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PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0135690 - e0135690
Background Pulmonary drug delivery is characterized by short onset times of the effects and an increased therapeutic ratio compared to oral drug delivery. This... 
ORGANIC CATION TRANSPORTERS | LUNG | RESPIRATORY-TRACT | INTRATRACHEAL INSTILLATION | MULTIDISCIPLINARY SCIENCES | CELL-CULTURE MODELS | CALU-3 CELLS | P-GLYCOPROTEIN ACTIVITY | LINE CALU-3 | EXPOSURE | DELIVERY | Drug Evaluation, Preclinical - methods | Bronchodilator Agents - administration & dosage | Epithelial Cells - drug effects | Humans | Cells, Cultured | Administration, Inhalation | Aerosols - administration & dosage | Equipment Design | Fluorescein - pharmacokinetics | Bronchodilator Agents - pharmacokinetics | Drug Evaluation, Preclinical - instrumentation | Budesonide, Formoterol Fumarate Drug Combination - pharmacokinetics | Fluorescein - administration & dosage | Formoterol Fumarate - pharmacokinetics | Aerosols - pharmacokinetics | Budesonide - administration & dosage | Rhodamine 123 - administration & dosage | Budesonide - pharmacokinetics | Budesonide, Formoterol Fumarate Drug Combination - administration & dosage | Cell Membrane - drug effects | Drug Combinations | Nebulizers and Vaporizers | Formoterol Fumarate - administration & dosage | Rhodamine 123 - pharmacokinetics | Drugs | Usage | Drug delivery systems | Powders | Fluorescein | Comparative analysis | Health aspects | Vehicles | Cell culture | Rhodamine | Budesonide | Membranes | Lung | Mucus | Drug delivery | Powder | Nanoparticles | Respiratory tract | Proteins | Engineering | Pore size | Formoterol | Polyvinyl alcohol | Chronic obstructive pulmonary disease | Drug dosages | Formulations | Medical research | Tightness | Permeability | Epithelium | Penetration | Monolayers | Aerosols | Porosity | Pharmaceuticals | Index Medicus
Journal Article
Journal Article
Neurotoxicology and Teratology, ISSN 0892-0362, 2015, Volume 51, pp. 68 - 76
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2008, Volume 233, Issue 2, pp. 276 - 285
Recently, many studies have shown that nanoparticles can translocate from the lungs to the circulatory system. As a particulate foreign body, nanoparticles... 
Metal nanoparticles | Matrix metalloproteinases | Tissue inhibitors of metalloproteinases | Human monocyte cell line U937 | CELLS | PARTICLES | TRANSITION-METALS | FREE-RADICALS | IN-VITRO | INTRATRACHEAL INSTILLATION | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | ULTRAFINE CARBON-BLACK | C-JUN | NORMOXIC LUNG ISCHEMIA | Gene Expression Regulation, Enzymologic - drug effects | Transcription Factor AP-1 - drug effects | Transcription, Genetic - drug effects | Reactive Oxygen Species - metabolism | Protein-Tyrosine Kinases - metabolism | Humans | Titanium - administration & dosage | Enzyme Precursors - drug effects | Monocytes - metabolism | Transcription Factor AP-1 - metabolism | Gelatinases - drug effects | Dose-Response Relationship, Drug | Nanoparticles | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 2 - drug effects | Time Factors | U937 Cells | Gelatinases - metabolism | Protein-Tyrosine Kinases - drug effects | Matrix Metalloproteinase 2 - metabolism | Cobalt - administration & dosage | Monocytes - drug effects | Titanium - toxicity | Cobalt - toxicity | Enzyme Precursors - metabolism | Signal Transduction - drug effects | Matrix Metalloproteinase 9 - drug effects | Oxidative Stress - drug effects | Tyrosine | Oxidative stress | Cysteine | Messenger RNA | Phenols | Health aspects | Cobalt | Titanium dioxide | Public health | Nanotechnology | Isoflavones | Index Medicus | CURCUMIN | LUNGS | TITANIUM OXIDES | TRANSCRIPTION | MONOCYTES | CYSTEINE | NANOSTRUCTURES | TOXICITY | 60 APPLIED LIFE SCIENCES | DOSES | TYROSINE | INFLAMMATION | COBALT
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, pp. e70618 - e70618
Background: With a wide range of applications, titanium dioxide (TiO2) nanoparticles (NPs) are manufactured worldwide in large quantities. Recently, in the... 
RESPONSES | INTRATRACHEAL INSTILLATION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | INHALATION | RATS | ULTRAFINE | PARTICLE-SIZE | Liver - pathology | Injections, Intravenous | Kidney - pathology | Titanium - administration & dosage | Male | Hematologic Tests | Spleen - drug effects | Toxicity Tests, Acute | Micronucleus Tests | Liver - drug effects | Behavior, Animal - drug effects | Female | Spleen - pathology | Lung - pathology | Kidney - drug effects | Nanoparticles - toxicity | Brain - drug effects | Titanium - toxicity | Eating - drug effects | Organ Size - drug effects | Animals | Lung - drug effects | Brain - pathology | Drinking - drug effects | Mice | Nanoparticles - administration & dosage | Nanoparticles | Analysis | Liver | Health aspects | Blood cell count | Titanium dioxide | Histochemistry | Heart | Brain | Surgical implants | Particle size | Intravenous administration | Physical activity | Toxicity | Syngeneic grafts | Body weight | Lung | Genotoxicity | Science | Blood | Toxicology | Histopathology | Rodents | Titanium | Biocompatibility | Public health | Spleen | Scanning electron microscopy | Kidneys | Hematology | Pathological effects | Nanomaterials | Injection | Studies | White blood cells | Food intake | Brain damage | Laboratory animals | Brain injury | Nanotechnology | Acute toxicity | Index Medicus
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2005, Volume 352, Issue 9, pp. 865 - 874
Journal Article
Toxicology Letters, ISSN 0378-4274, 04/2014, Volume 226, Issue 1, pp. 28 - 34
Journal Article
Journal Article
Journal Article