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Journal of the American Heart Association, ISSN 2047-9980, 02/2013, Volume 2, Issue 1, pp. e003277 - n/a
Journal Article
Journal Article
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 08/2014, Volume 16, Issue 8, pp. 761 - 765
We assessed the efficacy and safety of sitagliptin compared with α‐glucosidase inhibitor ( αGI ) in 120 of Japanese patients with type 2 diabetes mellitus (... 
type 2 diabetes | DPP‐IV | inhibitor | sulphonylureas | α‐glucosidase inhibitor | randomized trial | Type 2 diabetes | Randomized trial | α-glucosidase inhibitor | Sulphonylureas | DPP-IV inhibitor | VOGLIBOSE | MONOTHERAPY | HYPERGLYCEMIA | DOUBLE-BLIND TRIAL | alpha-glucosidase inhibitor | ENDOCRINOLOGY & METABOLISM | MELLITUS | Glycated Hemoglobin A - analysis | Triazoles - adverse effects | Glycoside Hydrolase Inhibitors - adverse effects | Dipeptidyl-Peptidase IV Inhibitors - adverse effects | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Middle Aged | Glycoside Hydrolase Inhibitors - therapeutic use | Male | Pyrazines - therapeutic use | Hypoglycemia - prevention & control | 1-Deoxynojirimycin - therapeutic use | Drug Therapy, Combination - adverse effects | Inositol - therapeutic use | Inositol - adverse effects | 1-Deoxynojirimycin - analogs & derivatives | Female | 1-Deoxynojirimycin - adverse effects | Sitagliptin Phosphate | Hypoglycemia - chemically induced | Triazoles - therapeutic use | Hypoglycemic Agents - therapeutic use | Hyperglycemia - prevention & control | Japan | Sulfonylurea Compounds - therapeutic use | Inositol - analogs & derivatives | Diabetes Mellitus, Type 2 - blood | Gastrointestinal Agents - therapeutic use | Pyrazines - adverse effects | Aged | Gastrointestinal Agents - adverse effects | Diabetes Mellitus, Type 2 - drug therapy | alpha-Glucosidases - metabolism | alpha-Glucosidases - chemistry | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 11/2016, Volume 6, Issue 1, pp. 37430 - 37430
Journal Article
Toxicology Letters, ISSN 0378-4274, 09/2016, Volume 258, pp. 237 - 248
Sulfite is a compound commonly used as preservative in foods and pharmaceuticals. Many studies have examined the neurotoxicity of sulfite, but its effect on... 
Sulfite | Calcium overload | Redox | Inositol 1,4,5-triphosphate | Phospholipase C | OXIDATIVE STRESS | ACTIVATION | RAT HEPATOCYTES | OXIDASE DEFICIENCY | TOXICITY | RELEASE | NEUROTOXICITY | SIGNALING PATHWAY | CA2 | HYDROGEN-PEROXIDE | TOXICOLOGY | Antioxidants - metabolism | Oxidants - metabolism | Excipients - adverse effects | Inositol 1,4,5-Trisphosphate - antagonists & inhibitors | Male | Neurons - cytology | Cerebral Cortex - cytology | Cerebral Cortex - metabolism | Tissue Distribution | Prefrontal Cortex - drug effects | Sulfites - adverse effects | Free Radicals - metabolism | Phosphoinositide Phospholipase C - metabolism | Neurons - metabolism | Cerebral Cortex - drug effects | Neurons - drug effects | Phosphoinositide Phospholipase C - antagonists & inhibitors | Cell Survival - drug effects | Nerve Tissue Proteins - antagonists & inhibitors | Oxidation-Reduction | Cells, Cultured | Enzyme Inhibitors - pharmacology | Antioxidants - pharmacology | Oxidants - adverse effects | Prefrontal Cortex - cytology | Sulfites - metabolism | Rats, Sprague-Dawley | Free Radicals - agonists | Nerve Tissue Proteins - metabolism | Food Preservatives - metabolism | Free Radicals - antagonists & inhibitors | Animals | Calcium Signaling - drug effects | Prefrontal Cortex - metabolism | Excipients - metabolism | Antioxidants - adverse effects | Oxidative Stress - drug effects | Food Preservatives - adverse effects | Inositol 1,4,5-Trisphosphate - metabolism | Sulfites | Neurons | Nervous system diseases | Inositol | Phospholipases | Index Medicus | Depletion | Free radicals | Calcium | Homeostasis | Stores | Viability
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 08/2010, Volume 12, Issue 8, pp. 700 - 708
Journal Article
JAMA - Journal of the American Medical Association, ISSN 0098-7484, 10/2018, Volume 320, Issue 16, pp. 1649 - 1658
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 04/2012, Volume 14, Issue 4, pp. 348 - 357
Aims: To evaluate the efficacy and safety of linagliptin 5 and 10 mg vs. placebo and voglibose in Japanese patients with type 2 diabetes mellitus (T2DM).... 
glucosidase inhibitor | DPP‐4 inhibitor | glycaemic control | incretin therapy | Incretin therapy | α-glucosidase inhibitor | DPP-4 inhibitor | Glycaemic control | CONTROLLED-TRIAL | METFORMIN | DIPEPTIDYL PEPTIDASE-4 INHIBITOR | SULFONYLUREA | EFFICACY | MELLITUS | COMBINATION | a-glucosidase inhibitor | BETA-CELL FUNCTION | PHARMACOKINETICS | ENDOCRINOLOGY & METABOLISM | Dipeptidyl-Peptidase IV Inhibitors - adverse effects | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Middle Aged | Male | Purines - administration & dosage | Diabetes Mellitus, Type 2 - epidemiology | Dose-Response Relationship, Drug | Inositol - therapeutic use | Aged, 80 and over | Adult | Female | Quinazolines - administration & dosage | Linagliptin | Purines - adverse effects | Purines - therapeutic use | Hypoglycemic Agents - therapeutic use | Double-Blind Method | Drug Administration Schedule | Japan | Treatment Outcome | Inositol - analogs & derivatives | Dipeptidyl-Peptidase IV Inhibitors - administration & dosage | Blood Glucose - drug effects | Analysis of Variance | Quinazolines - therapeutic use | Quinazolines - adverse effects | Aged | Diabetes Mellitus, Type 2 - drug therapy | Type 2 diabetes | Medical colleges | Medical research | Safety and security measures | Glycosylated hemoglobin | Medicine, Experimental | Hemoglobin | Hypoglycemic agents | Universities and colleges | Diabetes | Diabetes therapy | Index Medicus
Journal Article