inhibitors (532) 532
neuraminidase - metabolism (520) 520
mice (490) 490
cell line (460) 460
biochemistry & molecular biology (458) 458
antiviral agents - pharmacology (428) 428
neuraminidase - genetics (409) 409
molecular sequence data (341) 341
influenza, human - virology (334) 334
neuraminidase (334) 334
viral proteins - metabolism (317) 317
influenza a virus - genetics (313) 313
neuraminidase - chemistry (311) 311
enzyme inhibitors - pharmacology (305) 305
influenza viruses (301) 301
viral proteins - genetics (293) 293
amino acid sequence (291) 291
influenza a virus, h1n1 subtype - enzymology (289) 289
orthomyxoviridae - enzymology (283) 283
models, molecular (276) 276
microbiology (274) 274
mutation (274) 274
virus diseases (273) 273
research (270) 270
proteins (267) 267
female (260) 260
research article (260) 260
dogs (255) 255
replication (252) 252
a virus (242) 242
health aspects (240) 240
influenza a virus - immunology (229) 229
virus replication (225) 225
infectious diseases (214) 214
hemagglutinin (211) 211
immunology (204) 204
antiviral agents - chemistry (202) 202
binding sites (202) 202
enzymes (202) 202
analysis (200) 200
oseltamivir (199) 199
infection (196) 196
influenza virus (196) 196
influenza a virus - drug effects (193) 193
multidisciplinary sciences (192) 192
base sequence (190) 190
protein binding (185) 185
influenza, human - drug therapy (184) 184
male (182) 182
kinetics (181) 181
zanamivir (179) 179
pharmacology & pharmacy (178) 178
influenza a virus - physiology (177) 177
drug design (176) 176
viral proteins - chemistry (172) 172
influenza a virus (171) 171
enzyme inhibitors - chemistry (170) 170
neuraminidase - immunology (170) 170
avian influenza (167) 167
chemistry, medicinal (165) 165
infections (164) 164
antiviral agents (163) 163
inhibitors (163) 163
influenza a virus, h5n1 subtype - enzymology (162) 162
medicine (161) 161
structure-activity relationship (161) 161
chick embryo (158) 158
rna replicase - metabolism (157) 157
influenza-virus (155) 155
oseltamivir - pharmacology (154) 154
mice, inbred balb c (153) 153
influenza b virus - enzymology (148) 148
protein conformation (147) 147
biology (144) 144
influenza a virus, h1n1 subtype - drug effects (142) 142
pandemics (142) 142
in-vitro (139) 139
influenza a virus, h1n1 subtype - genetics (138) 138
cell biology (136) 136
substrate specificity (134) 134
binding (133) 133
genetic aspects (133) 133
protein (131) 131
science (131) 131
article (130) 130
crystallography, x-ray (127) 127
viral proteins - antagonists & inhibitors (127) 127
virulence (125) 125
dna-directed rna polymerases - metabolism (124) 124
cells, cultured (123) 123
rna (122) 122
physiological aspects (120) 120
influenza, human - enzymology (117) 117
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2534) 2534
Russian (109) 109
Chinese (29) 29
Japanese (20) 20
German (17) 17
French (10) 10
Polish (6) 6
Spanish (4) 4
Czech (2) 2
Italian (2) 2
Bulgarian (1) 1
Portuguese (1) 1
Romanian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Influenza virus RNA polymerase: Insights into the mechanisms of viral RNA synthesis
by Te Velthuis, Aartjan J.W and Fodor, Ervin
Nature Reviews Microbiology, ISSN 1740-1526, 08/2016, Volume 14, Issue 8, pp. 479 - 493
The genomes of influenza viruses consist of multiple segments of single-stranded negative-sense RNA. Each of these segments is bound by the heterotrimeric... 
A VIRUS | MESSENGER-RNA | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | MICROBIOLOGY | NEGATIVE-STRAND RNA | INFECTED-CELLS | NS1 PROTEIN INTERACTS | ANTIVIRAL DRUG DEVELOPMENT | VIRION RNA | SMALL-MOLECULE INHIBITOR | Genome, Viral | Influenza A virus - physiology | Influenza B virus - enzymology | Humans | Influenza A virus - genetics | RNA Replicase - metabolism | RNA, Viral - biosynthesis | Models, Molecular | Viral Proteins - genetics | Influenza A virus - enzymology | Influenza B virus - physiology | Virion - metabolism | Viral Proteins - metabolism | Host-Pathogen Interactions | RNA Replicase - chemistry | Orthomyxoviridae - genetics | Protein Conformation | Ribonucleoproteins - genetics | Ribonucleoproteins - chemistry | Virus Replication - physiology | Orthomyxoviridae - physiology | Orthomyxoviridae - enzymology | Influenza viruses | Synthesis | Molecular structure | RNA | Genetic aspects | Virulence (Microbiology) | Properties | Identification and classification | Health aspects | RNA polymerases
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Structural insight into cap-snatching and RNA synthesis by influenza polymerase
by Reich, Stefan and Reich, Stefan and Guilligay, Delphine and Pflug, Alexander and Malet, Helene and Berger, Imre and Crepin, Thibaut and Hart, Darren and Lunardi, Thomas and Nanao, Max and Ruigrok, Rob W. H and Cusack, Stephen
Nature, ISSN 0028-0836, 12/2014, Volume 516, Issue 7531, pp. 361 - 366
Influenza virus polymerase uses a capped primer, derived by 'cap-snatching' from host pre-messenger RNA, to transcribe its RNA genome into mRNA and a... 
MESSENGER-RNAS | IN-VITRO | MAXIMUM-LIKELIHOOD | ENDONUCLEASE | REPLICATION | ACTIVE-SITE | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | P-PROTEINS | VIRUS VIRION RNA | SUBUNIT | Protein Structure, Tertiary | Influenza A virus - chemistry | Influenza B virus - enzymology | Promoter Regions, Genetic | Catalytic Domain | RNA, Viral - biosynthesis | Crystallization | Models, Molecular | Influenza A virus - enzymology | RNA Caps - metabolism | RNA, Viral - chemistry | Virus Replication | Gene Expression Regulation, Viral | Protein Binding | RNA Caps - chemistry | Influenza B virus - chemistry | DNA-Directed RNA Polymerases - chemistry | DNA-Directed RNA Polymerases - metabolism | Influenza viruses | Synthesis | RNA | Analysis | Crystals | Research | Structure | Health aspects | RNA polymerases | Ribonucleic acid--RNA | Influenza | Binding sites | Crystal structure | Biochemistry, Molecular Biology | RNA Caps | Influenza B virus | Life Sciences | DNA-Directed RNA Polymerases | Influenza A virus | RNA, Viral | Biomolecules
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Species difference in ANP32A underlies influenza A virus polymerase host restriction
by Long, Jason S and Giotis, Efstathios S and Moncorgé, Olivier and Frise, Rebecca and Mistry, Bhakti and James, Joe and Morisson, Mireille and Iqbal, Munir and Vignal, Alain and Skinner, Michael A and Barclay, Wendy S
Nature, ISSN 0028-0836, 01/2016, Volume 529, Issue 7584, pp. 101 - 104
Influenza pandemics occur unpredictably when zoonotic influenza viruses with novel antigenicity acquire the ability to transmit amongst humans(1). Host range... 
PB2 | REPLICATION | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | REVERSE GENETICS SYSTEM | ADAPTATION | RIBONUCLEOPROTEINS | GENERATION | RNA-POLYMERASE | SUBUNIT | RANGE | Influenza A Virus, H5N1 Subtype - enzymology | Influenza A Virus, H7N9 Subtype - physiology | Cricetulus | Species Specificity | Influenza A Virus, H5N1 Subtype - physiology | Humans | Influenza A virus - genetics | RNA Replicase - metabolism | Chickens - virology | Influenza A Virus, H5N1 Subtype - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Viral Proteins - metabolism | Avian Proteins - chemistry | Gene Knockdown Techniques | Intracellular Signaling Peptides and Proteins - deficiency | Transcription, Genetic | Influenza A Virus, H7N9 Subtype - enzymology | Amino Acid Sequence | Cell Line | Influenza A virus - physiology | Avian Proteins - metabolism | Cricetinae | RNA Replicase - genetics | Viral Proteins - genetics | Host Specificity | Influenza A virus - enzymology | Animals | Virus Replication | Avian Proteins - deficiency | Gene Expression Regulation, Viral | Intracellular Signaling Peptides and Proteins - chemistry | Dogs | Influenza A Virus, H7N9 Subtype - genetics | Evolution, Molecular | Avian influenza | Antiviral agents | Complications and side effects | Care and treatment | Research | Health aspects | Proteins | Pandemics | Genes | Viruses | Principal components analysis | Genomes | Mutation | RNA polymerase | Mammals | Avian flu
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Influenza hemagglutinin and neuraminidase membrane glycoproteins
by Gamblin, Steven J and Skehel, John J
Journal of Biological Chemistry, ISSN 0021-9258, 09/2010, Volume 285, Issue 37, pp. 28403 - 28409
Considerable progress has been made toward understanding the structural basis of the interaction of the two major surface glycoproteins of influenza A virus... 
B VIRUSES | RECEPTOR-BINDING PROPERTIES | HUMAN AIRWAY EPITHELIUM | X-RAY CRYSTALLOGRAPHY | CELL-SURFACE RECEPTOR | A H1N1 VIRUSES | CLEAVAGE SITE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DESIGN | SIALIC-ACID | STALK-LENGTH | Protein Structure, Tertiary | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Antiviral Agents - pharmacology | Antiviral Agents - therapeutic use | Humans | Influenza, Human - enzymology | Neuraminidase - metabolism | Structure-Activity Relationship | Influenza A virus - enzymology | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | N-Acetylneuraminic Acid - metabolism | Virus Attachment - drug effects | Drug Resistance, Viral - physiology | Animals | Neuraminidase - chemistry | Drug Resistance, Viral - drug effects | Neuraminidase - antagonists & inhibitors | Influenza, Human - drug therapy | Virus Structure | Virus | Virus Entry | Viral Protein | Minireviews | Glycobiology and Extracellular Matrices | Viral Immunology | Virus Assembly
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text The PB2 Subunit of the Influenza Virus RNA Polymerase Affects Virulence by Interacting with the Mitochondrial Antiviral Signaling Protein and Inhibiting Expression of Beta Interferon
by Katy M. Graef and Frank T. Vreede and Yuk-Fai Lau and Amber W. McCall and Simon M. Carr and Kanta Subbarao and Ervin Fodor
Journal of Virology, ISSN 0022-538X, 09/2010, Volume 84, Issue 17, pp. 8433 - 8445
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
SINGLE AMINO-ACID | A VIRUS | PA SUBUNIT | H5N1 | REPLICATION | VIROLOGY | HUMAN-CELLS | HOST-RANGE | HEPATITIS-C-VIRUS | MICE | ADAPTER PROTEIN | Influenza A Virus, H5N1 Subtype - enzymology | Influenza A Virus, H2N2 Subtype - enzymology | Humans | Influenza A virus - genetics | RNA Replicase - metabolism | Virulence | Molecular Sequence Data | Influenza A Virus, H5N1 Subtype - genetics | Viral Proteins - metabolism | Influenza A virus - pathogenicity | Interferon-beta - genetics | Female | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Amino Acid Sequence | Influenza, Human - metabolism | RNA Replicase - genetics | Viral Proteins - chemistry | Down-Regulation | Mice, Inbred C57BL | Viral Proteins - genetics | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza A Virus, H2N2 Subtype - pathogenicity | Influenza A virus - enzymology | Host-Pathogen Interactions | Sequence Alignment | Animals | Interferon-beta - metabolism | Influenza A Virus, H1N1 Subtype - enzymology | RNA Replicase - chemistry | Influenza, Human - genetics | Adaptor Proteins, Signal Transducing - genetics | Influenza A Virus, H2N2 Subtype - genetics | Protein Binding | Influenza A Virus, H5N1 Subtype - pathogenicity | Mice | Adaptor Proteins, Signal Transducing - metabolism | Cellular Response to Infection
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Structure of influenza A polymerase bound to the viral RNA promoter
by Pflug, Alexander and Pflug, Alexander and Guilligay, Delphine and Reich, Stefan and Cusack, Stephen
Nature, ISSN 0028-0836, 12/2014, Volume 516, Issue 7531, pp. 355 - 360
The influenza virus polymerase transcribes or replicates the segmented RNA genome (viral RNA) into viral messenger RNA or full-length copies. To initiate RNA... 
CAPPED RNAS | HEPATITIS-C VIRUS | MESSENGER-RNA | TERMINAL DOMAIN | VIRUS PB1 PROTEIN | ACTIVE-SITE | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | MUTATIONAL ANALYSIS | VIRION RNA | ENDONUCLEASE ACTIVITY | Protein Structure, Tertiary | Promoter Regions, Genetic | RNA, Viral - chemistry | Crystallization | Models, Molecular | Protein Binding | DNA-Directed RNA Polymerases - chemistry | Protein Subunits - chemistry | Influenza A virus - enzymology | Binding Sites | Influenza viruses | Physiological aspects | Influenza | RNA polymerases | Genomes | Ribonucleic acid--RNA | Binding sites | Crystal structure
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text A Mutant Influenza Virus That Uses an N1 Neuraminidase as the Receptor-Binding Protein
by Kathryn A. Hooper and Jesse D. Bloom
Journal of Virology, ISSN 0022-538X, 12/2013, Volume 87, Issue 23, pp. 12531 - 12540
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
A VIRUS | MEMBRANE-FUSION | CELLS | ATTACHMENT | ACID | EPITOPE | VIROLOGY | HEMAGGLUTININ | INFECTION | GENERATION | PEPTIDE | Influenza A Virus, H5N1 Subtype - enzymology | Receptors, Virus - metabolism | Humans | Influenza A virus - genetics | Molecular Sequence Data | Neuraminidase - genetics | Influenza A Virus, H5N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - genetics | Mutation, Missense | Phylogeny | Viral Proteins - metabolism | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Cell Line | Influenza, Human - metabolism | Influenza A Virus, H3N2 Subtype - enzymology | Neuraminidase - metabolism | Viral Proteins - genetics | Influenza A virus - enzymology | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Animals | Influenza A Virus, H1N1 Subtype - enzymology | Protein Binding | Mice | Influenza A virus - classification | Virus-Cell Interactions
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text A synchronized global sweep of the internal genes of modern avian influenza virus
by Worobey, Michael and Worobey, Michael and Han, Guan-Zhu and Han, Guan-Zhu and Rambaut, Andrew and Rambaut, Andrew
Nature, ISSN 0028-0836, 2014, Volume 508, Issue 7495, pp. 254 - 257
Zoonotic infectious diseases such as influenza continue to pose a grave threat to human health(1). However, the factors that mediate the emergence of RNA... 
A VIRUS | EQUINE INFLUENZA | MAXIMUM-LIKELIHOOD | TRANSMISSION | EVOLUTION | DNA | MULTIDISCIPLINARY SCIENCES | DATES | EMERGENCE | Pandemics | Genome, Viral - genetics | Humans | Influenza A Virus, H3N8 Subtype - classification | Influenza A virus - genetics | Molecular Sequence Data | Neuraminidase - genetics | Phylogeny | Influenza A Virus, H3N8 Subtype - genetics | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Zoonoses - virology | Genes, Viral - genetics | Neuraminidase - classification | Birds - virology | Host Specificity | Influenza in Birds - transmission | Influenza A virus - enzymology | Zoonoses - transmission | Hemagglutinin Glycoproteins, Influenza Virus - classification | Animals | Influenza in Birds - virology | Influenza A Virus, H7N7 Subtype - classification | Horses - virology | Influenza A Virus, H7N7 Subtype - genetics | Influenza A virus - classification | Swine - virology | Evolution, Molecular | Distribution | Avian influenza viruses | Physiological aspects | Genetic aspects | Research | Genetic polymorphisms | Proteins | Birds | Evolution & development | Avian flu | Genes
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Adaptation of Avian Influenza A Virus Polymerase in Mammals To Overcome the Host Species Barrier
by Benjamin Mänz and Martin Schwemmle and Linda Brunotte
Journal of Virology, ISSN 0022-538X, 07/2013, Volume 87, Issue 13, pp. 7200 - 7209
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
NUCLEAR IMPORT | PA SUBUNIT | VIRAL-RNA REPLICATION | RIBONUCLEOPROTEIN COMPLEXES | VIROLOGY | AMINO-ACID-RESIDUES | PB2 PROTEIN | PANDEMIC H1N1 | CAP-BINDING | C-TERMINAL DOMAIN | H5N1 INFLUENZA | Species Specificity | Virus Replication - genetics | Adaptation, Biological - genetics | Humans | Nucleoproteins - genetics | Viral Proteins - genetics | Birds | DNA-Directed RNA Polymerases - genetics | Influenza A virus - enzymology | Mutation - genetics | Viral Proteins - metabolism | Animals | Host-Pathogen Interactions - genetics | Models, Biological | Influenza in Birds - virology | DNA-Directed RNA Polymerases - metabolism | Virus Replication - physiology | Minireview
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text The Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug Design
by Stevaert, Annelies and Naesens, Lieve
Medicinal Research Reviews, ISSN 0198-6325, 11/2016, Volume 36, Issue 6, pp. 1127 - 1173
Influenza viruses cause seasonal epidemics and pandemic outbreaks associated with significant morbidity and mortality, and a huge cost. Since resistance to the... 
influenza virus | polymerase | antiviral | cap‐snatching | nucleoside | cap-snatching | CHEMISTRY, MEDICINAL | DEPENDENT RNA-POLYMERASE | PROTEIN-PROTEIN INTERACTION | A-VIRUS | CAP-BINDING-PROTEIN | VITRO BIOLOGICAL EVALUATION | IN-VITRO | STRUCTURE-BASED DISCOVERY | SMALL-MOLECULE INHIBITORS | N-TERMINAL DOMAIN | PHARMACOLOGY & PHARMACY | PA ENDONUCLEASE DOMAIN | Influenza B virus - enzymology | Antiviral Agents - pharmacology | Viral Proteins - chemistry | Humans | RNA Replicase - metabolism | Models, Molecular | Influenza A virus - enzymology | Viral Proteins - metabolism | Viral Nonstructural Proteins - chemistry | Animals | Antiviral Agents - chemistry | Influenza A Virus, H1N1 Subtype - enzymology | RNA Replicase - chemistry | Viral Nonstructural Proteins - metabolism | Influenza viruses | Antiviral agents | Synthesis | RNA | Influenza | Health aspects | Protein-protein interactions | Review
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights