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1. Full Text Health-related quality of life in paediatric patients with Type 1 diabetes mellitus using insulin infusion systems. A systematic review and meta-analysis
by Rosner, Bastian and Roman-Urrestarazu, Andres
PLoS ONE, ISSN 1932-6203, 06/2019, Volume 14, Issue 6, pp. e0217655 - e0217655
In 2017, more than 1.1 million children were living with type 1 diabetes mellitus (T1DM) globally. The goal in paediatric diabetes therapy is reaching optimal... 
Care and treatment | Type 1 diabetes | Patient outcomes | Analysis | Children | Epidemiology | Health aspects | Quality of life | Type 2 diabetes | Complications and side effects | Pediatrics | Mortality | Insulin | Public health | Diabetes therapy | Therapy | Complications | Diabetes mellitus | Youth | Systematic review | Diabetes mellitus (insulin dependent) | Metabolism | Studies | Infusion | Teenagers | Diabetes | Physical therapy
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2. Full Text ProAct Study: New Features of Insulin Pumps Improve Diabetes Management and Glycemic Control in Patients after Transition of Continuous Subcutaneous Insulin Infusion Systems
by Ziegler, Ralph and Tubili, Claudio and Chico, Ana and Guerci, Bruno and Lundberg, Elena and Borchert, Marcus and Löffler, Andrea and Bloethner, Sandra and Weissmann, Jörg and Pfützner, Andreas
Diabetes Technology & Therapeutics, ISSN 1520-9156, 09/2013, Volume 15, Issue 9, pp. 738 - 743
Background: Continuous subcutaneous insulin infusion (CSII) patients experience switches of pump systems on a regular basis. We investigated the impact of... 
Original Articles | THERAPY | METABOLIC-CONTROL | GLUCOSE | ENDOCRINOLOGY & METABOLISM | Glycated Hemoglobin A - analysis | Hypoglycemic Agents - therapeutic use | Prospective Studies | Blood Glucose - analysis | Europe | Humans | Middle Aged | Diabetes Mellitus - drug therapy | Insulin - administration & dosage | Male | Infusions, Subcutaneous | Hypoglycemic Agents - administration & dosage | Adult | Female | Insulin Infusion Systems | Aged | Blood Glucose - metabolism | Insulin - therapeutic use | Usage | Patient outcomes | Insulin pumps | Research | Comparative analysis | Methods | Diabetes therapy | Index Medicus
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3. Full Text Studying the hypothalamic insulin signal to peripheral glucose intolerance with a continuous drug infusion system into the mouse brain
by Ajoy, Reni and Chou, Szu-Yi
Journal of Visualized Experiments, ISSN 1940-087X, 01/2018, Volume 2018, Issue 131
Insulin regulates systematic metabolism in the hypothalamus and the peripheral insulin response. An inflammatory reaction in peripheral adipose tissues... 
Medicine | Glucose metabolism | Insulin tolerance | Chemokine (C-C motif) ligand 5 (CCL5) | Issue 131 | Type 2 diabetes mellitus (T2DM) | Micro-osmotic pump | Brain drug delivery | micro-osmotic pump | PHOSPHORYLATION | RANTES | insulin tolerance | MULTIDISCIPLINARY SCIENCES | BLOOD-GLUCOSE | chemokine (C-C motif) ligand 5 (CCL5) | type 2 diabetes mellitus (T2DM) | INFLAMMATION | LIVER | RESISTANCE | ACUTE STROKE | CCR5 | glucose metabolism | Index Medicus
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4. Full Text Diabetes Technology—Continuous Subcutaneous Insulin Infusion Therapy and Continuous Glucose Monitoring in Adults: An Endocrine Society Clinical Practice Guideline
by Peters, Anne L and Ahmann, Andrew J and Battelino, Tadej and Evert, Alison and Hirsch, Irl B and Murad, M. Hassan and Winter, William E and Wolpert, Howard
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 11/2016, Volume 101, Issue 11, pp. 3922 - 3937
Objective: To formulate clinical practice guidelines for the use of continuous glucose monitoring and continuous subcutaneous insulin infusion in adults with... 
MULTIPLE DAILY INJECTIONS | COMPLICATIONS TRIAL/EPIDEMIOLOGY | SEVERE HYPOGLYCEMIA | BOLUS CALCULATOR | AMERICAN ASSOCIATION | ENDOCRINOLOGY & METABOLISM | QUALITY-OF-LIFE | IMPROVED GLYCEMIC CONTROL | PUMP THERAPY | METABOLIC-CONTROL | EUROPEAN ASSOCIATION | Endocrinology - methods | Drug Monitoring - trends | Combined Modality Therapy - trends | Humans | Diabetes Mellitus, Type 2 - diet therapy | Diabetes Mellitus, Type 1 - therapy | Hypoglycemia - prevention & control | Exercise | Monitoring, Ambulatory - trends | Hypoglycemic Agents - administration & dosage | Monitoring, Ambulatory - adverse effects | Diabetes Mellitus, Type 2 - therapy | Adult | Hypoglycemia - chemically induced | Patient Education as Topic | Precision Medicine | Hypoglycemic Agents - therapeutic use | Hyperglycemia - prevention & control | Blood Glucose - analysis | Insulin Infusion Systems - adverse effects | Insulin - administration & dosage | Combined Modality Therapy - adverse effects | Evidence-Based Medicine | Consensus | Insulin Infusion Systems - trends | Diabetes Mellitus, Type 1 - drug therapy | Diabetes Mellitus, Type 2 - blood | International Agencies | Diabetes Mellitus, Type 1 - blood | Societies, Scientific | Diabetes Mellitus, Type 1 - diet therapy | Diet, Diabetic - adverse effects | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Insulin - adverse effects | Insulin - therapeutic use | Index Medicus | Abridged Index Medicus
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5. Full Text Day and Night Closed-Loop Control in Adults With Type 1 Diabetes A comparison of two closed-loop algorithms driving continuous subcutaneous insulin infusion versus patient self-management
by Luijf, Yoeri M and DeVries, J. Hans and Zwinderman, Koos and Leelarathna, Lalantha and Nodale, Marianna and Caldwell, Karen and Kumareswaran, Kavita and Elleri, Daniela and Allen, Janet M and Wilinska, Malgorzata E and Evans, Mark L and Hovorka, Roman and Doll, Werner and Ellmerer, Martin and Mader, Julia K and Renard, Eric and Place, Jerome and Farret, Anne and Cobelli, Claudio and del Favero, Simone and Dalla Man, Chiara and Avogaro, Angelo and Bruttomesso, Daniela and Filippi, Alessio and Scotton, Rachele and Magni, Lalo and Lanzola, Giordano and Di Palma, Federico and Soru, Paola and Toffanin, Chiara and de Nicolao, Giuseppe and Arnolds, Sabine and Benesch, Carsten and Heinemann, Lutz and AP Home Consortium and AP@home Consortium and on behalf of the AP@home Consortium
Diabetes care, ISSN 0149-5992, 2013, Volume 36, Issue 12, pp. 3882 - 3887
OBJECTIVETo compare two validated closed-loop (CL) algorithms versus patient self-control with CSII in terms of glycemic control.RESEARCH DESIGN AND... 
ENDOCRINE PANCREAS | ARTIFICIAL PANCREAS | GLUCOSE CONTROL | ENDOCRINOLOGY & METABOLISM | DELIVERY | Follow-Up Studies | Infusion Pumps | Humans | Insulin - administration & dosage | Male | Treatment Outcome | Administration, Cutaneous | Equipment Design | Diabetes Mellitus, Type 1 - drug therapy | Cross-Over Studies | Blood Glucose Self-Monitoring - methods | Algorithms | Hypoglycemic Agents - administration & dosage | Diabetes Mellitus, Type 1 - blood | Adult | Female | Insulin Infusion Systems | Blood Glucose - metabolism | Self Care - methods | Glucose metabolism | Care and treatment | Type 1 diabetes | Blood sugar | Adults | Internet service providers | Insulin | Diabetes therapy | Self control | Glycemic index | Diabetes | Patients | Index Medicus | Original Research
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6. Full Text Continuous insulin infusion systems in type 2 diabetes
by Kesavadev, Jothydev
Journal of Association of Physicians of India, ISSN 0004-5772, 04/2011, Volume 59, Issue 2011, pp. 41 - 43
There are various delivery devices available for insulin like syringes, pens, and insulin pumps. Syringes have drawbacks like dosage errors and pain. Insulin... 
Hypoglycemic Agents - therapeutic use | History, 20th Century | Humans | Insulin - administration & dosage | Clinical Trials as Topic | India | Infusions, Subcutaneous | Patient Selection | Insulin Infusion Systems - history | Hypoglycemic Agents - administration & dosage | Quality of Life | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Insulin - therapeutic use | Insulin Infusion Systems - utilization | Index Medicus
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7. An automatic insulin infusion system based on LQG control technique
by Patra, Akshaya Kumar and Rout, Pravat Kumar
International Journal of Biomedical Engineering and Technology, ISSN 1752-6418, 2015, Volume 17, Issue 3, pp. 252 - 275
This paper makes an attempt to develop clinical simulation model of glucose-insulin interaction and to design an optimal controller to regulate the Blood... 
Insulin infusion | LQG control | H | Glucose regulation | control | Diabetes | PID control | Linear quadratic Gaussian control | Effectiveness | Computer simulation | Delivery systems | Automatic control | Control systems | Gaussian | Patients | Insulin | Optimization
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8. Pumping insulin
: everything you need for success on a smart insulin pump
by Walsh, John, P.A and Roberts, Ruth, M.A
2006, 4th ed., ISBN 1884804861, xviii, 332
Insulin pumps
Book
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9. Full Text Changes in basal insulin infusion rates with subcutaneous insulin infusion: Time until a change in metabolic effect is induced in patients with type 1 diabetes
by Heinemann, Lutz and Nosek, Leszek and Kapitza, Christoph and Schweitzer, Matthias-Axel and Krinelke, Lars
Diabetes Care, ISSN 0149-5992, 08/2009, Volume 32, Issue 8, pp. 1437 - 1439
OBJECTIVE - Evaluation of the time required until a change in the basal insulin infusion rate with an insulin pump induces subsequent changes in the metabolic... 
INTERVAL | THERAPY | ABSORPTION | ENDOCRINOLOGY & METABOLISM | CSII | Infusion Pumps, Implantable | Humans | Middle Aged | Glucose Clamp Technique - methods | Insulin - administration & dosage | Male | Diabetes Mellitus, Type 1 - drug therapy | Infusions, Subcutaneous | Blood Glucose - drug effects | Diabetes Mellitus, Type 1 - blood | Adult | Fatty Acids, Nonesterified - blood | Insulin Infusion Systems | Blood Glucose - metabolism | Insulin - therapeutic use | Care and treatment | Research | Glucose | Type 1 diabetes | Insulin | Dextrose | Changes | Studies | Diabetes | Clinical medicine | Metabolic syndrome | Index Medicus | Original Research
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10. Full Text Comparison of a multiple daily insulin injection regimen (basal once-daily glargine plus mealtime lispro) and continuous subcutaneous insulin infusion (lispro) in type 1 diabetes: A randomized open parallel multicenter study
by Bolli, Geremia B and Kerr, David and Thomas, Reena and Torlone, Elisabetta and Sola-Gazagnes, Agnès and Vitacolonna, Ester and Selam, Jean Louis and Home, Philip D
Diabetes Care, ISSN 0149-5992, 07/2009, Volume 32, Issue 7, pp. 1170 - 1176
OBJECTIVE - Insulin pump therapy (continuous subcutaneous insulin infusion [CSII]) and multiple daily injections (MDIs) with insulin glargine as basal insulin... 
NPH INSULIN | TRIAL | GLYCEMIC CONTROL | DETEMIR | METAANALYSIS | PHARMACOKINETICS | ENDOCRINOLOGY & METABOLISM | GLUCOSE VARIABILITY | PEOPLE | MELLITUS | ACTING INSULIN | Hypoglycemia - epidemiology | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Glycated Hemoglobin A - drug effects | Male | Hypoglycemic Agents - administration & dosage | Injections, Subcutaneous | Adult | Female | Insulin Infusion Systems | Insulin - analogs & derivatives | Hypoglycemic Agents - therapeutic use | Insulin, Long-Acting | Drug Administration Schedule | Insulin - administration & dosage | Diabetes Mellitus, Type 1 - drug therapy | Insulin Lispro | Blood Glucose - drug effects | Insulin Glargine | Age of Onset | Kinetics | Blood Glucose - metabolism | Hypoglycemic Agents - adverse effects | Insulin - adverse effects | Insulin - therapeutic use | Diabetics | Research | Type 1 diabetes | Insulin | Analysis | Diabetes therapy | Studies | Injections | Comparative studies | Clinical trials | Diabetes | Hypoglycemia | Drug therapy | Index Medicus | Original Research
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11. Assessment of use of specific features of subcutaneous insulin infusion systems and their relationship to metabolic control in patients with type 1 diabetes
by Quiros, C and Patrascioiu, I and Gimenez, M and Vinagre, I and Vidal, M and Jansa, M and Conget, I
ENDOCRINOLOGIA Y NUTRICION, ISSN 1575-0922, 06/2014, Volume 61, Issue 6, pp. 318 - 322
Background and objective: Patients with type 1 diabetes (T1DM) treated with continuous subcutaneous insulin infusion (CSII) have the availability of several... 
Glycemic control | BOLUS CALCULATOR | SEVERE HYPOGLYCEMIA | EFFICACY | ENDOCRINOLOGY & METABOLISM | Insulin infusion systems | Type 1 diabetes mellitus | Glycated Hemoglobin A - analysis | User-Computer Interface | Humans | Middle Aged | Male | Equipment Design | Dose-Response Relationship, Drug | Adult | Female | Insulin Infusion Systems | Retrospective Studies | Software Design | Infusion Pumps, Implantable | Blood Glucose - analysis | Blood Glucose Self-Monitoring - utilization | Insulin - administration & dosage | Treatment Outcome | Diabetes Mellitus, Type 1 - drug therapy | Infusions, Subcutaneous | Algorithms | Diabetes Mellitus, Type 1 - blood | Computer Systems | Software | Blood Glucose Self-Monitoring - instrumentation | Insulin - therapeutic use
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12. Full Text An Insulin Infusion Advisory System Based on Autotuning Nonlinear Model-Predictive Control
by Zarkogianni, K and Vazeou, A and Mougiakakou, S. G and Prountzou, A and Nikita, K. S
IEEE Transactions on Biomedical Engineering, ISSN 0018-9294, 09/2011, Volume 58, Issue 9, pp. 2467 - 2477
This paper aims at the development and evaluation of a personalized insulin infusion advisory system (IIAS), able to provide real-time estimations of the... 
Artificial pancreas (AP) | Recurrent neural networks | Predictive models | Prediction algorithms | personalized model | Biochemistry | Insulin | autotuning model-predictive control | Sugar | Tuning | type I diabetes mellitus (T1DM) | ENGINEERING, BIOMEDICAL | type 1 diabetes mellitus (T1DM) | GLUCOSE | ALGORITHM | Blood Glucose - analysis | Humans | Diabetes Mellitus, Type 1 - drug therapy | Algorithms | Models, Biological | Computer Simulation | Diabetes Mellitus, Type 1 - blood | Signal Processing, Computer-Assisted | Adult | Insulin Infusion Systems | Blood Glucose - metabolism | Nonlinear Dynamics | Fuzzy Logic | Pancreas, Artificial | Precision Medicine | Fuzzy logic | Robust statistics | Technology application | Usage | Synthetic training devices | Analysis | Physiological aspects | Fuzzy algorithms | Mathematical models | Diabetes | Fuzzy systems | Neural networks | Index Medicus
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13. Full Text Implementation of a Safe and Effective Insulin Infusion Protocol in a Medical Intensive Care Unit
by Philip A. Goldberg and Mark D. Siegel and Robert S. Sherwin and Joshua I. Halickman and Michelle Lee and Valerie A. Bailey and Sandy L. Lee and James D. Dziura and Silvio E. Inzucchi
Diabetes Care, ISSN 0149-5992, 02/2004, Volume 27, Issue 2, pp. 461 - 467
Implementation of a Safe and Effective Insulin Infusion Protocol in a Medical Intensive Care Unit Philip A. Goldberg , MD 1 , Mark D. Siegel , MD 2 , Robert S.... 
DIABETES-MELLITUS | GLUCOSE INFUSION | MORTALITY | MANAGEMENT | ADMISSION | ENDOCRINOLOGY & METABOLISM | ACUTE MYOCARDIAL-INFARCTION | ACUTE STROKE | RISK | STRESS HYPERGLYCEMIA | CRITICALLY ILL PATIENTS | Intensive Care Units | Reproducibility of Results | Humans | Middle Aged | Male | Insulin Infusion Systems - standards | Connecticut | Adult | Female | Aged | Safety | Blood Glucose - metabolism | Continental Population Groups | APACHE | Case studies | Intensive care units | Diabetics | Blood sugar | Insulin pumps | Comparative analysis | Health aspects | Critical care | Glucose | Protocol | Insulin | Nurses | Index Medicus
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14. Full Text Continuous Subcutaneous Insulin Infusion (CSII) of Insulin Aspart Versus Multiple Daily Injection of Insulin Aspart/Insulin Glargine in Type 1 Diabetic Patients Previously Treated With CSII
by Irl B. Hirsch and Bruce W. Bode and Satish Garg and Wendy S. Lane and Allen Sussman and Peter Hu and Olga M. Santiago and Jerzy W. Kolaczynski and Insulin Aspart CSII MDI Comparison and Insulin Aspart CSII/MDI Comparison Study Group and for the Insulin Aspart CSII/MDI Comparison Study Group
Diabetes Care, ISSN 0149-5992, 03/2005, Volume 28, Issue 3, pp. 533 - 538
Continuous Subcutaneous Insulin Infusion (CSII) of Insulin Aspart Versus Multiple Daily Injection of Insulin Aspart/Insulin Glargine in Type 1 Diabetic... 
NPH INSULIN | GLYCEMIC CONTROL | THERAPY | REDUCTION | EFFICACY | ENDOCRINOLOGY & METABOLISM | HYPOGLYCEMIA | RANDOMIZED-TRIAL | LISPRO | Body Mass Index | Glycated Hemoglobin A - analysis | Insulin, Long-Acting | Drug Administration Schedule | Humans | Insulin - administration & dosage | Male | Biomarkers - blood | Diabetes Mellitus, Type 1 - drug therapy | Fructosamine - blood | Insulin Aspart | Insulin Glargine | Adult | Female | Insulin Infusion Systems | Insulin - analogs & derivatives | Blood Glucose - metabolism | Insulin - therapeutic use | Diabetics | Care and treatment | Dosage and administration | Insulin | Injections | Diabetes | Drug therapy | Index Medicus
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15. Full Text Pharmacological properties of faster‐acting insulin aspart vs insulin aspart in patients with type 1 diabetes receiving continuous subcutaneous insulin infusion: A randomized, double‐blind, crossover trial
by Heise, Tim and Zijlstra, Eric and Nosek, Leszek and Rikte, Tord and Haahr, Hanne
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 02/2017, Volume 19, Issue 2, pp. 208 - 215
Aim: To evaluate the pharmacological characteristics of faster-acting insulin aspart (faster aspart) compared with insulin aspart (IAsp) during continuous... 
pharmacokinetics | type 1 diabetes | pharmacodynamics | insulin pump therapy | POSTPRANDIAL GLYCEMIA | MANAGEMENT | EFFICACY | ANALOGS | SAFETY | MELLITUS | IMPACT | HYPERGLYCEMIA | ENDOCRINOLOGY & METABOLISM | IDEAL INSULIN | ONSET | Double-Blind Method | Area Under Curve | Humans | Middle Aged | Diabetes Mellitus, Type 1 - metabolism | Male | Diabetes Mellitus, Type 1 - drug therapy | Hypoglycemic Agents - pharmacology | Infusions, Subcutaneous | Blood Glucose - drug effects | Cross-Over Studies | Insulin Aspart - administration & dosage | Hypoglycemic Agents - administration & dosage | Insulin Aspart - pharmacology | Least-Squares Analysis | Adult | Female | Insulin Infusion Systems | Glucose Clamp Technique | Blood Glucose - metabolism | Care and treatment | Type 1 diabetes | Analysis | Clinical trials | Glucose | Insulin | Dextrose | Diabetes | Index Medicus | Original
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16. Full Text Application of zone model predictive control artificial pancreas during extended use of infusion set and sensor: A randomized crossover-controlled home-use trial
by Forlenza, Gregory P and Deshpande, Sunil and Ly, Trang T and Howsmon, Daniel P and Cameron, Faye and Baysal, Nihat and Mauritzen, Eric and Marcal, Tatiana and Towers, Lindsey and Bequette, B. Wayne and Huyett, Lauren M and Pinsker, Jordan E and Gondhalekar, Ravi and Doyle, Francis J and Maahs, David M and Buckingham, Bruce A and Dassau, Eyal
Diabetes Care, ISSN 0149-5992, 08/2017, Volume 40, Issue 8, pp. 1096 - 1102
OBJECTIVE As artificial pancreas (AP) becomes standard of care, consideration of extended use of insulin infusion sets (IIS) and continuous glucose monitors... 
B-CELLS | AUTOIMMUNE | HELIOS | ENDOCRINOLOGY & METABOLISM | REGULATORY T-CELLS | INTERLEUKIN-35 | IL-15 | C-PEPTIDE | IL-35 | EXPRESSION | Hypoglycemic Agents - therapeutic use | Glycated Hemoglobin A - metabolism | Humans | Male | Diabetes Mellitus, Type 1 - therapy | Cross-Over Studies | Young Adult | Outpatients | Adolescent | Adult | Female | Insulin Infusion Systems | Blood Glucose - metabolism | Smartphone | Insulin - therapeutic use | Pancreas, Artificial | Usage | Control | Blood sugar | Infusion therapy | Therapy | Clinical trials | Glycemic index | Glucose | Insulin | SAP protein | Infusion | Randomization | Wear | Safety engineering | Adults | Research design | Mathematical models | Diabetes | Safety | Pancreas | Environmental monitoring | Remote monitoring | Predictive control | Index Medicus | Emerging Technologies and Therapeutics
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