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Toxicon, ISSN 0041-0101, 02/2016, Volume 110, pp. 90 - 109
Ureases are metalloenzymes that hydrolyze urea into ammonia and carbon dioxide. They were the first enzymes to be crystallized and, with them, the notion that... 
Neurotoxicity | Insecticide | Antifungal | Canavalia ensiformis | Helicobacter pylori | Virulence factor | Eicosanoids | Proteolytic activation | Glycine max | Pro-inflammatory activity | URINARY-TRACT-INFECTION | BACILLUS-PASTEURII | VECTOR RHODNIUS-PROLIXUS | NITRIC-OXIDE SYNTHASE | JACK-BEAN UREASE | CANAVALIA-ENSIFORMIS UREASE | HELICOBACTER-PYLORI UREASE | NEUTROPHIL-ACTIVATING PROTEIN | PHARMACOLOGY & PHARMACY | GASTRIC EPITHELIAL-CELLS | CENTRAL-NERVOUS-SYSTEM | TOXICOLOGY | Metalloproteins - toxicity | Humans | Fungicides, Industrial - toxicity | Neurotoxins - genetics | Fungicides, Industrial - pharmacology | Plant Proteins - toxicity | Urease - pharmacology | Metalloproteins - metabolism | Bacterial Proteins - toxicity | Isoenzymes - toxicity | Isoenzymes - metabolism | Apoenzymes - metabolism | Metalloproteins - genetics | Plant Proteins - metabolism | Insecticides - pharmacology | Recombinant Proteins - metabolism | Plant Proteins - pharmacology | Isoenzymes - genetics | Bacterial Proteins - genetics | Neurotoxins - toxicity | Apoenzymes - pharmacology | Recombinant Proteins - pharmacology | Apoenzymes - toxicity | Neurotoxins - pharmacology | Plant Proteins - genetics | Bacterial Proteins - pharmacology | Animals | Insecticides - metabolism | Urease - toxicity | Apoenzymes - genetics | Isoenzymes - pharmacology | Recombinant Proteins - toxicity | Bacterial Proteins - metabolism | Metalloproteins - pharmacology | Neurotoxins - metabolism | Urease - metabolism | Urease - genetics | Insecticides - toxicity | Enzymes | Urea | Bacterial infections | Enzyme inhibitors | Peptides | Proteolysis | Analysis | Physiological aspects | Hydrolases | Virulence (Microbiology) | Metalloenzymes | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, pp. e0148242 - e0148242
Annual losses of honey bee colonies remain high and pesticide exposure is one possible cause. Dangerous combinations of pesticides, plant-produced compounds... 
MALPIGHIAN TUBULES | DRUG INTERACTIONS | APIS-MELLIFERA | GLYCOPROTEIN-MEDIATED TRANSPORT | MULTIDISCIPLINARY SCIENCES | INSECTICIDE TOXICITY | IVERMECTIN | ABC TRANSPORTERS | EXPRESSION | P-GLYCOPROTEIN | TRANSEPITHELIAL TRANSPORT | Niacinamide - analogs & derivatives | Drug Resistance, Multiple | Cyclohexanes - pharmacology | Neonicotinoids | Rhodamines - metabolism | Ivermectin - metabolism | Biphenyl Compounds - pharmacology | Membrane Transport Proteins - metabolism | Biological Transport - drug effects | Carbamates - pharmacology | Pyrazoles - pharmacology | Insecticides - pharmacology | Risk Assessment | Fatty Acids, Unsaturated - pharmacology | Ivermectin - pharmacology | Verapamil - pharmacology | Environmental Exposure - adverse effects | Animals | Quercetin - pharmacology | ATP-Binding Cassette Transporters - drug effects | Bees - drug effects | Pyridines - pharmacology | Niacinamide - pharmacology | Sesquiterpenes - pharmacology | ATP-Binding Cassette Transporters - antagonists & inhibitors | Honeybee | Research | Drug resistance | Health aspects | Ivermectin | Rhodamine | Laboratories | Fluorescence | Insecticides | Biochemistry | Parasites | Tissues | Bees | Proteins | Toxicology | Insecticide resistance | Agrochemicals | Metabolites | Risk assessment | Physiology | Agriculture | Enzymes | Colonies | Multidrug resistance | Pesticides | Hemolymph | Substrate inhibition | Metabolism | Chemicals | Honey | Sensitivity | Antibiotics | Insects | Animal behavior | Quercetin | Strategy | Chemical interactions | Verapamil | In vivo methods and tests | Molecular biology | Transporter | Index Medicus
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 09/2012, Volume 122, Issue 5, pp. 941 - 951
J. Neurochem. (2012) 122, 941951. Abstract In vitro and in vivo models of Parkinsons disease (PD) suggest that increased oxidant production leads to... 
hydroethidine | mitochondria | glycolysis | reactive oxygen species | NADPH OXIDASE | OXYGEN SPECIES PRODUCTION | OXIDATIVE STRESS | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOPAMINERGIC-NEURONS | PARAQUAT | NEUROSCIENCES | BRAIN MITOCHONDRIA | REACTIVE OXYGEN | ANIMAL-MODELS | CELL-CULTURE | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - pharmacology | Insecticides - pharmacology | Rats | Herbicides - pharmacology | Adrenergic Agents - pharmacology | Dose-Response Relationship, Drug | Neurotoxins - pharmacology | Animals | Oligomycins - pharmacology | Oxidopamine - pharmacology | Time Factors | Dopamine Agents - pharmacology | Oxygen Consumption - drug effects | Adenosine Triphosphate - metabolism | Dopaminergic Neurons - metabolism | Proton Ionophores - pharmacology | Rotenone - pharmacology | Superoxides - metabolism | Dopaminergic Neurons - drug effects | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone - pharmacology | Paraquat - pharmacology | Cell Line, Transformed | Energy Metabolism - drug effects | Glucose metabolism | Herbicides | Parkinson's disease | Cell death | Analysis | Superoxide | Mitochondrial DNA | Universities and colleges | Cells | Neurochemistry | Mitochondria | Neurotransmitters | Bioenergetics | Parkinsons disease | Apoptosis | Index Medicus | Dopamine | Neurodegenerative diseases | 6-Hydroxydopamine | Acidification | Data processing | Oxygen consumption | Rotenone | Toxicants | MPP super(+) | Oxidants | Glycolysis | Paraquat | Oxidation | Movement disorders
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2014, Volume 111, Issue 46, pp. 16592 - 16597
Insect repellents are important prophylactic tools for travelers and populations living in endemic areas of malaria, dengue, encephalitis, and other... 
Insect antennae | Receptors | Double stranded RNA | Insect vectors | Female animals | Acetates | Mosquitos | Heptanoic acids | Oocytes | Odorant receptors | ELICIT | MULTIDISCIPLINARY SCIENCES | TERMS | picaridin | DROSOPHILA | Culex quinquefasciatus | RESPONSES | INSECT REPELLENTS | IR 3535 | IONOTROPIC GLUTAMATE RECEPTORS | CHEMICALS | DESIGNATION | ATTRACTANT | odorant receptor | southern house mosquito | Receptors, Ionotropic Glutamate - physiology | Smell - genetics | Receptors, Odorant - biosynthesis | Receptors, Ionotropic Glutamate - genetics | Electrophysiology | Molecular Sequence Data | Recombinant Fusion Proteins - metabolism | Smell - physiology | Piperidines - pharmacology | RNA Interference | Aldehydes - pharmacology | beta-Alanine - pharmacology | Cloning, Molecular | Culex - drug effects | Receptors, Odorant - physiology | Female | Transcription, Genetic | beta-Alanine - analogs & derivatives | Arthropod Antennae - physiology | Avoidance Learning | Insect Repellents - pharmacology | Xenopus laevis | Culex - physiology | Cyclopentanes - pharmacology | DEET - pharmacology | Feeding Behavior - physiology | Feeding Behavior - drug effects | Menthol - analogs & derivatives | Animals | Menthol - pharmacology | Oxylipins - pharmacology | Receptors, Odorant - genetics | Acetates - pharmacology | Models, Neurological | Receptors, Odorant - drug effects | Insecticides | Health aspects | Mosquitoes | Index Medicus | Biological Sciences
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 07/2000, Volume 12, Issue 7, pp. 2475 - 2485
Nicotinic acetylcholine receptors (nAChRs) are expressed in the midbrain ascending dopaminergic system, a target of many addictive drugs. Here we assessed the... 
choline | nicotine | Ca2 | mesencephalon | dopaminergic neurons | Dopaminergic neurons | Mesencephalon | Choline | Nicotine | CA2+ CHANNELS | RELEASE | RAT STRIATAL SYNAPTOSOMES | NEUROSCIENCES | MIDBRAIN DOPAMINERGIC-NEURONS | IMMUNOCYTOCHEMICAL LOCALIZATION | MESSENGER-RNA | CENTRAL-NERVOUS-SYSTEM | DIVERSITY | BRAIN | SUBUNIT | Glycine - analogs & derivatives | Calcium - metabolism | Dihydro-beta-Erythroidine - pharmacology | 2-Amino-5-phosphonovalerate - pharmacology | Endoplasmic Reticulum - metabolism | Substantia Nigra - cytology | Nicotine - pharmacology | Mice, Mutant Strains | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Indoles - pharmacology | Fura-2 | Tetrodotoxin - pharmacology | Action Potentials - drug effects | Nicotinic Agonists - pharmacology | Insecticides - pharmacology | Nifedipine - pharmacology | Receptors, Nicotinic - metabolism | Neurons - chemistry | Presynaptic Terminals - chemistry | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Presynaptic Terminals - physiology | Tyrosine 3-Monooxygenase - analysis | Aconitine - analogs & derivatives | Aconitine - pharmacology | Calcium Channel Blockers - pharmacology | Action Potentials - physiology | Patch-Clamp Techniques | Polyamines - pharmacology | Animals | Glycine - pharmacology | Neurons - enzymology | Choline - pharmacology | Benzoates - pharmacology | Mice | In Vitro Techniques | Receptors, Nicotinic - genetics | Substantia Nigra - physiology | Fluorescent Dyes | Nootropic Agents - pharmacology | Bungarotoxins - pharmacology
Journal Article