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Immunity, ISSN 1074-7613, 2004, Volume 20, Issue 5, pp. 637 - 649
Journal Article
Immunity, ISSN 1074-7613, 06/2009, Volume 30, Issue 6, pp. 789 - 801
Cellular inhibitor of apoptosis proteins (cIAPs) block apoptosis, but their physiological functions are still under investigation. Here, we report that cIAP1... 
MOLIMMUNO | CELLS | ACTIVATION | C-IAP1 | PROTEIN | DROSOPHILA IMD PATHWAY | IN-VIVO | KINASE | IMMUNOLOGY | POLYUBIQUITINATION | NF-KAPPA-B | RIP2 | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Receptors, Pattern Recognition - immunology | Inhibitor of Apoptosis Proteins - genetics | Nod1 Signaling Adaptor Protein - agonists | Colitis - pathology | Baculoviral IAP Repeat-Containing 3 Protein | Nod1 Signaling Adaptor Protein - metabolism | Receptors, Pattern Recognition - metabolism | Signal Transduction - immunology | Receptors, Pattern Recognition - agonists | Nod2 Signaling Adaptor Protein - agonists | Inhibitor of Apoptosis Proteins - metabolism | Colitis - immunology | Receptor-Interacting Protein Serine-Threonine Kinases - immunology | Cytokines - immunology | Cytokines - metabolism | Mice, Inbred C57BL | Nod2 Signaling Adaptor Protein - immunology | Ubiquitination - immunology | Nod1 Signaling Adaptor Protein - immunology | Immunity, Innate | Mice, Knockout | Acetylmuramyl-Alanyl-Isoglutamine - pharmacology | Ubiquitin-Protein Ligases | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Apoptosis - immunology | Colitis - enzymology | Nod2 Signaling Adaptor Protein - metabolism | Signal Transduction - drug effects | Inhibitor of Apoptosis Proteins - immunology | Mice | Ubiquitin | Oligomers | Ligases | Physiological aspects | Crohn's disease | Colitis | Apoptosis | Medical research | Enzymes | Statistical analysis | Cytokines | Kinases | Proteins | Inflammatory bowel disease | Genotype & phenotype | Insects | Bacteria | Gram-negative bacteria | Chemokines | Immune system
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2011, Volume 108, Issue 38, pp. 15966 - 15971
The peritrophic matrix (PM) forms a layer composed of chitin and glycoproteins that lines the insect intestinal lumen. This physical barrier plays a role... 
Bacterial infections | Midgut | Drosophila | Bacteria | Infections | Toxins | Peritrophic membrane | Epithelium | Infestation | Genetic mutation | Innate immunity | Insect immunity | Gut | Entomopathogens | SYSTEM | MEMBRANE | TOLERANCE | MULTIDISCIPLINARY SCIENCES | gut | CRY1AC | insect immunity | GUT IMMUNITY | entomopathogens | innate immunity | ANTIOXIDANT | DROSOCRYSTALLIN | MIDGUT | ENVELOPE | HOST-DEFENSE | Eye Proteins - immunology | Intestinal Mucosa - metabolism | Drosophila melanogaster - immunology | Serratia marcescens - immunology | Serratia marcescens - physiology | Drosophila Proteins - immunology | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Intestines - immunology | Host-Pathogen Interactions - immunology | Signal Transduction - immunology | Bacteria - immunology | Intestinal Mucosa - immunology | Pseudomonas - immunology | Eye Proteins - genetics | Pectobacterium carotovorum - immunology | Microscopy, Electron, Transmission | Bacteria - metabolism | Bacterial Toxins - immunology | Gene Expression Regulation | Intestinal Mucosa - microbiology | Pectobacterium carotovorum - physiology | Reverse Transcriptase Polymerase Chain Reaction | Serratia marcescens - metabolism | Bacterial Toxins - metabolism | Drosophila melanogaster - microbiology | Animals | Intestines - microbiology | Eye Proteins - metabolism | Pseudomonas - physiology | Survival Analysis | Drosophila Proteins - genetics | Mutation | Physiological aspects | Glycoproteins | Genetic aspects | Research | Bacterial genetics | Biological Sciences
Journal Article
Immunity, ISSN 1074-7613, 12/2017, Volume 47, Issue 6, pp. 1197 - 1209.e10
Antibodies against the NANP repeat of circumsporozoite protein (CSP), the major surface antigen of ( ) sporozoites, can protect from malaria in animal models... 
circumsporozoite protein | Plasmodium falciparum | natural infection | affinity maturation | protective antibodies | malaria | memory B cells | epitope specificity | human | X-ray structures | SYSTEM | RESPONSES | IMMUNITY | TRANSMISSION | MEMORY B-CELLS | HUMAN MALARIA | STAGE | PLASMODIUM-FALCIPARUM SPOROZOITES | CIRCUMSPOROZOITE PROTEIN | IMMUNOLOGY | MONOCLONAL-ANTIBODIES | Plasmodium berghei - immunology | Immunoglobulin Heavy Chains - biosynthesis | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Humans | B-Lymphocytes - parasitology | Immunoglobulin Heavy Chains - chemistry | Crystallography, X-Ray | Male | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Sporozoites - immunology | Epitopes - immunology | Sporozoites - chemistry | Immunity, Humoral | Female | Protozoan Proteins - chemistry | Antigens, Protozoan - genetics | Protein Interaction Domains and Motifs | Immunoglobulin Heavy Chains - immunology | Recombinant Proteins - metabolism | Protein Conformation, alpha-Helical | Gene Expression | Antigens, Protozoan - chemistry | Antibodies, Protozoan - immunology | Malaria - immunology | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Antibodies, Protozoan - chemistry | Antibodies, Protozoan - biosynthesis | Malaria - prevention & control | Malaria, Falciparum - parasitology | Animals | B-Lymphocytes - immunology | Protein Conformation, beta-Strand | Malaria - parasitology | Malaria, Falciparum - immunology | Protein Binding | Immunologic Memory | Epitopes - chemistry | Mice | Protozoan Proteins - immunology | Viral antibodies | Wildlife conservation | Malaria | Analysis | Children's hospitals | Malaria vaccine | Antibodies | Development and progression | B cells | Health aspects | Antigenic determinants | Vector-borne diseases | Animal models | Immunological memory | Immunoglobulins | Complementarity | Molecular structure | Vaccines | Epitopes | Parasites | Aquatic insects | Immunity | Disease transmission | Lymphocytes B | Coding | Sporozoites | Monoclonal antibodies | Affinity | Immunity (humoral) | Human behavior | Complementarity-determining region 3 | Binding sites | Circumsporozoite protein
Journal Article
Immunity, ISSN 1074-7613, 11/2013, Volume 39, Issue 5, pp. 976 - 985
Journal Article
Journal Article
PLoS One, ISSN 1932-6203, 2013, Volume 8, Issue 2, p. e55571
BACKGROUND: Gene-based vaccination using prime/boost regimens protects animals and humans against malaria, inducing cell-mediated responses that in animal... 
APICAL MEMBRANE ANTIGEN-1 | SPOROZOITE INOCULATION | VIRUS ANKARA | IMMUNIZATION | NEUTRALIZING ANTIBODIES | MULTIDISCIPLINARY SCIENCES | CIRCUMSPOROZOITE PROTEIN | DOUBLE-BLIND | NAIVE ADULTS | CYTOTOXIC T-LYMPHOCYTES | PHASE 2A TRIAL | Vaccines, DNA - genetics | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Humans | Middle Aged | Vaccines, DNA - immunology | Male | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Young Adult | Malaria Vaccines - adverse effects | Plasmodium falciparum - genetics | Malaria Vaccines - immunology | Adult | Female | Antigens, Protozoan - genetics | Malaria Vaccines - therapeutic use | Membrane Proteins - genetics | Adenoviruses, Human - immunology | Membrane Proteins - immunology | Vaccines, DNA - therapeutic use | Malaria, Falciparum - parasitology | Interferon-gamma - immunology | Vaccines, DNA - adverse effects | Adolescent | Malaria, Falciparum - immunology | Adenoviruses, Human - genetics | CD8-Positive T-Lymphocytes - immunology | Immunity, Cellular | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Antigens | Wildlife conservation | Malaria | Liver | Vaccination | Malaria vaccine | Vaccines | T cells | Plasmodium falciparum | Advertising executives | Mosquitoes | Control | Analysis | Adenoviruses | DNA | Bites and stings | Genetic aspects | Health aspects | Enzyme-linked immunosorbent assay | Flow cytometry | Animal models | Goats | CD8 antigen | Antibodies | Leukocytes (mononuclear) | Lymphocytes T | Parasites | Aquatic insects | Immunity | Immunity (cell-mediated) | Replicating | Acquired immune deficiency syndrome--AIDS | Sporozoites | Peripheral blood mononuclear cells | Deoxyribonucleic acid--DNA | Circumsporozoite protein | Expression vectors | Vector-borne diseases | Medical research | Immunization | Statistical analysis | Diarrhea | Vectors | Membrane proteins | Cytometry | Plasmids | γ-Interferon | Interferon | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS
Journal Article
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 04/2008, Volume 180, Issue 8, pp. 5413 - 5422
Journal Article
PLoS Genetics, ISSN 1553-7390, 07/2018, Volume 14, Issue 7, p. e1007494
Eukaryotic gene expression requires the coordinated action of transcription factors, chromatin remodelling complexes and RNA polymerase. The conserved nuclear... 
CAENORHABDITIS-ELEGANS DEVELOPMENT | RNAI | PROTEIN | ANTIMICROBIAL PEPTIDE EXPRESSION | GENETICS & HEREDITY | GENE-EXPRESSION | RECEPTOR | INFECTION | C. ELEGANS | DROSOPHILA | DEFENSE GENES | Chromatin - metabolism | Caenorhabditis elegans Proteins - immunology | Animals, Genetically Modified | Caenorhabditis elegans - genetics | Gene Expression Regulation - immunology | Homeodomain Proteins - metabolism | Cell Cycle Proteins - metabolism | Caenorhabditis elegans Proteins - metabolism | Mi-2 Nucleosome Remodeling and Deacetylase Complex - metabolism | Homeodomain Proteins - immunology | Immunity, Innate | Mi-2 Nucleosome Remodeling and Deacetylase Complex - immunology | Protein Binding - immunology | Caenorhabditis elegans - immunology | Homeodomain Proteins - genetics | Chromatin Assembly and Disassembly - immunology | Transcription Factors - metabolism | Cell Cycle Proteins - immunology | Animals | Chromatin - immunology | Cell Cycle Proteins - genetics | Transcription Factors - immunology | Caenorhabditis elegans Proteins - genetics | Evolution, Molecular | Cellular proteins | Caenorhabditis elegans | Microbiological research | Immune response | Physiological aspects | Genetic research | Genetic aspects | Research | Gene expression | Medical research | Transcription factors | Peptides | Authorship | Gene regulation | Epidermis | Infections | Genomes | Kinases | DNA-directed RNA polymerase | Chromatin remodeling | Proteins | Molecular evolution | Signal transduction | Insects | Proteomics | Nematodes | Supervision | Worms | Methods | Life Sciences | Immunology | Biochemistry, Molecular Biology | Genomics
Journal Article