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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 12/2013, Volume 21, Issue 24, pp. 7938 - 7954
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 09/2013, Volume 21, Issue 18, pp. 5725 - 5737
Journal Article
Journal Article
Science, ISSN 0036-8075, 10/2011, Volume 334, Issue 6054, pp. 376 - 380
Journal Article
Immunity, ISSN 1074-7613, 02/2012, Volume 36, Issue 2, pp. 215 - 227
Interleukin-1β (IL-1β) is a potent inflammatory cytokine that is usually cleaved and activated by inflammasome-associated caspase-1. To determine whether IL-1β... 
STERILE INFLAMMATORY RESPONSE | PROGRAMMED NECROSIS | CASPASE-8 | IL-1-BETA | NLRP3 INFLAMMASOME | TNF-ALPHA | IMMUNOLOGY | NF-KAPPA-B | CIAP1 | NALP3 INFLAMMASOME | CELL-DEATH | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | X-Linked Inhibitor of Apoptosis Protein - deficiency | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Inhibitor of Apoptosis Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Caspase 1 - metabolism | Baculoviral IAP Repeat-Containing 3 Protein | Mitochondrial Proteins - agonists | Carrier Proteins - agonists | Inhibitor of Apoptosis Proteins - deficiency | Molecular Mimicry | Interleukin-1beta - metabolism | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Inhibitor of Apoptosis Proteins - metabolism | Macrophages - immunology | Macrophages - cytology | X-Linked Inhibitor of Apoptosis Protein - genetics | Mice, Knockout | Ubiquitin-Protein Ligases | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Inflammasomes - immunology | X-Linked Inhibitor of Apoptosis Protein - metabolism | Macrophages - drug effects | Mice | Apoptosis | Proteins | Interleukins | Genes | Membranes | Mammals | Immune system | Caspase-8 | DIABLO protein | Cell activation | IAP protein | Reactive oxygen species | Interleukin 1 | Toll-like receptors | XIAP protein | Inflammation | Macrophages | Caspase-1 | Index Medicus
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2012, Volume 55, Issue 9, pp. 4101 - 4113
Journal Article
Journal Article
Journal Article
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 2/2013, Volume 62, Issue 2, pp. 321 - 335
Inhibitor of apoptosis proteins (IAPs) are critical in regulating apoptosis resistance in cancer. Antagonists of IAPs, such as LCL161, are in clinical... 
Cross-presentation | Dendritic cell | Immunology | Medicine & Public Health | IAP antagonist | Oncology | Cancer Research | Immunomodulatory | SMAC mimetic | ACTIVATION | SMAC MIMETICS | IMMUNOLOGY | TUMOR-ANTIGEN | ONCOLOGY | DENDRITIC CELL-DEVELOPMENT | ALPHA-DEPENDENT APOPTOSIS | TNF-ALPHA | NF-KAPPA-B | T-CELLS | ANTIGEN DELIVERY | Leukocytes, Mononuclear - drug effects | Antigens, Neoplasm - immunology | Apoptosis - drug effects | Cancer Vaccines - pharmacology | Dendritic Cells - immunology | Humans | Cells, Cultured | Cytokines - secretion | NF-kappa B - metabolism | Combined Modality Therapy | Peptides - pharmacology | Up-Regulation - drug effects | T-Lymphocytes - drug effects | Immunotherapy | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Leukocytes, Mononuclear - immunology | Antigens, Neoplasm - pharmacology | Dendritic Cells - drug effects | T-Lymphocytes - immunology | Antineoplastic Agents - pharmacology | Thiazoles - pharmacology | Proteins | Care and treatment | Dendritic cells | Universities and colleges | T cells | Cancer | Tumors | Apoptosis | Index Medicus | IAP protein | Cell survival | Cytokines | CD8 antigen | Immunomodulation | Tumor cells | Data processing | Antagonists | Lymphocytes T | CD4 antigen | Cancer vaccines | Antagonism | Cell activation | NF- Kappa B protein | Peripheral blood mononuclear cells | synthetic peptides
Journal Article
Nature Medicine, ISSN 1078-8956, 12/2016, Volume 22, Issue 12, pp. 1411 - 1420
Journal Article