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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2011, Volume 108, Issue 4, pp. 1657 - 1662
Circadian (daily) rhythms are present in almost all plants and animals. In mammals, a brain clock located in the hypothalamic suprachiasmatic nucleus maintains... 
Obesity | Brain | Neurons | Body temperature | Mice | Circadian rhythm | Metabolism | Insulin | Behavioral neuroscience | T tests | Biological clock | Structural plasticity | Cognitive function | Neuronal remodeling | cognitive function | LEPTIN | DEPRESSION | MULTIDISCIPLINARY SCIENCES | RATS | neuronal remodeling | structural plasticity | biological clock | SUPRACHIASMATIC NUCLEUS | MEDIAL PREFRONTAL CORTEX | CONSEQUENCES | RESISTANCE | WEIGHT-GAIN | MICE | BODY | Motor Activity - physiology | Brain - cytology | Maze Learning - physiology | Humans | Mice, Inbred C57BL | Behavior, Animal - physiology | Male | Weight Gain - physiology | Circadian Rhythm - physiology | Photoperiod | Body Temperature - physiology | Insulin - blood | Prefrontal Cortex - cytology | Brain - physiology | Animals | Leptin - blood | Biological Clocks - physiology | Neurons - physiology | Blood Glucose - metabolism | Energy Metabolism - physiology | Circadian Clocks - physiology | Prefrontal Cortex - physiology | Circadian rhythms | Physiological aspects | Cognition | Health aspects | Human subjects | Neurosciences | Rodents | Physiology | Models | Index Medicus | Suprachiasmatic nucleus | Cortex (prefrontal) | Executive function | Cognitive ability | CLOCK protein | Hormones | Hypothalamus | Housing | Light effects | Emotions | Travel | Sleep | Biological Sciences
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2010, Volume 16, Issue 4, pp. 438 - 445
Class Ia phosphoinositide 3-kinase (PI3K), an essential mediator of the metabolic actions of insulin, is composed of a catalytic (p110 alpha or p110 beta) and... 
MEDICINE, RESEARCH & EXPERIMENTAL | METABOLIC SYNDROME | PHOSPHATIDYLINOSITOL 3-KINASE | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOPLASMIC-RETICULUM STRESS | P85-ALPHA SUBUNIT | CELL BIOLOGY | SKELETAL-MUSCLE | MESSENGER-RNA | INSULIN-RESISTANCE | PURIFICATION METHOD | ADIPOSE-TISSUE | Insulin - physiology | Endoplasmic Reticulum - metabolism | Activating Transcription Factor 6 | Phosphatidylinositol 3-Kinases - metabolism | Cell Nucleus - physiology | X-Box Binding Protein 1 | Endoribonucleases - physiology | Gene Knockdown Techniques | Trans-Activators - physiology | DNA-Binding Proteins - metabolism | Cell Nucleus - metabolism | Membrane Proteins - physiology | Stress, Physiological - physiology | Cell Line | Unfolded Protein Response - drug effects | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Protein-Serine-Threonine Kinases - physiology | Liver - metabolism | Endoplasmic Reticulum - physiology | Regulatory Factor X Transcription Factors | Transcription Factors - metabolism | Animals | Tunicamycin - pharmacology | Liver - physiology | Phosphatidylinositol 3-Kinases - physiology | Mice | Apoptosis - physiology | Unfolded Protein Response - physiology | Transcription factors | Physiological aspects | Causes of | Insulin resistance | Genetic aspects | Research | Binding proteins | Protein kinases | Catalysis | Kinases | Metabolism | Protein folding | Insulin | Index Medicus
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 05/2006, Volume 100, Issue 5, pp. 1657 - 1665
The present study was designed to examine the effects of lifestyle modification on key contributing factors to atherogenesis, including oxidative stress,... 
Matrix metalloproteinase-9 | Lipids | Nitric oxide | Atherosclerosis | Cell adhesion molecules | atherosclerosis | C-REACTIVE PROTEIN | LIFE-STYLE MODIFICATION | AORTIC ENDOTHELIAL-CELLS | SPORT SCIENCES | lipids | cell adhesion molecules | nitric oxide | PHYSIOLOGY | matrix metalloproteinase-9 | LOW-DENSITY-LIPOPROTEIN | WEIGHT-LOSS | ADHESION MOLECULES | INSULIN-RESISTANCE | CARDIOVASCULAR-DISEASE | LOW-FAT DIET | CORONARY-ARTERY-DISEASE | Matrix Metalloproteinase 9 - physiology | Motor Activity - physiology | Humans | Lipids - physiology | Middle Aged | Oxidative Stress - physiology | Cell Communication - physiology | Male | Insulin - blood | Obesity - blood | Metabolic Syndrome - blood | Chemotaxis - physiology | Lipids - blood | Metabolic Syndrome - physiopathology | Monocytes - pathology | Superoxides - metabolism | Chemokine CCL2 - physiology | Intercellular Adhesion Molecule-1 - blood | Chemokine CCL2 - metabolism | C-Reactive Protein - analysis | Monocytes - physiology | Matrix Metalloproteinase 9 - blood | Intercellular Adhesion Molecule-1 - physiology | Blood Glucose - analysis | Cells, Cultured | Endothelium, Vascular - physiopathology | Metabolic Syndrome - therapy | Nitric Oxide - physiology | Obesity - physiopathology | Vascular Cell Adhesion Molecule-1 - physiology | C-Reactive Protein - physiology | Feeding Behavior - physiology | Hydrogen Peroxide - metabolism | Obesity - pathology | P-Selectin - physiology | P-Selectin - blood | Endothelium, Vascular - pathology | Aged | Nitric Oxide - metabolism | Vascular Cell Adhesion Molecule-1 - metabolism | Inflammation - physiopathology | Index Medicus
Journal Article
Biogerontology, ISSN 1389-5729, 2013, Volume 14, Issue 3, pp. 303 - 323
During ageing skeletal muscles undergo a process of structural and functional remodelling that leads to sarcopenia, a syndrome characterized by loss of muscle... 
Life Sciences | Sarcopenia | FoxO | Geriatrics/Gerontology | Ageing | mTOR | IGF1 | Akt | Developmental Biology | Cell Biology | LIFE-SPAN | IGF-I | ALPHA-V-BETA-3 INTEGRIN | PLASMINOGEN-ACTIVATOR INHIBITOR-1 | GERIATRICS & GERONTOLOGY | GROWTH-HORMONE | MESSENGER-RNA | GENETIC-DETERMINANTS | FAST-TWITCH | CELL-CYCLE | S6 KINASE | Microtubule-Associated Proteins - genetics | SKP Cullin F-Box Protein Ligases - genetics | Humans | SKP Cullin F-Box Protein Ligases - physiology | Male | Forkhead Transcription Factors - physiology | Ubiquitin-Protein Ligases - physiology | Tripartite Motif Proteins | Young Adult | Aged, 80 and over | Adult | Female | Mice, Inbred DBA | Models, Animal | TOR Serine-Threonine Kinases - physiology | Muscle Proteins - physiology | Serpin E2 - physiology | Mice, Inbred C57BL | Mice, Transgenic | Proto-Oncogene Proteins c-akt - physiology | Muscle, Skeletal - physiology | Mice, Knockout | Microtubule-Associated Proteins - physiology | Muscle Proteins - genetics | Autophagy-Related Protein 7 | Sarcopenia - physiopathology | Serpin E2 - genetics | Animals | Aging - physiology | Insulin-Like Growth Factor I - physiology | Adolescent | Signal Transduction - physiology | Aged | Forkhead Box Protein O1 | Mice | Ubiquitin-Protein Ligases - genetics | Ubiquitin | Muscles | Ligases | Proteolysis | Analysis | Index Medicus | SKP Cullin F-Box Protein Ligases | Muscle Proteins | Aging | Serpin E2 | Signal Transduction | Biochemistry, Molecular Biology | Microtubule-Associated Proteins | Insulin-Like Growth Factor I | Proto-Oncogene Proteins c-akt | Ubiquitin-Protein Ligases | TOR Serine-Threonine Kinases | Muscle, Skeletal | Forkhead Transcription Factors | Clinical Medicine | Neurology | Neurologi | Medical and Health Sciences | Medicin och hälsovetenskap | Clinical Neurophysiology | Klinisk neurofysiologi | Klinisk medicin
Journal Article
2006, ISBN 9780120884841, 365
The somatotropic axis is one of the major hormonal systems regulating postnatal growth in mammals. It interacts with the central nervous system on several... 
Somatotropin | Somatotropin-Releasing Hormone | Somatomedins | Neuroendocrinology | Growth Hormone | Neuroendorinology | physiology | Growth hormone releasing factor | Receptors, Somatotropin | Clinical & internal medicine
eBook
Cell Metabolism, ISSN 1550-4131, 07/2013, Volume 18, Issue 1, pp. 86 - 98
Journal Article
Cell Metabolism, ISSN 1550-4131, 07/2013, Volume 18, Issue 1, pp. 106 - 117
Journal Article
PLoS genetics, ISSN 1553-7390, 11/2018, Volume 14, Issue 11, pp. e1007767 - e1007767
Behavior and physiology are orchestrated by neuropeptides acting as central neuromodulators and circulating hormones. An outstanding question is how these... 
CELLS | RESPONSES | HOMEOSTASIS | PEPTIDES | GENE | GENETICS & HEREDITY | RECEPTOR | ABLATION | IDENTIFICATION | EXPRESSING NEURONS | NUTRIENT SENSOR | Receptors, Neuropeptide - deficiency | Motor Activity - physiology | Drosophila melanogaster - physiology | Insulin - physiology | Male | Gene Expression Profiling | Neuropeptides - physiology | Drosophila melanogaster - genetics | Gene Knockdown Techniques | Postprandial Period - physiology | Neurons - classification | Drosophila Proteins - physiology | Neurons - physiology | Female | Neuropeptides - genetics | Energy Metabolism - genetics | Energy Metabolism - physiology | Receptors, Neuropeptide - physiology | Neuropeptides - deficiency | Signal Transduction | Animals, Genetically Modified | Receptors, Neuropeptide - genetics | Behavior, Animal - physiology | Diuresis - genetics | Motor Activity - genetics | Animals | Drosophila Proteins - deficiency | Postprandial Period - genetics | Drosophila Proteins - genetics | Mutation | Diuresis - physiology | Physiological aspects | Neuropeptides | Drosophila | Metabolic rate | Diuresis | Starvation | Feeding behavior | Calcium | Peptides | Funding | Neurons | Zoology | Homeostasis | Chemoreception | Gene expression | Renal tubules | Insulin | Neuromodulation | Neuroendocrine system | Ganglia | Feeding | Sleep | Insects | Physiology | Behavior | Locomotor activity | Index Medicus
Journal Article