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Journal Article
Journal Article
Journal Article
Diabetes Care, ISSN 0149-5992, 2014, Volume 37, Issue 8, pp. 2317 - 2325
Journal Article
Journal Article
Diabetes Care, ISSN 0149-5992, 10/2014, Volume 37, Issue 10, pp. 2763 - 2773
OBJECTIVE: Mealtime insulin is commonly added to manage hyperglycemia in type 2 diabetes when basal insulin is insufficient. However, this complex regimen is... 
CONTROLLED-TRIAL | GLYCEMIC CONTROL | ORAL-THERAPY | COMBINATION THERAPY | PARALLEL-GROUP | EXENATIDE | ENDOCRINOLOGY & METABOLISM | OPEN-LABEL | TREATED PATIENTS | TREATMENT SATISFACTION | GETGOAL-L | Glycated Hemoglobin A - analysis | Hypoglycemia - epidemiology | Humans | Middle Aged | Body Weight - drug effects | Male | Hyperglycemia - drug therapy | Metformin - adverse effects | Peptides - administration & dosage | Hypoglycemic Agents - administration & dosage | Venoms - administration & dosage | Female | Metformin - administration & dosage | Hypoglycemia - chemically induced | Meals | Receptors, Glucagon - agonists | Drug Administration Schedule | Venoms - adverse effects | Insulin - administration & dosage | Treatment Outcome | Insulin Lispro - administration & dosage | Blood Glucose - drug effects | Insulin, Long-Acting - adverse effects | Diabetes Mellitus, Type 2 - blood | Insulin, Long-Acting - administration & dosage | Glucagon-Like Peptide-1 Receptor | Insulin Glargine | Insulin Lispro - adverse effects | Quality of Life | Aged | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Insulin - adverse effects | Peptides - adverse effects | Type 2 diabetes | Care and treatment | Dosage and administration | Hypoglycemia | Insulin | Weight gain | Health aspects | Risk factors | Diabetes | Glucose | Medical treatment | Quality of life | Index Medicus
Journal Article
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 07/2014, Volume 54, Issue 7, pp. 792 - 799
ABSTRACTLY2605541 is a novel basal insulin analog with a prolonged duration of action. Two Phase I studies assessed LY2605541 pharmacokinetics (PK),... 
pharmacokinetics | glucodynamics | long‐acting basal insulin | long-acting basal insulin | DETEMIR | MANAGEMENT | EFFICACY | TO-TARGET TRIAL | NPH INSULIN | GLARGINE | THERAPY | PHARMACOLOGY & PHARMACY | ENDOGENOUS INSULIN | SECRETION | TYPE-1 | Drugs, Investigational - adverse effects | Humans | Middle Aged | Drugs, Investigational - pharmacokinetics | Half-Life | Insulin Lispro - pharmacokinetics | Polyethylene Glycols - adverse effects | Biological Availability | Male | Metabolic Clearance Rate | Drugs, Investigational - analysis | Insulin, Long-Acting - blood | Dose-Response Relationship, Drug | Young Adult | Hypoglycemic Agents - blood | Hypoglycemic Agents - administration & dosage | Injections, Subcutaneous | Insulin Lispro - blood | Adult | Female | Hypoglycemic Agents - pharmacokinetics | Reproducibility of Results | Blood Glucose - analysis | Insulin, Long-Acting - pharmacokinetics | Polyethylene Glycols - pharmacokinetics | Insulin Lispro - administration & dosage | Polyethylene Glycols - administration & dosage | Cross-Over Studies | Insulin, Long-Acting - adverse effects | Insulin, Long-Acting - administration & dosage | Insulin Glargine | Drugs, Investigational - administration & dosage | Insulin Lispro - adverse effects | Glucose Clamp Technique | Infusions, Intravenous | Hypoglycemic Agents - adverse effects | Cohort Studies | Usage | Half-life (Nuclear physics) | Analysis | Clinical trials | Dosage and administration | Research | Pharmacokinetics | Insulin | Index Medicus
Journal Article