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Journal Article
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2012, Volume 18, Issue 8, pp. 1279 - 1285
Toll-like receptor 4 (TLR4) has a key role in innate immunity by activating an inflammatory signaling pathway. Free fatty acids (FFAs) stimulate adipose tissue... 
PATHWAYS | MEDICINE, RESEARCH & EXPERIMENTAL | ADIPOCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | FACTOR-KAPPA-B | SATURATED FATTY-ACIDS | DIET-INDUCED OBESITY | CELL BIOLOGY | TOLL-LIKE RECEPTOR-4 | CHRONIC INFLAMMATION | EXPRESSION | ADIPOSE-TISSUE | INNATE IMMUNITY | Inflammation - chemically induced | Humans | Molecular Sequence Data | NF-kappa B - metabolism | Adipocytes - drug effects | Fatty Acids, Nonesterified - pharmacology | Adipocytes - physiology | Obesity - blood | Insulin Resistance - physiology | Base Sequence | alpha-2-HS-Glycoprotein - antagonists & inhibitors | Toll-Like Receptor 4 - antagonists & inhibitors | Binding Sites | Cytokines - genetics | Toll-Like Receptor 4 - analysis | Blood Glucose - analysis | Obesity - physiopathology | Toll-Like Receptor 4 - chemistry | 3T3-L1 Cells | alpha-2-HS-Glycoprotein - physiology | Mice, Knockout | Gene Expression Regulation - drug effects | Toll-Like Receptor 4 - physiology | Receptors, Leptin - deficiency | Diabetes Mellitus, Type 2 - blood | alpha-2-HS-Glycoprotein - toxicity | Animals | Diabetes Mellitus, Type 2 - physiopathology | alpha-2-HS-Glycoprotein - chemistry | Signal Transduction - drug effects | Galactosides - metabolism | Ligands | Mice, Obese | Signal Transduction - physiology | Mice | Mice, Inbred BALB C | Chronic Disease | Dietary Fats - toxicity | Cytokines - biosynthesis | Adipocytes - chemistry | Inflammation - physiopathology | Insulin resistance | Alpha fetoproteins | Care and treatment | Diagnosis | Health aspects | Ligands (Biochemistry) | Signal transduction | Lipids | Cytokines | Gene expression | Immune system | Index Medicus
Journal Article
Journal Article
Journal Article
Cell Metabolism, ISSN 1550-4131, 07/2013, Volume 18, Issue 1, pp. 106 - 117