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Journal Article
PloS one, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, pp. e63232 - e63232
Autophagy can be induced under nutrition stress conditions. Bcl-2 is a pro-survival protein which inhibits apoptosis and autophagy... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | Microtubule-Associated Proteins - genetics | Nitriles - pharmacology | Microtubule-Associated Proteins - metabolism | Humans | Cell Survival - genetics | Neurons - cytology | Gene Knockdown Techniques | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Neurons - metabolism | Autophagy - genetics | Benzopyrans - pharmacology | Culture Media - chemistry | bcl-2-Associated X Protein - genetics | Beclin-1 | Signal Transduction | Membrane Proteins - genetics | Stress, Physiological - genetics | Gene Expression Regulation | bcl-2-Associated X Protein - metabolism | Cathepsin D - metabolism | Sulfonamides - pharmacology | bcl-2-Associated X Protein - antagonists & inhibitors | Piperazines - pharmacology | Apoptosis Regulatory Proteins - metabolism | Cathepsin D - genetics | Cell Line, Tumor | RNA-Binding Proteins - metabolism | Nutrition | Starvation | Apoptosis | Phosphorylation | Bcl-2 protein | Laboratories | Homeostasis | Activation | Neuroblastoma | Kinases | Autophagy | Proteins | Rodents | Aging | Cathepsin D | Tumorigenesis | Inhibition | Localization | Pharmaceutical sciences | Deprivation | Cell survival | Mortality | Pharmacology | Rapamycin | siRNA | Survival | Substrates | Constraining | Studies | Inhibitors | Insects | Cell death | Annexin V | Phagocytosis | Index Medicus
Journal Article
Nature (London), ISSN 1476-4687, 06/2012, Volume 486, Issue 7401, pp. 80 - 84
..., as well as members of the EGFR and RAF class of proteins (5-7). However, results of this approach have been mixed (8-10). Difficulties include rapidly emerging... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Niacinamide - analogs & derivatives | Proto-Oncogene Proteins c-ret - metabolism | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Male | Phenylurea Compounds | Extracellular Signal-Regulated MAP Kinases - metabolism | Protein Kinase Inhibitors - adverse effects | Drosophila Proteins - metabolism | Molecular Targeted Therapy | Drosophila melanogaster - genetics | Heterocyclic Compounds, 4 or More Rings - pharmacology | Multiple Endocrine Neoplasia Type 2b - genetics | Multiple Endocrine Neoplasia Type 2b - enzymology | Benzenesulfonates - pharmacology | Multiple Endocrine Neoplasia Type 2b - drug therapy | Protein Kinase Inhibitors - chemistry | Polypharmacy | Heterocyclic Compounds, 4 or More Rings - therapeutic use | Drug-Related Side Effects and Adverse Reactions | src-Family Kinases - metabolism | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Drug Evaluation, Preclinical | Drosophila Proteins - antagonists & inhibitors | Disease Models, Animal | src-Family Kinases - antagonists & inhibitors | Heterocyclic Compounds, 4 or More Rings - chemistry | Heterocyclic Compounds, 4 or More Rings - adverse effects | Survival Rate | Drosophila melanogaster - drug effects | Xenograft Model Antitumor Assays | Animals | Signal Transduction - drug effects | Protein Kinase Inhibitors - therapeutic use | Sorafenib | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Cell Transformation, Neoplastic - drug effects | Drosophila Proteins - genetics | Cell Transformation, Neoplastic - pathology | Proto-Oncogene Proteins c-ret - genetics | Chemotherapy | Physiological aspects | Genetic aspects | Cellular signal transduction | Research | Carcinogenesis | Risk factors | Cancer | Proteins | Nuclear magnetic resonance--NMR | Insects | Toxicity | Mutation | Kinases | Drug dosages | Cell adhesion & migration | Index Medicus
Journal Article
PLoS biology, ISSN 1544-9173, 12/2015, Volume 13, Issue 12, pp. e1002318 - e1002318
Detecting danger is one of the foremost tasks for a neural system. Larval parasitoids constitute clear danger to Drosophila, as up to 80% of fly larvae become... 
Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Receptors, Odorant - metabolism | Drosophila melanogaster - physiology | Olfactory Bulb - metabolism | Drosophila Proteins - agonists | Drosophila Proteins - metabolism | Wasps - metabolism | Drosophila melanogaster - genetics | Odorants | Receptors, Odorant - agonists | Terpenes - pharmacology | Protein Isoforms - metabolism | Protein Isoforms - agonists | Larva - drug effects | Behavior, Animal - drug effects | Female | Larva - genetics | Sensory Receptor Cells - metabolism | Alkaloids - pharmacology | Signal Transduction | Animals, Genetically Modified | Nerve Tissue Proteins - agonists | Mutant Proteins - metabolism | Nerve Tissue Proteins - genetics | Drosophila melanogaster - drug effects | Nerve Tissue Proteins - metabolism | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | Sensory Receptor Cells - drug effects | Iridoids - pharmacology | Larva - parasitology | Receptors, Odorant - genetics | Drosophila melanogaster - parasitology | Oviposition | Pyridines - pharmacology | Drosophila Proteins - genetics | Larva - physiology | Olfactory Bulb - drug effects | Mutant Proteins - agonists | Parasitoids | Zoological research | Drosophila | Animal defenses | Physiological aspects | Host-parasite relationships | Behavior | Research | Rhinencephalon | Semiochemicals | Index Medicus | Biological Sciences | Biologi | Naturvetenskap | Natural Sciences | Zoologi | Zoology | Ligands | Insects | Females | Neurons
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 8/2007, Volume 104, Issue 35, pp. 13901 - 13906
Journal Article
PLoS pathogens, ISSN 1553-7374, 04/2015, Volume 11, Issue 4, pp. e1004848 - e1004848
Mosquitoes are natural vectors for many etiologic agents of human viral diseases. Mosquito-borne flaviviruses can persistently infect the mosquito central... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Apoptosis - drug effects | Humans | Brain - virology | Host-Pathogen Interactions - drug effects | Antiviral Agents - metabolism | Phylogeny | Drosophila Proteins - metabolism | Virus Internalization - drug effects | Aedes - virology | Dengue Virus - immunology | Nerve Tissue Proteins - pharmacology | Viral Envelope Proteins - metabolism | Female | Protein Interaction Domains and Motifs | Neurons - drug effects | Insect Proteins - metabolism | Cell Membrane - drug effects | Recombinant Proteins - metabolism | Cell Line | Nerve Tissue Proteins - antagonists & inhibitors | Neurons - virology | Antiviral Agents - pharmacology | Dengue Virus - drug effects | Insect Proteins - pharmacology | Neurons - immunology | Encephalitis Virus, Japanese - physiology | Insect Proteins - genetics | Aedes - drug effects | Aedes - immunology | Recombinant Proteins - pharmacology | Insect Proteins - antagonists & inhibitors | Nerve Tissue Proteins - genetics | Brain - drug effects | Nerve Tissue Proteins - metabolism | Animals | Viral Envelope Proteins - antagonists & inhibitors | Viral Envelope Proteins - chemistry | Dengue Virus - physiology | Encephalitis Virus, Japanese - drug effects | Drosophila Proteins - genetics | Brain - immunology | Drosophila melanogaster | Encephalitis Virus, Japanese - immunology | Index Medicus | Medical research | Encephalitis | Viruses | Nervous system | Infections | Grants | Experiments | Research & development | Proteins | R&D | Mosquitoes | Insects | Viral infections | Polyclonal antibodies
Journal Article
Journal Article