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Clinical Epigenetics, ISSN 1868-7075, 01/2016, Volume 8, Issue 1, p. 11
Background: Insulin-like growth factors 1 and 2 (IGF1 and IGF2) and their binding proteins (IGFBPs) are expressed in the placenta and known to regulate fetal... 
DNA methylation | Placental expression | Small fetus | Large fetus | Insulin growth factor | HUMAN PLACENTA | FACTOR-II | 5-METHYLCYTOSINE | GENE-EXPRESSION PATTERNS | FETUS | IMPRINTED GENES | HORMONE | MESSENGER-RNA | ONCOLOGY | GENETICS & HEREDITY | BINDING-PROTEIN 3 | IGF-II | Insulin-Like Growth Factor Binding Protein 3 - genetics | Insulin-Like Growth Factor Binding Proteins - physiology | Insulin-Like Growth Factor II - physiology | Humans | Fetal Growth Retardation - genetics | Insulin-Like Growth Factor I - genetics | Promoter Regions, Genetic - genetics | Case-Control Studies | DNA Methylation | Insulin-Like Growth Factor II - genetics | Fetal Growth Retardation - etiology | Adult | Female | Insulin-Like Growth Factor Binding Protein 4 - physiology | Insulin-Like Growth Factor Binding Protein 2 - physiology | Infant, Newborn | Insulin-Like Growth Factor Binding Protein 3 - physiology | Insulin-Like Growth Factor Binding Proteins - genetics | Insulin-Like Growth Factor Binding Protein 1 - physiology | Insulin-Like Growth Factor Binding Protein 4 - genetics | Insulin-Like Growth Factor Binding Protein 2 - genetics | Placenta - metabolism | Pregnancy | Insulin-Like Growth Factor I - physiology | Infant, Small for Gestational Age | Insulin-Like Growth Factor Binding Protein 1 - genetics | Infants (Newborn) | Epigenetic inheritance | RNA | Growth | Genes | Gene expression | Purines | Pyrimidines | Fetus | Binding proteins | Methylation | Protein binding
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 9, pp. 3475 - 3480
Insulin-like growth factor-binding protein 2 (IGFBP2) is increasingly recognized as a glioma oncogene, emerging as a target for therapeutic intervention. In... 
Cell motility | Glioma | Genes | Medical treatment | Cell lines | Small interfering RNA | Mice | Integrins | Tumors | Cancer | ACTIVATION | GLIOBLASTOMA | MULTIDISCIPLINARY SCIENCES | THERAPEUTIC TARGET | IGFBP2 | ILK | MICE | OPPORTUNITIES | MODEL | IDENTIFICATION | EXPRESSION | Genetic Therapy | Nestin | Insulin-Like Growth Factor Binding Protein 2 - toxicity | Prognosis | Genetic Vectors - administration & dosage | Oligodendroglioma - genetics | Humans | Neoplasm Proteins - physiology | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Genetic Vectors - therapeutic use | Receptors, Virus - genetics | I-kappa B Proteins - genetics | Integrin beta1 - physiology | Glioblastoma - genetics | Intermediate Filament Proteins - genetics | Oligodendroglioma - metabolism | I-kappa B Proteins - toxicity | Insulin-Like Growth Factor Binding Protein 2 - physiology | Neoplasm Proteins - genetics | Astrocytoma - genetics | Astrocytoma - metabolism | NF-KappaB Inhibitor alpha | Genes, sis | Neoplasm Invasiveness | Neoplasm Proteins - biosynthesis | Protein-Serine-Threonine Kinases - physiology | Genes, Synthetic | Kaplan-Meier Estimate | Brain Neoplasms - genetics | Retroviridae | Mice, Transgenic | Nerve Tissue Proteins - genetics | Disease Progression | Insulin-Like Growth Factor Binding Protein 2 - genetics | Glioblastoma - therapy | Animals | Protein-Serine-Threonine Kinases - toxicity | Glioblastoma - pathology | Brain Neoplasms - therapy | NF-kappa B - physiology | Cell Line, Tumor | Signal Transduction - physiology | Insulin-Like Growth Factor Binding Protein 2 - biosynthesis | Avian Proteins - genetics | Biological Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, p. e0154256
Insulin-like growth factor (IGF) signalling plays a key role in homing, progression, and treatment resistance in multiple myeloma (MM). In the extracellular... 
BREAST-CANCER | INSULIN | MURINE MODEL | IGFBP-2 | MULTIDISCIPLINARY SCIENCES | RECEPTOR | FACTOR-I | BORTEZOMIB | EXPRESSION | FIBROBLASTS | INHIBITS TUMOR-GROWTH | Insulin-Like Growth Factor Binding Protein 3 - genetics | Prognosis | Monoclonal Gammopathy of Undetermined Significance - genetics | Humans | Middle Aged | Monoclonal Gammopathy of Undetermined Significance - diagnosis | Gene Expression Regulation, Neoplastic | Male | Insulin-Like Growth Factor I - genetics | Case-Control Studies | Insulin-Like Growth Factor II - genetics | Insulin-Like Growth Factor Binding Protein 3 - metabolism | Monoclonal Gammopathy of Undetermined Significance - blood | Bone Marrow - metabolism | Female | Multiple Myeloma - blood | Enzyme-Linked Immunosorbent Assay | Multiple Myeloma - diagnosis | Signal Transduction | Insulin-Like Growth Factor Binding Protein 2 - metabolism | Insulin-Like Growth Factor II - metabolism | Insulin-Like Growth Factor Binding Protein 2 - genetics | Insulin-Like Growth Factor Binding Protein 1 - metabolism | Multiple Myeloma - pathology | Monoclonal Gammopathy of Undetermined Significance - pathology | Bone Marrow - pathology | Protein Binding | Aged | Insulin-Like Growth Factor I - metabolism | Multiple Myeloma - genetics | Insulin-Like Growth Factor Binding Protein 1 - genetics | Bone marrow | Cellular signal transduction | Research | Binding proteins | Insulin-like growth factor 1 | Multiple myeloma | Homing behavior | Insulin-like growth factor I | Insulin-like growth factor-binding protein 2 | Insulin-like growth factor-binding protein 1 | Gammopathy | Insulin-like growth factors | Homing | Proteins | Immunology | Compartments | Fibroblasts | Insulin-like growth factor-binding protein 3 | Insulin-like growth factor II | Physical growth | Enzyme-linked immunosorbent assay | Hematology | Monoclonal gammopathy | Breast cancer | Bioavailability | Metabolism | Gene expression | Insulin | Patients | Signaling | Medical prognosis | Protein expression | Internet | Bone | Receptor mechanisms | Endocrinology
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, p. e0171344
Background Idiopathic pulmonary fibrosis (IPF) is a rare lung disease of unknown origin leading rapidly to death. This paper addresses the issue of whether... 
YKL-40 LEVELS | INTERSTITIAL LUNG-DISEASES | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | KL-6 | ASTHMA | SERUM | IDIOPATHIC PULMONARY-FIBROSIS | INTERLEUKIN-8 | SARCOIDOSIS | BRONCHOALVEOLAR LAVAGE | Interleukin-8 - genetics | Pulmonary Disease, Chronic Obstructive - diagnosis | Sputum - cytology | Gene Expression | Idiopathic Pulmonary Fibrosis - genetics | Cross-Sectional Studies | Humans | Male | Idiopathic Pulmonary Fibrosis - metabolism | Insulin-Like Growth Factor Binding Protein 2 - metabolism | Sputum - metabolism | Insulin-Like Growth Factor Binding Protein 2 - genetics | Matrix Metalloproteinase 7 - genetics | Idiopathic Pulmonary Fibrosis - diagnosis | Matrix Metalloproteinase 7 - metabolism | Biomarkers | Female | Leukocyte Count | Interleukin-8 - metabolism | Pulmonary Disease, Chronic Obstructive - metabolism | Respiratory Function Tests | Pulmonary Disease, Chronic Obstructive - genetics | Pulmonary fibrosis | Sputum | Genetic aspects | Research | Diagnosis | Biological markers | Gene expression | Insulin-like growth factor I | Epithelial cells | Insulin-like growth factor-binding protein 2 | Insulin-like growth factor-binding protein 1 | Insulin-like growth factors | Kinases | Macrophages | Respiratory tract | Interleukin 6 | Proteins | Respiratory tract diseases | Insulin-like growth factor-binding protein 3 | Chronic obstructive pulmonary disease | Bioindicators | Interleukin 8 | Cytokines | Sarcoidosis | Leukocytes (eosinophilic) | Lung diseases | Leukocytes (neutrophilic) | Inflammation | Interleukin 13 | Tumor necrosis factor-α | Surfactants | Patients | Gelatinase B | Fibrosis | Ambulatory care | Matrilysin | Eosinophils
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2017, Volume 12, Issue 3, p. e0173890
MicroRNAs are small noncoding RNAs that post-transcriptionally control the expression of genes involved in glioblastoma multiforme (GBM) development. Although... 
METASTASIS | NFIA | MIR-302B | MULTIDISCIPLINARY SCIENCES | EXPANSION | SENSITIVITY | PROLIFERATION | TRANSCRIPTION FACTOR | CARCINOMA | EXPRESSION | TEMOZOLOMIDE | NFI Transcription Factors - antagonists & inhibitors | Humans | Transcriptome | Cell Survival - genetics | Apoptosis - genetics | MicroRNAs - metabolism | Gene Regulatory Networks | NFI Transcription Factors - genetics | Gene Knockdown Techniques | Glioma - metabolism | Glioma - genetics | NFI Transcription Factors - metabolism | Glioblastoma - genetics | Glioma - pathology | Glioblastoma - metabolism | Astrocytes - cytology | Promoter Regions, Genetic | Signal Transduction | Down-Regulation | Insulin-Like Growth Factor Binding Protein 2 - metabolism | Insulin-Like Growth Factor Binding Protein 2 - genetics | Glioblastoma - pathology | Cell Line, Tumor | Insulin-Like Growth Factor Binding Protein 2 - antagonists & inhibitors | MicroRNAs - genetics | Apoptosis - physiology | Astrocytes - metabolism | Genetic aspects | MicroRNA | Research | Gene expression | Glioblastoma multiforme | Insulin-like growth factor 1 | Post-transcription | Biotechnology | Cell culture | Transcription factors | Target recognition | Insulin-like growth factor-binding protein 2 | Genomics | Genes | Glioblastoma | Biology | Insulin-like growth factors | Biochemistry | Kinases | Tissues | ADP | Caspase-3 | Proteins | Signal transduction | Cell growth | Ribose | Glioma cells | Tumorigenesis | Medical research | Immunoglobulins | Astrocytes | Mortality | MiRNA | Caspase | Breast cancer | Tumor cell lines | Ribonucleic acid--RNA | Insulin | Survival | Medicine | Polymerase | Signaling | DNA microarrays | Cell death | MicroRNAs | Pharmacy | Cell lines | Stem cells | Tumor suppressor genes | Viability | Apoptosis | RNA | Ribonucleic acid
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 02/2016, Volume 35, Issue 6, pp. 738 - 747
Journal Article
Journal Article
General and Comparative Endocrinology, ISSN 0016-6480, 2011, Volume 171, Issue 3, pp. 326 - 331
Highlights ► A cDNA for salmon IGFBP-3 was cloned for the first time. ► Salmon IGFBP-3 does not correspond to circulating 41-kDa IGFBP. ► Salmon 41-kDa IGFBP... 
Endocrinology & Metabolism | Identification | Gene duplication | Insulin-like growth factor binding protein | Splicing variants | Salmon | N-glycosylation | SYSTEM | LOCALIZATION | COMPLEX | SERUM | FACTOR-I | GLYCOSYLATION | OREOCHROMIS-MOSSAMBICUS | ENDOCRINOLOGY & METABOLISM | COHO SALMON | ACID-LABILE SUBUNIT | EXPRESSION | Insulin-Like Growth Factor Binding Protein 3 - genetics | Amino Acid Sequence | Insulin-Like Growth Factor Binding Protein 2 - classification | Insulin-Like Growth Factor Binding Proteins - genetics | Fish Proteins - chemistry | Insulin-Like Growth Factor Binding Protein 2 - chemistry | Insulin-Like Growth Factor Binding Protein 3 - chemistry | Fish Proteins - metabolism | Molecular Sequence Data | Phylogeny | Reverse Transcriptase Polymerase Chain Reaction | Insulin-Like Growth Factor Binding Protein 2 - metabolism | Fish Proteins - classification | Insulin-Like Growth Factor Binding Protein 2 - genetics | Insulin-Like Growth Factor Binding Proteins - metabolism | Sequence Homology, Amino Acid | Fish Proteins - genetics | Insulin-Like Growth Factor Binding Protein 3 - classification | Animals | Insulin-Like Growth Factor Binding Protein 3 - metabolism | Insulin-Like Growth Factor Binding Proteins - chemistry | Insulin-Like Growth Factor Binding Proteins - classification | Somatotropin | Universities and colleges | Protein binding
Journal Article
Journal Article