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PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e92142
Ceramide transfer protein (CERT) transfers ceramide from the endoplasmic reticulum (ER) to the Golgi complex. Its deficiency in mouse leads to embryonic death... 
RAT-LIVER | LIFE-SPAN | APOPTOSIS | GLUCOSYLCERAMIDE | TRANSPORT | STRUCTURAL BASIS | MULTIDISCIPLINARY SCIENCES | TRAFFICKING | ENDOPLASMIC-RETICULUM | GOLGI | CERT | Cellular Senescence - genetics | Protein-Serine-Threonine Kinases - deficiency | Gene Expression | Cell Proliferation | Ceramides - metabolism | Cell Survival | Cholera Toxin - metabolism | Embryo, Mammalian | Protein-Serine-Threonine Kinases - genetics | Endoplasmic Reticulum - metabolism | Male | Mitochondria - metabolism | Mitochondria - pathology | Fibroblasts - pathology | Mice, Knockout | Animals | Biological Transport | Endoplasmic Reticulum Stress | Female | Golgi Apparatus - metabolism | Lipid Metabolism - genetics | Mice | Primary Cell Culture | Fibroblasts - metabolism | Heart failure | Physiological aspects | Lipids | Cholera toxin | Cell death | Water-borne diseases | Reactive oxygen species | Senescence | Biosynthesis | Biology | Infections | Biochemistry | Kinases | Autophagy | Defects | Proteins | Mitochondria | Metabolites | Glutathione reductase | Rodents | Ceramide | Fibroblasts | Lipid metabolism | Protein transport | Heart diseases | Public health | Glutathione | Medical research | Toxin b | Cell division | Embryo fibroblasts | Protein deficiency | Metabolism | Mammals | Embryos | Organogenesis | Golgi apparatus | Microscopy | Insects | Green fluorescent protein | Membrane trafficking | Cholera | Laboratory animals | Endoplasmic reticulum | Viability | Apoptosis | Cancer | Reductase
Journal Article
PLoS Genetics, ISSN 1553-7390, 04/2014, Volume 10, Issue 4
  The steroid hormone ecdysone coordinates insect growth and development, directing the major postembryonic transition of forms, metamorphosis. The... 
Proteins | Morphogenesis | Enzymes | Insects | Genes | Cell cycle | Phase transitions
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2015, Volume 125, Issue 6, pp. 2375 - 2384
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 504, Issue 7480, pp. 394 - 400
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2014, Volume 46, Issue 9, pp. 1021 - 1027
Journal Article
Nature, ISSN 0028-0836, 09/2018, Volume 561, Issue 7722, pp. 258 - 262
Although serum from patients with Parkinson's disease contains elevated levels of numerous pro-inflammatory cytokines including IL-6, TNF, IL-1 beta, and IFN... 
OXIDATIVE STRESS | ACTIVATION | MUTANTS | MULTIDISCIPLINARY SCIENCES | IN-VIVO MITOPHAGY | DISEASE | NEURONS | DEFICIENT MICE | MUTATIONS | MITOCHONDRIAL-DNA | Protein Kinases - metabolism | Protein Kinases - genetics | Humans | Stress, Physiological | Receptor, Interferon alpha-beta - antagonists & inhibitors | Membrane Proteins - deficiency | Inflammation - metabolism | DNA, Mitochondrial - genetics | Membrane Proteins - metabolism | Parkinson Disease - metabolism | Protein Kinases - deficiency | Physical Conditioning, Animal | Membrane Proteins - genetics | Mice, Inbred C57BL | Alarmins - metabolism | Ubiquitin-Protein Ligases - metabolism | Immunity, Innate | DNA, Mitochondrial - blood | Mitochondrial Degradation | Animals | Receptor, Interferon alpha-beta - immunology | Inflammation - genetics | Ubiquitin-Protein Ligases - deficiency | Inflammation - prevention & control | Mice | Ubiquitin-Protein Ligases - genetics | Inflammation | Genetic aspects | Research | Gene mutations | Risk factors | Ubiquitin | Heart | Cell culture | Oxidative stress | Animal models | Parkinson's disease | Substantia nigra | Parkinsons disease | Innate immunity | Mitochondrial DNA | Kinases | Immunity | Interleukin 6 | Mitochondria | Movement disorders | Ubiquitin-protein ligase | Deoxyribonucleic acid--DNA | Dopamine receptors | Enzymes | Phenotypes | Dopamine | Cytokines | Neurodegenerative diseases | Body temperature | Damage patterns | Insects | Tumor necrosis factor | PTEN-induced putative kinase | Proteomics | Interferon | Parkin protein | Mutation | Methods
Journal Article
Nature, ISSN 0028-0836, 09/2015, Volume 525, Issue 7567, pp. 124 - 128
Mitochondria are involved in a variety of cellular functions, including ATP production, amino acid and lipid biogenesis and breakdown, signalling and... 
APOPTOSIS | MUTANTS | ACID | MITOFUSIN 2 | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | DYNAMICS | DYSFUNCTION | STRESS | DROSOPHILA | PARKINSONS-DISEASE | Humans | JNK Mitogen-Activated Protein Kinases - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Antigens, CD - metabolism | Stearic Acids - metabolism | Drosophila melanogaster - metabolism | Ubiquitination - drug effects | Acetyltransferases - deficiency | Mitochondria - genetics | Larva - drug effects | Larva - genetics | Membrane Proteins - metabolism | Stearic Acids - administration & dosage | Larva - metabolism | Drosophila melanogaster - cytology | Ubiquitin-Protein Ligases - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Receptors, Transferrin - metabolism | Drosophila melanogaster - drug effects | Animals | Mitochondrial Dynamics - drug effects | Diet | Signal Transduction - drug effects | Drosophila Proteins - deficiency | Ubiquitin-Protein Ligases - deficiency | Drosophila Proteins - genetics | HeLa Cells | Ubiquitin-Protein Ligases - genetics | Stearic Acids - pharmacology | Tumor Suppressor Proteins | Mitochondria | Cell receptors | Genetic aspects | Stearic acid | Genetic regulation | Health aspects | Proteins | Insects | Acids | Morphology | Parkinsons disease | Pink | Parkinsons | Drosophila | mitochondria | metabolism | mitofusin | Parkin
Journal Article
Neuron, ISSN 0896-6273, 2003, Volume 40, Issue 1, pp. 25 - 40
Journal Article