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1. Full Text A pharmacologically immunosuppressed mouse model for assessing influenza B virus pathogenicity and oseltamivir treatment
by Marathe, Bindumadhav M and Mostafa, Heba H and Vogel, Peter and Pascua, Philippe Noriel Q and Jones, Jeremy C and Russell, Charles J and Webby, Richard J and Govorkova, Elena A
Antiviral Research, ISSN 0166-3542, 12/2017, Volume 148, pp. 20 - 31
Immunocompromised patients are highly susceptible to influenza virus infections. Although neuraminidase inhibitor (NAI) therapy has proved effective in these... 
Oseltamivir | Influenza B virus | Immune responses | Antiviral treatment | Pathogenesis | Immunosuppressed mice | UNITED-STATES | ANTIVIRAL THERAPY | ADULTS | TRANSPLANT RECIPIENTS | CHILDREN | VIROLOGY | HIGH-DOSE CYCLOPHOSPHAMIDE | DISEASE | ANIMAL-MODELS | CHRONIC LYMPHOCYTIC-LEUKEMIA | PHARMACOLOGY & PHARMACY | INFECTION | Virulence - drug effects | Orthomyxoviridae Infections - physiopathology | Oseltamivir - therapeutic use | Humans | Lung - virology | Madin Darby Canine Kidney Cells | Influenza B virus - immunology | Influenza B virus - drug effects | Orthomyxoviridae Infections - drug therapy | Oseltamivir - pharmacology | Disease Models, Animal | Influenza B virus - classification | Cell Line | Virus Replication - drug effects | Antiviral Agents - pharmacology | Lung - pathology | Antiviral Agents - therapeutic use | Influenza B virus - pathogenicity | Treatment Outcome | Virus Replication - immunology | Lung - physiopathology | Viral Load - immunology | Animals | Virulence - immunology | Dogs | Neuraminidase - antagonists & inhibitors | Mice | Mice, Inbred BALB C | Immunocompromised Host | Viral Load - drug effects | Orthomyxoviridae Infections - virology | Lung - immunology | Orthomyxoviridae Infections - immunology | Influenza viruses | Medical research | Oseltamivir phosphate | Immune response | Analysis | Influenza | Medicine, Experimental | Disease susceptibility | Health aspects
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2. Full Text IFITM3 restricts the morbidity and mortality associated with influenza
by Everitt, Aaron R and Clare, Simon and Pertel, Thomas and John, Sinu P and Wash, Rachael S and Smith, Sarah E and Chin, Christopher R and Feeley, Eric M and Sims, Jennifer S and Adams, David J and Wise, Helen M and Kane, Leanne and Goulding, David and Digard, Paul and Anttila, Verneri and Baillie, J. Kenneth and Walsh, Tim S and Hume, David A and Palotie, Aarno and Xue, Yali and Colonna, Vincenza and Tyler-Smith, Chris and Dunning, Jake and Gordon, Stephen B and Smyth, Rosalind L and Openshaw, Peter J and Dougan, Gordon and Brass, Abraham L and Kellam, Paul and MOSAIC Investigators and GenISIS Investigators and The GenISIS Investigators and The MOSAIC Investigators
Nature, ISSN 0028-0836, 04/2012, Volume 484, Issue 7395, pp. 519 - 523
The 2009 H1N1 influenza pandemic showed the speed with which a novel respiratory virus can spread and the ability of a generally mild infection to induce... 
PATHOGENESIS | WEST NILE VIRUS | INFECTION | PROTEINS | MULTIDISCIPLINARY SCIENCES | Analysis | Mortality | Swine influenza | United Kingdom | Research | Morbidity | Membrane proteins | Pathology | Pandemics | Lymphocytes | Viruses | Genomes | Avian flu | Blood | Viral infections | Apoptosis
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3. Full Text Time Lines of Infection and Disease in Human Influenza: A Review of Volunteer Challenge Studies
by Carrat, Fabrice and Vergu, Elisabeta and Ferguson, Neil M and Lemaitre, Magali and Cauchemez, Simon and Leach, Steve and Valleron, Alain-Jacques
American Journal of Epidemiology, ISSN 0002-9262, 4/2008, Volume 167, Issue 7, pp. 775 - 785
The dynamics of viral shedding and symptoms following influenza virus infection are key factors when considering epidemic control measures. The authors... 
Virus shedding | Influenza, human | Signs and symptoms | influenza | SERONEGATIVE ADULT VOLUNTEERS | UNITED-STATES | REASSORTANT VIRUS | UPPER RESPIRATORY-TRACT | signs and symptoms | PANDEMIC INFLUENZA | AMANTADINE HYDROCHLORIDE | virus shedding | TEMPERATURE-SENSITIVE MUTANTS | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | A VIRUS-INFECTION | WILD-TYPE VIRUS | ADAPTED RECOMBINANT VIRUSES | human | Humans | Influenza A Virus, H3N2 Subtype - pathogenicity | Influenza B virus - pathogenicity | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza, Human - epidemiology | Influenza Vaccines | Virus Shedding | Influenza, Human - prevention & control | Influenza, Human - immunology | Influenza viruses | Influenza | Physiological aspects | Development and progression | Influence | Diagnosis | Research | Epidemiology | Disease transmission | Virology
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4. Full Text Insights into the Interaction between Influenza Virus and Pneumococcus
by Jonathan A. McCullers
Clinical Microbiology Reviews, ISSN 0893-8512, 07/2006, Volume 19, Issue 3, pp. 571 - 582
Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
A VIRUS | GROWTH-FACTOR-BETA | TOLL-LIKE RECEPTOR-4 | STREPTOCOCCUS-PNEUMONIAE | POLYMORPHONUCLEAR LEUKOCYTE DYSFUNCTION | ACUTE OTITIS-MEDIA | MICROBIOLOGY | CHOLINE-BINDING-PROTEINS | SECONDARY BACTERIAL PNEUMONIA | PLATELET-ACTIVATING-FACTOR | LARGE-SCALE INTERVENTION | Pneumonia, Pneumococcal - complications | Pneumonia, Pneumococcal - microbiology | Streptococcus pneumoniae - pathogenicity | Humans | Influenza B virus - pathogenicity | Influenza, Human - mortality | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza, Human - virology | Influenza, Human - complications | Pneumonia, Pneumococcal - mortality | Influenza A Virus, H3N8 Subtype - pathogenicity | Reviews
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5. Full Text Integrating influenza antigenic dynamics with molecular evolution
by Bedford, Trevor and Suchard, Marc A and Lemey, Philippe and Dudas, Gytis and Gregory, Victoria and Hay, Alan J and McCauley, John W and Russell, Colin A and Smith, Derek J and Rambaut, Andrew
eLife, ISSN 2050-084X, 02/2014, Volume 2014, Issue 3, p. e01914
Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype... 
SEQUENCE-ANALYSIS | B VIRUSES | AMINO-ACID | UNITED-KINGDOM | A H1N1 VIRUSES | GENOMIC ANALYSES | VARIANTS | BIOLOGY | HEMAGGLUTININ GENE | EPIDEMIC INFLUENZA | DRIFT | Influenza A Virus, H1N1 Subtype - immunology | Genetic Drift | Antigens, Viral - metabolism | Humans | Virulence | Influenza A Virus, H3N2 Subtype - metabolism | Antigens, Viral - genetics | Influenza A Virus, H3N2 Subtype - genetics | Phylogeny | Influenza B virus - genetics | Time Factors | Influenza Vaccines - therapeutic use | Influenza, Human - virology | Influenza B virus - immunology | Seasons | Influenza A Virus, H1N1 Subtype - genetics | Influenza A Virus, H1N1 Subtype - metabolism | Influenza A Virus, H3N2 Subtype - pathogenicity | Influenza B virus - pathogenicity | Genotype | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza, Human - epidemiology | Influenza A Virus, H3N2 Subtype - immunology | Antigens, Viral - immunology | Phenotype | Influenza Vaccines - immunology | Influenza B virus - metabolism | Models, Genetic | Influenza, Human - prevention & control | Evolution, Molecular | Influenza, Human - immunology | Cartography | Cross-reactivity | Antigenic drift | Viruses | Infections | Vaccines | Hemagglutination inhibition | Virology | Molecular evolution | Genotype & phenotype | Hemagglutination | Influenza | Phylogenetics | Population | Evolution | Drift | Mutation | Evolution & development | Strains (organisms) | Public health
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6. Full Text Predicting the epidemic sizes of influenza A/H1N1, A/H3N2, and B: A statistical method
by Goldstein, Edward and Cobey, Sarah and Takahashi, Saki and Miller, Joel C and Lipsitch, Marc
PLoS Medicine, ISSN 1549-1277, 07/2011, Volume 8, Issue 7, p. e1001051
Background: The epidemic sizes of influenza A/H3N2, A/H1N1, and B infections vary from year to year in the United States. We use publicly available US Centers... 
VACCINATION | MEDICINE, GENERAL & INTERNAL | INFECTION | VIRUS | EVOLUTION | United States - epidemiology | Humans | Influenza A Virus, H3N2 Subtype - pathogenicity | Influenza B virus - pathogenicity | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza, Human - epidemiology | Models, Statistical | Centers for Disease Control and Prevention (U.S.) | Forecasting | Epidemics - statistics & numerical data | Incidence | Influenza, Human - virology | Seasons | Population Surveillance - methods | Epidemics | Research | United States | Influenza | Risk factors | Illnesses | Pandemics | Calendars | Viruses | Infections | Disease control | Viral infections
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7. Full Text The roles of hemagglutinin Phe-95 in receptor binding and pathogenicity of influenza B virus
by Ni, Fengyun and Nnadi Mbawuike, Innocent and Kondrashkina, Elena and Wang, Qinghua and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Virology, ISSN 0042-6822, 2013, Volume 450, Issue C, pp. 71 - 83
Abstract Diverged ~4000 years ago, influenza B virus has several important differences from influenza A virus, including lower receptor-binding affinity and... 
Infectious Disease | Pathogenicity | Host range | Receptor-binding affinity | Hemagglutinin | Influenza virus | GLYCOSYLATION SITE | SPECIFICITY | PANDEMIC INFLUENZA | H1N1 | A VIRUS | REPLICATION | VIROLOGY | STRUCTURAL BASIS | ADAPTATION | MEMBRANE GLYCOPROTEIN | SELECTION | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Phenylalanine - metabolism | Receptors, Virus - metabolism | Humans | Influenza A virus - genetics | Virulence | Influenza B virus - pathogenicity | Models, Molecular | Receptors, Virus - genetics | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Amino Acid Motifs | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Influenza B virus - genetics | Animals | Influenza A virus - metabolism | Phenylalanine - genetics | Protein Binding | Female | Influenza B virus - chemistry | Influenza B virus - metabolism | Mice, Inbred BALB C | Lectins | Chemical properties | Hydrogen | Influenza | influenza virus | pathogenicity | receptor-binding affinity | hemagglutinin | host range
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8. Full Text The M2 proton channels of influenza A and B viruses
by Pinto, Lawrence H and Lamb, Robert A
Journal of Biological Chemistry, ISSN 0021-9258, 04/2006, Volume 281, Issue 14, pp. 8997 - 9000
NUCLEAR TRANSPORT | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSMEMBRANE DOMAIN | CELL-SURFACE | BM2 PROTEIN | AMANTADINE | M PROTEIN | M-2 ION-CHANNEL | SELECTIVITY | PLANAR LIPID-BILAYERS | INTEGRAL MEMBRANE-PROTEIN | Influenza A virus - physiology | Antiviral Agents - pharmacology | Virus Replication | Viral Proteins - physiology | Influenza A virus - pathogenicity | Influenza B virus - pathogenicity | Structure-Activity Relationship | Influenza B virus - physiology | Viral Matrix Proteins - physiology | Amantadine - pharmacology
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9. Full Text Excess Mortality associated with influenza A and B virus in Hong Kong, 1998-2009
by Wu, Peng and Goldstein, Edward and Ho, Lai Ming and Yang, Lin and Nishiura, Hiroshi and Wu, Joseph T and Ip, Dennis K. M and Chuang, Shuk-Kwan and Tsang, Thomas and Cowling, Benjamin J
Journal of Infectious Diseases, ISSN 0022-1899, 12/2012, Volume 206, Issue 12, pp. 1862 - 1871
Background. Although deaths associated with laboratory-confirmed influenza virus infections are rare, the excess mortality burden of influenza estimated from... 
UNITED-STATES | INFECTIOUS DISEASES | SURVEILLANCE DATA | VACCINATION | MICROBIOLOGY | DEATHS | IMMUNOLOGY | PNEUMONIA | SEASONAL INFLUENZA | DISEASE | ACUTE MYOCARDIAL-INFARCTION | INFECTION | RESPIRATORY SYNCYTIAL VIRUS | United States - epidemiology | Age Factors | Influenza B virus - isolation & purification | Humans | Middle Aged | Child, Preschool | Influenza B virus - pathogenicity | Infant | Influenza, Human - epidemiology | Male | Influenza A virus - isolation & purification | Mortality - trends | Young Adult | Hong Kong - epidemiology | Adolescent | Aged, 80 and over | Influenza A virus - pathogenicity | Influenza, Human - mortality | Adult | Female | Influenza, Human - virology | Aged | Child | Infant, Newborn | Major and Brief Reports
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10. Full Text Susceptibility of influenza viruses to hypothiocyanite and hypoiodite produced by lactoperoxidase in a cell-free system
by Patel, Urmi and Gingerich, Aaron and Widman, Lauren and Sarr, Demba and Tripp, Ralph A and Rada, Balázs
PLoS ONE, ISSN 1932-6203, 07/2018, Volume 13, Issue 7, p. e0199167
Lactoperoxidase (LPO) is an enzyme found in several exocrine secretions including the airway surface liquid producing antimicrobial substances from mainly... 
A VIRUS | INACTIVATION | AIRWAY | EPITHELIAL-CELLS | HEMAGGLUTININ | MULTIDISCIPLINARY SCIENCES | IODIDE | B VIRUS | DUAL OXIDASE | Thiocyanates - metabolism | Influenza A Virus, H3N2 Subtype - drug effects | Humans | Cell-Free System - drug effects | Substrate Specificity | Iodine Compounds - metabolism | Thiocyanates - chemistry | Iodine Compounds - chemistry | Antiviral Agents - chemistry | Madin Darby Canine Kidney Cells | Thiocyanates - pharmacology | Influenza, Human - virology | Orthomyxoviridae - drug effects | Influenza B virus - drug effects | Influenza, Human - drug therapy | Lactoperoxidase - chemistry | Antiviral Agents - pharmacology | Iodine Compounds - pharmacology | Influenza A Virus, H3N2 Subtype - pathogenicity | Influenza B virus - pathogenicity | Influenza A Virus, H1N1 Subtype - pathogenicity | Lactoperoxidase - metabolism | Influenza A Virus, H1N1 Subtype - drug effects | Animals | Dogs | Orthomyxoviridae - pathogenicity | Influenza viruses | Oxidases | Research | Analysis | Immune system | Glucose oxidase | Veterinary colleges | Hydrogen peroxide | Immune response | Pandemics | Deactivation | Iodides | Cell-free system | Viruses | Vaccines | Glucose | Secretions | Drug resistance | Inactivation | Antiinfectives and antibacterials | Substrates | Respiratory tract | Substrate specificity | Influenza | Substrate preferences | Thiocyanates | Influenza A | Strains (organisms) | Influenza B
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11. Full Text Exposure to common respiratory bacteria alters the airway epithelial response to subsequent viral infection
by Bellinghausen, Carla and Gulraiz, Fahad and