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PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, pp. e41576 - e41576
Post-transcriptional events play an important role in human development. The question arises as to whether Adenosine to Inosine RNA editing, catalyzed by the... 
BINDING DOMAINS | ADENOSINE-DEAMINASE | GENE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | INOSINE RNA | HUMAN TRANSCRIPTOME | NUCLEAR RETENTION | EXPRESSION | ADAR1 | PRE-MESSENGER-RNA | Inosine - genetics | Contractile Proteins - genetics | Adenosine Deaminase - metabolism | RNA Editing | Humans | RNA-Binding Proteins | Fanconi Anemia Complementation Group C Protein - genetics | RNA, Messenger - metabolism | Adenosine - genetics | CARD Signaling Adaptor Proteins - genetics | Protein Isoforms - metabolism | Gene Expression Regulation, Developmental | Cell Cycle Proteins - genetics | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Microfilament Proteins - genetics | Gene Expression | Adenosine Deaminase - genetics | RNA, Messenger - genetics | Cells, Cultured | Embryonal Carcinoma Stem Cells | Inosine - metabolism | Proto-Oncogene Proteins - genetics | Embryonic Development | Filamins | BRCA1 Protein - genetics | Adaptor Proteins, Signal Transducing - genetics | Adenosine - metabolism | Guanylate Cyclase - genetics | Embryonic Stem Cells | Alu Elements | Protein Isoforms - genetics | Enzymes | Embryonic development | Adenosine | RNA | Analysis | Genes | T cells | Embryonic stem cells | Health aspects | Brain | Post-transcription | Liver | Embryo cells | Editing | Infections | Tissues | Human tissues | Gene sequencing | Proteins | Embryogenesis | Transfection | Developmental stages | Coding | Rodents | Cell cycle | Spleen | Medical research | RNA editing | Kidneys | BRCA1 protein | Fetuses | Gynecology | Breast cancer | Adenosine deaminase | Obstetrics | 1-Phosphatidylinositol 3-kinase | Embryonic growth stage | Medicine | Studies | Brain research | Ribonucleic acids | Biopsy | Stem cells | Alu elements | Pluripotency | Kidney transplantation | Cancer | Index Medicus
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 10/2016, Volume 22, Issue 10, pp. 1140 - 1150
Adenosine-to-inosine (A-to-I) RNA editing, which is catalyzed by a family of adenosine deaminase acting on RNA (ADAR) enzymes, is important in the... 
MEDICINE, RESEARCH & EXPERIMENTAL | ANGIOGENESIS | STABILIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | LUNG INJURY | CELL BIOLOGY | MESSENGER-RNA | GENE-EXPRESSION | ALU ELEMENTS | HUMAN TRANSCRIPTOME | BINDING PROTEIN HUR | TUMOR-GROWTH | ENZYME ADAR1 | Human Umbilical Vein Endothelial Cells | RNA-Binding Proteins - genetics | RNA Editing - genetics | Atherosclerosis - genetics | Humans | Middle Aged | Immunoblotting | Male | RNA, Messenger - metabolism | Gene Knockdown Techniques | Aged, 80 and over | Adult | Female | 3' Untranslated Regions | Real-Time Polymerase Chain Reaction | Adenosine Deaminase - genetics | RNA Processing, Post-Transcriptional - drug effects | ELAV-Like Protein 1 - genetics | Gene Expression Regulation | Inosine - metabolism | Gene Knock-In Techniques | Tumor Necrosis Factor-alpha - pharmacology | Hypoxia - genetics | RNA Processing, Post-Transcriptional - genetics | Sequence Analysis, RNA | Cathepsins - genetics | Carotid Artery Diseases - genetics | Coronary Artery Disease - genetics | Fluorescent Antibody Technique | Adenosine - metabolism | Aged | High-Throughput Nucleotide Sequencing | Aortic Aneurysm - genetics | Interferon-gamma - pharmacology | RNA Editing - drug effects | Adenosine | Atherosclerosis | Genetic aspects | Dosage and administration | Research | Gene expression | Drug therapy | Post-transcription | Gene regulation | Cysteine proteinase | Editing | Cardiovascular disease | Proteins | Angiogenesis | Control | Vascular diseases | Aorta | Heart diseases | HuR protein | RNA editing | Cytokines | Coronary artery | Inflammation | Cathepsin S | Adenosine deaminase | Metabolism | Coronary artery disease | Substrates | Endothelial cells | RNA-binding protein | Ribonucleic acids | 3' Untranslated regions | Arteriosclerosis | Hypoxia | Control stability | Interferon | mRNA stability | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 03/2010, Volume 464, Issue 7287, pp. 405 - 408
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2015, Volume 17, Issue 3, pp. 311 - 321
Although recent studies have shown that adenosine-to-inosine (A-to-I) RNA editing occurs in microRNAs (miRNAs), its effects on tumour growth and metastasis are... 
PATHWAYS | SMALL INTERFERING RNA | POLYADENYLATION | DEAMINASES | ELEMENT-BINDING PROTEIN | SYSTEMATIC IDENTIFICATION | TUMOR-GROWTH | CANCER | EXPRESSION | MODULATION | CELL BIOLOGY | Neoplasm Transplantation | RNA-Binding Proteins - genetics | Luciferases - metabolism | Adenosine Deaminase - metabolism | RNA Editing | mRNA Cleavage and Polyadenylation Factors - metabolism | Humans | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Luciferases - genetics | Neoplasm Metastasis | Melanoma - genetics | Base Sequence | Female | mRNA Cleavage and Polyadenylation Factors - genetics | Genes, Reporter | Melanoma - metabolism | Skin Neoplasms - pathology | Adenosine Deaminase - genetics | Inosine - metabolism | Melanoma - pathology | Transcription Factors - genetics | Disease Progression | Skin Neoplasms - metabolism | Transcription Factors - metabolism | Cyclic AMP Response Element-Binding Protein - genetics | Animals | Mice, Nude | MicroRNAs | Skin Neoplasms - genetics | Cyclic AMP Response Element-Binding Protein - metabolism | Adenosine - metabolism | Cell Line, Tumor | Mice | RNA-Binding Proteins - metabolism | MicroRNA | Oncology, Experimental | Melanoma | Genetic research | Development and progression | Genetic aspects | Metastasis | Research | Gene expression | Health aspects | Cancer | Index Medicus
Journal Article
Journal Article