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1. Full Text The inhibitors of apoptosis (IAPs) as cancer targets
by Hunter, Allison M and LaCasse, Eric C and Korneluk, Robert G
Apoptosis (London), ISSN 1360-8185, 9/2007, Volume 12, Issue 9, pp. 1543 - 1568
Biochemistry, general | TNFR | TRAF | Oncology | NFkB | Virology | Cell Biology | Biomedicine | Cancer Research | IAPs | Caspases | Smac | Knock out mice | Apoptosis | Cancer | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Caspases - physiology | Proto-Oncogene Proteins c-bcl-2 - physiology | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | Humans | Neoplasm Proteins - physiology | Serine Endopeptidases - physiology | Neoplasm Proteins - antagonists & inhibitors | Inhibitor of Apoptosis Proteins - physiology | X-Linked Inhibitor of Apoptosis Protein - antagonists & inhibitors | Neoplasms - genetics | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Oligonucleotides, Antisense - therapeutic use | Intracellular Signaling Peptides and Proteins - therapeutic use | Mitochondrial Proteins - therapeutic use | Peptide Termination Factors - physiology | Mitochondrial Proteins - physiology | Neoplasm Proteins - therapeutic use | Microtubule-Associated Proteins - antagonists & inhibitors | Caspase Inhibitors | High-Temperature Requirement A Serine Peptidase 2 | Neoplasms - drug therapy | Animals | Protein Kinases - physiology | Checkpoint Kinase 1 | Enzyme Activation | Genetic Vectors | Intracellular Signaling Peptides and Proteins - physiology | Proteins | Cancer therapies | Index Medicus
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2. Full Text The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs
by Tenev, Tencho and Bianchi, Katiuscia and Darding, Maurice and Broemer, Meike and Langlais, Claudia and Wallberg, Fredrik and Zachariou, Anna and Lopez, Juanita and MacFarlane, Marion and Cain, Kelvin and Meier, Pascal
Molecular cell, ISSN 1097-2765, 08/2011, Volume 43, Issue 3, pp. 432 - 448
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | CASP8 and FADD-Like Apoptosis Regulating Protein - physiology | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | Humans | Caspase 8 - metabolism | Nuclear Pore Complex Proteins - chemistry | Caspase 8 - chemistry | Inhibitor of Apoptosis Proteins - physiology | Nuclear Pore Complex Proteins - physiology | Antineoplastic Agents - pharmacology | CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism | Fas-Associated Death Domain Protein - physiology | RNA-Binding Proteins - physiology | Signal Transduction | CASP8 and FADD-Like Apoptosis Regulating Protein - genetics | Nuclear Pore Complex Proteins - metabolism | RNA-Binding Proteins - chemistry | Fas-Associated Death Domain Protein - metabolism | Etoposide - pharmacology | Mitochondria - metabolism | Caspase 8 - physiology | Fas-Associated Death Domain Protein - chemistry | Cell Line, Tumor | Ligands | Apoptosis - physiology | DNA Damage | Enzyme Activation | RNA-Binding Proteins - metabolism | Ubiquitin | Green design | Oncology, Experimental | Internet service providers | Research | Sustainable development | Cancer | Index Medicus
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3. Full Text miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes
by Qian, Li and Van Laake, Linda W and Huang, Yu and Liu, Siyuan and Wendland, Michael F and Srivastava, Deepak
The Journal of experimental medicine, ISSN 0022-1007, 03/2011, Volume 208, Issue 3, pp. 549 - 560
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Myocardial Infarction - genetics | Myocardial Ischemia - metabolism | Apoptosis - genetics | Flow Cytometry | Bcl-2-Like Protein 11 | Membrane Proteins - physiology | Myocardial Ischemia - physiopathology | Myocardial Infarction - physiopathology | Disease Models, Animal | Proto-Oncogene Proteins - antagonists & inhibitors | Gene Expression Regulation - genetics | Gene Expression Regulation - physiology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Down-Regulation - genetics | Down-Regulation - physiology | Animals | Membrane Proteins - antagonists & inhibitors | Myocytes, Cardiac - physiology | Apoptosis Regulatory Proteins - antagonists & inhibitors | Proto-Oncogene Proteins - physiology | Myocytes, Cardiac - metabolism | Apoptosis Regulatory Proteins - physiology | Mice | MicroRNAs - genetics | Apoptosis - physiology | MicroRNAs - physiology | Index Medicus
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4. Full Text Targeting IAP proteins for therapeutic intervention in cancer
by Fulda, Simone and Vucic, Domagoj
Nature reviews. Drug discovery, ISSN 1474-1776, 02/2012, Volume 11, Issue 2, pp. 109 - 124
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Oligodeoxyribonucleotides, Antisense - pharmacology | X-Linked Inhibitor of Apoptosis Protein - drug effects | Apoptosis - drug effects | Humans | Oligodeoxyribonucleotides, Antisense - therapeutic use | Antineoplastic Agents - therapeutic use | Inhibitor of Apoptosis Proteins - physiology | Neoplasms - drug therapy | Animals | Cell Death - physiology | Signal Transduction - drug effects | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Inhibitor of Apoptosis Proteins - drug effects | Signal Transduction - physiology | Antineoplastic Agents - pharmacology | Apoptosis - physiology | Cell Death - drug effects | Drug Therapy, Combination | X-Linked Inhibitor of Apoptosis Protein - physiology | Physiological aspects | Research | Gene expression | Cancer cells | Apoptosis | Index Medicus
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5. Full Text ABINs: A20 binding inhibitors of NF-κB and apoptosis signaling
by Verstrepen, Lynn and Carpentier, Isabelle and Verhelst, Kelly and Beyaert, Rudi
Biochemical pharmacology, ISSN 0006-2952, 2009, Volume 78, Issue 2, pp. 105 - 114
ABIN | NF-κB | Inflammation | Apoptosis | A20 | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Humans | Molecular Sequence Data | NF-kappa B - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | DNA-Binding Proteins - metabolism | Apoptosis Regulatory Proteins - genetics | Tumor Necrosis Factor alpha-Induced Protein 3 | Amino Acid Sequence | Proteins - physiology | DNA-Binding Proteins - physiology | NF-kappa B - antagonists & inhibitors | Apoptosis Regulatory Proteins - chemistry | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Apoptosis Regulatory Proteins - metabolism | Proteins - genetics | Adaptor Proteins, Signal Transducing - physiology | Animals | Proteins - metabolism | Adaptor Proteins, Signal Transducing - genetics | Apoptosis Regulatory Proteins - physiology | Signal Transduction - physiology | Adaptor Proteins, Signal Transducing - biosynthesis | Apoptosis - physiology | Proteins - chemistry | Adaptor Proteins, Signal Transducing - metabolism | Protein Binding - physiology | Index Medicus
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