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Journal Article
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 04/2015, Volume 17, Issue 4, pp. 386 - 394
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 02/2016, Volume 18, Issue 2, pp. 159 - 168
Aims: To compare the immunogenicity profiles and the potential effects on clinical outcomes of LY2963016 insulin glargine (LY IGlar) and Lantus (R) insulin... 
insulin antibody | biosimilar insulin | LY2963016 | insulin glargine | Insulin glargine | Insulin antibody | Biosimilar insulin | LY2963016 insulin glargine | CONTROLLED-TRIAL | RESPONSES | EFFICACY | SAFETY | ENDOCRINOLOGY & METABOLISM | NAIVE | Immunogenetic Phenomena - drug effects | Recombinant Proteins - therapeutic use | Insulin, Regular, Human - genetics | Humans | Diabetes Mellitus, Type 1 - complications | Insulin Antibodies - analysis | Recombinant Proteins - adverse effects | Incidence | Hypoglycemia - prevention & control | Diabetes Mellitus, Type 2 - immunology | Diabetes Mellitus, Type 1 - immunology | Drug Hypersensitivity - complications | Hypoglycemia - chemically induced | Diabetes Mellitus, Type 2 - complications | Drug Hypersensitivity - etiology | Hypoglycemic Agents - therapeutic use | Hyperglycemia - prevention & control | Biosimilar Pharmaceuticals - therapeutic use | Insulin Glargine - adverse effects | Double-Blind Method | Insulin Glargine - therapeutic use | Asymptomatic Diseases - epidemiology | Insulin, Regular, Human - adverse effects | Insulin, Regular, Human - analogs & derivatives | Insulin, Regular, Human - therapeutic use | Biosimilar Pharmaceuticals - adverse effects | Diabetes Mellitus, Type 1 - drug therapy | Cross Reactions | Insulin Glargine - analogs & derivatives | Diabetes Mellitus, Type 2 - blood | Drug Hypersensitivity - epidemiology | Drug Hypersensitivity - immunology | Diabetes Mellitus, Type 1 - blood | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Type 2 diabetes | Care and treatment | Comparative analysis | Insulin | Index Medicus | Original
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 02/2018, Volume 20, Issue 2, pp. 400 - 408
Aims: MK-1293 is an insulin glargine that has an amino acid sequence identical to that of Lantus, the originator insulin glargine. Two euglycaemic clamp... 
pharmacokinetics | biosimilar insulin | type 1 diabetes | glycaemic control | insulin analogues | pharmacodynamics | SUBCUTANEOUS INJECTION | METABOLITES | NPH INSULIN | BIOTRANSFORMATION | ULTRALENTE | ENDOCRINOLOGY & METABOLISM | EXPOSURE | United States | Humans | Male | Insulin Glargine - pharmacokinetics | Patient Dropouts | Hypoglycemia - prevention & control | Young Adult | Hypoglycemic Agents - blood | Biotransformation | Biosimilar Pharmaceuticals - pharmacokinetics | Adult | Female | Hypoglycemia - chemically induced | Hypoglycemic Agents - therapeutic use | Hyperglycemia - prevention & control | Biosimilar Pharmaceuticals - therapeutic use | Hypoglycemic Agents - pharmacokinetics | Insulin Glargine - adverse effects | Blood Glucose - analysis | Double-Blind Method | Insulin Glargine - therapeutic use | Biosimilar Pharmaceuticals - blood | Biosimilar Pharmaceuticals - adverse effects | Diabetes Mellitus, Type 1 - drug therapy | Cross-Over Studies | Insulin Glargine - analogs & derivatives | European Union | Diabetes Mellitus, Type 1 - blood | Glucose Clamp Technique | Hypoglycemic Agents - adverse effects | Medical research | Metabolites | Type 1 diabetes | Analysis | Medicine, Experimental | Amino acids | Dosage and administration | Research | Insulin | Studies | Amino acid sequence | Diabetes mellitus (insulin dependent) | Diabetes | Diabetes mellitus | Index Medicus | Original
Journal Article
Journal Article
Journal Article
Journal Article