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Nature, ISSN 0028-0836, 03/2014, Volume 507, Issue 7493, pp. 513 - 8
Journal Article
Nature, ISSN 0028-0836, 10/2012, Volume 490, Issue 7418, pp. 116 - 120
Journal Article
Science, ISSN 0036-8075, 09/2016, Volume 353, Issue 6304, pp. aaf4238 - aaf4238
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 06/2012, Volume 21, Issue 6, pp. 777 - 792
There is increasing evidence that some cancers are hierarchically organized, sustained by a relatively rare population of cancer-initiating cells (C-ICs).... 
HUMAN COLORECTAL-CARCINOMA | STEM-CELLS | ONCOLOGY | INDUCED APOPTOSIS | PROTECTIVE ROLE | PROSTATE-CANCER | DNA-DAMAGE | ACUTE MYELOID-LEUKEMIA | ID-1 PROTEIN | EXPRESSION | HUMAN PANCREATIC-CANCER | CELL BIOLOGY | Cell Cycle - genetics | Colonic Neoplasms - genetics | Neoplastic Stem Cells - drug effects | Colonic Neoplasms - drug therapy | Humans | Gene Expression Regulation, Neoplastic | Spheroids, Cellular - pathology | Inhibitor of Differentiation Proteins - genetics | Neoplasm Proteins - metabolism | Organoplatinum Compounds - pharmacology | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Neoplastic Stem Cells - metabolism | RNA Interference | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Neoplastic Stem Cells - pathology | Antineoplastic Agents - pharmacology | Spheroids, Cellular - drug effects | Tumor Cells, Cultured | Neoplasm Proteins - genetics | Spheroids, Cellular - metabolism | Inhibitor of Differentiation Proteins - metabolism | Inhibitor of Differentiation Protein 1 - metabolism | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Xenograft Model Antitumor Assays | Microscopy, Confocal | Animals | Colonic Neoplasms - pathology | Inhibitor of Differentiation Protein 1 - genetics | Mice, Inbred NOD | Cell Proliferation - drug effects | Mice | Cell Cycle - drug effects | Chemotherapy | Genes | Cancer | Tumors
Journal Article
Biochimie, ISSN 0300-9084, 05/2015, Volume 112, pp. 139 - 150
The four known ID proteins (ID1-4, Inhibitor of Differentiation) share a homologous helix loop helix (HLH) domain and act as dominant negative regulators of... 
ID4 | DNA-Protein interaction | Protein–protein interaction | Tumor suppressor gene | Cancer | Protein-protein interaction | DOXORUBICIN-INDUCED APOPTOSIS | UNFAVORABLE PROGNOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-SUPPRESSOR GENES | POOR DIFFERENTIATION | CELLULAR SENESCENCE | NEGATIVE REGULATOR | BREAST-CANCER | EPIGENETIC INACTIVATION | PROSTATE-CANCER CELLS | EXPRESSION PATTERN | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - pathology | Basic Helix-Loop-Helix Transcription Factors - genetics | Humans | Inhibitor of Differentiation Proteins - genetics | Inhibitor of Differentiation Protein 1 - antagonists & inhibitors | Male | Neoplasm Proteins - antagonists & inhibitors | Inhibitor of Differentiation Proteins - metabolism | Inhibitor of Differentiation Protein 1 - metabolism | Neoplasm Proteins - metabolism | Inhibitor of Differentiation Protein 2 - metabolism | Inhibitor of Differentiation Proteins - antagonists & inhibitors | Prostatic Neoplasms - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Inhibitor of Differentiation Protein 2 - genetics | Cell Line, Tumor | Inhibitor of Differentiation Protein 1 - genetics | Inhibitor of Differentiation Protein 2 - antagonists & inhibitors | Transcription, Genetic | Neoplasm Proteins - genetics | Proteins | DNA | Genetic research | Genetic aspects | Genetic transcription | Prostate cancer | DNA-ligand interactions | protein-protein interaction | cancer | DNA-protein interaction | tumor suppressor gene
Journal Article
Diabetologia, ISSN 0012-186X, 4/2015, Volume 58, Issue 4, pp. 758 - 770
Oxidative stress is implicated in beta cell glucotoxicity in type 2 diabetes. Inhibitor of differentiation (ID) proteins are transcriptional regulators induced... 
Type 2 diabetes | Oxidative stress | Reactive oxygen species | Medicine & Public Health | Human Physiology | Metabolic Diseases | Beta cell | Internal Medicine | Islets of Langerhans | Apoptosis | INSULIN-SECRETION | ID PROTEINS | MODEL | CHRONIC HYPERGLYCEMIA | GLUCOSE REGULATION | DIABETIC-PATIENTS | PANCREATIC-ISLETS | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | UP-REGULATION | Oxidative Stress | Diabetes Mellitus - genetics | Antioxidants - metabolism | Inhibitor of Differentiation Proteins - genetics | Inhibitor of Differentiation Protein 1 - deficiency | Insulin-Secreting Cells - metabolism | Maf Transcription Factors, Small - genetics | Transfection | RNA Interference | Time Factors | NF-E2-Related Factor 2 - genetics | Disease Models, Animal | Inhibitor of Differentiation Proteins - deficiency | Cell Line | Signal Transduction | Tissue Culture Techniques | Mice, Inbred C57BL | Gene Expression Regulation | Diabetes Mellitus - metabolism | Inhibitor of Differentiation Proteins - metabolism | Mitochondria - metabolism | Inhibitor of Differentiation Protein 1 - metabolism | Mice, Knockout | Animals | NF-E2-Related Factor 2 - metabolism | Inhibitor of Differentiation Protein 1 - genetics | Maf Transcription Factors, Small - metabolism | Antioxidants | Proteins | Pancreatic beta cells | Hyperglycemia | Sugars | Monosaccharides
Journal Article